Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir 💬[1] Abacavir[2] Abacavir; Abacavir sulfate--[5] 2, 49, 135, 265, 325 💬
2 Abacavir sulfate 💬[1] Abacavir[2] Abacavir; Abacavir sulfate--[5] 2, 49, 135, 265, 325 💬
3 Acipimox 💬[1] Acipimox[1] Acipimox--[2] 78, 265 💬
4 Amprenavir 💬[1] Amprenavir[1] Amprenavir--[1] 265 💬
5 Atazanavir 💬[1] Atazanavir[1] Atazanavir--[1] 265 💬
6 Atazanavir sulfate 💬[1] Atazanavir[1] Atazanavir--[1] 265 💬
7 Atorvastatin 💬[1] Atorvastatin[3] Atorvastatin; Atorvastatin Calcium; Atorvastatina[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
8 Atorvastatin calcium 💬[1] Atorvastatin[3] Atorvastatin; Atorvastatin Calcium; Atorvastatina[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
9 Baricitinib 💬[1] Baricitinib[1] Baricitinib[2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[24] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
10 Caffeine 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
11 Caffeine citrate 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
12 Cholic acid 💬[1] Cholic Acid[1] Cholic Acid[1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 234, 265, 310 💬
13 Coptis rhizome 💬[1] Berberine[2] Berberine; Berberine Chloride--[3] 46, 97, 265 💬
14 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
15 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
16 Didanosine 💬[1] Didanosine[1] Didanosine--[2] 25, 265 💬
17 Diosmin 💬[1] Diosmin[1] Diosmin--[4] 46, 51, 97, 265 💬
18 Dolutegravir 💬[1] Dolutegravir[1] Dolutegravir--[3] 2, 26, 265 💬
19 Dolutegravir sodium 💬[1] Dolutegravir[1] Dolutegravir--[3] 2, 26, 265 💬
20 Doravirine 💬[1] Doravirine[1] Doravirine--[1] 265 💬
21 Efavirenz 💬[1] Efavirenz[1] Efavirenz--[3] 23, 67, 265 💬
22 Emtricitabine 💬[1] Emtricitabine[1] Emtricitabine--[5] 13, 25, 93, 265, 325 💬
23 Enfuvirtide 💬[1] Enfuvirtide[1] Enfuvirtide--[2] 25, 265 💬
24 Fenofibrate 💬[1] Fenofibrate[1] Fenofibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
25 Indinavir 💬[1] Indinavir[1] Indinavir--[1] 265 💬
26 Indinavir sulfate 💬[1] Indinavir[1] Indinavir--[1] 265 💬
27 Indinavir sulfate ethanolate 💬[1] Indinavir[1] Indinavir--[1] 265 💬
28 Lactic acid 💬[1] Lactic acid[1] Lactic acid--[3] 46, 265, 299 💬
29 Lamivudine 💬[1] Lamivudine[1] Lamivudine--[10] 2, 26, 42, 46, 49, 135, 156, 223, 265, 325 💬
30 Lopinavir 💬[1] Lopinavir[1] Lopinavir--[1] 265 💬
31 Mecasermin 💬[1] Mecasermin[1] MECASERMIN[2] GHR,
IGF1R 💬 		[34] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cadherin signaling, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Hormone signaling, Integrin signaling, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[4] 96, 168, 265, 299 💬
32 Mecasermin rinfabate 💬[1] Mecasermin[1] Mecasermin[2] GHR,
IGF1R 💬 		[34] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cadherin signaling, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Hormone signaling, Integrin signaling, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[4] 96, 168, 265, 299 💬
33 Melatonin 💬[1] Melatonin[1] Melatonin[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
34 Metformin 💬[1] Metformin[4] Metformin; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
35 Metformin hydrochloride 💬[1] Metformin[4] Metformin; Metformin hydrochloride; METFORMINA; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
36 Metreleptin 💬[1] Metreleptin[2] METRELEPTIN; R-metHuLeptin[1] LEPR 💬 [7] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265 💬
37 Nelfinavir 💬[1] Nelfinavir[2] Nelfinavir; Nelfinavir mesylate--[3] 49, 265, 331 💬
38 Nelfinavir mesylate 💬[1] Nelfinavir[2] Nelfinavir; Nelfinavir mesylate--[3] 49, 265, 331 💬
