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KEGG DRUG

Search results

No.

DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

Acetylcysteine

[4] Acetylcysteine; N acetyl cysteine; N-Acetyl cysteine; N-acetylcysteine

[1] Acetylcysteine 💬

[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
20	Adrenoleukodystrophy
21	Mitochondrial disease
34	Neurofibromatosis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
58	Hypertrophic cardiomyopathy
63	Idiopathic thrombocytopenic purpura
85	Idiopathic interstitial pneumonia
90	Retinitis pigmentosa
94	Primary sclerosing cholangitis
97	Ulcerative colitis
111	Congenital myopathy
164	Oculocutaneous albinism
193	Prader-Willi syndrome
233	Wolfram syndrome
296	Biliary atresia
298	Hereditary pancreatitis
299	Cystic fibrosis
303	Usher syndrome
337	Homocystinuria

Anastrozole

[1] Anastrozole

[1] Anastrozole 💬

[1] CYP19A1 💬

[2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬

[3] 78, 86, 193 💬

Beloranib

[1] Beloranib

[1] 193 💬

Cannabidiol

[1] Cannabidiol

[1] Cannabidiol 💬

[2] CNR1,
CNR2 💬

[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬

[20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
51	Scleroderma
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
140	Dorabe syndrome
144	Lennox-Gastaut syndrome
145	West syndrome
156	Rett syndrome
157	Sturge-Weber syndrome
158	Tuberous sclerosis
193	Prader-Willi syndrome
206	Fragile X syndrome
226	Interstitial cystitis with Hunners ulcer
271	Ankylosing spondylitis

Carbetocin

[1] Carbetocin

[1] Carbetocin 💬

[1] OXTR 💬

[5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬

[1] 193 💬

Choline

[2] Choline; Choline Chloride

[1] Choline 💬

[4] 93, 171, 193, 299 💬

Diazoxide

[2] Diazoxide; DIAZOXIDE CHOLINE

[2] Diazoxide ,
Diazoxide choline 💬

[2] ABCC8,
KCNJ11 💬

[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬

[2] 13, 193 💬

Exenatide

[1] Exenatide

[1] Exenatide 💬

[1] GLP1R 💬

[4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬

[6] 6, 17, 72, 78, 193, 233 💬

Gold

[1] Gold

[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
5	Progressive supranuclear palsy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
17	Multiple system atrophy
19	Lysosomal storage disease
21	Mitochondrial disease
22	Moyamoya disease
28	Systemic amyloidosis
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
53	Sjogren syndrome
54	Adult still disease
56	Behcet disease
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
60	Aplastic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
68	Ossification of the ligamentum flavum
71	Idiopathic osteonecrosis of the femoral head
75	Cushing disease
76	Pituitary gonadotropin secretion hyperthyroidism
77	Growth hormone secreting pituitary adenoma
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
91	Budd-Chiari syndrome
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
127	Frontotemporal lobar degeneration
137	Focal cortical dysplasia
158	Tuberous sclerosis
162	Pemphigoid
167	Marfan syndrome
171	Wilson disease
193	Prader-Willi syndrome
206	Fragile X syndrome
215	Tetralogy of Fallot
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
226	Interstitial cystitis with Hunners ulcer
227	Osler disease
228	Bronchiolitis obliterans
230	Alveolar hypoventilation syndrome
235	Hypoparathyroidism
271	Ankylosing spondylitis
291	Hirschsprung disease, entire colon type
294	Congenital diaphragmatic hernia
296	Biliary atresia
298	Hereditary pancreatitis
299	Cystic fibrosis
310	Congenital anomalies syndrome
318	Citrin deficiency
331	Idiopathic multicentric castleman disease
340	Primary ciliary dyskinesia

Guanfacine

[1] Guanfacine

[2] Guanfacine hydrochloride ,
Guanfacine 💬

[1] ADRA2A 💬

[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬

[1] 193 💬

Liraglutide

[1] Liraglutide

[1] Liraglutide 💬

[1] GLP1R 💬

[4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬

[5] 6, 13, 75, 77, 193 💬

Livoletide

[1] Livoletide

[1] 193 💬

Medical air

[1] Medical air

[1] Air, medical 💬

[3] 85, 86, 193 💬

Metoprolol

[2] Metoprolol; Metoprolol succinate

[4] Metoprolol tartrate ,
Metoprolol succinate ,
Metoprolol ,
Metoprolol fumarate 💬

[1] ADRB1 💬

[13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[6] 17, 57, 58, 113, 193, 226 💬

Metyrapone

[1] METYRAPONE

[1] Metyrapone 💬

[1] CYP11B1 💬

[3] Cortisol synthesis and secretion, Cushing syndrome, Steroid hormone biosynthesis 💬

[2] 75, 193 💬

NNZ-2591

[1] NNZ-2591

[2] 193, 201 💬

Octreotide

[4] OCTREOTIDA; OCTREOTIDE; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE

[5] Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate ,
Octreotide hydrochloride 💬

Name	Other Names
Octreotide	Octreotide
Octreotide acetate	Octreotide diacetate Sandostatin
Octreotide pamoate	Octreotide pamoate
Octreotide acetate	Sandostatin BYNFEZIA PEN MYCAPSSA SANDOSTATIN LAR DEPOT OCTREOTIDE
Octreotide hydrochloride	Oczyesa

