Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Amifampridine 💬[1] Amifampridine[2] Amifampridine; Amifampridine Phosphate[7] KCNA1,
KCNA2,
KCNA4,
KCNA6,
KCNC3,
KCND2,
KCND3 💬 		[5] Cortisol synthesis and secretion, Cushing syndrome, IgSF CAM signaling, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12 💬
2 Amifampridine phosphate 💬[1] Amifampridine[2] Amifampridine; Amifampridine Phosphate[7] KCNA1,
KCNA2,
KCNA4,
KCNA6,
KCNC3,
KCND2,
KCND3 💬 		[5] Cortisol synthesis and secretion, Cushing syndrome, IgSF CAM signaling, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12 💬
3 Apitegromab 💬[1] Apitegromab[1] Apitegromab[1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[2] 3, 113 💬
4 Branaplam 💬[1] Branaplam[1] Branaplam--[2] 3, 8 💬
5 Celecoxib 💬[1] Celecoxib[1] Celecoxib[1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
6 Divalproex sodium 💬[1] Valproic acid[3] Divalproex sodium; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
7 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
8 Itraconazole 💬[1] Itraconazole[1] Itraconazole--[13] 2, 3, 6, 46, 65, 67, 96, 97, 137, 158, 227, 299, 309 💬
9 Leuprolide 💬[1] Leuprolide[2] Leuprolide; Leuprorelin[1] GNRHR 💬 [3] GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬[5] 1, 2, 3, 51, 76 💬
10 Leuprolide acetate 💬[1] Leuprolide[2] Leuprolide; Leuprorelin[1] GNRHR 💬 [3] GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬[5] 1, 2, 3, 51, 76 💬
11 Leuprolide mesylate 💬[1] Leuprolide[2] Leuprolide; Leuprorelin[1] GNRHR 💬 [3] GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬[5] 1, 2, 3, 51, 76 💬
12 Levocarnitine 💬[1] Levocarnitine[1] Levocarnitine--[3] 3, 53, 97 💬
13 Levocarnitine chloride 💬[1] Levocarnitine[1] Levocarnitine--[3] 3, 53, 97 💬
14 Midazolam 💬[1] Midazolam[1] Midazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
15 Midazolam hydrochloride 💬[1] Midazolam[1] Midazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
16 Midazolam maleate 💬[1] Midazolam[1] Midazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
17 Nusinersen 💬[1] Nusinersen[2] NUSINERSEN; NUSINERSEN SODIUM--[1] 3 💬
18 Nusinersen sodium 💬[1] Nusinersen[2] NUSINERSEN; NUSINERSEN SODIUM--[1] 3 💬
19 Olesoxime 💬[1] Olesoxime[1] Olesoxime--[3] 2, 3, 13 💬
20 Onasemnogene abeparvovec 💬[1] Onasemnogene abeparvovec[3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-brve; Onasemnogene Abeparvovec-xioi--[1] 3 💬
21 Prednisolone 💬[1] Prednisolone[3] Prednisolona; Prednisolone; Prednisolonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
22 Prednisolone sodium phosphate 💬[1] Prednisolone phosphate[1] PREDNISOLONE SODIUM PHOSPHATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 3, 13, 97 💬
23 Propofol 💬[1] Propofol[1] Propofol[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
24 Pyridostigmine bromide 💬[1] Pyridostigmine[2] Pyridostigmine; PYRIDOSTIGMINE BROMIDE[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[5] 3, 6, 11, 51, 256 💬
25 Reldesemtiv 💬[1] Reldesemtiv[2] CK-2127107; Reldesemtiv[3] TNNC2,
TNNI2,
TNNT3 💬 		[3] Calcium signaling pathway, Cytoskeleton in muscle cells, Motor proteins 💬[2] 2, 3 💬
26 Riluzole 💬[1] Riluzole[1] Riluzole[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
27 Risdiplam 💬[1] Risdiplam[1] Risdiplam--[1] 3 💬
28 Sesame oil 💬[1] Sesame oil[1] Sesame oil--[1] 3 💬
29 Sodium phenylbutyrate 💬[1] Phenylbutyric acid[2] PHENYLBUTYRATE; Sodium Phenylbutyrate--[5] 2, 3, 8, 18, 251 💬
30 Somatropin 💬[1] Somatotropin[2] Somatotropin; Somatropin[1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[3] 3, 65, 236 💬
31 Testosterone 💬[1] Testosterone[1] Testosterone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
32 Valproate sodium 💬[1] Valproic acid[3] Divalproex sodium; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
33 Valproic acid 💬[1] Valproic acid[3] Divalproex sodium; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
34 Water 💬[1] Water[1] Water--[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