Target Gene/Pathway Pathway / Gene

---

Search results

---

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
2	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
3	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine bitartrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 1. Adrenergic signaling in cardiomyocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
4	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Adrenergic signaling in cardiomyocytes × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
5	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Adrenergic signaling in cardiomyocytes × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 4. Adrenergic signaling in cardiomyocytes × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
6	Adrenergic signaling in cardiomyocytes 💬	[2] CACNA2D1, CACNA2D2 💬 Adrenergic signaling in cardiomyocytes × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor	Mirogabalin 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Mirogabalin Mirogabalin	Mirogabalin	[1] 70 💬 6. Adrenergic signaling in cardiomyocytes × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
7	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Adrenergic signaling in cardiomyocytes × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Gabapentin 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 7. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
8	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Adrenergic signaling in cardiomyocytes × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Pregabalin 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Pregabalin Lyrica LYRICA CR PREGABALIN CAPSULES, CV PREGABALIN EXTENDED RELEASE PREGABLIN	Pregabalin	[5] 13, 36, 46, 70, 298 💬 8. Adrenergic signaling in cardiomyocytes × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
9	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Bupivacaine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Bupivacaine hydrochloride Bupivacaine hydrochloride hydrate Marcaine BUPIVACAINE HCL MARCAINE SPINAL SENSORCAINE BUPIVACAINE BUPIVACAINE HCI BUPIVACAINE HYDROCHLORIDE INJECTION, SOLUTION BUPIVACAINE HYDROCHLORIDE WITH DEXTROSE BUPIVICAINE HYDROCHLORIDE SENSORCAINE MPF	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 9. Adrenergic signaling in cardiomyocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
10	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Bupivacaine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Bupivacaine Bucaine Exparel	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 9. Adrenergic signaling in cardiomyocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
11	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 11. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
12	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 11. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
13	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride monohydrate 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 11. Adrenergic signaling in cardiomyocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
14	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine hydrochloride 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 14. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
15	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬 Adrenergic signaling in cardiomyocytes × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine 💬 Adrenergic signaling in cardiomyocytes × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 14. Adrenergic signaling in cardiomyocytes × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
16	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alcoholism × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Alcoholism × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 16. Alcoholism × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
17	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alcoholism × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Alcoholism × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 16. Alcoholism × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
18	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alcoholism × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Alcoholism × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 18. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
19	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alcoholism × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Alcoholism × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 18. Alcoholism × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
20	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Aldosterone synthesis and secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Aldosterone synthesis and secretion × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 20. Aldosterone synthesis and secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
21	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Aldosterone synthesis and secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Aldosterone synthesis and secretion × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 20. Aldosterone synthesis and secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
22	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Alzheimer disease × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Alzheimer disease × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 22. Alzheimer disease × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
23	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Alzheimer disease × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Alzheimer disease × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 22. Alzheimer disease × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
24	Alzheimer disease 💬	[4] CHRM1, CHRM3, CHRM5, CHRNA7 💬 Alzheimer disease × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5 CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor	Rocuronium bromide 💬 Alzheimer disease × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 24. Alzheimer disease × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
25	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alzheimer disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Alzheimer disease × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 25. Alzheimer disease × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
26	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alzheimer disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Alzheimer disease × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 25. Alzheimer disease × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
27	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alzheimer disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Alzheimer disease × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 27. Alzheimer disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
28	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Alzheimer disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Alzheimer disease × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 27. Alzheimer disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
29	Alzheimer disease 💬	[1] PTGS2 💬 Alzheimer disease × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Alzheimer disease × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 29. Alzheimer disease × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
30	Alzheimer disease 💬	[1] PTGS2 💬 Alzheimer disease × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Alzheimer disease × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 30. Alzheimer disease × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
31	Alzheimer disease 💬	[1] PTGS2 💬 Alzheimer disease × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Alzheimer disease × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 31. Alzheimer disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
32	Alzheimer disease 💬	[1] PTGS2 💬 Alzheimer disease × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Alzheimer disease × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 32. Alzheimer disease × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
33	Alzheimer disease 💬	[1] PTGS2 💬 Alzheimer disease × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Alzheimer disease × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 32. Alzheimer disease × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
34	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬 Amphetamine addiction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Amphetamine addiction × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 34. Amphetamine addiction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
35	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬 Amphetamine addiction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Amphetamine addiction × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 34. Amphetamine addiction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
36	Amphetamine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amphetamine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Amphetamine addiction × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 36. Amphetamine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
37	Amphetamine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amphetamine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Amphetamine addiction × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 36. Amphetamine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
38	Amphetamine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amphetamine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Amphetamine addiction × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 38. Amphetamine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
39	Amphetamine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amphetamine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Amphetamine addiction × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 38. Amphetamine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
40	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Epinephrine 💬 AMPK signaling pathway × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 40. AMPK signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
41	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Epinephrine hydrochloride 💬 AMPK signaling pathway × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 40. AMPK signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
42	AMPK signaling pathway 💬	[1] ADRA1A 💬 AMPK signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1	Epinephrine bitartrate 💬 AMPK signaling pathway × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 40. AMPK signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
43	Amyotrophic lateral sclerosis 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amyotrophic lateral sclerosis × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Amyotrophic lateral sclerosis × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 43. Amyotrophic lateral sclerosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
44	Amyotrophic lateral sclerosis 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amyotrophic lateral sclerosis × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Amyotrophic lateral sclerosis × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 43. Amyotrophic lateral sclerosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
45	Amyotrophic lateral sclerosis 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amyotrophic lateral sclerosis × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Amyotrophic lateral sclerosis × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 45. Amyotrophic lateral sclerosis × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
46	Amyotrophic lateral sclerosis 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amyotrophic lateral sclerosis × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Amyotrophic lateral sclerosis × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 45. Amyotrophic lateral sclerosis × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
47	Apelin signaling pathway 💬	[1] PDE3B 💬 Apelin signaling pathway × Name Full Name PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Apelin signaling pathway × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 47. Apelin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
48	Apelin signaling pathway 💬	[1] PLAT 💬 Apelin signaling pathway × Name Full Name PLAT tissue-type plasminogen activator isoform 1 preproprotein	Aminocaproic acid 💬 Apelin signaling pathway × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 48. Apelin signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
49	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬 Arachidonic acid metabolism × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Arachidonic acid metabolism × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 49. Arachidonic acid metabolism × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
50	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬 Arachidonic acid metabolism × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Arachidonic acid metabolism × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 50. Arachidonic acid metabolism × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
51	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬 Arachidonic acid metabolism × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Arachidonic acid metabolism × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 50. Arachidonic acid metabolism × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
52	Arachidonic acid metabolism 💬	[1] PTGS2 💬 Arachidonic acid metabolism × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Arachidonic acid metabolism × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 52. Arachidonic acid metabolism × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
53	Arachidonic acid metabolism 💬	[1] PTGS2 💬 Arachidonic acid metabolism × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Arachidonic acid metabolism × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 53. Arachidonic acid metabolism × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
54	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 54. Arrhythmogenic right ventricular cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
55	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 54. Arrhythmogenic right ventricular cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
56	Arrhythmogenic right ventricular cardiomyopathy 💬	[2] CACNA2D1, CACNA2D2 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor	Mirogabalin 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Other Names Mirogabalin Mirogabalin	Mirogabalin	[1] 70 💬 56. Arrhythmogenic right ventricular cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
57	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Gabapentin 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 57. Arrhythmogenic right ventricular cardiomyopathy × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
58	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Pregabalin 💬 Arrhythmogenic right ventricular cardiomyopathy × Name Other Names Pregabalin Lyrica LYRICA CR PREGABALIN CAPSULES, CV PREGABALIN EXTENDED RELEASE PREGABLIN	Pregabalin	[5] 13, 36, 46, 70, 298 💬 58. Arrhythmogenic right ventricular cardiomyopathy × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
59	Breast cancer 💬	[1] TNFSF11 💬 Breast cancer × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 Breast cancer × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 59. Breast cancer × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
60	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬 C-type lectin receptor signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 C-type lectin receptor signaling pathway × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 60. C-type lectin receptor signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
61	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬 C-type lectin receptor signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 C-type lectin receptor signaling pathway × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 61. C-type lectin receptor signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
62	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬 C-type lectin receptor signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 C-type lectin receptor signaling pathway × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 62. C-type lectin receptor signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
63	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬 C-type lectin receptor signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 C-type lectin receptor signaling pathway × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 63. C-type lectin receptor signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
64	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬 C-type lectin receptor signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 C-type lectin receptor signaling pathway × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 63. C-type lectin receptor signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
65	Cadherin signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Cadherin signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam 💬 Cadherin signaling × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 65. Cadherin signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
66	Cadherin signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Cadherin signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam hydrochloride 💬 Cadherin signaling × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 65. Cadherin signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
67	Cadherin signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Cadherin signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam maleate 💬 Cadherin signaling × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 65. Cadherin signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
68	Cadherin signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Cadherin signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Cadherin signaling × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 68. Cadherin signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
69	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Bupivacaine hydrochloride 💬 Cadherin signaling × Name Other Names Bupivacaine hydrochloride Bupivacaine hydrochloride hydrate Marcaine BUPIVACAINE HCL MARCAINE SPINAL SENSORCAINE BUPIVACAINE BUPIVACAINE HCI BUPIVACAINE HYDROCHLORIDE INJECTION, SOLUTION BUPIVACAINE HYDROCHLORIDE WITH DEXTROSE BUPIVICAINE HYDROCHLORIDE SENSORCAINE MPF	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 69. Cadherin signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
70	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Bupivacaine 💬 Cadherin signaling × Name Other Names Bupivacaine Bucaine Exparel	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 69. Cadherin signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
71	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine 💬 Cadherin signaling × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 71. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
72	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride 💬 Cadherin signaling × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 71. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
73	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Lidocaine hydrochloride monohydrate 💬 Cadherin signaling × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 71. Cadherin signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
74	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine hydrochloride 💬 Cadherin signaling × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 74. Cadherin signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
75	Cadherin signaling 💬	[1] SCN5A 💬 Cadherin signaling × Name Full Name SCN5A sodium channel protein type 5 subunit alpha isoform a	Ropivacaine 💬 Cadherin signaling × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 74. Cadherin signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
76	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Calcium signaling pathway × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 76. Calcium signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
77	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Calcium signaling pathway × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 76. Calcium signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
78	Calcium signaling pathway 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Calcium signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Calcium signaling pathway × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 76. Calcium signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
79	Calcium signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Calcium signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Calcium signaling pathway × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 79. Calcium signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
80	Calcium signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Calcium signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Calcium signaling pathway × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 79. Calcium signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
81	Calcium signaling pathway 💬	[5] CHRM1, CHRM2, CHRM3, CHRM5, CHRNA7 💬 Calcium signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5 CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor	Rocuronium bromide 💬 Calcium signaling pathway × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 81. Calcium signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
82	Calcium signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Calcium signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Calcium signaling pathway × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 82. Calcium signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
83	Calcium signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Calcium signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Calcium signaling pathway × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 82. Calcium signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
84	Calcium signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Calcium signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Calcium signaling pathway × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 84. Calcium signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
85	Calcium signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Calcium signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Calcium signaling pathway × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 84. Calcium signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
86	Calcium signaling pathway 💬	[1] HRH1 💬 Calcium signaling pathway × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine 💬 Calcium signaling pathway × Name Other Names Diphenhydramine Restamin	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 86. Calcium signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
87	Calcium signaling pathway 💬	[1] HRH1 💬 Calcium signaling pathway × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine hydrochloride 💬 Calcium signaling pathway × Name Other Names Diphenhydramine hydrochloride Benadryl	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 86. Calcium signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
88	Calcium signaling pathway 💬	[1] HRH1 💬 Calcium signaling pathway × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine salicylate 💬 Calcium signaling pathway × Name Other Names Diphenhydramine salicylate Diphenhydramine salicylate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 86. Calcium signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
89	Calcium signaling pathway 💬	[1] HRH1 💬 Calcium signaling pathway × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine citrate 💬 Calcium signaling pathway × Name Other Names Diphenhydramine citrate Diphenhydramine citrate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 86. Calcium signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
90	Calcium signaling pathway 💬	[1] OXTR 💬 Calcium signaling pathway × Name Full Name OXTR oxytocin receptor	Oxytocin 💬 Calcium signaling pathway × Name Other Names Oxytocin Pitocin Syntocinon	Oxytocin	[8]  6 , 70, 72, 127, 168, 193, 206, 226 💬 90. Calcium signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 127 Frontotemporal lobar degeneration;Frontotemporal dementia, behavioral abnormal type;Frontotemporal dementia;Semantic dementia; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 193 Prader-Willi syndrome; 206 Fragile X syndrome; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
91	Calcium signaling pathway 💬	[1] PTGER1 💬 Calcium signaling pathway × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Alprostadil 💬 Calcium signaling pathway × Name Other Names Alprostadil Prostin VR pediatric Caverject Edex Muse CAVERJECT IMPULSE PROSTIN	Alprostadil	[2] 51, 70 💬 91. Calcium signaling pathway × Disease ID Name 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis;