39 Nevirapine 💬[1] Nevirapine[1] Nevirapine--[1] 265 💬
40 Niacin 💬[1] Niacin[2] Niacin; Nicotinic acid--[4] 6, 46, 79, 265 💬
41 Obeticholic acid 💬[1] Obeticholic acid[1] Obeticholic Acid[1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
42 Pegvisomant 💬[1] Pegvisomant[1] Pegvisomant[1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 77, 265 💬
43 Pioglitazone 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
44 Pioglitazone hydrochloride 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
45 Pravastatin 💬[1] Pravastatin[2] Pravastatin; Pravastatin sodium[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
46 Pravastatin sodium 💬[1] Pravastatin[2] Pravastatin; Pravastatin sodium[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
47 Raltegravir 💬[1] Raltegravir[1] Raltegravir--[4] 13, 26, 93, 265 💬
48 Raltegravir potassium 💬[1] Raltegravir[1] Raltegravir--[4] 13, 26, 93, 265 💬
49 Riboflavin 💬[1] Riboflavin[2] RIBOFLAVIN; Vitamin B2--[8] 13, 38, 46, 96, 97, 162, 168, 265 💬
50 Ritonavir 💬[1] Ritonavir[1] Ritonavir--[3] 2, 86, 265 💬
51 Rosiglitazone 💬[1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[7] 46, 57, 75, 77, 97, 222, 265 💬
52 Rosiglitazone maleate 💬[1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[7] 46, 57, 75, 77, 97, 222, 265 💬
53 Saquinavir 💬[1] Saquinavir[1] Saquinavir--[4] 86, 222, 223, 265 💬
54 Saquinavir mesylate 💬[1] Saquinavir[1] Saquinavir--[4] 86, 222, 223, 265 💬
55 Setmelanotide 💬[1] Setmelanotide[1] Setmelanotide[1] MC4R 💬 [3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 134, 193, 202, 236, 265 💬
56 Setmelanotide acetate 💬[1] Setmelanotide[1] Setmelanotide[1] MC4R 💬 [3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 134, 193, 202, 236, 265 💬
57 Simvastatin 💬[1] Simvastatin[2] Simvastatin; Simvastatine[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
58 Sodium lactate 💬[1] Lactic acid[1] Lactic acid--[3] 46, 265, 299 💬
59 Stavudine 💬[1] Stavudine[1] Stavudine--[1] 265 💬
60 Tenofovir 💬[1] Tenofovir[1] Tenofovir--[8] 2, 6, 13, 25, 26, 93, 265, 325 💬
61 Tenofovir disoproxil fumarate 💬[1] Tenofovir disoproxil[2] Tenofovir disoproxil; Tenofovir Disoproxil Fumarate--[3] 6, 93, 265 💬
62 Tenofovir disoproxil maleate 💬[1] Tenofovir disoproxil[2] Tenofovir disoproxil; Tenofovir Disoproxil Fumarate--[3] 6, 93, 265 💬
63 Tenofovir disoproxil phosphate 💬[1] Tenofovir disoproxil[2] Tenofovir disoproxil; Tenofovir Disoproxil Fumarate--[3] 6, 93, 265 💬
64 Tesamorelin 💬[1] Tesamorelin[1] Tesamorelin[1] GHRHR 💬 [3] Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬[1] 265 💬
65 Tesamorelin acetate 💬[1] Tesamorelin[1] Tesamorelin[1] GHRHR 💬 [3] Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction 💬[1] 265 💬
66 Testosterone 💬[1] Testosterone[1] Testosterone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
67 Thiamine 💬[1] Thiamine[1] THIAMINE--[5] 8, 13, 93, 265, 340 💬
68 Thiamine hydrochloride 💬[1] Thiamine[1] Thiamine--[5] 8, 13, 93, 265, 340 💬
69 Thiamine mononitrate 💬[1] Thiamine[1] Thiamine--[5] 8, 13, 93, 265, 340 💬
70 Tipranavir 💬[1] Tipranavir[1] Tipranavir--[1] 265 💬
71 Tipranavir disodium 💬[1] Tipranavir[1] Tipranavir--[1] 265 💬
72 Tirzepatide 💬[1] Tirzepatide[1] Tirzepatide[2] GIPR,
GLP1R 💬 		[4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 67, 96, 97, 193, 233, 265 💬
73 Volanesorsen 💬[1] Volanesorsen[1] Volanesorsen[1] APOC3 💬 [2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265 💬
74 Volanesorsen sodium 💬[1] Volanesorsen[1] Volanesorsen[1] APOC3 💬 [2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265 💬
75 Zidovudine 💬[1] Zidovudine[1] Zidovudine--[6] 25, 26, 135, 265, 325, 331 💬