Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Alemtuzumab 💬[1] Alemtuzumab[1] Alemtuzumab--[18] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
2 Bezafibrate 💬[1] Bezafibrate[1] Bezafibrate[1] NR1C1 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[8] 20, 93, 94, 160, 296, 316, 324, 344 💬
3 Busulfan 💬[1] Busulfan[2] Busulfan; Busulfano--[14] 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
4 Chenodiol 💬[1] Chenodeoxycholic acid[2] Chenodeoxycholic acid; Chenodiol[1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 96, 234, 263 💬
5 Cholecalciferol 💬[1] Cholecalciferol[4] Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[15] 6, 13, 19, 20, 34, 46, 49, 51, 53, 65, 96, 97, 228, 298, 299 💬
6 Cholic acid 💬[1] Cholic Acid[1] Cholic acid[1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 234, 265, 310 💬
7 Clofarabine 💬[1] Clofarabine[1] Clofarabine[3] POLA1,
POLA2,
RRM1 💬 		[5] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 96, 234 💬
8 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--[46] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
9 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--[46] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
10 Cyclosporine 💬[1] Cyclosporine[6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
11 Dimethyl fumarate 💬[1] Dimethyl fumarate[2] Dimethyl fumarate; Dimethylfumarat[1] KLHL19 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[6] 13, 20, 49, 51, 86, 296 💬
12 Elivaldogene autotemcel 💬[1] Elivaldogene autotemcel[1] Elivaldogene autotemcel[1] ABCD1 💬 [2] ABC transporters, Peroxisome 💬[1] 20 💬
13 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
14 Interferon beta 💬[1] Human interferon beta[3] Human interferon beta; Interferon beta; Interferon-beta[2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[3] 13, 20, 50 💬
15 Leriglitazone 💬[1] Leriglitazone[1] Leriglitazone[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 20 💬
16 Melphalan 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
17 Melphalan hydrochloride 💬[1] Melphalan[2] Melphalan; Melphalan hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
18 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
19 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
20 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
21 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[12] 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
22 Pioglitazone 💬[1] Pioglitazone[1] Pioglitazone[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[16] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 220, 229, 265, 298, 299 💬
23 Pioglitazone hydrochloride 💬[1] Pioglitazone[1] Pioglitazone[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[16] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 220, 229, 265, 298, 299 💬
24 Plerixafor 💬[1] Plerixafor[1] Plerixafor[1] CXCR4 💬 [14] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[4] 20, 51, 65, 285 💬
25 Pramipexole 💬[1] Pramipexole[3] Pramipexol; Pramipexole; Pramipexole dihydrochloride monohydrate[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 20 💬
26 Pramipexole dihydrochloride 💬[1] Pramipexole[3] Pramipexol; Pramipexole; Pramipexole dihydrochloride monohydrate[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 20 💬
27 Sobetirome 💬[1] Sobetirome[1] Sobetirome[1] THRB 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 20 💬
28 Thalidomide 💬[1] Thalidomide[1] Thalidomide[1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300 💬
29 Thioctic acid 💬[1] Lipoic acid[1] Lipoic acid--[3] 13, 14, 20 💬
30 Thiotepa 💬[1] Thiotepa[1] Thiotepa--[11] 13, 28, 46, 51, 60, 65, 85, 96, 107, 284, 285 💬
31 Ursodiol 💬[1] Ursodeoxycholic acid[3] Udca; Ursodeoxycholic acid; Ursodiol[1] NR1H4 💬 [1] Bile secretion 💬[13] 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
32 Vitamin E 💬[1] Vitamin E[2] Alpha-tocopherol; Vitamin E--[6] 2, 19, 20, 49, 90, 206 💬