92	Calcium signaling pathway 💬	[1] PTGER1 💬 Calcium signaling pathway × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost 💬 Calcium signaling pathway × Name Other Names Limaprost Limaprost	Limaprost	[1] 70 💬 92. Calcium signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
93	Calcium signaling pathway 💬	[1] PTGER1 💬 Calcium signaling pathway × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost alfadex 💬 Calcium signaling pathway × Name Other Names Limaprost alfadex Opalmon	Limaprost	[1] 70 💬 92. Calcium signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
94	Calcium signaling pathway 💬	[1] PTGER3 💬 Calcium signaling pathway × Name Full Name PTGER3 prostaglandin E2 receptor EP3 subtype isoform 4	Misoprostol 💬 Calcium signaling pathway × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 94. Calcium signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
95	Calcium signaling pathway 💬	[1] TBXA2R 💬 Calcium signaling pathway × Name Full Name TBXA2R thromboxane A2 receptor isoform alpha	Cilostazol 💬 Calcium signaling pathway × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 95. Calcium signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
96	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine 💬 cAMP signaling pathway × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 96. cAMP signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
97	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine hydrochloride 💬 cAMP signaling pathway × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 96. cAMP signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
98	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬 cAMP signaling pathway × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine bitartrate 💬 cAMP signaling pathway × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 96. cAMP signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
99	cAMP signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 cAMP signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 cAMP signaling pathway × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 99. cAMP signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
100	cAMP signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 cAMP signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 cAMP signaling pathway × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 99. cAMP signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
101	cAMP signaling pathway 💬	[2] CHRM1, CHRM2 💬 cAMP signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2	Rocuronium bromide 💬 cAMP signaling pathway × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 101. cAMP signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
102	cAMP signaling pathway 💬	[2] GABBR1, GABBR2 💬 cAMP signaling pathway × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 cAMP signaling pathway × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 102. cAMP signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
103	cAMP signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 cAMP signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 cAMP signaling pathway × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 103. cAMP signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
104	cAMP signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 cAMP signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 cAMP signaling pathway × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 103. cAMP signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
105	cAMP signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 cAMP signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 cAMP signaling pathway × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 105. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
106	cAMP signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 cAMP signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 cAMP signaling pathway × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 105. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
107	cAMP signaling pathway 💬	[1] OXTR 💬 cAMP signaling pathway × Name Full Name OXTR oxytocin receptor	Oxytocin 💬 cAMP signaling pathway × Name Other Names Oxytocin Pitocin Syntocinon	Oxytocin	[8]  6 , 70, 72, 127, 168, 193, 206, 226 💬 107. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 127 Frontotemporal lobar degeneration;Frontotemporal dementia, behavioral abnormal type;Frontotemporal dementia;Semantic dementia; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 193 Prader-Willi syndrome; 206 Fragile X syndrome; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
108	cAMP signaling pathway 💬	[2] PDE3A, PDE3B 💬 cAMP signaling pathway × Name Full Name PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform 1 PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 cAMP signaling pathway × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 108. cAMP signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
109	cAMP signaling pathway 💬	[2] PTGER2, PTGER3 💬 cAMP signaling pathway × Name Full Name PTGER2 prostaglandin E2 receptor EP2 subtype PTGER3 prostaglandin E2 receptor EP3 subtype isoform 4	Misoprostol 💬 cAMP signaling pathway × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 109. cAMP signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
110	Carbohydrate digestion and absorption 💬	[1] CACNA1D 💬 Carbohydrate digestion and absorption × Name Full Name CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Carbohydrate digestion and absorption × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 110. Carbohydrate digestion and absorption × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
111	Carbohydrate digestion and absorption 💬	[1] CACNA1D 💬 Carbohydrate digestion and absorption × Name Full Name CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Carbohydrate digestion and absorption × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 110. Carbohydrate digestion and absorption × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
112	Cardiac muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cardiac muscle contraction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Cardiac muscle contraction × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 112. Cardiac muscle contraction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
113	Cardiac muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cardiac muscle contraction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Cardiac muscle contraction × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 112. Cardiac muscle contraction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
114	Cardiac muscle contraction 💬	[2] CACNA2D1, CACNA2D2 💬 Cardiac muscle contraction × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor	Mirogabalin 💬 Cardiac muscle contraction × Name Other Names Mirogabalin Mirogabalin	Mirogabalin	[1] 70 💬 114. Cardiac muscle contraction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
115	Cardiac muscle contraction 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Cardiac muscle contraction × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Gabapentin 💬 Cardiac muscle contraction × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 115. Cardiac muscle contraction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
116	Cardiac muscle contraction 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Cardiac muscle contraction × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Pregabalin 💬 Cardiac muscle contraction × Name Other Names Pregabalin Lyrica LYRICA CR PREGABALIN CAPSULES, CV PREGABALIN EXTENDED RELEASE PREGABLIN	Pregabalin	[5] 13, 36, 46, 70, 298 💬 116. Cardiac muscle contraction × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
117	Cellular senescence 💬	[1] CACNA1D 💬 Cellular senescence × Name Full Name CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Cellular senescence × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 117. Cellular senescence × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
118	Cellular senescence 💬	[1] CACNA1D 💬 Cellular senescence × Name Full Name CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Cellular senescence × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 117. Cellular senescence × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
119	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 cGMP-PKG signaling pathway × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 119. cGMP-PKG signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
120	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 119. cGMP-PKG signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
121	cGMP-PKG signaling pathway 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 cGMP-PKG signaling pathway × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 cGMP-PKG signaling pathway × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 119. cGMP-PKG signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
122	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine 💬 cGMP-PKG signaling pathway × Name Other Names Clonidine Catarpres-TTS CLONIDINE TRANSDERMAL SYSTEM	Clonidine	[3]  6 , 65, 70 💬 122. cGMP-PKG signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
123	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Clonidine hydrochloride Nexiclon Kapvay Duraclon Catapres JAVADIN NEXICLON XR ONYDA XR QLONILIK CLONIDINE CLONIDINE HCI	Clonidine	[3]  6 , 65, 70 💬 122. cGMP-PKG signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
124	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 cGMP-PKG signaling pathway × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 124. cGMP-PKG signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
125	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 cGMP-PKG signaling pathway × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 124. cGMP-PKG signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
126	cGMP-PKG signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 cGMP-PKG signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 126. cGMP-PKG signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
127	cGMP-PKG signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 cGMP-PKG signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 cGMP-PKG signaling pathway × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 126. cGMP-PKG signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
128	cGMP-PKG signaling pathway 💬	[1] OPRD1 💬 cGMP-PKG signaling pathway × Name Full Name OPRD1 delta-type opioid receptor	Oxycodone hydrochloride 💬 cGMP-PKG signaling pathway × Name Other Names Oxycodone hydrochloride Oxecta Oxycontin Roxicodone OXAYDO ROXYBOND OXYCODONE HCL OXYCODONE HYDCHLORIDE OXYCODONE HYDROCHLORIDE ORAL SOLUTION	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 128. cGMP-PKG signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
129	cGMP-PKG signaling pathway 💬	[1] OPRD1 💬 cGMP-PKG signaling pathway × Name Full Name OPRD1 delta-type opioid receptor	Oxycodone terephthalate 💬 cGMP-PKG signaling pathway × Name Other Names Oxycodone terephthalate Oxycodone terephthalate	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 128. cGMP-PKG signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
130	cGMP-PKG signaling pathway 💬	[1] OPRD1 💬 cGMP-PKG signaling pathway × Name Full Name OPRD1 delta-type opioid receptor	Oxycodone 💬 cGMP-PKG signaling pathway × Name Other Names Oxycodone XTAMPZA	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 128. cGMP-PKG signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
131	cGMP-PKG signaling pathway 💬	[2] PDE3A, PDE3B 💬 cGMP-PKG signaling pathway × Name Full Name PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform 1 PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 cGMP-PKG signaling pathway × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 131. cGMP-PKG signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
132	Chemical carcinogenesis - DNA adducts 💬	[1] PTGS2 💬 Chemical carcinogenesis - DNA adducts × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Chemical carcinogenesis - DNA adducts × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 132. Chemical carcinogenesis - DNA adducts × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
133	Chemical carcinogenesis - DNA adducts 💬	[1] PTGS2 💬 Chemical carcinogenesis - DNA adducts × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Chemical carcinogenesis - DNA adducts × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 133. Chemical carcinogenesis - DNA adducts × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
134	Chemical carcinogenesis - DNA adducts 💬	[1] PTGS2 💬 Chemical carcinogenesis - DNA adducts × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Chemical carcinogenesis - DNA adducts × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 134. Chemical carcinogenesis - DNA adducts × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
135	Chemical carcinogenesis - DNA adducts 💬	[1] PTGS2 💬 Chemical carcinogenesis - DNA adducts × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Chemical carcinogenesis - DNA adducts × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 135. Chemical carcinogenesis - DNA adducts × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
136	Chemical carcinogenesis - DNA adducts 💬	[1] PTGS2 💬 Chemical carcinogenesis - DNA adducts × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Chemical carcinogenesis - DNA adducts × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 135. Chemical carcinogenesis - DNA adducts × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
137	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Chemical carcinogenesis - receptor activation × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 137. Chemical carcinogenesis - receptor activation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
138	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Chemical carcinogenesis - receptor activation × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 137. Chemical carcinogenesis - receptor activation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
139	Chemical carcinogenesis - receptor activation 💬	[3] ADRB1, ADRB2, ADRB3 💬 Chemical carcinogenesis - receptor activation × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Chemical carcinogenesis - receptor activation × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 137. Chemical carcinogenesis - receptor activation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
140	Chemical carcinogenesis - receptor activation 💬	[2] ARRB1, ARRB2 💬 Chemical carcinogenesis - receptor activation × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Chemical carcinogenesis - receptor activation × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 140. Chemical carcinogenesis - receptor activation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
141	Chemical carcinogenesis - receptor activation 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Chemical carcinogenesis - receptor activation × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Chemical carcinogenesis - receptor activation × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 141. Chemical carcinogenesis - receptor activation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
142	Chemical carcinogenesis - receptor activation 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Chemical carcinogenesis - receptor activation × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Chemical carcinogenesis - receptor activation × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 141. Chemical carcinogenesis - receptor activation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
143	Chemical carcinogenesis - receptor activation 💬	[6] CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 Chemical carcinogenesis - receptor activation × Name Full Name CHRNA3 neuronal acetylcholine receptor subunit alpha-3 isoform 1 precursor CHRNA4 neuronal acetylcholine receptor subunit alpha-4 isoform 1 precursor CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor CHRNA9 neuronal acetylcholine receptor subunit alpha-9 precursor CHRNB2 neuronal acetylcholine receptor subunit beta-2 precursor CHRNB4 neuronal acetylcholine receptor subunit beta-4 isoform 1 precursor	Rocuronium bromide 💬 Chemical carcinogenesis - receptor activation × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 143. Chemical carcinogenesis - receptor activation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
144	Chemical carcinogenesis - receptor activation 💬	[1] TNFSF11 💬 Chemical carcinogenesis - receptor activation × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 Chemical carcinogenesis - receptor activation × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 144. Chemical carcinogenesis - receptor activation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
145	Chemokine signaling pathway 💬	[2] ARRB1, ARRB2 💬 Chemokine signaling pathway × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Chemokine signaling pathway × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 145. Chemokine signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
146	Cholinergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cholinergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Cholinergic synapse × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 146. Cholinergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
147	Cholinergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cholinergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Cholinergic synapse × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 146. Cholinergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
148	Cholinergic synapse 💬	[11] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 Cholinergic synapse × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5 CHRNA3 neuronal acetylcholine receptor subunit alpha-3 isoform 1 precursor CHRNA4 neuronal acetylcholine receptor subunit alpha-4 isoform 1 precursor CHRNA6 neuronal acetylcholine receptor subunit alpha-6 isoform 1 precursor CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor CHRNB2 neuronal acetylcholine receptor subunit beta-2 precursor CHRNB4 neuronal acetylcholine receptor subunit beta-4 isoform 1 precursor	Rocuronium bromide 💬 Cholinergic synapse × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 148. Cholinergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
149	Circadian entrainment 💬	[2] CACNA1C, CACNA1D 💬 Circadian entrainment × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Circadian entrainment × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 149. Circadian entrainment × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
150	Circadian entrainment 💬	[2] CACNA1C, CACNA1D 💬 Circadian entrainment × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Circadian entrainment × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 149. Circadian entrainment × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
151	Circadian entrainment 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Circadian entrainment × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Circadian entrainment × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 151. Circadian entrainment × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
152	Circadian entrainment 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Circadian entrainment × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Circadian entrainment × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 151. Circadian entrainment × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
153	Circadian entrainment 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Circadian entrainment × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Circadian entrainment × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 153. Circadian entrainment × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
154	Circadian entrainment 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Circadian entrainment × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Circadian entrainment × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 153. Circadian entrainment × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
155	Cocaine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Cocaine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Cocaine addiction × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 155. Cocaine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
156	Cocaine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Cocaine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Cocaine addiction × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 155. Cocaine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
157	Cocaine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Cocaine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Cocaine addiction × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 157. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
158	Cocaine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Cocaine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Cocaine addiction × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 157. Cocaine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
159	Complement and coagulation cascades 💬	[2] PLAT, PLG 💬 Complement and coagulation cascades × Name Full Name PLAT tissue-type plasminogen activator isoform 1 preproprotein PLG plasminogen isoform 1 precursor	Aminocaproic acid 💬 Complement and coagulation cascades × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 159. Complement and coagulation cascades × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
160	Complement and coagulation cascades 💬	[1] PLG 💬 Complement and coagulation cascades × Name Full Name PLG plasminogen isoform 1 precursor	Tranexamic acid 💬 Complement and coagulation cascades × Name Other Names Tranexamic acid Cyklokapron Rikavarin Transamin TRANEXAMIC ACID IN SODIUM CHLORIDE	Tranexamic acid	[7] 46, 65, 70, 215, 227, 274, 299 💬 160. Complement and coagulation cascades × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 215 Tetralogy of Fallot;Fallot tetralogy; 227 Osler disease;Hereditary hemorrhagic telangiectasia;HHT;Osler-Weber-Rendu disease; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
161	Complement and coagulation cascades 💬	[1] SERPINC1 💬 Complement and coagulation cascades × Name Full Name SERPINC1 antithrombin-III isoform 1 precursor	Heparin sodium 💬 Complement and coagulation cascades × Name Other Names Heparin sodium Parnaparin sodium Liquemin sodium HEPARIN SODIUM AND DEXTROSE HEPARIN SODIUM IN DEXTROSE HEPARIN SODIUM IN SODIUM CHLORIDE	Heparin	[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬 161. Complement and coagulation cascades × Disease ID Name 47 Buerger disease;Thromboangiitis obliterans; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 60 Aplastic anemia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 224 Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation; 299 Cystic fibrosis;CF; 316 Carnitine cycle disorder;Disorders of carnitine transport and the carnitine cycle;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;LC-FAOD;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Primary Carnitine deficiency;OCTN2 deficiency; 317 Trifunctional protein deficiency;TFP deficiency;LC-FAOD; 344 Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;LC-FAOD;
162	Complement and coagulation cascades 💬	[1] SERPINC1 💬 Complement and coagulation cascades × Name Full Name SERPINC1 antithrombin-III isoform 1 precursor	Heparin calcium 💬 Complement and coagulation cascades × Name Other Names Heparin calcium Nadroparin calcium Calciparin Calciparine	Heparin	[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬 161. Complement and coagulation cascades × Disease ID Name 47 Buerger disease;Thromboangiitis obliterans; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 60 Aplastic anemia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 79 Homozygous familial hypercholesterolemia;Familial hypercholesterolemia;Familial hypercholesterolaemia; 84 Sarcoidosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 224 Purpura nephritis;Henoch-Schönlein purpura nephritis;HSPN; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation; 299 Cystic fibrosis;CF; 316 Carnitine cycle disorder;Disorders of carnitine transport and the carnitine cycle;Carnitine palmitoyltransferase I deficiency;CPT1 deficiency;Carnitine palmitoyltransferase II deficiency;CPT2 deficiency;LC-FAOD;Carnitine-acylcarnitine translocase deficiency;CACT deficiency;Primary Carnitine deficiency;OCTN2 deficiency; 317 Trifunctional protein deficiency;TFP deficiency;LC-FAOD; 344 Very long-chain acyl-CoA dehydrogenase deficiency;Very long-chain acyl-coenzyme A dehydrogenase deficiency;Very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency;VLCAD deficiency;VLCADD;LC-FAOD;
163	Cortisol synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cortisol synthesis and secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Cortisol synthesis and secretion × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 163. Cortisol synthesis and secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
164	Cortisol synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cortisol synthesis and secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Cortisol synthesis and secretion × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 163. Cortisol synthesis and secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
