Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | ABC transporters 💬 4 genes, 14 drugs (DrugBank) and 10 diseases |
ABCC8 [1] ABCC8 💬ABC transporters
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Minoxidil Minoxidil 💬ABC transporters
| Minoxidil | 179 [1] 179 💬1. ABC transporters
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| 2 | Adrenergic signaling in cardiomyocytes 💬 31 genes, 86 drugs (DrugBank) and 81 diseases |
AGTR1 [1] AGTR1 💬Adrenergic signaling in cardiomyocytes
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Losartan potassium Losartan potassium 💬Adrenergic signaling in cardiomyocytes
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬2. Adrenergic signaling in cardiomyocytes
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| 3 | Adrenergic signaling in cardiomyocytes 💬 31 genes, 86 drugs (DrugBank) and 81 diseases |
AGTR1 [1] AGTR1 💬Adrenergic signaling in cardiomyocytes
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Losartan Losartan 💬Adrenergic signaling in cardiomyocytes
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬2. Adrenergic signaling in cardiomyocytes
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| 4 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 58 drugs (DrugBank) and 100 diseases |
AGTR1 [1] AGTR1 💬AGE-RAGE signaling pathway in diabetic complications
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Losartan potassium Losartan potassium 💬AGE-RAGE signaling pathway in diabetic complications
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬4. AGE-RAGE signaling pathway in diabetic complications
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| 5 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 58 drugs (DrugBank) and 100 diseases |
AGTR1 [1] AGTR1 💬AGE-RAGE signaling pathway in diabetic complications
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Losartan Losartan 💬AGE-RAGE signaling pathway in diabetic complications
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬4. AGE-RAGE signaling pathway in diabetic complications
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| 6 | Alcoholism 💬 29 genes, 80 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬Alcoholism
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Buspirone hydrochloride Buspirone hydrochloride 💬Alcoholism
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 7 | Alcoholism 💬 29 genes, 80 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬Alcoholism
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Buspirone Buspirone 💬Alcoholism
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 8 | Alcoholism 💬 29 genes, 80 drugs (DrugBank) and 63 diseases |
DRD2 [1] DRD2 💬Alcoholism
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Risperidone Risperidone 💬Alcoholism
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬8. Alcoholism
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| 9 | Alcoholism 💬 29 genes, 80 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬Alcoholism
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Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Alcoholism
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬9. Alcoholism
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| 10 | Alcoholism 💬 29 genes, 80 drugs (DrugBank) and 63 diseases |
SLC6A3 [1] SLC6A3 💬Alcoholism
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Methylphenidate Methylphenidate 💬Alcoholism
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬9. Alcoholism
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| 11 | Aldosterone synthesis and secretion 💬 20 genes, 43 drugs (DrugBank) and 63 diseases |
AGTR1 [1] AGTR1 💬Aldosterone synthesis and secretion
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Losartan potassium Losartan potassium 💬Aldosterone synthesis and secretion
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬11. Aldosterone synthesis and secretion
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| 12 | Aldosterone synthesis and secretion 💬 20 genes, 43 drugs (DrugBank) and 63 diseases |
AGTR1 [1] AGTR1 💬Aldosterone synthesis and secretion
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Losartan Losartan 💬Aldosterone synthesis and secretion
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬11. Aldosterone synthesis and secretion
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| 13 | Amphetamine addiction 💬 25 genes, 58 drugs (DrugBank) and 92 diseases |
SLC6A3 [1] SLC6A3 💬Amphetamine addiction
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Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Amphetamine addiction
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬13. Amphetamine addiction