[1] SSTR2 💬

[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬

[8] 67, 75, 77, 84, 85, 89, 193, 227 💬

Disease ID	Name
67	Polycystic kidney disease
75	Cushing disease
77	Growth hormone secreting pituitary adenoma
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
89	Lymphangioleiomyomatosis
193	Prader-Willi syndrome
227	Osler disease

Oxygen

[1] Oxygen

[1] Oxygen 💬

[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
19	Lysosomal storage disease
22	Moyamoya disease
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
70	Spinal stenosis
71	Idiopathic osteonecrosis of the femoral head
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
90	Retinitis pigmentosa
96	Crohn disease
97	Ulcerative colitis
129	Acute encephalopathy with biphasic seizures and late reduced diffusion
149	Hemiconvulsion hemiplegia epilepsy syndrome
168	Ehlers-Danlos syndrome
193	Prader-Willi syndrome
211	Hypoplastic left heart syndrome
226	Interstitial cystitis with Hunners ulcer
230	Alveolar hypoventilation syndrome
235	Hypoparathyroidism
269	Pyogenic arthritis
271	Ankylosing spondylitis
294	Congenital diaphragmatic hernia
298	Hereditary pancreatitis
299	Cystic fibrosis
330	Congenital tracheal stenosis

Oxytocin

[1] Oxytocin

[1] Oxytocin 💬

[1] OXTR 💬

[5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬

[8] 6, 70, 72, 127, 168, 193, 206, 226 💬

Disease ID	Name
6	Parkinson disease
70	Spinal stenosis
72	Pituitary ADH secretion disorder
127	Frontotemporal lobar degeneration
168	Ehlers-Danlos syndrome
193	Prader-Willi syndrome
206	Fragile X syndrome
226	Interstitial cystitis with Hunners ulcer

Pitolisant

[1] Pitolisant

[2] Pitolisant ,
Pitolisant hydrochloride 💬

[1] HRH3 💬

[2] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬

[3] 6, 113, 193 💬

Rimonabant

[1] Rimonabant

[1] Rimonabant 💬

[1] CNR1 💬

[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬

[1] 193 💬

Setmelanotide

[1] Setmelanotide

[2] Setmelanotide ,
Setmelanotide acetate 💬

[1] MC4R 💬

[3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬

[5] 134, 193, 202, 236, 265 💬

Sodium chloride

[3] NaCl; Sodium chloride; Sodium chloride solution

[1] Sodium chloride 💬

[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
22	Moyamoya disease
34	Neurofibromatosis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
65	Primary immunodeficiency
67	Polycystic kidney disease
70	Spinal stenosis
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
168	Ehlers-Danlos syndrome
193	Prader-Willi syndrome
214	Pulmonary atresia with ventricular septum defect
215	Tetralogy of Fallot
226	Interstitial cystitis with Hunners ulcer
227	Osler disease
228	Bronchiolitis obliterans
271	Ankylosing spondylitis
288	Autoimmune acquired coagulation factor deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis

Tesofensine

[2] TESOFENSINE; TESOFENSINE CITRATE

[2] 6, 193 💬

Tirzepatide

[1] Tirzepatide

[1] Tirzepatide 💬

[2] GIPR,
GLP1R 💬

[4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬

[6] 67, 96, 97, 193, 233, 265 💬

Topiramate

[1] Topiramate

[1] Topiramate 💬

[37] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
CA2	carbonic anhydrase 2 isoform 1
CA4	carbonic anhydrase 4 preproprotein
CACNA1C	voltage-dependent L-type calcium channel subunit alpha-1C isoform 18
CACNA1D	voltage-dependent L-type calcium channel subunit alpha-1D isoform b
CACNA1F	voltage-dependent L-type calcium channel subunit alpha-1F isoform 1
CACNA1S	voltage-dependent L-type calcium channel subunit alpha-1S
GABRA1	gamma-aminobutyric acid receptor subunit alpha-1 precursor
GABRA2	gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor
GABRA3	gamma-aminobutyric acid receptor subunit alpha-3 precursor
GABRA4	gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor
GABRA5	gamma-aminobutyric acid receptor subunit alpha-5 precursor
GABRA6	gamma-aminobutyric acid receptor subunit alpha-6 precursor
GABRB1	gamma-aminobutyric acid receptor subunit beta-1 precursor
GABRB2	gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor
GABRB3	gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor
GABRD	gamma-aminobutyric acid receptor subunit delta precursor
GABRE	gamma-aminobutyric acid receptor subunit epsilon precursor
GABRG1	gamma-aminobutyric acid receptor subunit gamma-1 precursor
GABRG2	gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor
GABRG3	gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor
GABRP	gamma-aminobutyric acid receptor subunit pi isoform 1 precursor
GABRQ	gamma-aminobutyric acid receptor subunit theta precursor
GRIA1	glutamate receptor 1 isoform 1 precursor
GRIA2	glutamate receptor 2 isoform 1 precursor
GRIA3	glutamate receptor 3 isoform 2 precursor
GRIA4	glutamate receptor 4 isoform 1 precursor
GRIK1	glutamate receptor ionotropic, kainate 1 isoform 1 precursor
GRIK2	glutamate receptor ionotropic, kainate 2 isoform 1 precursor
GRIK3	glutamate receptor ionotropic, kainate 3 precursor
GRIK4	glutamate receptor ionotropic, kainate 4 isoform 1 precursor
GRIK5	glutamate receptor ionotropic, kainate 5 isoform 2 precursor
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[55] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Cadherin signaling, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, IgSF CAM signaling, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[6] 6, 97, 140, 144, 156, 193 💬