165	Cushing syndrome 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cushing syndrome × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Cushing syndrome × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 165. Cushing syndrome × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
166	Cushing syndrome 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cushing syndrome × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Cushing syndrome × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 165. Cushing syndrome × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
167	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 167. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
168	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 167. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
169	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 167. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
170	Cytokine-cytokine receptor interaction 💬	[1] EPOR 💬 Cytokine-cytokine receptor interaction × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Cytokine-cytokine receptor interaction × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 167. Cytokine-cytokine receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
171	Cytokine-cytokine receptor interaction 💬	[1] TNFSF11 💬 Cytokine-cytokine receptor interaction × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 Cytokine-cytokine receptor interaction × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 171. Cytokine-cytokine receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
172	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 beta-1 adrenergic receptor	Epinephrine 💬 Dilated cardiomyopathy × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 172. Dilated cardiomyopathy × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
173	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 beta-1 adrenergic receptor	Epinephrine hydrochloride 💬 Dilated cardiomyopathy × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 172. Dilated cardiomyopathy × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
174	Dilated cardiomyopathy 💬	[1] ADRB1 💬 Dilated cardiomyopathy × Name Full Name ADRB1 beta-1 adrenergic receptor	Epinephrine bitartrate 💬 Dilated cardiomyopathy × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 172. Dilated cardiomyopathy × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
175	Dilated cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Dilated cardiomyopathy × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Dilated cardiomyopathy × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 175. Dilated cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
176	Dilated cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Dilated cardiomyopathy × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Dilated cardiomyopathy × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 175. Dilated cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
177	Dilated cardiomyopathy 💬	[2] CACNA2D1, CACNA2D2 💬 Dilated cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor	Mirogabalin 💬 Dilated cardiomyopathy × Name Other Names Mirogabalin Mirogabalin	Mirogabalin	[1] 70 💬 177. Dilated cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
178	Dilated cardiomyopathy 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Dilated cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Gabapentin 💬 Dilated cardiomyopathy × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 178. Dilated cardiomyopathy × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
179	Dilated cardiomyopathy 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Dilated cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Pregabalin 💬 Dilated cardiomyopathy × Name Other Names Pregabalin Lyrica LYRICA CR PREGABALIN CAPSULES, CV PREGABALIN EXTENDED RELEASE PREGABLIN	Pregabalin	[5] 13, 36, 46, 70, 298 💬 179. Dilated cardiomyopathy × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
180	Dopaminergic synapse 💬	[2] ARRB1, ARRB2 💬 Dopaminergic synapse × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Dopaminergic synapse × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 180. Dopaminergic synapse × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
181	Dopaminergic synapse 💬	[2] CACNA1C, CACNA1D 💬 Dopaminergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Dopaminergic synapse × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 181. Dopaminergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
182	Dopaminergic synapse 💬	[2] CACNA1C, CACNA1D 💬 Dopaminergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Dopaminergic synapse × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 181. Dopaminergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
183	Dopaminergic synapse 💬	[2] GRIN2A, GRIN2B 💬 Dopaminergic synapse × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine 💬 Dopaminergic synapse × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 183. Dopaminergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
184	Dopaminergic synapse 💬	[2] GRIN2A, GRIN2B 💬 Dopaminergic synapse × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine hydrochloride 💬 Dopaminergic synapse × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 183. Dopaminergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
185	Dopaminergic synapse 💬	[2] GRIN2A, GRIN2B 💬 Dopaminergic synapse × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine hydrochloride 💬 Dopaminergic synapse × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 185. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
186	Dopaminergic synapse 💬	[2] GRIN2A, GRIN2B 💬 Dopaminergic synapse × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine 💬 Dopaminergic synapse × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 185. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
187	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Bupivacaine hydrochloride 💬 Dopaminergic synapse × Name Other Names Bupivacaine hydrochloride Bupivacaine hydrochloride hydrate Marcaine BUPIVACAINE HCL MARCAINE SPINAL SENSORCAINE BUPIVACAINE BUPIVACAINE HCI BUPIVACAINE HYDROCHLORIDE INJECTION, SOLUTION BUPIVACAINE HYDROCHLORIDE WITH DEXTROSE BUPIVICAINE HYDROCHLORIDE SENSORCAINE MPF	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 187. Dopaminergic synapse × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
188	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Bupivacaine 💬 Dopaminergic synapse × Name Other Names Bupivacaine Bucaine Exparel	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 187. Dopaminergic synapse × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
189	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Lidocaine 💬 Dopaminergic synapse × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 189. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
190	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Lidocaine hydrochloride 💬 Dopaminergic synapse × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 189. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
191	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Lidocaine hydrochloride monohydrate 💬 Dopaminergic synapse × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 189. Dopaminergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
192	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Ropivacaine hydrochloride 💬 Dopaminergic synapse × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 192. Dopaminergic synapse × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
193	Dopaminergic synapse 💬	[1] SCN1A 💬 Dopaminergic synapse × Name Full Name SCN1A sodium channel protein type 1 subunit alpha isoform 1	Ropivacaine 💬 Dopaminergic synapse × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 192. Dopaminergic synapse × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
194	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Efferocytosis × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 194. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
195	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Efferocytosis × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 194. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
196	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Efferocytosis × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 194. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
197	Efferocytosis 💬	[1] EPOR 💬 Efferocytosis × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Efferocytosis × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 194. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
198	Efferocytosis 💬	[2] PTGER2, PTGER4 💬 Efferocytosis × Name Full Name PTGER2 prostaglandin E2 receptor EP2 subtype PTGER4 prostaglandin E2 receptor EP4 subtype	Misoprostol 💬 Efferocytosis × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 198. Efferocytosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
199	Efferocytosis 💬	[1] PTGS2 💬 Efferocytosis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Efferocytosis × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 199. Efferocytosis × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
200	Efferocytosis 💬	[1] PTGS2 💬 Efferocytosis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Efferocytosis × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 200. Efferocytosis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
201	Efferocytosis 💬	[1] PTGS2 💬 Efferocytosis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Efferocytosis × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 201. Efferocytosis × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
202	Efferocytosis 💬	[1] PTGS2 💬 Efferocytosis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Efferocytosis × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 202. Efferocytosis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
203	Efferocytosis 💬	[1] PTGS2 💬 Efferocytosis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Efferocytosis × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 202. Efferocytosis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
204	Endocrine and other factor-regulated calcium reabsorption 💬	[1] PTH1R 💬 Endocrine and other factor-regulated calcium reabsorption × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Parathyroid hormone 💬 Endocrine and other factor-regulated calcium reabsorption × Name Other Names Parathyroid hormone ALX 1-11 Parathormone PTH Natpara	Parathyroid hormone	[2] 70, 235 💬 204. Endocrine and other factor-regulated calcium reabsorption × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease;
205	Endocrine and other factor-regulated calcium reabsorption 💬	[1] PTH1R 💬 Endocrine and other factor-regulated calcium reabsorption × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Endocrine and other factor-regulated calcium reabsorption × Name Other Names Teriparatide acetate Human PHT	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 205. Endocrine and other factor-regulated calcium reabsorption × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
206	Endocrine and other factor-regulated calcium reabsorption 💬	[1] PTH1R 💬 Endocrine and other factor-regulated calcium reabsorption × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide 💬 Endocrine and other factor-regulated calcium reabsorption × Name Other Names Teriparatide Forteo BONSITY	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 205. Endocrine and other factor-regulated calcium reabsorption × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
207	Endocrine and other factor-regulated calcium reabsorption 💬	[1] PTH1R 💬 Endocrine and other factor-regulated calcium reabsorption × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Endocrine and other factor-regulated calcium reabsorption × Name Other Names Teriparatide acetate Teriparatide acetate hydrate Parathar	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 205. Endocrine and other factor-regulated calcium reabsorption × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
208	Endocytosis 💬	[2] ARRB1, ARRB2 💬 Endocytosis × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Endocytosis × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 208. Endocytosis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
209	Estrogen signaling pathway 💬	[2] GABBR1, GABBR2 💬 Estrogen signaling pathway × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 Estrogen signaling pathway × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 209. Estrogen signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
210	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine hydrochloride 💬 Estrogen signaling pathway × Name Other Names Buprenorphine hydrochloride Buprenex BELBUCA BUPRENORPHINE BUPRENORPHINE HCL BUPRENORPHINE SUBLINGUAL BUPRENORPHINE SUBLINGUAL C-III	Buprenorphine	[3] 46, 70, 298 💬 210. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
211	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine 💬 Estrogen signaling pathway × Name Other Names Buprenorphine Temgesic BRIXADI BUTRANS SUBLOCADE BUPRENORPHINE TRANSDERMAL SYSTEM	Buprenorphine	[3] 46, 70, 298 💬 210. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
212	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl 💬 Estrogen signaling pathway × Name Other Names Fentanyl Duragesic Subsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 212. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
213	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl citrate 💬 Estrogen signaling pathway × Name Other Names Fentanyl citrate Abstral Fentora Lazanda Oralet	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 212. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
214	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl hydrochloride 💬 Estrogen signaling pathway × Name Other Names Fentanyl hydrochloride Ionsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 212. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
215	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone hydrochloride 💬 Estrogen signaling pathway × Name Other Names Hydromorphone hydrochloride Dilaudid Exalgo Palladone	Hydromorphone	[1] 70 💬 215. Estrogen signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
216	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone 💬 Estrogen signaling pathway × Name Other Names Hydromorphone Hydromorphone	Hydromorphone	[1] 70 💬 215. Estrogen signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
217	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine sulfate 💬 Estrogen signaling pathway × Name Other Names Morphine sulfate Morphine sulfate hydrate Morphine sulfate pentahydrate Astramor PH Avinza Depodur Kadian MS contin DURAMORPH MITIGO	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 217. Estrogen signaling pathway × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
218	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine hydrochloride hydrate 💬 Estrogen signaling pathway × Name Other Names Morphine hydrochloride hydrate Morphine hydrochloride trihydrate Anpec	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 217. Estrogen signaling pathway × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
219	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine 💬 Estrogen signaling pathway × Name Other Names Morphine Substitol	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 217. Estrogen signaling pathway × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
220	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine tartrate 💬 Estrogen signaling pathway × Name Other Names Morphine tartrate Morphine tartrate	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 217. Estrogen signaling pathway × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
221	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oliceridine 💬 Estrogen signaling pathway × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 221. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
222	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone hydrochloride 💬 Estrogen signaling pathway × Name Other Names Oxycodone hydrochloride Oxecta Oxycontin Roxicodone OXAYDO ROXYBOND OXYCODONE HCL OXYCODONE HYDCHLORIDE OXYCODONE HYDROCHLORIDE ORAL SOLUTION	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 222. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
223	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone terephthalate 💬 Estrogen signaling pathway × Name Other Names Oxycodone terephthalate Oxycodone terephthalate	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 222. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
224	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone 💬 Estrogen signaling pathway × Name Other Names Oxycodone XTAMPZA	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 222. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
225	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Estrogen signaling pathway × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 225. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
226	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Estrogen signaling pathway × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 225. Estrogen signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
227	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Estrogen signaling pathway × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 227. Estrogen signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
228	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Estrogen signaling pathway × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 227. Estrogen signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
229	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol hydrochloride 💬 Estrogen signaling pathway × Name Other Names Tramadol hydrochloride Ultram CONZIP TRAMADOL HCL TRAMADOL HCL ER	Tramadol	[4] 46, 70, 226, 271 💬 229. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
230	Estrogen signaling pathway 💬	[1] OPRM1 💬 Estrogen signaling pathway × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol 💬 Estrogen signaling pathway × Name Other Names Tramadol Amanda	Tramadol	[4] 46, 70, 226, 271 💬 229. Estrogen signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
231	Fluid shear stress and atherosclerosis 💬	[1] PLAT 💬 Fluid shear stress and atherosclerosis × Name Full Name PLAT tissue-type plasminogen activator isoform 1 preproprotein	Aminocaproic acid 💬 Fluid shear stress and atherosclerosis × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 231. Fluid shear stress and atherosclerosis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
232	GABAergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 GABAergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 GABAergic synapse × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 232. GABAergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
233	GABAergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 GABAergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 GABAergic synapse × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 232. GABAergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
234	GABAergic synapse 💬	[2] GABBR1, GABBR2 💬 GABAergic synapse × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 GABAergic synapse × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 234. GABAergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
235	GABAergic synapse 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam 💬 GABAergic synapse × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 235. GABAergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
236	GABAergic synapse 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam hydrochloride 💬 GABAergic synapse × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 235. GABAergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
237	GABAergic synapse 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam maleate 💬 GABAergic synapse × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 235. GABAergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
238	GABAergic synapse 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 GABAergic synapse × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 GABAergic synapse × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 238. GABAergic synapse × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
239	GABAergic synapse 💬	[1] SLC6A1 💬 GABAergic synapse × Name Full Name SLC6A1 sodium- and chloride-dependent GABA transporter 1 isoform a	Gabapentin 💬 GABAergic synapse × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 239. GABAergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
240	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 beta-1 adrenergic receptor	Epinephrine 💬 Gap junction × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 240. Gap junction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
241	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 beta-1 adrenergic receptor	Epinephrine hydrochloride 💬 Gap junction × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 240. Gap junction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
242	Gap junction 💬	[1] ADRB1 💬 Gap junction × Name Full Name ADRB1 beta-1 adrenergic receptor	Epinephrine bitartrate 💬 Gap junction × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 240. Gap junction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
243	Gastric acid secretion 💬	[1] CHRM3 💬 Gastric acid secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Rocuronium bromide 💬 Gastric acid secretion × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 243. Gastric acid secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
244	Glucagon signaling pathway 💬	[1] PDE3B 💬 Glucagon signaling pathway × Name Full Name PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Glucagon signaling pathway × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 244. Glucagon signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
245	Glutamatergic synapse 💬	[2] CACNA1C, CACNA1D 💬 Glutamatergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Glutamatergic synapse × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 245. Glutamatergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
246	Glutamatergic synapse 💬	[2] CACNA1C, CACNA1D 💬 Glutamatergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Glutamatergic synapse × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 245. Glutamatergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
247	Glutamatergic synapse 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Glutamatergic synapse × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Glutamatergic synapse × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 247. Glutamatergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
248	Glutamatergic synapse 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Glutamatergic synapse × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Glutamatergic synapse × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 247. Glutamatergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
249	Glutamatergic synapse 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Glutamatergic synapse × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Glutamatergic synapse × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 249. Glutamatergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
250	Glutamatergic synapse 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Glutamatergic synapse × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Glutamatergic synapse × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 249. Glutamatergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
251	GnRH secretion 💬	[2] ARRB1, ARRB2 💬 GnRH secretion × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 GnRH secretion × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 251. GnRH secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
252	GnRH secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 GnRH secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 GnRH secretion × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 252. GnRH secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
253	GnRH secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 GnRH secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 GnRH secretion × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 252. GnRH secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
254	GnRH secretion 💬	[2] GABBR1, GABBR2 💬 GnRH secretion × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 GnRH secretion × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 254. GnRH secretion × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
255	GnRH signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 GnRH signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 GnRH signaling pathway × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 255. GnRH signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
256	GnRH signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 GnRH signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 GnRH signaling pathway × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 255. GnRH signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
257	Growth hormone synthesis, secretion and action 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Growth hormone synthesis, secretion and action × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Growth hormone synthesis, secretion and action × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 257. Growth hormone synthesis, secretion and action × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