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| 14 | Amphetamine addiction 💬 25 genes, 58 drugs (DrugBank) and 92 diseases |
SLC6A3 [1] SLC6A3 💬Amphetamine addiction
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Methylphenidate Methylphenidate 💬Amphetamine addiction
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬13. Amphetamine addiction
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| 15 | Apelin signaling pathway 💬 18 genes, 37 drugs (DrugBank) and 81 diseases |
AGTR1 [1] AGTR1 💬Apelin signaling pathway
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Losartan potassium Losartan potassium 💬Apelin signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬15. Apelin signaling pathway
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| 16 | Apelin signaling pathway 💬 18 genes, 37 drugs (DrugBank) and 81 diseases |
AGTR1 [1] AGTR1 💬Apelin signaling pathway
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Losartan Losartan 💬Apelin signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬15. Apelin signaling pathway
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| 17 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
AGTR1 [1] AGTR1 💬Calcium signaling pathway
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Losartan potassium Losartan potassium 💬Calcium signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬17. Calcium signaling pathway
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| 18 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
AGTR1 [1] AGTR1 💬Calcium signaling pathway
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Losartan Losartan 💬Calcium signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬17. Calcium signaling pathway
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| 19 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
HRH1 [1] HRH1 💬Calcium signaling pathway
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Clemastine fumarate Clemastine fumarate 💬Calcium signaling pathway
| Clemastine | 013 [2] 13, 179 💬
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| 20 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
HRH1 [1] HRH1 💬Calcium signaling pathway
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Clemastine Clemastine 💬Calcium signaling pathway
| Clemastine | 013 [2] 13, 179 💬
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| 21 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
HTR2A [1] HTR2A 💬Calcium signaling pathway
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Risperidone Risperidone 💬Calcium signaling pathway
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬21. Calcium signaling pathway
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| 22 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
DRD2 [1] DRD2 💬cAMP signaling pathway
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Risperidone Risperidone 💬cAMP signaling pathway
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬22. cAMP signaling pathway
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| 23 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
DRD2 [2] DRD2, HTR1A 💬
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Buspirone hydrochloride Buspirone hydrochloride 💬cAMP signaling pathway
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 24 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
DRD2 [2] DRD2, HTR1A 💬
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Buspirone Buspirone 💬cAMP signaling pathway
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 25 | cGMP-PKG signaling pathway 💬 48 genes, 132 drugs (DrugBank) and 123 diseases |
AGTR1 [1] AGTR1 💬cGMP-PKG signaling pathway
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Losartan potassium Losartan potassium 💬cGMP-PKG signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬25. cGMP-PKG signaling pathway
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| 26 | cGMP-PKG signaling pathway 💬 48 genes, 132 drugs (DrugBank) and 123 diseases |
AGTR1 [1] AGTR1 💬cGMP-PKG signaling pathway
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Losartan Losartan 💬cGMP-PKG signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬25. cGMP-PKG signaling pathway
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| 27 | Cocaine addiction 💬 15 genes, 67 drugs (DrugBank) and 58 diseases |
DRD2 [1] DRD2 💬Cocaine addiction
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Buspirone hydrochloride Buspirone hydrochloride 💬Cocaine addiction
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 28 | Cocaine addiction 💬 15 genes, 67 drugs (DrugBank) and 58 diseases |
DRD2 [1] DRD2 💬Cocaine addiction
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Buspirone Buspirone 💬Cocaine addiction
