Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen 💬[1] Acetaminophen[2] Acetaminophen; Paracetamol[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[17] 3, 6, 11, 13, 19, 34, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 Cabergoline 💬[1] Cabergoline[2] Cabergolina; Cabergoline[2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 74, 75, 77 💬
3 Clomifene 💬[1] Clomifene[0] [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬-
4 Clomiphene citrate 💬[1] Clomifene[0] [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬-
5 Denosumab 💬[1] Denosumab[1] Denosumab[1] TNFSF11 💬 [8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[10] 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
6 Dextrose 💬[1] Dextrose, unspecified form[2] Dextrose; Glucose--[12] 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
7 Dopamine 💬[1] Dopamine[1] Dopamine[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 7, 77 💬
8 Dopamine hydrochloride 💬[1] Dopamine[1] Dopamine[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 7, 77 💬
9 Empagliflozin 💬[1] Empagliflozin[1] Empagliflozin--[10] 65, 67, 72, 77, 86, 96, 97, 257, 298, 299 💬
10 Escitalopram 💬[1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
11 Escitalopram oxalate 💬[1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
12 Furosemide 💬[1] Furosemide[1] Furosemide[1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 77, 86 💬
13 Glucose, liquid 💬[1] Dextrose, unspecified form[2] Dextrose; Glucose--[12] 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
14 Lanreotide acetate 💬[1] Lanreotide[2] Lanreotide; Lanreotide acetate[2] SSTR2,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 67, 73, 77, 85, 298 💬
15 Liraglutide 💬[1] Liraglutide[1] Liraglutide[1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 6, 13, 75, 77, 193 💬
16 Metformin 💬[1] Metformin[3] Metformin; Metformin hydrochloride; Metformina[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[27] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
17 Metformin hydrochloride 💬[1] Metformin[3] Metformin; Metformin hydrochloride; Metformina[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[27] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
18 Octreotide 💬[1] Octreotide[3] Octreotida; Octreotide; Octreotide acetate[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
19 Octreotide acetate 💬[1] Octreotide[3] Octreotida; Octreotide; Octreotide acetate[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
20 Octreotide acetate 💬[1] Octreotide[3] Octreotida; Octreotide; Octreotide acetate[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
21 Octreotide pamoate 💬[1] Octreotide[3] Octreotida; Octreotide; Octreotide acetate[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
22 Paltusotine 💬[1] Paltusotine[1] Paltusotine[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 77 💬
23 Pasireotide 💬[1] Pasireotide[4] Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 74, 75, 77 💬
24 Pasireotide diaspartate 💬[1] Pasireotide[4] Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 74, 75, 77 💬
25 Pasireotide pamoate 💬[1] Pasireotide[4] Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 74, 75, 77 💬
26 Pegvisomant 💬[1] Pegvisomant[1] Pegvisomant[1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 77, 265 💬
27 Phenylalanine 💬[1] Phenylalanine[1] Phenylalanine--[1] 240 💬
28 Raloxifene 💬[1] Raloxifene[2] Raloxifene; Raloxifene hydrochloride[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 46, 77 💬
29 Raloxifene hydrochloride 💬[1] Raloxifene[2] Raloxifene; Raloxifene hydrochloride[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 46, 77 💬
30 Rosiglitazone 💬[1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[6] 46, 75, 77, 97, 222, 265 💬
31 Rosiglitazone maleate 💬[1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[6] 46, 75, 77, 97, 222, 265 💬
32 Sitagliptin 💬[1] Sitagliptin[1] Sitagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[4] 6, 75, 77, 299 💬
33 Sitagliptin phosphate 💬[1] Sitagliptin[1] Sitagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[4] 6, 75, 77, 299 💬
34 Sitagliptin phosphate 💬[1] Sitagliptin[1] Sitagliptin[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[4] 6, 75, 77, 299 💬
35 Somatostatin 💬[1] Somatostatin[1] Somatostatin[5] SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 77 💬
36 Somatropin 💬[1] Somatotropin[7] Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina[1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[26] 2, 3, 19, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
37 Tadalafil 💬[1] Tadalafil[2] Tadalafil; Tadalafilo[1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 77, 84, 86, 113 💬
38 Tryptophan 💬[1] Tryptophan[2] Propanoic acid; Tryptophan--[2] 6, 46 💬
39 Tyrosine 💬[1] Tyrosine[3] Alanine; Propanoic acid; Tyrosine--[3] 6, 86, 298 💬
40 Zoledronate disodium 💬[1] Zoledronic acid[3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[14] 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
41 Zoledronate trisodium 💬[1] Zoledronic acid[3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[14] 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
42 Zoledronic acid 💬[1] Zoledronic acid[3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[14] 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
43 Zoledronic acid 💬[1] Zoledronic acid[3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[14] 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
44 Zoledronic acid hemipentahydrate 💬[1] Zoledronic acid[3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[14] 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