258	Growth hormone synthesis, secretion and action 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Growth hormone synthesis, secretion and action × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Growth hormone synthesis, secretion and action × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 257. Growth hormone synthesis, secretion and action × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
259	Hedgehog signaling pathway 💬	[2] ARRB1, ARRB2 💬 Hedgehog signaling pathway × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Hedgehog signaling pathway × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 259. Hedgehog signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
260	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Hematopoietic cell lineage × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 260. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
261	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Hematopoietic cell lineage × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 260. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
262	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Hematopoietic cell lineage × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 260. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
263	Hematopoietic cell lineage 💬	[1] EPOR 💬 Hematopoietic cell lineage × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Hematopoietic cell lineage × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 260. Hematopoietic cell lineage × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
264	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Hormone signaling × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 264. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
265	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Hormone signaling × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 264. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
266	Hormone signaling 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Hormone signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Hormone signaling × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 264. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
267	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine 💬 Hormone signaling × Name Other Names Clonidine Catarpres-TTS CLONIDINE TRANSDERMAL SYSTEM	Clonidine	[3]  6 , 65, 70 💬 267. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
268	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine hydrochloride 💬 Hormone signaling × Name Other Names Clonidine hydrochloride Nexiclon Kapvay Duraclon Catapres JAVADIN NEXICLON XR ONYDA XR QLONILIK CLONIDINE CLONIDINE HCI	Clonidine	[3]  6 , 65, 70 💬 267. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
269	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 Hormone signaling × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 269. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
270	Hormone signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Hormone signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 Hormone signaling × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 269. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
271	Hormone signaling 💬	[1] CALCR 💬 Hormone signaling × Name Full Name CALCR calcitonin receptor isoform 2 precursor	Elcatonin 💬 Hormone signaling × Name Other Names Elcatonin Adevirock	Elcatonin	[1] 70 💬 271. Hormone signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
272	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Hormone signaling × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 272. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
273	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Hormone signaling × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 272. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
274	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Hormone signaling × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 272. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
275	Hormone signaling 💬	[1] EPOR 💬 Hormone signaling × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Hormone signaling × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 272. Hormone signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
276	Hormone signaling 💬	[3] OPRD1, OPRK1, OPRM1 💬 Hormone signaling × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone hydrochloride 💬 Hormone signaling × Name Other Names Oxycodone hydrochloride Oxecta Oxycontin Roxicodone OXAYDO ROXYBOND OXYCODONE HCL OXYCODONE HYDCHLORIDE OXYCODONE HYDROCHLORIDE ORAL SOLUTION	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 276. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
277	Hormone signaling 💬	[3] OPRD1, OPRK1, OPRM1 💬 Hormone signaling × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone terephthalate 💬 Hormone signaling × Name Other Names Oxycodone terephthalate Oxycodone terephthalate	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 276. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
278	Hormone signaling 💬	[3] OPRD1, OPRK1, OPRM1 💬 Hormone signaling × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone 💬 Hormone signaling × Name Other Names Oxycodone XTAMPZA	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 276. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
279	Hormone signaling 💬	[2] OPRK1, OPRM1 💬 Hormone signaling × Name Full Name OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine hydrochloride 💬 Hormone signaling × Name Other Names Buprenorphine hydrochloride Buprenex BELBUCA BUPRENORPHINE BUPRENORPHINE HCL BUPRENORPHINE SUBLINGUAL BUPRENORPHINE SUBLINGUAL C-III	Buprenorphine	[3] 46, 70, 298 💬 279. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
280	Hormone signaling 💬	[2] OPRK1, OPRM1 💬 Hormone signaling × Name Full Name OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine 💬 Hormone signaling × Name Other Names Buprenorphine Temgesic BRIXADI BUTRANS SUBLOCADE BUPRENORPHINE TRANSDERMAL SYSTEM	Buprenorphine	[3] 46, 70, 298 💬 279. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
281	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl 💬 Hormone signaling × Name Other Names Fentanyl Duragesic Subsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 281. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
282	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl citrate 💬 Hormone signaling × Name Other Names Fentanyl citrate Abstral Fentora Lazanda Oralet	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 281. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
283	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl hydrochloride 💬 Hormone signaling × Name Other Names Fentanyl hydrochloride Ionsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 281. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
284	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone hydrochloride 💬 Hormone signaling × Name Other Names Hydromorphone hydrochloride Dilaudid Exalgo Palladone	Hydromorphone	[1] 70 💬 284. Hormone signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
285	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone 💬 Hormone signaling × Name Other Names Hydromorphone Hydromorphone	Hydromorphone	[1] 70 💬 284. Hormone signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
286	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine sulfate 💬 Hormone signaling × Name Other Names Morphine sulfate Morphine sulfate hydrate Morphine sulfate pentahydrate Astramor PH Avinza Depodur Kadian MS contin DURAMORPH MITIGO	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 286. Hormone signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
287	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine hydrochloride hydrate 💬 Hormone signaling × Name Other Names Morphine hydrochloride hydrate Morphine hydrochloride trihydrate Anpec	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 286. Hormone signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
288	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine 💬 Hormone signaling × Name Other Names Morphine Substitol	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 286. Hormone signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
289	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine tartrate 💬 Hormone signaling × Name Other Names Morphine tartrate Morphine tartrate	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 286. Hormone signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
290	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oliceridine 💬 Hormone signaling × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 290. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
291	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Hormone signaling × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 291. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
292	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Hormone signaling × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 291. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
293	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Hormone signaling × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 293. Hormone signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
294	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Hormone signaling × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 293. Hormone signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
295	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol hydrochloride 💬 Hormone signaling × Name Other Names Tramadol hydrochloride Ultram CONZIP TRAMADOL HCL TRAMADOL HCL ER	Tramadol	[4] 46, 70, 226, 271 💬 295. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
296	Hormone signaling 💬	[1] OPRM1 💬 Hormone signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol 💬 Hormone signaling × Name Other Names Tramadol Amanda	Tramadol	[4] 46, 70, 226, 271 💬 295. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
297	Hormone signaling 💬	[1] OXTR 💬 Hormone signaling × Name Full Name OXTR oxytocin receptor	Oxytocin 💬 Hormone signaling × Name Other Names Oxytocin Pitocin Syntocinon	Oxytocin	[8]  6 , 70, 72, 127, 168, 193, 206, 226 💬 297. Hormone signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 127 Frontotemporal lobar degeneration;Frontotemporal dementia, behavioral abnormal type;Frontotemporal dementia;Semantic dementia; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 193 Prader-Willi syndrome; 206 Fragile X syndrome; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
298	Hormone signaling 💬	[1] PTH1R 💬 Hormone signaling × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Parathyroid hormone 💬 Hormone signaling × Name Other Names Parathyroid hormone ALX 1-11 Parathormone PTH Natpara	Parathyroid hormone	[2] 70, 235 💬 298. Hormone signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease;
299	Hormone signaling 💬	[1] PTH1R 💬 Hormone signaling × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Hormone signaling × Name Other Names Teriparatide acetate Human PHT	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 299. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
300	Hormone signaling 💬	[1] PTH1R 💬 Hormone signaling × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide 💬 Hormone signaling × Name Other Names Teriparatide Forteo BONSITY	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 299. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
301	Hormone signaling 💬	[1] PTH1R 💬 Hormone signaling × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Hormone signaling × Name Other Names Teriparatide acetate Teriparatide acetate hydrate Parathar	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 299. Hormone signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
302	Human cytomegalovirus infection 💬	[1] PTGER1 💬 Human cytomegalovirus infection × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Alprostadil 💬 Human cytomegalovirus infection × Name Other Names Alprostadil Prostin VR pediatric Caverject Edex Muse CAVERJECT IMPULSE PROSTIN	Alprostadil	[2] 51, 70 💬 302. Human cytomegalovirus infection × Disease ID Name 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis;
303	Human cytomegalovirus infection 💬	[1] PTGER1 💬 Human cytomegalovirus infection × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost 💬 Human cytomegalovirus infection × Name Other Names Limaprost Limaprost	Limaprost	[1] 70 💬 303. Human cytomegalovirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
304	Human cytomegalovirus infection 💬	[1] PTGER1 💬 Human cytomegalovirus infection × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost alfadex 💬 Human cytomegalovirus infection × Name Other Names Limaprost alfadex Opalmon	Limaprost	[1] 70 💬 303. Human cytomegalovirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
305	Human cytomegalovirus infection 💬	[3] PTGER2, PTGER3, PTGER4 💬 Human cytomegalovirus infection × Name Full Name PTGER2 prostaglandin E2 receptor EP2 subtype PTGER3 prostaglandin E2 receptor EP3 subtype isoform 4 PTGER4 prostaglandin E2 receptor EP4 subtype	Misoprostol 💬 Human cytomegalovirus infection × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 305. Human cytomegalovirus infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
306	Human cytomegalovirus infection 💬	[1] PTGS2 💬 Human cytomegalovirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Human cytomegalovirus infection × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 306. Human cytomegalovirus infection × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
307	Human cytomegalovirus infection 💬	[1] PTGS2 💬 Human cytomegalovirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Human cytomegalovirus infection × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 307. Human cytomegalovirus infection × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
308	Human cytomegalovirus infection 💬	[1] PTGS2 💬 Human cytomegalovirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Human cytomegalovirus infection × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 308. Human cytomegalovirus infection × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
309	Human cytomegalovirus infection 💬	[1] PTGS2 💬 Human cytomegalovirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Human cytomegalovirus infection × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 309. Human cytomegalovirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
310	Human cytomegalovirus infection 💬	[1] PTGS2 💬 Human cytomegalovirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Human cytomegalovirus infection × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 309. Human cytomegalovirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
311	Human papillomavirus infection 💬	[1] PTGER4 💬 Human papillomavirus infection × Name Full Name PTGER4 prostaglandin E2 receptor EP4 subtype	Misoprostol 💬 Human papillomavirus infection × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 311. Human papillomavirus infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
312	Human papillomavirus infection 💬	[1] PTGS2 💬 Human papillomavirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Human papillomavirus infection × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 312. Human papillomavirus infection × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
313	Human papillomavirus infection 💬	[1] PTGS2 💬 Human papillomavirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Human papillomavirus infection × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 313. Human papillomavirus infection × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
314	Human papillomavirus infection 💬	[1] PTGS2 💬 Human papillomavirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Human papillomavirus infection × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 314. Human papillomavirus infection × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
315	Human papillomavirus infection 💬	[1] PTGS2 💬 Human papillomavirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Human papillomavirus infection × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 315. Human papillomavirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
316	Human papillomavirus infection 💬	[1] PTGS2 💬 Human papillomavirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Human papillomavirus infection × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 315. Human papillomavirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
317	Huntington disease 💬	[2] GRIN1, GRIN2B 💬 Huntington disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine 💬 Huntington disease × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 317. Huntington disease × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
318	Huntington disease 💬	[2] GRIN1, GRIN2B 💬 Huntington disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine hydrochloride 💬 Huntington disease × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 317. Huntington disease × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
319	Huntington disease 💬	[2] GRIN1, GRIN2B 💬 Huntington disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine hydrochloride 💬 Huntington disease × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 319. Huntington disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
320	Huntington disease 💬	[2] GRIN1, GRIN2B 💬 Huntington disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine 💬 Huntington disease × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 319. Huntington disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
321	Hypertrophic cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Hypertrophic cardiomyopathy × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Hypertrophic cardiomyopathy × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 321. Hypertrophic cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
322	Hypertrophic cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Hypertrophic cardiomyopathy × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Hypertrophic cardiomyopathy × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 321. Hypertrophic cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
323	Hypertrophic cardiomyopathy 💬	[2] CACNA2D1, CACNA2D2 💬 Hypertrophic cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor	Mirogabalin 💬 Hypertrophic cardiomyopathy × Name Other Names Mirogabalin Mirogabalin	Mirogabalin	[1] 70 💬 323. Hypertrophic cardiomyopathy × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
324	Hypertrophic cardiomyopathy 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Hypertrophic cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Gabapentin 💬 Hypertrophic cardiomyopathy × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 324. Hypertrophic cardiomyopathy × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
325	Hypertrophic cardiomyopathy 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Hypertrophic cardiomyopathy × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Pregabalin 💬 Hypertrophic cardiomyopathy × Name Other Names Pregabalin Lyrica LYRICA CR PREGABALIN CAPSULES, CV PREGABALIN EXTENDED RELEASE PREGABLIN	Pregabalin	[5] 13, 36, 46, 70, 298 💬 325. Hypertrophic cardiomyopathy × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
326	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Bupivacaine hydrochloride 💬 IgSF CAM signaling × Name Other Names Bupivacaine hydrochloride Bupivacaine hydrochloride hydrate Marcaine BUPIVACAINE HCL MARCAINE SPINAL SENSORCAINE BUPIVACAINE BUPIVACAINE HCI BUPIVACAINE HYDROCHLORIDE INJECTION, SOLUTION BUPIVACAINE HYDROCHLORIDE WITH DEXTROSE BUPIVICAINE HYDROCHLORIDE SENSORCAINE MPF	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 326. IgSF CAM signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
327	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Bupivacaine 💬 IgSF CAM signaling × Name Other Names Bupivacaine Bucaine Exparel	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 326. IgSF CAM signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
328	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Lidocaine 💬 IgSF CAM signaling × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 328. IgSF CAM signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
329	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Lidocaine hydrochloride 💬 IgSF CAM signaling × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 328. IgSF CAM signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
330	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Lidocaine hydrochloride monohydrate 💬 IgSF CAM signaling × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 328. IgSF CAM signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
331	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Ropivacaine hydrochloride 💬 IgSF CAM signaling × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 331. IgSF CAM signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
332	IgSF CAM signaling 💬	[1] SCN8A 💬 IgSF CAM signaling × Name Full Name SCN8A sodium channel protein type 8 subunit alpha isoform 3	Ropivacaine 💬 IgSF CAM signaling × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 331. IgSF CAM signaling × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
333	IL-17 signaling pathway 💬	[1] PTGS2 💬 IL-17 signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 IL-17 signaling pathway × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 333. IL-17 signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
334	IL-17 signaling pathway 💬	[1] PTGS2 💬 IL-17 signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 IL-17 signaling pathway × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 334. IL-17 signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
335	IL-17 signaling pathway 💬	[1] PTGS2 💬 IL-17 signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 IL-17 signaling pathway × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 335. IL-17 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
336	IL-17 signaling pathway 💬	[1] PTGS2 💬 IL-17 signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 IL-17 signaling pathway × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 336. IL-17 signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
337	IL-17 signaling pathway 💬	[1] PTGS2 💬 IL-17 signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 IL-17 signaling pathway × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 336. IL-17 signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
338	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬 Inflammatory mediator regulation of TRP channels × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine 💬 Inflammatory mediator regulation of TRP channels × Name Other Names Diphenhydramine Restamin	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 338. Inflammatory mediator regulation of TRP channels × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
339	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬 Inflammatory mediator regulation of TRP channels × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine hydrochloride 💬 Inflammatory mediator regulation of TRP channels × Name Other Names Diphenhydramine hydrochloride Benadryl	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 338. Inflammatory mediator regulation of TRP channels × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
340	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬 Inflammatory mediator regulation of TRP channels × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine salicylate 💬 Inflammatory mediator regulation of TRP channels × Name Other Names Diphenhydramine salicylate Diphenhydramine salicylate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 338. Inflammatory mediator regulation of TRP channels × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
341	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬 Inflammatory mediator regulation of TRP channels × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine citrate 💬 Inflammatory mediator regulation of TRP channels × Name Other Names Diphenhydramine citrate Diphenhydramine citrate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 338. Inflammatory mediator regulation of TRP channels × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
342	Inflammatory mediator regulation of TRP channels 💬	[2] PTGER2, PTGER4 💬 Inflammatory mediator regulation of TRP channels × Name Full Name PTGER2 prostaglandin E2 receptor EP2 subtype PTGER4 prostaglandin E2 receptor EP4 subtype	Misoprostol 💬 Inflammatory mediator regulation of TRP channels × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 342. Inflammatory mediator regulation of TRP channels × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
343	Influenza A 💬	[1] PLG 💬 Influenza A × Name Full Name PLG plasminogen isoform 1 precursor	Aminocaproic acid 💬 Influenza A × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 343. Influenza A × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
344	Influenza A 💬	[1] PLG 💬 Influenza A × Name Full Name PLG plasminogen isoform 1 precursor	Tranexamic acid 💬 Influenza A × Name Other Names Tranexamic acid Cyklokapron Rikavarin Transamin TRANEXAMIC ACID IN SODIUM CHLORIDE	Tranexamic acid	[7] 46, 65, 70, 215, 227, 274, 299 💬 344. Influenza A × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 215 Tetralogy of Fallot;Fallot tetralogy; 227 Osler disease;Hereditary hemorrhagic telangiectasia;HHT;Osler-Weber-Rendu disease; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
345	Influenza A 💬	[3] PRSS1, PRSS2, PRSS3 💬 Influenza A × Name Full Name PRSS1 serine protease 1 preproprotein PRSS2 trypsin-2 isoform 2 preproprotein PRSS3 trypsin-3 isoform 3 preproprotein	Ulinastatin 💬 Influenza A × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 345. Influenza A × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
346	Insulin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Insulin secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Insulin secretion × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 346. Insulin secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
347	Insulin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Insulin secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Insulin secretion × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 346. Insulin secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
348	Insulin secretion 💬	[1] CHRM3 💬 Insulin secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Rocuronium bromide 💬 Insulin secretion × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 348. Insulin secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
349	Insulin secretion 💬	[1] SNAP25 💬 Insulin secretion × Name Full Name SNAP25 synaptosomal-associated protein 25 isoform SNAP25A	Botulinum toxin type A 💬 Insulin secretion × Name Other Names Botulinum toxin type A Botox Dysport DAXXIFY	Botulinum toxin type A	[13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬 349. Insulin secretion × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  5  Progressive supranuclear palsy;PSP;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 15 Inclusion body myositis; 17 Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome; 47 Buerger disease;Thromboangiitis obliterans; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 171 Wilson disease;WD; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
350	Insulin secretion 💬	[1] SNAP25 💬 Insulin secretion × Name Full Name SNAP25 synaptosomal-associated protein 25 isoform SNAP25A	Incobotulinumtoxin A 💬 Insulin secretion × Name Other Names Incobotulinumtoxin A Onaclostox Xeomin	Botulinum toxin type A	[13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬 349. Insulin secretion × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  5  Progressive supranuclear palsy;PSP;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 15 Inclusion body myositis; 17 Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome; 47 Buerger disease;Thromboangiitis obliterans; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 171 Wilson disease;WD; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
351	Insulin signaling pathway 💬	[1] PDE3B 💬 Insulin signaling pathway × Name Full Name PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Insulin signaling pathway × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 351. Insulin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
352	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 JAK-STAT signaling pathway × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 352. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
353	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 JAK-STAT signaling pathway × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 352. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
354	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 JAK-STAT signaling pathway × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 352. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
355	JAK-STAT signaling pathway 💬	[1] EPOR 💬 JAK-STAT signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 JAK-STAT signaling pathway × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 352. JAK-STAT signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
356	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬 Kaposi sarcoma-associated herpesvirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 356. Kaposi sarcoma-associated herpesvirus infection × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
357	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬 Kaposi sarcoma-associated herpesvirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 357. Kaposi sarcoma-associated herpesvirus infection × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
358	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬 Kaposi sarcoma-associated herpesvirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 358. Kaposi sarcoma-associated herpesvirus infection × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
359	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬 Kaposi sarcoma-associated herpesvirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 359. Kaposi sarcoma-associated herpesvirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
360	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬 Kaposi sarcoma-associated herpesvirus infection × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Kaposi sarcoma-associated herpesvirus infection × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 359. Kaposi sarcoma-associated herpesvirus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
361	Leishmaniasis 💬	[1] PTGS2 💬 Leishmaniasis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Leishmaniasis × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 361. Leishmaniasis × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
362	Leishmaniasis 💬	[1] PTGS2 💬 Leishmaniasis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Leishmaniasis × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 362. Leishmaniasis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
363	Leishmaniasis 💬	[1] PTGS2 💬 Leishmaniasis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Leishmaniasis × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 363. Leishmaniasis × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
364	Leishmaniasis 💬	[1] PTGS2 💬 Leishmaniasis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Leishmaniasis × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 364. Leishmaniasis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
365	Leishmaniasis 💬	[1] PTGS2 💬 Leishmaniasis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Leishmaniasis × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 364. Leishmaniasis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
366	Long-term potentiation 💬	[1] CACNA1C 💬 Long-term potentiation × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18	Nicardipine hydrochloride 💬 Long-term potentiation × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 366. Long-term potentiation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
367	Long-term potentiation 💬	[1] CACNA1C 💬 Long-term potentiation × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18	Nicardipine 💬 Long-term potentiation × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 366. Long-term potentiation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
368	Long-term potentiation 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Long-term potentiation × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Long-term potentiation × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 368. Long-term potentiation × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
369	Long-term potentiation 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Long-term potentiation × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Long-term potentiation × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 368. Long-term potentiation × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
370	Long-term potentiation 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Long-term potentiation × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Long-term potentiation × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 370. Long-term potentiation × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
371	Long-term potentiation 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Long-term potentiation × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Long-term potentiation × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 370. Long-term potentiation × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
372	MAPK signaling pathway 💬	[2] ARRB1, ARRB2 💬 MAPK signaling pathway × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 MAPK signaling pathway × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 372. MAPK signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
373	MAPK signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 MAPK signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 MAPK signaling pathway × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 373. MAPK signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
374	MAPK signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 MAPK signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 MAPK signaling pathway × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 373. MAPK signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
375	MAPK signaling pathway 💬	[2] CACNA2D1, CACNA2D2 💬 MAPK signaling pathway × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor	Mirogabalin 💬 MAPK signaling pathway × Name Other Names Mirogabalin Mirogabalin	Mirogabalin	[1] 70 💬 375. MAPK signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
376	MAPK signaling pathway 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 MAPK signaling pathway × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Gabapentin 💬 MAPK signaling pathway × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 376. MAPK signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
377	MAPK signaling pathway 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 MAPK signaling pathway × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Pregabalin 💬 MAPK signaling pathway × Name Other Names Pregabalin Lyrica LYRICA CR PREGABALIN CAPSULES, CV PREGABALIN EXTENDED RELEASE PREGABLIN	Pregabalin	[5] 13, 36, 46, 70, 298 💬 377. MAPK signaling pathway × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
378	MicroRNAs in cancer 💬	[1] PTGS2 💬 MicroRNAs in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 MicroRNAs in cancer × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 378. MicroRNAs in cancer × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
379	MicroRNAs in cancer 💬	[1] PTGS2 💬 MicroRNAs in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 MicroRNAs in cancer × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 379. MicroRNAs in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
380	MicroRNAs in cancer 💬	[1] PTGS2 💬 MicroRNAs in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 MicroRNAs in cancer × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 380. MicroRNAs in cancer × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
381	MicroRNAs in cancer 💬	[1] PTGS2 💬 MicroRNAs in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 MicroRNAs in cancer × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 381. MicroRNAs in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
382	MicroRNAs in cancer 💬	[1] PTGS2 💬 MicroRNAs in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 MicroRNAs in cancer × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 381. MicroRNAs in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
383	Morphine addiction 💬	[3] ARRB1, ARRB2, OPRM1 💬 Morphine addiction × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oliceridine 💬 Morphine addiction × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 383. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
384	Morphine addiction 💬	[2] GABBR1, GABBR2 💬 Morphine addiction × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 Morphine addiction × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 384. Morphine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
385	Morphine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam 💬 Morphine addiction × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 385. Morphine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
386	Morphine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam hydrochloride 💬 Morphine addiction × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 385. Morphine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
387	Morphine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam maleate 💬 Morphine addiction × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 385. Morphine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
388	Morphine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Morphine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Morphine addiction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 388. Morphine addiction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
389	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine hydrochloride 💬 Morphine addiction × Name Other Names Buprenorphine hydrochloride Buprenex BELBUCA BUPRENORPHINE BUPRENORPHINE HCL BUPRENORPHINE SUBLINGUAL BUPRENORPHINE SUBLINGUAL C-III	Buprenorphine	[3] 46, 70, 298 💬 389. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
390	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine 💬 Morphine addiction × Name Other Names Buprenorphine Temgesic BRIXADI BUTRANS SUBLOCADE BUPRENORPHINE TRANSDERMAL SYSTEM	Buprenorphine	[3] 46, 70, 298 💬 389. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
391	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl 💬 Morphine addiction × Name Other Names Fentanyl Duragesic Subsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 391. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
392	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl citrate 💬 Morphine addiction × Name Other Names Fentanyl citrate Abstral Fentora Lazanda Oralet	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 391. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
393	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl hydrochloride 💬 Morphine addiction × Name Other Names Fentanyl hydrochloride Ionsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 391. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
394	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone hydrochloride 💬 Morphine addiction × Name Other Names Hydromorphone hydrochloride Dilaudid Exalgo Palladone	Hydromorphone	[1] 70 💬 394. Morphine addiction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
395	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone 💬 Morphine addiction × Name Other Names Hydromorphone Hydromorphone	Hydromorphone	[1] 70 💬 394. Morphine addiction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
396	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine sulfate 💬 Morphine addiction × Name Other Names Morphine sulfate Morphine sulfate hydrate Morphine sulfate pentahydrate Astramor PH Avinza Depodur Kadian MS contin DURAMORPH MITIGO	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 396. Morphine addiction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
397	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine hydrochloride hydrate 💬 Morphine addiction × Name Other Names Morphine hydrochloride hydrate Morphine hydrochloride trihydrate Anpec	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 396. Morphine addiction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
398	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine 💬 Morphine addiction × Name Other Names Morphine Substitol	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 396. Morphine addiction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
399	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine tartrate 💬 Morphine addiction × Name Other Names Morphine tartrate Morphine tartrate	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 396. Morphine addiction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
400	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone hydrochloride 💬 Morphine addiction × Name Other Names Oxycodone hydrochloride Oxecta Oxycontin Roxicodone OXAYDO ROXYBOND OXYCODONE HCL OXYCODONE HYDCHLORIDE OXYCODONE HYDROCHLORIDE ORAL SOLUTION	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 400. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
401	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone terephthalate 💬 Morphine addiction × Name Other Names Oxycodone terephthalate Oxycodone terephthalate	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 400. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
402	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone 💬 Morphine addiction × Name Other Names Oxycodone XTAMPZA	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 400. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
403	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Morphine addiction × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 403. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
404	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Morphine addiction × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 403. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
405	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Morphine addiction × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 405. Morphine addiction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
406	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Morphine addiction × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 405. Morphine addiction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
407	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol hydrochloride 💬 Morphine addiction × Name Other Names Tramadol hydrochloride Ultram CONZIP TRAMADOL HCL TRAMADOL HCL ER	Tramadol	[4] 46, 70, 226, 271 💬 407. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
408	Morphine addiction 💬	[1] OPRM1 💬 Morphine addiction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol 💬 Morphine addiction × Name Other Names Tramadol Amanda	Tramadol	[4] 46, 70, 226, 271 💬 407. Morphine addiction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
409	Morphine addiction 💬	[2] PDE3A, PDE3B 💬 Morphine addiction × Name Full Name PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform 1 PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Morphine addiction × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 409. Morphine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
410	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine 💬 Neuroactive ligand signaling × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 410. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
411	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 410. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
412	Neuroactive ligand signaling 💬	[8] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2 💬 Neuroactive ligand signaling × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor	Epinephrine bitartrate 💬 Neuroactive ligand signaling × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 410. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
413	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine 💬 Neuroactive ligand signaling × Name Other Names Clonidine Catarpres-TTS CLONIDINE TRANSDERMAL SYSTEM	Clonidine	[3]  6 , 65, 70 💬 413. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
414	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Clonidine hydrochloride Nexiclon Kapvay Duraclon Catapres JAVADIN NEXICLON XR ONYDA XR QLONILIK CLONIDINE CLONIDINE HCI	Clonidine	[3]  6 , 65, 70 💬 413. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
415	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 Neuroactive ligand signaling × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 415. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
416	Neuroactive ligand signaling 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand signaling × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 415. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
417	Neuroactive ligand signaling 💬	[11] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 Neuroactive ligand signaling × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5 CHRNA3 neuronal acetylcholine receptor subunit alpha-3 isoform 1 precursor CHRNA4 neuronal acetylcholine receptor subunit alpha-4 isoform 1 precursor CHRNA6 neuronal acetylcholine receptor subunit alpha-6 isoform 1 precursor CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor CHRNB2 neuronal acetylcholine receptor subunit beta-2 precursor CHRNB4 neuronal acetylcholine receptor subunit beta-4 isoform 1 precursor	Rocuronium bromide 💬 Neuroactive ligand signaling × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 417. Neuroactive ligand signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
418	Neuroactive ligand signaling 💬	[2] GABBR1, GABBR2 💬 Neuroactive ligand signaling × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 Neuroactive ligand signaling × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 418. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
419	Neuroactive ligand signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam 💬 Neuroactive ligand signaling × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 419. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
420	Neuroactive ligand signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 419. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
421	Neuroactive ligand signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam maleate 💬 Neuroactive ligand signaling × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 419. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
422	Neuroactive ligand signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Neuroactive ligand signaling × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 422. Neuroactive ligand signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
423	Neuroactive ligand signaling 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand signaling × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Neuroactive ligand signaling × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 423. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
424	Neuroactive ligand signaling 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand signaling × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 423. Neuroactive ligand signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
425	Neuroactive ligand signaling 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand signaling × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 425. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
426	Neuroactive ligand signaling 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand signaling × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Neuroactive ligand signaling × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 425. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
427	Neuroactive ligand signaling 💬	[1] HRH1 💬 Neuroactive ligand signaling × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine 💬 Neuroactive ligand signaling × Name Other Names Diphenhydramine Restamin	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 427. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
428	Neuroactive ligand signaling 💬	[1] HRH1 💬 Neuroactive ligand signaling × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Diphenhydramine hydrochloride Benadryl	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 427. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
429	Neuroactive ligand signaling 💬	[1] HRH1 💬 Neuroactive ligand signaling × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine salicylate 💬 Neuroactive ligand signaling × Name Other Names Diphenhydramine salicylate Diphenhydramine salicylate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 427. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
430	Neuroactive ligand signaling 💬	[1] HRH1 💬 Neuroactive ligand signaling × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine citrate 💬 Neuroactive ligand signaling × Name Other Names Diphenhydramine citrate Diphenhydramine citrate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 427. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
431	Neuroactive ligand signaling 💬	[3] OPRD1, OPRK1, OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Oxycodone hydrochloride Oxecta Oxycontin Roxicodone OXAYDO ROXYBOND OXYCODONE HCL OXYCODONE HYDCHLORIDE OXYCODONE HYDROCHLORIDE ORAL SOLUTION	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 431. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
432	Neuroactive ligand signaling 💬	[3] OPRD1, OPRK1, OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone terephthalate 💬 Neuroactive ligand signaling × Name Other Names Oxycodone terephthalate Oxycodone terephthalate	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 431. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
433	Neuroactive ligand signaling 💬	[3] OPRD1, OPRK1, OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone 💬 Neuroactive ligand signaling × Name Other Names Oxycodone XTAMPZA	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 431. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
434	Neuroactive ligand signaling 💬	[2] OPRK1, OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Buprenorphine hydrochloride Buprenex BELBUCA BUPRENORPHINE BUPRENORPHINE HCL BUPRENORPHINE SUBLINGUAL BUPRENORPHINE SUBLINGUAL C-III	Buprenorphine	[3] 46, 70, 298 💬 434. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
435	Neuroactive ligand signaling 💬	[2] OPRK1, OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine 💬 Neuroactive ligand signaling × Name Other Names Buprenorphine Temgesic BRIXADI BUTRANS SUBLOCADE BUPRENORPHINE TRANSDERMAL SYSTEM	Buprenorphine	[3] 46, 70, 298 💬 434. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
436	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl 💬 Neuroactive ligand signaling × Name Other Names Fentanyl Duragesic Subsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 436. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
437	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl citrate 💬 Neuroactive ligand signaling × Name Other Names Fentanyl citrate Abstral Fentora Lazanda Oralet	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 436. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
438	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Fentanyl hydrochloride Ionsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 436. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
439	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Hydromorphone hydrochloride Dilaudid Exalgo Palladone	Hydromorphone	[1] 70 💬 439. Neuroactive ligand signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
440	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone 💬 Neuroactive ligand signaling × Name Other Names Hydromorphone Hydromorphone	Hydromorphone	[1] 70 💬 439. Neuroactive ligand signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
441	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine sulfate 💬 Neuroactive ligand signaling × Name Other Names Morphine sulfate Morphine sulfate hydrate Morphine sulfate pentahydrate Astramor PH Avinza Depodur Kadian MS contin DURAMORPH MITIGO	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 441. Neuroactive ligand signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
442	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine hydrochloride hydrate 💬 Neuroactive ligand signaling × Name Other Names Morphine hydrochloride hydrate Morphine hydrochloride trihydrate Anpec	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 441. Neuroactive ligand signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
443	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine 💬 Neuroactive ligand signaling × Name Other Names Morphine Substitol	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 441. Neuroactive ligand signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
444	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine tartrate 💬 Neuroactive ligand signaling × Name Other Names Morphine tartrate Morphine tartrate	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 441. Neuroactive ligand signaling × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
445	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oliceridine 💬 Neuroactive ligand signaling × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 445. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
446	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 446. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
447	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Neuroactive ligand signaling × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 446. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
448	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Neuroactive ligand signaling × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 448. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
449	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Neuroactive ligand signaling × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 448. Neuroactive ligand signaling × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
450	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol hydrochloride 💬 Neuroactive ligand signaling × Name Other Names Tramadol hydrochloride Ultram CONZIP TRAMADOL HCL TRAMADOL HCL ER	Tramadol	[4] 46, 70, 226, 271 💬 450. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
451	Neuroactive ligand signaling 💬	[1] OPRM1 💬 Neuroactive ligand signaling × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol 💬 Neuroactive ligand signaling × Name Other Names Tramadol Amanda	Tramadol	[4] 46, 70, 226, 271 💬 450. Neuroactive ligand signaling × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
452	Neuroactive ligand signaling 💬	[1] SLC6A1 💬 Neuroactive ligand signaling × Name Full Name SLC6A1 sodium- and chloride-dependent GABA transporter 1 isoform a	Gabapentin 💬 Neuroactive ligand signaling × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 452. Neuroactive ligand signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
453	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Neuroactive ligand-receptor interaction × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 453. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
454	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 453. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
455	Neuroactive ligand-receptor interaction 💬	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 453. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
456	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine 💬 Neuroactive ligand-receptor interaction × Name Other Names Clonidine Catarpres-TTS CLONIDINE TRANSDERMAL SYSTEM	Clonidine	[3]  6 , 65, 70 💬 456. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
457	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Clonidine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Clonidine hydrochloride Nexiclon Kapvay Duraclon Catapres JAVADIN NEXICLON XR ONYDA XR QLONILIK CLONIDINE CLONIDINE HCI	Clonidine	[3]  6 , 65, 70 💬 456. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis;
458	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexmedetomidine Dexdor Precedex	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 458. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
459	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬 Neuroactive ligand-receptor interaction × Name Full Name ADRA2A alpha-2A adrenergic receptor ADRA2B alpha-2B adrenergic receptor ADRA2C alpha-2C adrenergic receptor	Dexmedetomidine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexmedetomidine hydrochloride Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE	Dexmedetomidine	[15]  2 ,  4 ,  6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 458. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 171 Wilson disease;WD; 212 Tricuspid atresia;TA; 215 Tetralogy of Fallot;Fallot tetralogy; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
460	Neuroactive ligand-receptor interaction 💬	[1] CALCR 💬 Neuroactive ligand-receptor interaction × Name Full Name CALCR calcitonin receptor isoform 2 precursor	Elcatonin 💬 Neuroactive ligand-receptor interaction × Name Other Names Elcatonin Adevirock	Elcatonin	[1] 70 💬 460. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
461	Neuroactive ligand-receptor interaction 💬	[16] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB2, CHRNB3, CHRNB4 💬 Neuroactive ligand-receptor interaction × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5 CHRNA10 neuronal acetylcholine receptor subunit alpha-10 isoform a precursor CHRNA2 neuronal acetylcholine receptor subunit alpha-2 isoform 1 precursor CHRNA3 neuronal acetylcholine receptor subunit alpha-3 isoform 1 precursor CHRNA4 neuronal acetylcholine receptor subunit alpha-4 isoform 1 precursor CHRNA5 neuronal acetylcholine receptor subunit alpha-5 isoform 1 precursor CHRNA6 neuronal acetylcholine receptor subunit alpha-6 isoform 1 precursor CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor CHRNA9 neuronal acetylcholine receptor subunit alpha-9 precursor CHRNB2 neuronal acetylcholine receptor subunit beta-2 precursor CHRNB3 neuronal acetylcholine receptor subunit beta-3 isoform 1 precursor CHRNB4 neuronal acetylcholine receptor subunit beta-4 isoform 1 precursor	Rocuronium bromide 💬 Neuroactive ligand-receptor interaction × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 461. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
462	Neuroactive ligand-receptor interaction 💬	[2] GABBR1, GABBR2 💬 Neuroactive ligand-receptor interaction × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 Neuroactive ligand-receptor interaction × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 462. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
463	Neuroactive ligand-receptor interaction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam 💬 Neuroactive ligand-receptor interaction × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 463. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
464	Neuroactive ligand-receptor interaction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 463. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
465	Neuroactive ligand-receptor interaction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam maleate 💬 Neuroactive ligand-receptor interaction × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 463. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
466	Neuroactive ligand-receptor interaction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Neuroactive ligand-receptor interaction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Neuroactive ligand-receptor interaction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 466. Neuroactive ligand-receptor interaction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
467	Neuroactive ligand-receptor interaction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand-receptor interaction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Neuroactive ligand-receptor interaction × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 467. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
468	Neuroactive ligand-receptor interaction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand-receptor interaction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 467. Neuroactive ligand-receptor interaction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
469	Neuroactive ligand-receptor interaction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand-receptor interaction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 469. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
470	Neuroactive ligand-receptor interaction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Neuroactive ligand-receptor interaction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Neuroactive ligand-receptor interaction × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 469. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
471	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬 Neuroactive ligand-receptor interaction × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine 💬 Neuroactive ligand-receptor interaction × Name Other Names Diphenhydramine Restamin	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 471. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
472	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬 Neuroactive ligand-receptor interaction × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Diphenhydramine hydrochloride Benadryl	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 471. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
473	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬 Neuroactive ligand-receptor interaction × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine salicylate 💬 Neuroactive ligand-receptor interaction × Name Other Names Diphenhydramine salicylate Diphenhydramine salicylate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 471. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
474	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬 Neuroactive ligand-receptor interaction × Name Full Name HRH1 histamine H1 receptor	Diphenhydramine citrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Diphenhydramine citrate Diphenhydramine citrate	Diphenhydramine	[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬 471. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease;
475	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 glucocorticoid receptor isoform alpha	Dexamethasone 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexamethasone Decadron Maxidex DEXTENZA HEMADY OZURDEX DEXAMETHASONE INTENSOL TAPERDEX 12-DAY TAPERDEX 6-DAY	Dexamethasone	[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬 475. Neuroactive ligand-receptor interaction × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 14 Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy; 16 Crow-Fukase syndrome;Polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes syndrome;POEMS syndrome;Takatsuki disease;Polyneuropathy, endocrinopathy, plasma cell dyscrasia syndrome;PEP syndrome; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 28 Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Transthyretin amyloid cardiomyopathy;ATTR-CM;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Transthyretin amyloid cardiomyopathy;ATTR-CM;Hereditary systemic amyloidosis; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;Hyperprolactinemia; 75 Cushing disease;Cushing syndrome; 81 Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Aldosterone synthase deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency; 84 Sarcoidosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 162 Pemphigoid;Bullous pemphigoid;BP;Epidermolysis bullosa acquisita;Acquired epidermolysis bullosa; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 257 Hepatic glycogenosis;Liver glycogenosis;Hepatic glycogen storage disease;Liver glycogen storage disease;Glycogen storage disease type I;GSDI;von Gierke disease;Glucose-6-phosphatase deficiency;G6Pase deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type VI;GSDVI;Hers disease;Hers syndrome;Hepatic phosphorylase deficiency;Liver phosphorylase deficiency;Glycogen storage disease type IX;GSDIX;Phosphorylase kinase deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Adult polyglucosan body disease; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 296 Biliary atresia; 299 Cystic fibrosis;CF; 331 Idiopathic multicentric castleman disease;iMCD;Castleman disease;
476	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 glucocorticoid receptor isoform alpha	Dexamethasone sodium phosphate 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexamethasone sodium phosphate Dalalone Maxidex	Dexamethasone	[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬 475. Neuroactive ligand-receptor interaction × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 14 Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy; 16 Crow-Fukase syndrome;Polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes syndrome;POEMS syndrome;Takatsuki disease;Polyneuropathy, endocrinopathy, plasma cell dyscrasia syndrome;PEP syndrome; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 28 Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Transthyretin amyloid cardiomyopathy;ATTR-CM;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Transthyretin amyloid cardiomyopathy;ATTR-CM;Hereditary systemic amyloidosis; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;Hyperprolactinemia; 75 Cushing disease;Cushing syndrome; 81 Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Aldosterone synthase deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency; 84 Sarcoidosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 162 Pemphigoid;Bullous pemphigoid;BP;Epidermolysis bullosa acquisita;Acquired epidermolysis bullosa; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 257 Hepatic glycogenosis;Liver glycogenosis;Hepatic glycogen storage disease;Liver glycogen storage disease;Glycogen storage disease type I;GSDI;von Gierke disease;Glucose-6-phosphatase deficiency;G6Pase deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type VI;GSDVI;Hers disease;Hers syndrome;Hepatic phosphorylase deficiency;Liver phosphorylase deficiency;Glycogen storage disease type IX;GSDIX;Phosphorylase kinase deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Adult polyglucosan body disease; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 296 Biliary atresia; 299 Cystic fibrosis;CF; 331 Idiopathic multicentric castleman disease;iMCD;Castleman disease;
477	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 glucocorticoid receptor isoform alpha	Dexamethasone phosphate 💬 Neuroactive ligand-receptor interaction × Name Other Names Dexamethasone phosphate Decadron-phosphate	Dexamethasone	[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬 475. Neuroactive ligand-receptor interaction × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 14 Chronic inflammatory demyelinating polyneuropathy;Chronic inflammatory demyelinating polyradiculoneuropathy;CIDP;Multifocal motor neuropathy; 16 Crow-Fukase syndrome;Polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes syndrome;POEMS syndrome;Takatsuki disease;Polyneuropathy, endocrinopathy, plasma cell dyscrasia syndrome;PEP syndrome; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 28 Systemic amyloidosis;Immunoglobulin light chain amyloidosis;Amyloid light-chain amyloidosis;AL amyloidosis;Immunoglobulin light chain amyloidosis;Immunoglobulin-related amyloidosis;Amyloid heavy-chain amyloidosis;Amyloid heavy-chain amyloidosis;AH amyloidosis;Systemic wild-type transthyretin amyloidosis;Senile systemic amyloidosis;SSA;Transthyretin amyloid cardiomyopathy;ATTR-CM;Hereditary transthyretin amyloidosis;Familial amyloidosis;Familial amyloid polyneuropathy;FAP;Transthyretin amyloid cardiomyopathy;ATTR-CM;Hereditary systemic amyloidosis; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 64 Thrombotic thrombocytopenic purpura;TTP;Upshaw-Schulman syndrome;USS; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 74 Prolactin secreting pituitary adenoma;Pituitary PRL secretion hyperthyroidism;Prolactinoma;Prolactin secreting adenoma;Hyperprolactinemia; 75 Cushing disease;Cushing syndrome; 81 Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Aldosterone synthase deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency; 84 Sarcoidosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 162 Pemphigoid;Bullous pemphigoid;BP;Epidermolysis bullosa acquisita;Acquired epidermolysis bullosa; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 257 Hepatic glycogenosis;Liver glycogenosis;Hepatic glycogen storage disease;Liver glycogen storage disease;Glycogen storage disease type I;GSDI;von Gierke disease;Glucose-6-phosphatase deficiency;G6Pase deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type VI;GSDVI;Hers disease;Hers syndrome;Hepatic phosphorylase deficiency;Liver phosphorylase deficiency;Glycogen storage disease type IX;GSDIX;Phosphorylase kinase deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Adult polyglucosan body disease; 283 Acquired pure red cell aplasia;Pure red cell aplasia; 296 Biliary atresia; 299 Cystic fibrosis;CF; 331 Idiopathic multicentric castleman disease;iMCD;Castleman disease;
478	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 glucocorticoid receptor isoform alpha	Triamcinolone 💬 Neuroactive ligand-receptor interaction × Name Other Names Triamcinolone Aristocort Kenacort	Triamcinolone	[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬 478. Neuroactive ligand-receptor interaction × Disease ID Name 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 56 Behcet disease;Behçet disease;BD;Behçet syndrome;Silk Road disease; 70 Spinal stenosis;Extensive spinal canal stenosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 162 Pemphigoid;Bullous pemphigoid;BP;Epidermolysis bullosa acquisita;Acquired epidermolysis bullosa; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
479	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 glucocorticoid receptor isoform alpha	Triamcinolone acetonide 💬 Neuroactive ligand-receptor interaction × Name Other Names Triamcinolone acetonide Azmacort Kenalog Nasacort KENALOG-10 KENALOG-40 TRIESENCE XIPERE ZILRETTA KOURZEQ ORALONE SCARZEN TRIDERM	Triamcinolone	[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬 478. Neuroactive ligand-receptor interaction × Disease ID Name 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 56 Behcet disease;Behçet disease;BD;Behçet syndrome;Silk Road disease; 70 Spinal stenosis;Extensive spinal canal stenosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 162 Pemphigoid;Bullous pemphigoid;BP;Epidermolysis bullosa acquisita;Acquired epidermolysis bullosa; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
480	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 glucocorticoid receptor isoform alpha	Triamcinolone diacetate 💬 Neuroactive ligand-receptor interaction × Name Other Names Triamcinolone diacetate Aristocort	Triamcinolone	[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬 478. Neuroactive ligand-receptor interaction × Disease ID Name 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 56 Behcet disease;Behçet disease;BD;Behçet syndrome;Silk Road disease; 70 Spinal stenosis;Extensive spinal canal stenosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 162 Pemphigoid;Bullous pemphigoid;BP;Epidermolysis bullosa acquisita;Acquired epidermolysis bullosa; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
481	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬 Neuroactive ligand-receptor interaction × Name Full Name NR3C1 glucocorticoid receptor isoform alpha	Triamcinolone hexacetonide 💬 Neuroactive ligand-receptor interaction × Name Other Names Triamcinolone hexacetonide Aristospan	Triamcinolone	[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬 478. Neuroactive ligand-receptor interaction × Disease ID Name 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 56 Behcet disease;Behçet disease;BD;Behçet syndrome;Silk Road disease; 70 Spinal stenosis;Extensive spinal canal stenosis; 90 Retinitis pigmentosa;Rod dystrophy;Cone-rod dystrophy;Rod-Cone Dystrophy; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 162 Pemphigoid;Bullous pemphigoid;BP;Epidermolysis bullosa acquisita;Acquired epidermolysis bullosa; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
482	Neuroactive ligand-receptor interaction 💬	[3] OPRD1, OPRK1, OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Oxycodone hydrochloride Oxecta Oxycontin Roxicodone OXAYDO ROXYBOND OXYCODONE HCL OXYCODONE HYDCHLORIDE OXYCODONE HYDROCHLORIDE ORAL SOLUTION	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 482. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
483	Neuroactive ligand-receptor interaction 💬	[3] OPRD1, OPRK1, OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone terephthalate 💬 Neuroactive ligand-receptor interaction × Name Other Names Oxycodone terephthalate Oxycodone terephthalate	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 482. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
484	Neuroactive ligand-receptor interaction 💬	[3] OPRD1, OPRK1, OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRD1 delta-type opioid receptor OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Oxycodone 💬 Neuroactive ligand-receptor interaction × Name Other Names Oxycodone XTAMPZA	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 482. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
485	Neuroactive ligand-receptor interaction 💬	[2] OPRK1, OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Buprenorphine hydrochloride Buprenex BELBUCA BUPRENORPHINE BUPRENORPHINE HCL BUPRENORPHINE SUBLINGUAL BUPRENORPHINE SUBLINGUAL C-III	Buprenorphine	[3] 46, 70, 298 💬 485. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
486	Neuroactive ligand-receptor interaction 💬	[2] OPRK1, OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRK1 kappa-type opioid receptor isoform 1 OPRM1 mu-type opioid receptor isoform MOR-1	Buprenorphine 💬 Neuroactive ligand-receptor interaction × Name Other Names Buprenorphine Temgesic BRIXADI BUTRANS SUBLOCADE BUPRENORPHINE TRANSDERMAL SYSTEM	Buprenorphine	[3] 46, 70, 298 💬 485. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
487	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl 💬 Neuroactive ligand-receptor interaction × Name Other Names Fentanyl Duragesic Subsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 487. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
488	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl citrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Fentanyl citrate Abstral Fentora Lazanda Oralet	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 487. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
489	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Fentanyl hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Fentanyl hydrochloride Ionsys	Fentanyl	[6] 46, 70, 97, 215, 231, 298 💬 487. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 215 Tetralogy of Fallot;Fallot tetralogy; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
490	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Hydromorphone hydrochloride Dilaudid Exalgo Palladone	Hydromorphone	[1] 70 💬 490. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
491	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Hydromorphone 💬 Neuroactive ligand-receptor interaction × Name Other Names Hydromorphone Hydromorphone	Hydromorphone	[1] 70 💬 490. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
