Gene

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Alcoholism 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;

Porphyria;Acute intermittent porphyria;AIP;Hereditary coproporphyria;HCP;Variegate porphyria;VP;Erythropoietic protoporphyria;EPP;Porphyria cutanea tarda;PCT;Congenital erythropoietic porphyria;CEP;X-linked dominant protoporphyria;XLDP;Hepatoerythropoietic porphyria;HEP;

Alcoholism 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Alzheimer disease 💬

[3] CHRM1, CHRM3, CHRM5 💬

[2] 120, 254 💬

Disease ID

Name

Alzheimer disease 💬

[3] CHRM1, CHRM3, CHRM5 💬

[2] 120, 254 💬

Disease ID

Name

Amphetamine addiction 💬

[1] DRD1 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Calcium signaling pathway 💬

[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM5	muscarinic acetylcholine receptor M5
HRH1	histamine H1 receptor
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Calcium signaling pathway 💬

[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM5	muscarinic acetylcholine receptor M5
HRH1	histamine H1 receptor
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Calcium signaling pathway 💬

[2] DRD1, DRD5 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

cAMP signaling pathway 💬

[3] CHRM1, CHRM2, DRD2 💬

[2] 120, 254 💬

Disease ID

Name

cAMP signaling pathway 💬

[3] CHRM1, CHRM2, DRD2 💬

[2] 120, 254 💬

Disease ID

Name

cAMP signaling pathway 💬

[3] DRD1, DRD2, DRD5 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

cGMP-PKG signaling pathway 💬

[3] ADRA2A, ADRA2B, ADRA2C 💬

[2] 120, 254 💬

Disease ID

Name

cGMP-PKG signaling pathway 💬

[3] ADRA2A, ADRA2B, ADRA2C 💬

[2] 120, 254 💬

Disease ID

Name

Cholinergic synapse 💬

[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬

Name	Full Name
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM4	muscarinic acetylcholine receptor M4
CHRM5	muscarinic acetylcholine receptor M5

[2] 120, 254 💬

Disease ID

Name

Cholinergic synapse 💬

[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬

Name	Full Name
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM4	muscarinic acetylcholine receptor M4
CHRM5	muscarinic acetylcholine receptor M5

[2] 120, 254 💬

Disease ID

Name

Cocaine addiction 💬

[2] DRD1, DRD2 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Cocaine addiction 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Cocaine addiction 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Dopaminergic synapse 💬

[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Dopaminergic synapse 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Dopaminergic synapse 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Gap junction 💬

[2] DRD1, DRD2 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Gap junction 💬

[4] DRD2, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
DRD2	D(2) dopamine receptor isoform long
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Gap junction 💬

[4] DRD2, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
DRD2	D(2) dopamine receptor isoform long
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Gastric acid secretion 💬

[1] CHRM3 💬

[2] 120, 254 💬

Disease ID

Name

Gastric acid secretion 💬

[1] CHRM3 💬

[2] 120, 254 💬

Disease ID

Name

Hormone signaling 💬

[4] ADRA2A, ADRA2B, ADRA2C, DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Hormone signaling 💬

[4] ADRA2A, ADRA2B, ADRA2C, DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Hormone signaling 💬

[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Inflammatory mediator regulation of TRP channels 💬

[4] HRH1, HTR2A, HTR2B, HTR2C 💬

[2] 120, 254 💬

Disease ID

Name

Inflammatory mediator regulation of TRP channels 💬

[4] HRH1, HTR2A, HTR2B, HTR2C 💬

[2] 120, 254 💬

Disease ID

Name

Insulin secretion 💬

[1] CHRM3 💬

[2] 120, 254 💬

Disease ID

Name

Insulin secretion 💬

[1] CHRM3 💬

[2] 120, 254 💬

Disease ID

Name

Morphine addiction 💬

[1] DRD1 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Neuroactive ligand signaling 💬

[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM4	muscarinic acetylcholine receptor M4
CHRM5	muscarinic acetylcholine receptor M5
DRD2	D(2) dopamine receptor isoform long
HRH1	histamine H1 receptor
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Neuroactive ligand signaling 💬