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 29 | Cocaine addiction 💬 15 genes, 67 drugs (DrugBank) and 58 diseases |
DRD2 [1] DRD2 💬Cocaine addiction
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Risperidone Risperidone 💬Cocaine addiction
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬29. Cocaine addiction
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| 30 | Cocaine addiction 💬 15 genes, 67 drugs (DrugBank) and 58 diseases |
SLC6A3 [1] SLC6A3 💬Cocaine addiction
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Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Cocaine addiction
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬30. Cocaine addiction
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| 31 | Cocaine addiction 💬 15 genes, 67 drugs (DrugBank) and 58 diseases |
SLC6A3 [1] SLC6A3 💬Cocaine addiction
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Methylphenidate Methylphenidate 💬Cocaine addiction
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬30. Cocaine addiction
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| 32 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
AGTR1 [1] AGTR1 💬Coronavirus disease
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Losartan potassium Losartan potassium 💬Coronavirus disease
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬32. Coronavirus disease
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| 33 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
AGTR1 [1] AGTR1 💬Coronavirus disease
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Losartan Losartan 💬Coronavirus disease
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬32. Coronavirus disease
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| 34 | Cortisol synthesis and secretion 💬 15 genes, 39 drugs (DrugBank) and 63 diseases |
AGTR1 [1] AGTR1 💬Cortisol synthesis and secretion
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Losartan potassium Losartan potassium 💬Cortisol synthesis and secretion
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬34. Cortisol synthesis and secretion
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| 35 | Cortisol synthesis and secretion 💬 15 genes, 39 drugs (DrugBank) and 63 diseases |
AGTR1 [1] AGTR1 💬Cortisol synthesis and secretion
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Losartan Losartan 💬Cortisol synthesis and secretion
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬34. Cortisol synthesis and secretion
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| 36 | Cushing syndrome 💬 23 genes, 56 drugs (DrugBank) and 71 diseases |
AGTR1 [1] AGTR1 💬Cushing syndrome
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Losartan potassium Losartan potassium 💬Cushing syndrome
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬36. Cushing syndrome
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| 37 | Cushing syndrome 💬 23 genes, 56 drugs (DrugBank) and 71 diseases |
AGTR1 [1] AGTR1 💬Cushing syndrome
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Losartan Losartan 💬Cushing syndrome
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬36. Cushing syndrome
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| 38 | Diabetic cardiomyopathy 💬 25 genes, 48 drugs (DrugBank) and 80 diseases |
AGTR1 [1] AGTR1 💬Diabetic cardiomyopathy
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Losartan potassium Losartan potassium 💬Diabetic cardiomyopathy
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬38. Diabetic cardiomyopathy
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| 39 | Diabetic cardiomyopathy 💬 25 genes, 48 drugs (DrugBank) and 80 diseases |
AGTR1 [1] AGTR1 💬Diabetic cardiomyopathy
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Losartan Losartan 💬Diabetic cardiomyopathy
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬38. Diabetic cardiomyopathy
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| 40 | Dopaminergic synapse 💬 33 genes, 105 drugs (DrugBank) and 105 diseases |
DRD2 [1] DRD2 💬Dopaminergic synapse
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Buspirone hydrochloride Buspirone hydrochloride 💬Dopaminergic synapse
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 41 | Dopaminergic synapse 💬 33 genes, 105 drugs (DrugBank) and 105 diseases |
DRD2 [1] DRD2 💬Dopaminergic synapse
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Buspirone Buspirone 💬Dopaminergic synapse
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 42 | Dopaminergic synapse 💬 33 genes, 105 drugs (DrugBank) and 105 diseases |
DRD2 [1] DRD2 💬Dopaminergic synapse
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Risperidone Risperidone 💬Dopaminergic synapse
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬42. Dopaminergic synapse
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| 43 | Dopaminergic synapse 💬 33 genes, 105 drugs (DrugBank) and 105 diseases |
SLC6A3 [1] SLC6A3 💬Dopaminergic synapse
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Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Dopaminergic synapse
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬43. Dopaminergic synapse
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| 44 | Dopaminergic synapse 💬 33 genes, 105 drugs (DrugBank) and 105 diseases |
SLC6A3 [1] SLC6A3 💬Dopaminergic synapse
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Methylphenidate Methylphenidate 💬Dopaminergic synapse
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬43. Dopaminergic synapse
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| 45 | Gap junction 💬 27 genes, 103 drugs (DrugBank) and 87 diseases |
DRD2 [1] DRD2 💬Gap junction
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Buspirone hydrochloride Buspirone hydrochloride 💬Gap junction
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 46 | Gap junction 💬 27 genes, 103 drugs (DrugBank) and 87 diseases |
DRD2 [1] DRD2 💬Gap junction
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Buspirone Buspirone 💬Gap junction
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 47 | Gap junction 💬 27 genes, 103 drugs (DrugBank) and 87 diseases |
DRD2 [2] DRD2, HTR2A 💬
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Risperidone Risperidone 💬Gap junction
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬47. Gap junction
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| 48 | GnRH secretion 💬 27 genes, 49 drugs (DrugBank) and 62 diseases |
KCNJ11 [1] KCNJ11 💬GnRH secretion
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Minoxidil Minoxidil 💬GnRH secretion
| Minoxidil | 179 [1] 179 💬48. GnRH secretion
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| 49 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
AGTR1 [1] AGTR1 💬Hormone signaling
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Losartan potassium Losartan potassium 💬Hormone signaling
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬49. Hormone signaling
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| 50 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
AGTR1 [1] AGTR1 💬Hormone signaling
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Losartan Losartan 💬Hormone signaling
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬49. Hormone signaling
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| 51 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
DRD2 [1] DRD2 💬Hormone signaling
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Buspirone hydrochloride Buspirone hydrochloride 💬Hormone signaling
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 52 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
DRD2 [1] DRD2 💬Hormone signaling
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Buspirone Buspirone 💬Hormone signaling
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 53 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
DRD2 [1] DRD2 💬Hormone signaling
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Risperidone Risperidone 💬Hormone signaling
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬53. Hormone signaling
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| 54 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
HRH1 [1] HRH1 💬Inflammatory mediator regulation of TRP channels
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Clemastine fumarate Clemastine fumarate 💬Inflammatory mediator regulation of TRP channels
| Clemastine | 013 [2] 13, 179 💬
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| 55 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
HRH1 [1] HRH1 💬Inflammatory mediator regulation of TRP channels
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Clemastine Clemastine 💬Inflammatory mediator regulation of TRP channels
| Clemastine | 013 [2] 13, 179 💬
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| 56 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
HTR2A [1] HTR2A 💬Inflammatory mediator regulation of TRP channels
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Risperidone Risperidone 💬Inflammatory mediator regulation of TRP channels
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬56. Inflammatory mediator regulation of TRP channels
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| 57 | Insulin secretion 💬 16 genes, 51 drugs (DrugBank) and 61 diseases |
ABCC8 [2] ABCC8, KCNJ11 💬
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Minoxidil Minoxidil 💬Insulin secretion
| Minoxidil | 179 [1] 179 💬57. Insulin secretion
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| 58 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
DRD2 [2] DRD2, HTR1A 💬
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Buspirone hydrochloride Buspirone hydrochloride 💬Neuroactive ligand signaling
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 59 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
DRD2 [2] DRD2, HTR1A 💬
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Buspirone Buspirone 💬Neuroactive ligand signaling
| Buspirone | 006 [3] 6 , 51, 179 💬
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| 60 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
DRD2 [2] DRD2, HTR2A 💬
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Risperidone Risperidone 💬Neuroactive ligand signaling
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬60. Neuroactive ligand signaling
|
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| 61 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
HRH1 [1] HRH1 💬Neuroactive ligand signaling
|
Clemastine fumarate Clemastine fumarate 💬Neuroactive ligand signaling
| Clemastine | 013 [2] 13, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 62 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
HRH1 [1] HRH1 💬Neuroactive ligand signaling
|
Clemastine Clemastine 💬Neuroactive ligand signaling
| Clemastine | 013 [2] 13, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 63 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Neuroactive ligand signaling
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬63. Neuroactive ligand signaling
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 64 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Methylphenidate Methylphenidate 💬Neuroactive ligand signaling
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬63. Neuroactive ligand signaling
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 65 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
AGTR1 [1] AGTR1 💬Neuroactive ligand-receptor interaction
|
Losartan potassium Losartan potassium 💬Neuroactive ligand-receptor interaction
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬65. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 66 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
AGTR1 [1] AGTR1 💬Neuroactive ligand-receptor interaction
|
Losartan Losartan 💬Neuroactive ligand-receptor interaction
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬65. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 67 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
DRD2 [2] DRD2, HTR1A 💬
|
Buspirone hydrochloride Buspirone hydrochloride 💬Neuroactive ligand-receptor interaction
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 68 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
DRD2 [2] DRD2, HTR1A 💬
|
Buspirone Buspirone 💬Neuroactive ligand-receptor interaction
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 69 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
DRD2 [2] DRD2, HTR2A 💬
|
Risperidone Risperidone 💬Neuroactive ligand-receptor interaction
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬69. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 70 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
HRH1 [1] HRH1 💬Neuroactive ligand-receptor interaction
|
Clemastine fumarate Clemastine fumarate 💬Neuroactive ligand-receptor interaction
| Clemastine | 013 [2] 13, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 71 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
HRH1 [1] HRH1 💬Neuroactive ligand-receptor interaction
|
Clemastine Clemastine 💬Neuroactive ligand-receptor interaction
| Clemastine | 013 [2] 13, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 72 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 71 diseases |
DRD2 [1] DRD2 💬Parkinson disease
|
Buspirone hydrochloride Buspirone hydrochloride 💬Parkinson disease
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 73 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 71 diseases |
DRD2 [1] DRD2 💬Parkinson disease
|
Buspirone Buspirone 💬Parkinson disease
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 74 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 71 diseases |
DRD2 [1] DRD2 💬Parkinson disease
|
Risperidone Risperidone 💬Parkinson disease
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬74. Parkinson disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 75 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 71 diseases |
SLC6A3 [1] SLC6A3 💬Parkinson disease
|
Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Parkinson disease
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬75. Parkinson disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 76 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 71 diseases |
SLC6A3 [1] SLC6A3 💬Parkinson disease