492	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine sulfate 💬 Neuroactive ligand-receptor interaction × Name Other Names Morphine sulfate Morphine sulfate hydrate Morphine sulfate pentahydrate Astramor PH Avinza Depodur Kadian MS contin DURAMORPH MITIGO	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 492. Neuroactive ligand-receptor interaction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
493	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine hydrochloride hydrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Morphine hydrochloride hydrate Morphine hydrochloride trihydrate Anpec	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 492. Neuroactive ligand-receptor interaction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
494	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine 💬 Neuroactive ligand-receptor interaction × Name Other Names Morphine Substitol	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 492. Neuroactive ligand-receptor interaction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
495	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Morphine tartrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Morphine tartrate Morphine tartrate	Morphine	[6] 36, 46, 70, 85, 86, 298 💬 492. Neuroactive ligand-receptor interaction × Disease ID Name 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 85 Idiopathic interstitial pneumonia;IIPs;Idiopathic pulmonary fibrosis;IPF;Idiopathic non-specific interstitial pneumonia;Idiopathic NSIP;Respiratory bronchiolitis - associated interstitial lung disease;RB-ILD;Desquamative interstitial pneumonia;DIP;Cryptogenic organizing pneumonia;COP;Acute interstitial pneumonia;AIP;Idiopathic lymphocytic interstitial pneumonia;Idiopathic LIP;Idiopathic PPFE; 86 Pulmonary arterial hypertension;PAH; 298 Hereditary pancreatitis;Chronic pancreatitis;
496	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Oliceridine 💬 Neuroactive ligand-receptor interaction × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 496. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
497	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Remifentanil hydrochloride Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 497. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
498	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Remifentanil 💬 Neuroactive ligand-receptor interaction × Name Other Names Remifentanil Ultiva	Remifentanil	[4]  6 , 22, 70, 96 💬 497. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
499	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil citrate 💬 Neuroactive ligand-receptor interaction × Name Other Names Sufentanil citrate Dsuvia Sufenta	Sufentanil	[5] 11, 22, 46, 70, 280 💬 499. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
500	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Sufentanil 💬 Neuroactive ligand-receptor interaction × Name Other Names Sufentanil Sufentanil	Sufentanil	[5] 11, 22, 46, 70, 280 💬 499. Neuroactive ligand-receptor interaction × Disease ID Name 11 Myasthenia gravis;MG; 22 Moyamoya disease;Occlusive disease in circle of Willis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 280 Huge arteriovenous malformation with cervicofacial or limb lesion;Huge arteriovenous malformation;Arteriovenous malformation;Gigantic arteriovenous malformation;
501	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol hydrochloride 💬 Neuroactive ligand-receptor interaction × Name Other Names Tramadol hydrochloride Ultram CONZIP TRAMADOL HCL TRAMADOL HCL ER	Tramadol	[4] 46, 70, 226, 271 💬 501. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
502	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬 Neuroactive ligand-receptor interaction × Name Full Name OPRM1 mu-type opioid receptor isoform MOR-1	Tramadol 💬 Neuroactive ligand-receptor interaction × Name Other Names Tramadol Amanda	Tramadol	[4] 46, 70, 226, 271 💬 501. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
503	Neuroactive ligand-receptor interaction 💬	[1] OXTR 💬 Neuroactive ligand-receptor interaction × Name Full Name OXTR oxytocin receptor	Oxytocin 💬 Neuroactive ligand-receptor interaction × Name Other Names Oxytocin Pitocin Syntocinon	Oxytocin	[8]  6 , 70, 72, 127, 168, 193, 206, 226 💬 503. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 127 Frontotemporal lobar degeneration;Frontotemporal dementia, behavioral abnormal type;Frontotemporal dementia;Semantic dementia; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 193 Prader-Willi syndrome; 206 Fragile X syndrome; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
504	Neuroactive ligand-receptor interaction 💬	[1] PLG 💬 Neuroactive ligand-receptor interaction × Name Full Name PLG plasminogen isoform 1 precursor	Aminocaproic acid 💬 Neuroactive ligand-receptor interaction × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 504. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
505	Neuroactive ligand-receptor interaction 💬	[1] PLG 💬 Neuroactive ligand-receptor interaction × Name Full Name PLG plasminogen isoform 1 precursor	Tranexamic acid 💬 Neuroactive ligand-receptor interaction × Name Other Names Tranexamic acid Cyklokapron Rikavarin Transamin TRANEXAMIC ACID IN SODIUM CHLORIDE	Tranexamic acid	[7] 46, 65, 70, 215, 227, 274, 299 💬 505. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 215 Tetralogy of Fallot;Fallot tetralogy; 227 Osler disease;Hereditary hemorrhagic telangiectasia;HHT;Osler-Weber-Rendu disease; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
506	Neuroactive ligand-receptor interaction 💬	[3] PRSS1, PRSS2, PRSS3 💬 Neuroactive ligand-receptor interaction × Name Full Name PRSS1 serine protease 1 preproprotein PRSS2 trypsin-2 isoform 2 preproprotein PRSS3 trypsin-3 isoform 3 preproprotein	Ulinastatin 💬 Neuroactive ligand-receptor interaction × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 506. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
507	Neuroactive ligand-receptor interaction 💬	[1] PTGER1 💬 Neuroactive ligand-receptor interaction × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Alprostadil 💬 Neuroactive ligand-receptor interaction × Name Other Names Alprostadil Prostin VR pediatric Caverject Edex Muse CAVERJECT IMPULSE PROSTIN	Alprostadil	[2] 51, 70 💬 507. Neuroactive ligand-receptor interaction × Disease ID Name 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis;
508	Neuroactive ligand-receptor interaction 💬	[1] PTGER1 💬 Neuroactive ligand-receptor interaction × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost 💬 Neuroactive ligand-receptor interaction × Name Other Names Limaprost Limaprost	Limaprost	[1] 70 💬 508. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
509	Neuroactive ligand-receptor interaction 💬	[1] PTGER1 💬 Neuroactive ligand-receptor interaction × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost alfadex 💬 Neuroactive ligand-receptor interaction × Name Other Names Limaprost alfadex Opalmon	Limaprost	[1] 70 💬 508. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
510	Neuroactive ligand-receptor interaction 💬	[3] PTGER2, PTGER3, PTGER4 💬 Neuroactive ligand-receptor interaction × Name Full Name PTGER2 prostaglandin E2 receptor EP2 subtype PTGER3 prostaglandin E2 receptor EP3 subtype isoform 4 PTGER4 prostaglandin E2 receptor EP4 subtype	Misoprostol 💬 Neuroactive ligand-receptor interaction × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 510. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
511	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬 Neuroactive ligand-receptor interaction × Name Full Name PTGIR prostacyclin receptor	Selexipag 💬 Neuroactive ligand-receptor interaction × Name Other Names Selexipag Uptravi	Selexipag	[6] 47, 51, 70, 84, 86, 88 💬 511. Neuroactive ligand-receptor interaction × Disease ID Name 47 Buerger disease;Thromboangiitis obliterans; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 84 Sarcoidosis; 86 Pulmonary arterial hypertension;PAH; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;
512	Neuroactive ligand-receptor interaction 💬	[1] PTH1R 💬 Neuroactive ligand-receptor interaction × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Neuroactive ligand-receptor interaction × Name Other Names Teriparatide acetate Human PHT	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 512. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
513	Neuroactive ligand-receptor interaction 💬	[1] PTH1R 💬 Neuroactive ligand-receptor interaction × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide 💬 Neuroactive ligand-receptor interaction × Name Other Names Teriparatide Forteo BONSITY	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 512. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
514	Neuroactive ligand-receptor interaction 💬	[1] PTH1R 💬 Neuroactive ligand-receptor interaction × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Neuroactive ligand-receptor interaction × Name Other Names Teriparatide acetate Teriparatide acetate hydrate Parathar	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 512. Neuroactive ligand-receptor interaction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
515	Neuroactive ligand-receptor interaction 💬	[2] PTH1R, PTH2R 💬 Neuroactive ligand-receptor interaction × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor PTH2R parathyroid hormone 2 receptor isoform 1 precursor	Parathyroid hormone 💬 Neuroactive ligand-receptor interaction × Name Other Names Parathyroid hormone ALX 1-11 Parathormone PTH Natpara	Parathyroid hormone	[2] 70, 235 💬 515. Neuroactive ligand-receptor interaction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease;
516	Neuroactive ligand-receptor interaction 💬	[1] TBXA2R 💬 Neuroactive ligand-receptor interaction × Name Full Name TBXA2R thromboxane A2 receptor isoform alpha	Cilostazol 💬 Neuroactive ligand-receptor interaction × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 516. Neuroactive ligand-receptor interaction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
517	Neutrophil extracellular trap formation 💬	[1] ELANE 💬 Neutrophil extracellular trap formation × Name Full Name ELANE neutrophil elastase preproprotein	Ulinastatin 💬 Neutrophil extracellular trap formation × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 517. Neutrophil extracellular trap formation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
518	NF-kappa B signaling pathway 💬	[1] PTGS2 💬 NF-kappa B signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 NF-kappa B signaling pathway × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 518. NF-kappa B signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
519	NF-kappa B signaling pathway 💬	[1] PTGS2 💬 NF-kappa B signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 NF-kappa B signaling pathway × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 519. NF-kappa B signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
520	NF-kappa B signaling pathway 💬	[1] PTGS2 💬 NF-kappa B signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 NF-kappa B signaling pathway × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 520. NF-kappa B signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
521	NF-kappa B signaling pathway 💬	[1] PTGS2 💬 NF-kappa B signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 NF-kappa B signaling pathway × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 521. NF-kappa B signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
522	NF-kappa B signaling pathway 💬	[1] PTGS2 💬 NF-kappa B signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 NF-kappa B signaling pathway × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 521. NF-kappa B signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
523	NF-kappa B signaling pathway 💬	[1] TNFSF11 💬 NF-kappa B signaling pathway × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 NF-kappa B signaling pathway × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 523. NF-kappa B signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
524	Nicotine addiction 💬	[4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 Nicotine addiction × Name Full Name CHRNA4 neuronal acetylcholine receptor subunit alpha-4 isoform 1 precursor CHRNA6 neuronal acetylcholine receptor subunit alpha-6 isoform 1 precursor CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor CHRNB2 neuronal acetylcholine receptor subunit beta-2 precursor	Rocuronium bromide 💬 Nicotine addiction × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 524. Nicotine addiction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
525	Nicotine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam 💬 Nicotine addiction × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 525. Nicotine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
526	Nicotine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam hydrochloride 💬 Nicotine addiction × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 525. Nicotine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
527	Nicotine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam maleate 💬 Nicotine addiction × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 525. Nicotine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
528	Nicotine addiction 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nicotine addiction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Nicotine addiction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 528. Nicotine addiction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
529	Nicotine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Nicotine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Nicotine addiction × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 529. Nicotine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
530	Nicotine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Nicotine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Nicotine addiction × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 529. Nicotine addiction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
531	Nicotine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Nicotine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Nicotine addiction × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 531. Nicotine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
532	Nicotine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Nicotine addiction × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Nicotine addiction × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 531. Nicotine addiction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
533	Olfactory transduction 💬	[2] ARRB1, ARRB2 💬 Olfactory transduction × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Olfactory transduction × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 533. Olfactory transduction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
534	Osteoclast differentiation 💬	[1] CALCR 💬 Osteoclast differentiation × Name Full Name CALCR calcitonin receptor isoform 2 precursor	Elcatonin 💬 Osteoclast differentiation × Name Other Names Elcatonin Adevirock	Elcatonin	[1] 70 💬 534. Osteoclast differentiation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
535	Osteoclast differentiation 💬	[1] TNFSF11 💬 Osteoclast differentiation × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 Osteoclast differentiation × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 535. Osteoclast differentiation × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
536	Ovarian steroidogenesis 💬	[1] PTGS2 💬 Ovarian steroidogenesis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Ovarian steroidogenesis × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 536. Ovarian steroidogenesis × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
537	Ovarian steroidogenesis 💬	[1] PTGS2 💬 Ovarian steroidogenesis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Ovarian steroidogenesis × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 537. Ovarian steroidogenesis × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
538	Ovarian steroidogenesis 💬	[1] PTGS2 💬 Ovarian steroidogenesis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Ovarian steroidogenesis × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 538. Ovarian steroidogenesis × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
539	Ovarian steroidogenesis 💬	[1] PTGS2 💬 Ovarian steroidogenesis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Ovarian steroidogenesis × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 539. Ovarian steroidogenesis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
540	Ovarian steroidogenesis 💬	[1] PTGS2 💬 Ovarian steroidogenesis × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Ovarian steroidogenesis × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 539. Ovarian steroidogenesis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
541	Oxytocin signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Oxytocin signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Oxytocin signaling pathway × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 541. Oxytocin signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
542	Oxytocin signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Oxytocin signaling pathway × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Oxytocin signaling pathway × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 541. Oxytocin signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
543	Oxytocin signaling pathway 💬	[2] CACNA2D1, CACNA2D2 💬 Oxytocin signaling pathway × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor	Mirogabalin 💬 Oxytocin signaling pathway × Name Other Names Mirogabalin Mirogabalin	Mirogabalin	[1] 70 💬 543. Oxytocin signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
544	Oxytocin signaling pathway 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Oxytocin signaling pathway × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Gabapentin 💬 Oxytocin signaling pathway × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 544. Oxytocin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
545	Oxytocin signaling pathway 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Oxytocin signaling pathway × Name Full Name CACNA2D1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 preproprotein CACNA2D2 voltage-dependent calcium channel subunit alpha-2/delta-2 isoform c precursor CACNA2D3 voltage-dependent calcium channel subunit alpha-2/delta-3 precursor CACNA2D4 voltage-dependent calcium channel subunit alpha-2/delta-4	Pregabalin 💬 Oxytocin signaling pathway × Name Other Names Pregabalin Lyrica LYRICA CR PREGABALIN CAPSULES, CV PREGABALIN EXTENDED RELEASE PREGABLIN	Pregabalin	[5] 13, 36, 46, 70, 298 💬 545. Oxytocin signaling pathway × Disease ID Name 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 298 Hereditary pancreatitis;Chronic pancreatitis;
546	Oxytocin signaling pathway 💬	[1] OXTR 💬 Oxytocin signaling pathway × Name Full Name OXTR oxytocin receptor	Oxytocin 💬 Oxytocin signaling pathway × Name Other Names Oxytocin Pitocin Syntocinon	Oxytocin	[8]  6 , 70, 72, 127, 168, 193, 206, 226 💬 546. Oxytocin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 72 Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;Disorders of antidiuretic hormone (ADH) secretion;Central diabetes insipidus;Syndrome of inappropriate secretion of ADH;SIADH; 127 Frontotemporal lobar degeneration;Frontotemporal dementia, behavioral abnormal type;Frontotemporal dementia;Semantic dementia; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 193 Prader-Willi syndrome; 206 Fragile X syndrome; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
547	Oxytocin signaling pathway 💬	[1] PTGS2 💬 Oxytocin signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Oxytocin signaling pathway × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 547. Oxytocin signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
548	Oxytocin signaling pathway 💬	[1] PTGS2 💬 Oxytocin signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Oxytocin signaling pathway × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 548. Oxytocin signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
549	Oxytocin signaling pathway 💬	[1] PTGS2 💬 Oxytocin signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Oxytocin signaling pathway × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 549. Oxytocin signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
550	Oxytocin signaling pathway 💬	[1] PTGS2 💬 Oxytocin signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Oxytocin signaling pathway × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 550. Oxytocin signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
551	Oxytocin signaling pathway 💬	[1] PTGS2 💬 Oxytocin signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Oxytocin signaling pathway × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 550. Oxytocin signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
552	Pancreatic secretion 💬	[1] CHRM3 💬 Pancreatic secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Rocuronium bromide 💬 Pancreatic secretion × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 552. Pancreatic secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
553	Pancreatic secretion 💬	[5] CTRB1, CTRB2, PRSS1, PRSS2, PRSS3 💬 Pancreatic secretion × Name Full Name CTRB1 chymotrypsinogen B isoform 1 precursor CTRB2 chymotrypsinogen B2 precursor PRSS1 serine protease 1 preproprotein PRSS2 trypsin-2 isoform 2 preproprotein PRSS3 trypsin-3 isoform 3 preproprotein	Ulinastatin 💬 Pancreatic secretion × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 553. Pancreatic secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
554	Parathyroid hormone synthesis, secretion and action 💬	[2] ARRB1, ARRB2 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 554. Parathyroid hormone synthesis, secretion and action × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
555	Parathyroid hormone synthesis, secretion and action 💬	[1] PTH1R 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Parathyroid hormone 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Parathyroid hormone ALX 1-11 Parathormone PTH Natpara	Parathyroid hormone	[2] 70, 235 💬 555. Parathyroid hormone synthesis, secretion and action × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease;
556	Parathyroid hormone synthesis, secretion and action 💬	[1] PTH1R 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Teriparatide acetate Human PHT	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 556. Parathyroid hormone synthesis, secretion and action × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
557	Parathyroid hormone synthesis, secretion and action 💬	[1] PTH1R 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Teriparatide Forteo BONSITY	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 556. Parathyroid hormone synthesis, secretion and action × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
558	Parathyroid hormone synthesis, secretion and action 💬	[1] PTH1R 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name PTH1R parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Teriparatide acetate 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Teriparatide acetate Teriparatide acetate hydrate Parathar	Teriparatide	[7] 46, 68, 70, 71, 172, 235, 274 💬 556. Parathyroid hormone synthesis, secretion and action × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 68 Ossification of the ligamentum flavum;Ossification of ligamentum flavum;Ossified ligamentum flavum;OLF; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 172 Hypophosphatasia; 235 Hypoparathyroidism;Accessory thyroid hypergasia disease; 274 Osteogenesis Imperfecta;
559	Parathyroid hormone synthesis, secretion and action 💬	[1] TNFSF11 💬 Parathyroid hormone synthesis, secretion and action × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 Parathyroid hormone synthesis, secretion and action × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 559. Parathyroid hormone synthesis, secretion and action × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
560	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 Pathways in cancer × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 560. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
561	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 Pathways in cancer × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 560. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
562	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 Pathways in cancer × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 560. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
563	Pathways in cancer 💬	[1] EPOR 💬 Pathways in cancer × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 Pathways in cancer × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 560. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
564	Pathways in cancer 💬	[1] PTGER1 💬 Pathways in cancer × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Alprostadil 💬 Pathways in cancer × Name Other Names Alprostadil Prostin VR pediatric Caverject Edex Muse CAVERJECT IMPULSE PROSTIN	Alprostadil	[2] 51, 70 💬 564. Pathways in cancer × Disease ID Name 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis;
565	Pathways in cancer 💬	[1] PTGER1 💬 Pathways in cancer × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost 💬 Pathways in cancer × Name Other Names Limaprost Limaprost	Limaprost	[1] 70 💬 565. Pathways in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
566	Pathways in cancer 💬	[1] PTGER1 💬 Pathways in cancer × Name Full Name PTGER1 prostaglandin E2 receptor EP1 subtype	Limaprost alfadex 💬 Pathways in cancer × Name Other Names Limaprost alfadex Opalmon	Limaprost	[1] 70 💬 565. Pathways in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
