Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetylcysteine [4] Acetylcysteine; N acetyl cysteine; N-Acetyl cysteine; N-Acetylcysteine[1] Acetylcysteine 💬 --[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
2 Alemtuzumab [1] Alemtuzumab[1] Alemtuzumab 💬 --[21] 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
3 Bezafibrate [1] BEZAFIBRATE[1] Bezafibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[8] 20, 93, 94, 160, 296, 316, 324, 344 💬
4 Biotin [4] Biotin; Biotina; D-BIOTIN; Vitamin B7[1] Biotin 💬 --[6] 2, 8, 10, 13, 14, 20 💬
5 Busulfan [2] Busulfan; BUSULFANO[1] Busulfan 💬 --[14] 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
6 Chenodeoxycholic acid [2] Chenodeoxycholic Acid; Chenodiol[1] Chenodiol 💬 [1] NR1H4 💬 [1] Bile secretion 💬[5] 20, 86, 96, 234, 263 💬
7 Cholic Acid [1] Cholic Acid[1] Cholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 234, 265, 310 💬
8 Clofarabine [1] Clofarabine[1] Clofarabine 💬 [3] POLA1,
POLA2,
RRM1 💬 		[5] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
9 Cyclophosphamide [5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
10 Cyclosporine [7] CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
11 Dimethyl fumarate [1] DIMETHYL FUMARATE[1] Dimethyl fumarate 💬 [1] KEAP1 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 20, 51, 86, 296 💬
12 Elivaldogene autotemcel [1] Elivaldogene autotemcel[1] Elivaldogene autotemcel 💬 [1] ABCD1 💬 [2] ABC transporters, Peroxisome 💬[1] 20 💬
13 Glyceryl Trierucate [1] Glyceryl Trierucate---[1] 20 💬
14 Glyceryl Trioleate [1] Glyceryl Trioleate---[1] 20 💬
15 Hydroxyurea [1] Hydroxyurea[1] Hydroxyurea 💬 [1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
16 Leriglitazone [1] Leriglitazone[1] Leriglitazone 💬 [1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 20 💬
17 Lipoic acid [3] Alpha Lipoic Acid; Alpha-lipoic acid; Lipoic acid[1] Thioctic acid 💬 --[6] 2, 5, 13, 14, 20, 97 💬
18 Melphalan [2] Melphalan; Melphalan Hydrochloride[2] Melphalan ,
Melphalan hydrochloride 💬 		--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
19 Mycophenolate mofetil [1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
20 Pioglitazone [1] Pioglitazone[2] Pioglitazone hydrochloride ,
Pioglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
21 Plerixafor [1] PLERIXAFOR[1] Plerixafor 💬 [1] CXCR4 💬 [14] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[5] 20, 51, 65, 285, 299 💬
22 Pramipexole [3] Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE[2] Pramipexole dihydrochloride ,
Pramipexole 💬 		[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 20, 74 💬
23 PXL-770 free acid anhydrous [0] ---[1] 20 💬
24 SBT101 [1] SBT101---[1] 20 💬
25 Sobetirome [1] Sobetirome[1] Sobetirome 💬 [1] THRB 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 20 💬
26 Thalidomide [1] Thalidomide[1] Thalidomide 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
27 Thiotepa [1] Thiotepa[1] Thiotepa 💬 --[14] 13, 19, 20, 28, 46, 51, 60, 65, 85, 96, 107, 164, 284, 285 💬
28 Vitamin E [1] Vitamin E[1] Vitamin E 💬 --[12] 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
29 VK-0214 [1] VK0214---[1] 20 💬