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Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus

Eculizumab 💬

[8] 11, 13, 14, 61, 62, 109, 221, 223 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
109	Atypical hemolytic uremic syndrome
221	Anti-glomerular basement membrane disease
223	Primary membranoproliferative glomerulonephritis

2

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus

Crovalimab 💬

[3] 48, 62, 109 💬

3

[11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus

Ravulizumab 💬

[8] 2, 11, 13, 50, 62, 66, 109, 224 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
50	Dermatomyositis
62	Paroxysmal nocturnal hemoglobinuria
66	IgA nephropathy
109	Atypical hemolytic uremic syndrome
224	Purpura nephritis

4

[3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease

Iptacopan hydrochloride 💬

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
109	Atypical hemolytic uremic syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis

5

[3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease

[8] 11, 61, 62, 63, 66, 109, 222, 223 💬

Disease ID	Name
11	Myasthenia gravis
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
109	Atypical hemolytic uremic syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis