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Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Alcoholic liver disease 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Alcoholic liver disease 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Alcoholic liver disease 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Complement and coagulation cascades 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Complement and coagulation cascades 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Complement and coagulation cascades 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Complement and coagulation cascades 💬

[1] CFB 💬

Iptacopan 💬

Iptacopan

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
222	Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Complement and coagulation cascades 💬

[1] CFB 💬

Iptacopan hydrochloride 💬

Iptacopan

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
222	Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Coronavirus disease 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Coronavirus disease 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Coronavirus disease 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Coronavirus disease 💬

[1] CFB 💬

Iptacopan 💬

Iptacopan

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
222	Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Coronavirus disease 💬

[1] CFB 💬

Iptacopan hydrochloride 💬

Iptacopan

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
222	Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Herpes simplex virus 1 infection 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Neuroactive ligand-receptor interaction 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Neutrophil extracellular trap formation 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Pertussis 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Pertussis 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Pertussis 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Prion disease 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Prion disease 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Prion disease 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Regulation of actin cytoskeleton 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Regulation of actin cytoskeleton 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Regulation of actin cytoskeleton 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Staphylococcus aureus infection 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Staphylococcus aureus infection 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Staphylococcus aureus infection 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;

Staphylococcus aureus infection 💬

[1] CFB 💬

Iptacopan 💬

Iptacopan

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
222	Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Staphylococcus aureus infection 💬

[1] CFB 💬

Iptacopan hydrochloride 💬

Iptacopan

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
63	Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
222	Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Systemic lupus erythematosus 💬

[1] C5 💬

Crovalimab 💬

Crovalimab

[3] 48, 62, 109 💬

Disease ID	Name
48	Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;

Systemic lupus erythematosus 💬

[1] C5 💬

Eculizumab 💬

Eculizumab

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
14	Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy;
61	Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
221	Anti-glomerular basement membrane disease;Goodpasture syndrome;Glomerulonephritis;
223	Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN;

Systemic lupus erythematosus 💬

[1] C5 💬

Ravulizumab 💬

Ravulizumab

[8] 2 , 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis;
50	Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM;
62	Paroxysmal nocturnal hemoglobinuria;PNH;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;Glomerulonephritis;
109	Atypical hemolytic uremic syndrome;Atypical HUS;aHUS;
224	Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN;