Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen 💬[1] Acetaminophen[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Albuterol 💬[1] Salbutamol[3] Albuterol; Salbutamol; Ventolin[1] ADRB2 💬 [9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
3 Amifampridine 💬[1] Amifampridine[2] Amifampridine; Firdapse[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12 💬
4 Apitegromab 💬[1] Apitegromab[1] Apitegromab[1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 3 💬
5 Branaplam 💬[1] Branaplam[1] BRANAPLAM[1] SMN2 💬 [1] 💬[2] 3, 8 💬
6 Celecoxib 💬[1] Celecoxib[2] CELEBREX; CELECOXIB[1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
7 Dalfampridine 💬[1] Dalfampridine[7] 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; FAMPYRA[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14 💬
8 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284 💬
9 Itraconazole 💬[1] Itraconazole[2] Itraconazole; SPORANOX--[6] 3, 46, 65, 96, 227, 299 💬
10 Levocarnitine 💬[1] Levocarnitine[4] Carnitine; L-Carnitine; LEVOCARNITINE; Xyzal--[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
11 Midazolam 💬[1] Midazolam[2] Midazolam; Midazolam injection[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
12 Nusinersen 💬[1] Nusinersen[2] NUSINERSEN; Spinraza[1] SMN2 💬 [1] 💬[1] 3 💬
13 Olesoxime 💬[1] Olesoxime[1] OLESOXIME--[3] 2, 3, 13 💬
14 Onasemnogene abeparvovec 💬[1] Onasemnogene abeparvovec[3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma[1] SMN1 💬 [1] 💬[1] 3 💬
15 Prednisolone 💬[1] Prednisolone[3] Prednisolona; PREDNISOLONE; Prednisolonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
16 Reldesemtiv 💬[1] Reldesemtiv[2] CK-2127107; RELDESEMTIV[1] TNNC2 💬 [1] Calcium signaling pathway 💬[2] 2, 3 💬
17 Riluzole 💬[1] Riluzole[2] Rilutek; Riluzole[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
18 Risdiplam 💬[1] Risdiplam[2] EVRYSDI; Risdiplam[1] SMN2 💬 [1] Nucleocytoplasmic transport 💬[1] 3 💬
19 Sesame oil 💬[1] Sesame oil[1] Sesame oil--[1] 3 💬
20 Taldefgrobep alfa 💬[1] Talditercept alfa[1] Taldefgrobep alfa[1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 3 💬
21 Testosterone 💬[1] Testosterone[1] Testosterone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[8] 1, 2, 3, 13, 60, 76, 78, 113 💬
22 Valproic acid 💬[1] Valproic acid[3] Valproate; VALPROATE SODIUM; Valproic Acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