Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen [2] Acetaminophen; Paracetamol[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 Cabergoline [2] Cabergolina; Cabergoline[1] Cabergoline 💬 [2] DRD2,
PRL 💬 		[14] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 74, 75, 77 💬
3 Clomifene [0] [2] Clomiphene citrate ,
Clomifene 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 74, 77 💬
4 Denosumab [1] Denosumab[1] Denosumab 💬 [1] TNFSF11 💬 [8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[10] 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
5 Dextrose, unspecified form [2] Dextrose; Glucose[2] Dextrose ,
Glucose, liquid 💬 		--[16] 6, 13, 50, 56, 60, 65, 66, 77, 96, 97, 168, 201, 226, 254, 257, 299 💬
6 Dopamine [1] Dopamine[2] Dopamine hydrochloride ,
Dopamine 💬 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 77 💬
7 Dopastatin [1] Dopastatin---[1] 77 💬
8 Empagliflozin [1] Empagliflozin[1] Empagliflozin 💬 --[13] 46, 58, 65, 67, 72, 77, 86, 96, 97, 113, 257, 298, 299 💬
9 Escitalopram [3] Citalopram; Escitalopram; Escitalopram oxalate[2] Escitalopram oxalate ,
Escitalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[5] 2, 6, 13, 46, 77 💬
10 Furosemide [1] Furosemide[1] Furosemide 💬 [1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[3] 6, 77, 86 💬
11 Gadolinium [1] Gadolinium---[7] 13, 34, 46, 65, 77, 86, 305 💬
12 Lanreotide [2] Lanreotide; Lanreotide acetate[1] Lanreotide acetate 💬 [2] SSTR2,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 67, 73, 77, 85, 298 💬
13 Liraglutide [1] Liraglutide[1] Liraglutide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 6, 13, 75, 77, 193 💬
14 Metformin [3] Metformin; Metformin hydrochloride; Metformina[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[28] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
15 Octreotide [3] Octreotida; Octreotide; Octreotide acetate[4] Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate 💬 		[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
16 Paltusotine [1] Paltusotine[1] Paltusotine 💬 [1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 77 💬
17 Pasireotide [4] Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate[3] Pasireotide ,
Pasireotide diaspartate ,
Pasireotide pamoate 💬 		[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[4] 67, 74, 75, 77 💬
18 Pegvisomant [1] Pegvisomant[1] Pegvisomant 💬 [1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 77, 265 💬
19 Phenylalanine [1] Phenylalanine[1] Phenylalanine 💬 --[3] 75, 77, 240 💬
20 Raloxifene [2] Raloxifene; Raloxifene hydrochloride[2] Raloxifene hydrochloride ,
Raloxifene 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 46, 77 💬
21 Rosiglitazone [2] Rosiglitazone; Rosiglitazone maleate[2] Rosiglitazone maleate ,
Rosiglitazone 💬 		[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[6] 46, 75, 77, 97, 222, 265 💬
22 Sitagliptin [1] Sitagliptin[3] Sitagliptin phosphate ,
Sitagliptin ,
Sitagliptin phosphate 💬 		[1] DPP4 💬 [2] Protein digestion and absorption, Virion - Hepatitis viruses 💬[5] 6, 75, 77, 233, 299 💬
23 Somatostatin [1] Somatostatin[1] Somatostatin 💬 [5] SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		[5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 77 💬
24 Somatotropin [7] Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina[1] Somatropin 💬 [1] GHR 💬 [6] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[28] 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
25 Tadalafil [2] Tadalafil; Tadalafilo[1] Tadalafil 💬 [1] PDE5 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[8] 6, 51, 75, 77, 84, 86, 113, 210 💬
26 Tryptophan [2] Propanoic acid; Tryptophan[1] Tryptophan 💬 --[4] 6, 46, 75, 77 💬
27 Tyrosine [3] Alanine; Propanoic acid; Tyrosine[1] Tyrosine 💬 --[5] 6, 75, 77, 86, 298 💬
28 Zoledronic acid [3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