[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM4	muscarinic acetylcholine receptor M4
CHRM5	muscarinic acetylcholine receptor M5
DRD2	D(2) dopamine receptor isoform long
HRH1	histamine H1 receptor
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Neuroactive ligand signaling 💬

[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Neuroactive ligand-receptor interaction 💬

[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM4	muscarinic acetylcholine receptor M4
CHRM5	muscarinic acetylcholine receptor M5
DRD2	D(2) dopamine receptor isoform long
HRH1	histamine H1 receptor
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Neuroactive ligand-receptor interaction 💬

[13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
ADRA2A	alpha-2A adrenergic receptor
ADRA2B	alpha-2B adrenergic receptor
ADRA2C	alpha-2C adrenergic receptor
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM4	muscarinic acetylcholine receptor M4
CHRM5	muscarinic acetylcholine receptor M5
DRD2	D(2) dopamine receptor isoform long
HRH1	histamine H1 receptor
HTR2A	5-hydroxytryptamine receptor 2A isoform 1
HTR2B	5-hydroxytryptamine receptor 2B isoform 1
HTR2C	5-hydroxytryptamine receptor 2C isoform a precursor

[2] 120, 254 💬

Disease ID

Name

Neuroactive ligand-receptor interaction 💬

[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Pancreatic secretion 💬

[1] CHRM3 💬

[2] 120, 254 💬

Disease ID

Name

Pancreatic secretion 💬

[1] CHRM3 💬

[2] 120, 254 💬

Disease ID

Name

Parkinson disease 💬

[2] DRD1, DRD2 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Parkinson disease 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Parkinson disease 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Pathways of neurodegeneration - multiple diseases 💬

[3] CHRM1, CHRM3, CHRM5 💬

[2] 120, 254 💬

Disease ID

Name

Pathways of neurodegeneration - multiple diseases 💬

[3] CHRM1, CHRM3, CHRM5 💬

[2] 120, 254 💬

Disease ID

Name

PI3K-Akt signaling pathway 💬

[2] CHRM1, CHRM2 💬

[2] 120, 254 💬

Disease ID

Name

PI3K-Akt signaling pathway 💬

[2] CHRM1, CHRM2 💬

[2] 120, 254 💬

Disease ID

Name

Rap1 signaling pathway 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Rap1 signaling pathway 💬

[1] DRD2 💬

[2] 120, 254 💬

Disease ID

Name

Rap1 signaling pathway 💬

[1] DRD2 💬

Levodopa 💬

[8] 5 , 6 , 17, 90, 120, 140, 164, 201 💬

Disease ID	Name
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;
17	Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome;
90	Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy;
120	Hereditary dystonia;Primary dystonia;X-linked dystonia parkinsonism;Lubag;Segawa syndrome;SS;Dopa-responsive dystonia;DRD;Paroxysmal nonkinesigenic dyskinesia 1;PNKD1;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Paroxysmal choreoathetosis and episodic ataxia and spasticity;CSE;Episodic kinesigenic dyskinesia 1;EKD1;Myoclonus-dystonia syndrome;MDS;Rapid-onset dystonia-parkinsonism;RDP;Alternating hemiplegia of childhood;AHC;Cerebellar ataxia, areflexia, pes cavus, optic atropy, and sensorineural hearing loss;CAPOS;Paroxysmal execise-induced dyskinesia;PED;Episodic kinesigenic dyskinesia 2;EKD2;Paroxysmal nonkinesigenic dyskinesia 2;PNKD2;MEPAN syndrome;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;Hermansky-Pudlak syndrome;HPS;Chediak-Higashi syndrome;Chédiak-Higashi syndrome;CHS;Griscelli syndrome;
201	Angelman syndrome;

Regulation of actin cytoskeleton 💬

[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬

Name	Full Name
CHRM1	muscarinic acetylcholine receptor M1
CHRM2	muscarinic acetylcholine receptor M2
CHRM3	muscarinic acetylcholine receptor M3
CHRM4	muscarinic acetylcholine receptor M4
CHRM5	muscarinic acetylcholine receptor M5

[2] 120, 254 💬

Disease ID

Name