Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen [2] Acetaminophen; Paracetamol[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 Albuterol [2] Albuterol; Salbutamol[2] Albuterol sulfate ,
Albuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[16] 2, 3, 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
3 Amifampridine [2] Amifampridine; Amifampridine phosphate[2] Amifampridine ,
Amifampridine phosphate 💬 		[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12 💬
4 Apitegromab [1] Apitegromab[1] Apitegromab 💬 [1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 3 💬
5 BIIB115 [1] BIIB115---[1] 3 💬
6 Branaplam [1] Branaplam[1] Branaplam 💬 --[2] 3, 8 💬
7 Celecoxib [1] Celecoxib[1] Celecoxib 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
8 Dalfampridine [5] 4-aminopyridine; 4-AP; Dalfampridine; Fampridina; Fampridine[1] Dalfampridine 💬 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[4] 3, 4, 13, 14 💬
9 GYM329 [1] GYM329---[2] 3, 113 💬
10 Hydroxyurea [1] Hydroxyurea[1] Hydroxyurea 💬 [1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
11 Itraconazole [1] Itraconazole[1] Itraconazole 💬 --[8] 2, 3, 46, 65, 96, 97, 227, 299 💬
12 Leuprolide [2] Leuprolide; Leuprorelin[3] Leuprolide acetate ,
Leuprorelin ,
Leuprolide mesylate 💬 		[1] GNRHR 💬 [3] GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬[5] 1, 2, 3, 67, 76 💬
13 Levocarnitine [3] Carnitine; L-carnitine; Levocarnitine[2] Levocarnitine chloride ,
Levocarnitine 💬 		--[11] 2, 3, 13, 46, 53, 58, 86, 96, 97, 240, 265 💬
14 Midazolam [1] Midazolam[3] Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		[16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
15 Nerve Growth Factor [1] Nerve growth factor---[4] 2, 3, 53, 90 💬
16 Nusinersen [2] Nusinersen; Nusinersen sodium[2] Nusinersen sodium ,
Nusinersen 💬 		--[1] 3 💬
17 Olesoxime [1] Olesoxime[1] Olesoxime 💬 --[3] 2, 3, 13 💬
18 Onasemnogene abeparvovec [1] Onasemnogene abeparvovec[1] Onasemnogene abeparvovec 💬 --[1] 3 💬
19 Phenylbutyric acid [2] Phenylbutyrate; Sodium phenylbutyrate[1] Sodium phenylbutyrate 💬 --[10] 2, 3, 8, 15, 93, 94, 244, 251, 297, 338 💬
20 Phosphate ion [1] Phosphate---[13] 3, 13, 46, 49, 65, 70, 75, 90, 235, 238, 256, 286, 288 💬
21 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[41] 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
22 Propofol [1] Propofol[1] Propofol 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
23 Pyridostigmine [2] Pyridostigmine; Pyridostigmine bromide[1] Pyridostigmine bromide 💬 [1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[5] 3, 6, 11, 51, 256 💬
24 Reldesemtiv [2] CK-2127107; Reldesemtiv[1] Reldesemtiv 💬 [3] TNNC2,
TNNI2,
TNNT3 💬 		[3] Calcium signaling pathway, Cytoskeleton in muscle cells, Motor proteins 💬[2] 2, 3 💬
25 Riluzole [1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[8] 2, 3, 5, 8, 13, 17, 203, 206 💬
26 Risdiplam [1] Risdiplam[1] Risdiplam 💬 --[1] 3 💬
27 Sesame oil [0] [1] Sesame oil 💬 --[1] 3 💬
28 Somatotropin [7] Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina[1] Somatropin 💬 [1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[28] 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
29 Sulfate ion [1] Sulfate[1] Sulfuric acid 💬 --[8] 2, 3, 11, 49, 53, 64, 222, 224 💬
30 Talditercept alfa [1] Taldefgrobep alfa[1] Taldefgrobep alfa 💬 [1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 3 💬
31 Testosterone [1] Testosterone[1] Testosterone 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
32 Valproic acid [3] Valproate; Valproate sodium; Valproic acid[3] Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