|
Methylphenidate Methylphenidate 💬Parkinson disease
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬75. Parkinson disease
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 77 | Pathways in cancer 💬 116 genes, 235 drugs (DrugBank) and 150 diseases |
AGTR1 [1] AGTR1 💬Pathways in cancer
|
Losartan potassium Losartan potassium 💬Pathways in cancer
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬77. Pathways in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 78 | Pathways in cancer 💬 116 genes, 235 drugs (DrugBank) and 150 diseases |
AGTR1 [1] AGTR1 💬Pathways in cancer
|
Losartan Losartan 💬Pathways in cancer
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬77. Pathways in cancer
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 79 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
SLC6A3 [1] SLC6A3 💬Pathways of neurodegeneration - multiple diseases
|
Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Pathways of neurodegeneration - multiple diseases
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬79. Pathways of neurodegeneration - multiple diseases
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 80 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
SLC6A3 [1] SLC6A3 💬Pathways of neurodegeneration - multiple diseases
|
Methylphenidate Methylphenidate 💬Pathways of neurodegeneration - multiple diseases
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬79. Pathways of neurodegeneration - multiple diseases
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 81 | Phospholipase D signaling pathway 💬 24 genes, 60 drugs (DrugBank) and 84 diseases |
AGTR1 [1] AGTR1 💬Phospholipase D signaling pathway
|
Losartan potassium Losartan potassium 💬Phospholipase D signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬81. Phospholipase D signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 82 | Phospholipase D signaling pathway 💬 24 genes, 60 drugs (DrugBank) and 84 diseases |
AGTR1 [1] AGTR1 💬Phospholipase D signaling pathway
|
Losartan Losartan 💬Phospholipase D signaling pathway
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬81. Phospholipase D signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 83 | Rap1 signaling pathway 💬 47 genes, 115 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬Rap1 signaling pathway
|
Buspirone hydrochloride Buspirone hydrochloride 💬Rap1 signaling pathway
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 84 | Rap1 signaling pathway 💬 47 genes, 115 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬Rap1 signaling pathway
|
Buspirone Buspirone 💬Rap1 signaling pathway
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 85 | Rap1 signaling pathway 💬 47 genes, 115 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬Rap1 signaling pathway
|
Risperidone Risperidone 💬Rap1 signaling pathway
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬85. Rap1 signaling pathway
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 86 | Renin secretion 💬 28 genes, 90 drugs (DrugBank) and 108 diseases |
AGTR1 [1] AGTR1 💬Renin secretion
|
Losartan potassium Losartan potassium 💬Renin secretion
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬86. Renin secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 87 | Renin secretion 💬 28 genes, 90 drugs (DrugBank) and 108 diseases |
AGTR1 [1] AGTR1 💬Renin secretion
|
Losartan Losartan 💬Renin secretion
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬86. Renin secretion
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 88 | Renin-angiotensin system 💬 6 genes, 22 drugs (DrugBank) and 33 diseases |
AGTR1 [1] AGTR1 💬Renin-angiotensin system
|
Losartan potassium Losartan potassium 💬Renin-angiotensin system
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬88. Renin-angiotensin system
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 89 | Renin-angiotensin system 💬 6 genes, 22 drugs (DrugBank) and 33 diseases |
AGTR1 [1] AGTR1 💬Renin-angiotensin system
|
Losartan Losartan 💬Renin-angiotensin system
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬88. Renin-angiotensin system
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 90 | Serotonergic synapse 💬 40 genes, 130 drugs (DrugBank) and 89 diseases |
HTR1A [1] HTR1A 💬Serotonergic synapse
|
Buspirone hydrochloride Buspirone hydrochloride 💬Serotonergic synapse
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 91 | Serotonergic synapse 💬 40 genes, 130 drugs (DrugBank) and 89 diseases |
HTR1A [1] HTR1A 💬Serotonergic synapse
|
Buspirone Buspirone 💬Serotonergic synapse
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 92 | Serotonergic synapse 💬 40 genes, 130 drugs (DrugBank) and 89 diseases |
HTR2A [1] HTR2A 💬Serotonergic synapse
|
Risperidone Risperidone 💬Serotonergic synapse
| Risperidone | 008 [6] 8 , 74, 156, 179, 187, 206 💬92. Serotonergic synapse
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 93 | Synaptic vesicle cycle 💬 8 genes, 32 drugs (DrugBank) and 43 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Methylphenidate hydrochloride Methylphenidate hydrochloride 💬Synaptic vesicle cycle
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬93. Synaptic vesicle cycle
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 94 | Synaptic vesicle cycle 💬 8 genes, 32 drugs (DrugBank) and 43 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Methylphenidate Methylphenidate 💬Synaptic vesicle cycle
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬93. Synaptic vesicle cycle
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 95 | Taste transduction 💬 29 genes, 93 drugs (DrugBank) and 78 diseases |
HTR1A [1] HTR1A 💬Taste transduction
|
Buspirone hydrochloride Buspirone hydrochloride 💬Taste transduction
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 96 | Taste transduction 💬 29 genes, 93 drugs (DrugBank) and 78 diseases |
HTR1A [1] HTR1A 💬Taste transduction
|
Buspirone Buspirone 💬Taste transduction
| Buspirone | 006 [3] 6 , 51, 179 💬
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 97 | Type II diabetes mellitus 💬 15 genes, 44 drugs (DrugBank) and 100 diseases |
ABCC8 [2] ABCC8, KCNJ11 💬
|
Minoxidil Minoxidil 💬Type II diabetes mellitus
| Minoxidil | 179 [1] 179 💬97. Type II diabetes mellitus
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 98 | Vascular smooth muscle contraction 💬 32 genes, 95 drugs (DrugBank) and 74 diseases |
AGTR1 [1] AGTR1 💬Vascular smooth muscle contraction
|
Losartan potassium Losartan potassium 💬Vascular smooth muscle contraction
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬98. Vascular smooth muscle contraction
|
||||||||||||||||||||||||||||||||||||||||||||||||||
| 99 | Vascular smooth muscle contraction 💬 32 genes, 95 drugs (DrugBank) and 74 diseases |
AGTR1 [1] AGTR1 💬Vascular smooth muscle contraction
|
Losartan Losartan 💬Vascular smooth muscle contraction
| Losartan | 017 [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬98. Vascular smooth muscle contraction
|
ABC transporters
4 genes, 14 drugs (DrugBank) and 10 diseases
Adrenergic signaling in cardiomyocytes
31 genes, 86 drugs (DrugBank) and 81 diseases
AGE-RAGE signaling pathway in diabetic complications
28 genes, 58 drugs (DrugBank) and 100 diseases
Alcoholism
29 genes, 80 drugs (DrugBank) and 63 diseases
Aldosterone synthesis and secretion
20 genes, 43 drugs (DrugBank) and 63 diseases
Amphetamine addiction
25 genes, 58 drugs (DrugBank) and 92 diseases
Apelin signaling pathway
18 genes, 37 drugs (DrugBank) and 81 diseases
Calcium signaling pathway
82 genes, 215 drugs (DrugBank) and 140 diseases
cAMP signaling pathway
67 genes, 191 drugs (DrugBank) and 133 diseases
cGMP-PKG signaling pathway
48 genes, 132 drugs (DrugBank) and 123 diseases
Cocaine addiction
15 genes, 67 drugs (DrugBank) and 58 diseases
Coronavirus disease
56 genes, 115 drugs (DrugBank) and 109 diseases
Cortisol synthesis and secretion
15 genes, 39 drugs (DrugBank) and 63 diseases
Cushing syndrome
23 genes, 56 drugs (DrugBank) and 71 diseases
Diabetic cardiomyopathy
25 genes, 48 drugs (DrugBank) and 80 diseases
Dopaminergic synapse
33 genes, 105 drugs (DrugBank) and 105 diseases
Gap junction
27 genes, 103 drugs (DrugBank) and 87 diseases
GnRH secretion
27 genes, 49 drugs (DrugBank) and 62 diseases
Hormone signaling
64 genes, 217 drugs (DrugBank) and 150 diseases
Inflammatory mediator regulation of TRP channels
26 genes, 55 drugs (DrugBank) and 70 diseases
Insulin secretion
16 genes, 51 drugs (DrugBank) and 61 diseases
Neuroactive ligand signaling
92 genes, 239 drugs (DrugBank) and 118 diseases
Neuroactive ligand-receptor interaction
156 genes, 371 drugs (DrugBank) and 171 diseases
Parkinson disease
24 genes, 73 drugs (DrugBank) and 71 diseases
Pathways in cancer
116 genes, 235 drugs (DrugBank) and 150 diseases
Pathways of neurodegeneration - multiple diseases
64 genes, 143 drugs (DrugBank) and 141 diseases
Phospholipase D signaling pathway
24 genes, 60 drugs (DrugBank) and 84 diseases
Rap1 signaling pathway
47 genes, 115 drugs (DrugBank) and 101 diseases
Renin secretion
28 genes, 90 drugs (DrugBank) and 108 diseases
Renin-angiotensin system
6 genes, 22 drugs (DrugBank) and 33 diseases
Serotonergic synapse
40 genes, 130 drugs (DrugBank) and 89 diseases
Synaptic vesicle cycle
8 genes, 32 drugs (DrugBank) and 43 diseases
Taste transduction
29 genes, 93 drugs (DrugBank) and 78 diseases
Type II diabetes mellitus
15 genes, 44 drugs (DrugBank) and 100 diseases
Vascular smooth muscle contraction
32 genes, 95 drugs (DrugBank) and 74 diseases