567	Pathways in cancer 💬	[3] PTGER2, PTGER3, PTGER4 💬 Pathways in cancer × Name Full Name PTGER2 prostaglandin E2 receptor EP2 subtype PTGER3 prostaglandin E2 receptor EP3 subtype isoform 4 PTGER4 prostaglandin E2 receptor EP4 subtype	Misoprostol 💬 Pathways in cancer × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 567. Pathways in cancer × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
568	Pathways in cancer 💬	[1] PTGS2 💬 Pathways in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Pathways in cancer × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 568. Pathways in cancer × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
569	Pathways in cancer 💬	[1] PTGS2 💬 Pathways in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Pathways in cancer × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 569. Pathways in cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
570	Pathways in cancer 💬	[1] PTGS2 💬 Pathways in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Pathways in cancer × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 570. Pathways in cancer × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
571	Pathways in cancer 💬	[1] PTGS2 💬 Pathways in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Pathways in cancer × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 571. Pathways in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
572	Pathways in cancer 💬	[1] PTGS2 💬 Pathways in cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Pathways in cancer × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 571. Pathways in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
573	Pathways of neurodegeneration - multiple diseases 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 573. Pathways of neurodegeneration - multiple diseases × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
574	Pathways of neurodegeneration - multiple diseases 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 573. Pathways of neurodegeneration - multiple diseases × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
575	Pathways of neurodegeneration - multiple diseases 💬	[4] CHRM1, CHRM3, CHRM5, CHRNA7 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM3 muscarinic acetylcholine receptor M3 CHRM5 muscarinic acetylcholine receptor M5 CHRNA7 neuronal acetylcholine receptor subunit alpha-7 isoform 1 precursor	Rocuronium bromide 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 575. Pathways of neurodegeneration - multiple diseases × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
576	Pathways of neurodegeneration - multiple diseases 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 576. Pathways of neurodegeneration - multiple diseases × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
577	Pathways of neurodegeneration - multiple diseases 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 576. Pathways of neurodegeneration - multiple diseases × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
578	Pathways of neurodegeneration - multiple diseases 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 578. Pathways of neurodegeneration - multiple diseases × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
579	Pathways of neurodegeneration - multiple diseases 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 578. Pathways of neurodegeneration - multiple diseases × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
580	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 580. Pathways of neurodegeneration - multiple diseases × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
581	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 581. Pathways of neurodegeneration - multiple diseases × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
582	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 582. Pathways of neurodegeneration - multiple diseases × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
583	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 583. Pathways of neurodegeneration - multiple diseases × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
584	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬 Pathways of neurodegeneration - multiple diseases × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Pathways of neurodegeneration - multiple diseases × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 583. Pathways of neurodegeneration - multiple diseases × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
585	Phagocytosis 💬	[1] ELANE 💬 Phagocytosis × Name Full Name ELANE neutrophil elastase preproprotein	Ulinastatin 💬 Phagocytosis × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 585. Phagocytosis × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
586	PI3K-Akt signaling pathway 💬	[2] CHRM1, CHRM2 💬 PI3K-Akt signaling pathway × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2	Rocuronium bromide 💬 PI3K-Akt signaling pathway × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 586. PI3K-Akt signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
587	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin alfa 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin alfa Epoetin kappa Epoetin alfa-epbx Epogen Epoetin alfa BS PROCRIT RETACRIT	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 587. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
588	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin epsilon 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin epsilon Epoetin epsilon	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 587. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
589	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin theta 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin theta Biopoin Eporatio	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 587. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
590	PI3K-Akt signaling pathway 💬	[1] EPOR 💬 PI3K-Akt signaling pathway × Name Full Name EPOR erythropoietin receptor precursor	Epoetin zeta 💬 PI3K-Akt signaling pathway × Name Other Names Epoetin zeta Retacrit Silapo	Erythropoietin	[11]  2 ,  6 , 13, 18, 22, 47, 61, 63, 70, 95, 96 💬 587. PI3K-Akt signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 22 Moyamoya disease;Occlusive disease in circle of Willis; 47 Buerger disease;Thromboangiitis obliterans; 61 Autoimmune hemolytic anemia;AIHA;Cold agglutinin disease;CAD;Paroxysmal cold hemoglobinuria;Evans syndrome; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD;
591	Platelet activation 💬	[1] PTGIR 💬 Platelet activation × Name Full Name PTGIR prostacyclin receptor	Selexipag 💬 Platelet activation × Name Other Names Selexipag Uptravi	Selexipag	[6] 47, 51, 70, 84, 86, 88 💬 591. Platelet activation × Disease ID Name 47 Buerger disease;Thromboangiitis obliterans; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 84 Sarcoidosis; 86 Pulmonary arterial hypertension;PAH; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;
592	Platelet activation 💬	[1] PTGS1 💬 Platelet activation × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor	Acetaminophen 💬 Platelet activation × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 592. Platelet activation × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
593	Platelet activation 💬	[1] PTGS1 💬 Platelet activation × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor	Ketorolac tromethamine 💬 Platelet activation × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 593. Platelet activation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
594	Platelet activation 💬	[1] PTGS1 💬 Platelet activation × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor	Ketorolac 💬 Platelet activation × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 593. Platelet activation × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
595	Platelet activation 💬	[1] TBXA2R 💬 Platelet activation × Name Full Name TBXA2R thromboxane A2 receptor isoform alpha	Cilostazol 💬 Platelet activation × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 595. Platelet activation × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
596	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Prion disease × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Prion disease × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 596. Prion disease × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
597	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Prion disease × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Prion disease × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 596. Prion disease × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
598	Prion disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Prion disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Prion disease × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 598. Prion disease × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
599	Prion disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Prion disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Prion disease × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 598. Prion disease × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
600	Prion disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Prion disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Prion disease × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 600. Prion disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
601	Prion disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Prion disease × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Prion disease × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 600. Prion disease × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
602	Progesterone-mediated oocyte maturation 💬	[1] PDE3B 💬 Progesterone-mediated oocyte maturation × Name Full Name PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Progesterone-mediated oocyte maturation × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 602. Progesterone-mediated oocyte maturation × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
603	Prolactin signaling pathway 💬	[1] TNFSF11 💬 Prolactin signaling pathway × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 Prolactin signaling pathway × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 603. Prolactin signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
604	Prostate cancer 💬	[1] PLAT 💬 Prostate cancer × Name Full Name PLAT tissue-type plasminogen activator isoform 1 preproprotein	Aminocaproic acid 💬 Prostate cancer × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 604. Prostate cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
605	Protein digestion and absorption 💬	[5] CTRB1, CTRB2, PRSS1, PRSS2, PRSS3 💬 Protein digestion and absorption × Name Full Name CTRB1 chymotrypsinogen B isoform 1 precursor CTRB2 chymotrypsinogen B2 precursor PRSS1 serine protease 1 preproprotein PRSS2 trypsin-2 isoform 2 preproprotein PRSS3 trypsin-3 isoform 3 preproprotein	Ulinastatin 💬 Protein digestion and absorption × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 605. Protein digestion and absorption × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
606	Purine metabolism 💬	[2] PDE3A, PDE3B 💬 Purine metabolism × Name Full Name PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform 1 PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Purine metabolism × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 606. Purine metabolism × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
607	Rap1 signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Rap1 signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine 💬 Rap1 signaling pathway × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 607. Rap1 signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
608	Rap1 signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Rap1 signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine hydrochloride 💬 Rap1 signaling pathway × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 607. Rap1 signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
609	Rap1 signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Rap1 signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine hydrochloride 💬 Rap1 signaling pathway × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 609. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
610	Rap1 signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Rap1 signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine 💬 Rap1 signaling pathway × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 609. Rap1 signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
611	Ras signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Ras signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine 💬 Ras signaling pathway × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 611. Ras signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
612	Ras signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Ras signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine hydrochloride 💬 Ras signaling pathway × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 611. Ras signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
613	Ras signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Ras signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine hydrochloride 💬 Ras signaling pathway × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 613. Ras signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
614	Ras signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬 Ras signaling pathway × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine 💬 Ras signaling pathway × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 613. Ras signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
615	Regulation of actin cytoskeleton 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Regulation of actin cytoskeleton × Name Full Name CHRM1 muscarinic acetylcholine receptor M1 CHRM2 muscarinic acetylcholine receptor M2 CHRM3 muscarinic acetylcholine receptor M3 CHRM4 muscarinic acetylcholine receptor M4 CHRM5 muscarinic acetylcholine receptor M5	Rocuronium bromide 💬 Regulation of actin cytoskeleton × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 615. Regulation of actin cytoskeleton × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
616	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Regulation of lipolysis in adipocytes × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 616. Regulation of lipolysis in adipocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
617	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Regulation of lipolysis in adipocytes × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 616. Regulation of lipolysis in adipocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
618	Regulation of lipolysis in adipocytes 💬	[3] ADRB1, ADRB2, ADRB3 💬 Regulation of lipolysis in adipocytes × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Regulation of lipolysis in adipocytes × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 616. Regulation of lipolysis in adipocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
619	Regulation of lipolysis in adipocytes 💬	[1] PDE3B 💬 Regulation of lipolysis in adipocytes × Name Full Name PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Regulation of lipolysis in adipocytes × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 619. Regulation of lipolysis in adipocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
620	Regulation of lipolysis in adipocytes 💬	[1] PTGER3 💬 Regulation of lipolysis in adipocytes × Name Full Name PTGER3 prostaglandin E2 receptor EP3 subtype isoform 4	Misoprostol 💬 Regulation of lipolysis in adipocytes × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 620. Regulation of lipolysis in adipocytes × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
621	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬 Regulation of lipolysis in adipocytes × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Regulation of lipolysis in adipocytes × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 621. Regulation of lipolysis in adipocytes × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
622	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬 Regulation of lipolysis in adipocytes × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Regulation of lipolysis in adipocytes × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 622. Regulation of lipolysis in adipocytes × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
623	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬 Regulation of lipolysis in adipocytes × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Regulation of lipolysis in adipocytes × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 622. Regulation of lipolysis in adipocytes × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
624	Regulation of lipolysis in adipocytes 💬	[1] PTGS2 💬 Regulation of lipolysis in adipocytes × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Regulation of lipolysis in adipocytes × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 624. Regulation of lipolysis in adipocytes × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
625	Regulation of lipolysis in adipocytes 💬	[1] PTGS2 💬 Regulation of lipolysis in adipocytes × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Regulation of lipolysis in adipocytes × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 625. Regulation of lipolysis in adipocytes × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
626	Relaxin signaling pathway 💬	[2] ARRB1, ARRB2 💬 Relaxin signaling pathway × Name Full Name ARRB1 beta-arrestin-1 isoform A ARRB2 beta-arrestin-2 isoform 1	Oliceridine 💬 Relaxin signaling pathway × Name Other Names Oliceridine Olinvyk	Oliceridine	[2] 46, 70 💬 626. Relaxin signaling pathway × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis;
627	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Renin secretion × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 627. Renin secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
628	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Renin secretion × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 627. Renin secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
629	Renin secretion 💬	[3] ADRB1, ADRB2, ADRB3 💬 Renin secretion × Name Full Name ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Renin secretion × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 627. Renin secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
630	Renin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Renin secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Renin secretion × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 630. Renin secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
631	Renin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Renin secretion × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Renin secretion × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 630. Renin secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
632	Renin secretion 💬	[2] PDE3A, PDE3B 💬 Renin secretion × Name Full Name PDE3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform 1 PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform 2	Cilostazol 💬 Renin secretion × Name Other Names Cilostazol Pletal	Cilostazol	[7]  6 , 13, 46, 48, 51, 70, 124 💬 632. Renin secretion × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 48 Primary antiphospholipid syndrome;Primary antiphospholipid antibody syndrome;Primary APS;PAPS;Antiphospholipid syndrome; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 124 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy;CADASIL;Autosomal dominant cerebral artery disease with subcortical infarct and leukoencephalopathy;Autosomal dominant cerebral artery disease;
633	Renin secretion 💬	[2] PTGER2, PTGER4 💬 Renin secretion × Name Full Name PTGER2 prostaglandin E2 receptor EP2 subtype PTGER4 prostaglandin E2 receptor EP4 subtype	Misoprostol 💬 Renin secretion × Name Other Names Misoprostol Cytotec	Misoprostol	[3] 46, 70, 271 💬 633. Renin secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
634	Retrograde endocannabinoid signaling 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Retrograde endocannabinoid signaling × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Retrograde endocannabinoid signaling × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 634. Retrograde endocannabinoid signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
635	Retrograde endocannabinoid signaling 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Retrograde endocannabinoid signaling × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Retrograde endocannabinoid signaling × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 634. Retrograde endocannabinoid signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
636	Retrograde endocannabinoid signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam 💬 Retrograde endocannabinoid signaling × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 636. Retrograde endocannabinoid signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
637	Retrograde endocannabinoid signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam hydrochloride 💬 Retrograde endocannabinoid signaling × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 636. Retrograde endocannabinoid signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
638	Retrograde endocannabinoid signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Midazolam maleate 💬 Retrograde endocannabinoid signaling × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 636. Retrograde endocannabinoid signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
639	Retrograde endocannabinoid signaling 💬	[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Retrograde endocannabinoid signaling × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor GABRD gamma-aminobutyric acid receptor subunit delta precursor GABRE gamma-aminobutyric acid receptor subunit epsilon precursor GABRG1 gamma-aminobutyric acid receptor subunit gamma-1 precursor GABRG2 gamma-aminobutyric acid receptor subunit gamma-2 isoform 1 precursor GABRG3 gamma-aminobutyric acid receptor subunit gamma-3 isoform 1 precursor GABRP gamma-aminobutyric acid receptor subunit pi isoform 1 precursor GABRQ gamma-aminobutyric acid receptor subunit theta precursor	Propofol 💬 Retrograde endocannabinoid signaling × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 639. Retrograde endocannabinoid signaling × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
640	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬 Retrograde endocannabinoid signaling × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Retrograde endocannabinoid signaling × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 640. Retrograde endocannabinoid signaling × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
641	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬 Retrograde endocannabinoid signaling × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Retrograde endocannabinoid signaling × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 641. Retrograde endocannabinoid signaling × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
642	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬 Retrograde endocannabinoid signaling × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Retrograde endocannabinoid signaling × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 642. Retrograde endocannabinoid signaling × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
643	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬 Retrograde endocannabinoid signaling × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Retrograde endocannabinoid signaling × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 643. Retrograde endocannabinoid signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
644	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬 Retrograde endocannabinoid signaling × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Retrograde endocannabinoid signaling × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 643. Retrograde endocannabinoid signaling × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
645	Rheumatoid arthritis 💬	[1] TNFSF11 💬 Rheumatoid arthritis × Name Full Name TNFSF11 tumor necrosis factor ligand superfamily member 11 isoform 1	Denosumab 💬 Rheumatoid arthritis × Name Other Names Denosumab Denosumab-dssb Denosumab-bmwo Denosumab-qbde Denosumab-kyqq Denosumab-mobz Denosumab-desu Ospomyv Prolia Ranmark Xbryk Xgeva AUKELSO BILDYOS BILPREVDA BOMYNTRA BONCRESA BOSAYA CONEXXENCE ENOBY JUBBONTI JUBEREQ OSENVELT OSVYRTI OZILTUS STOBOCLO WYOST XTRENBO	Denosumab	[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬 645. Rheumatoid arthritis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 50 Dermatomyositis;Polymyositis;Idiopathic inflammatory myositis;IIM; 70 Spinal stenosis;Extensive spinal canal stenosis; 75 Cushing disease;Cushing syndrome; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 93 Primary biliary cholangitis;Primary biliary cirrhosis;PBC; 95 Autoimmune hepatitis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 223 Primary membranoproliferative glomerulonephritis;Primary MPGN;Primary membranoproliferative glomerulonephritis type I;Primary MPGN I;Primary membranoproliferative glomerulonephritis type III;Primary MPGN III;Membranoproliferative glomerulonephritis;Glomerulonephritis;C3 glomerulonephritis;C3 glomerulopathy;IC-MPGN;MPGN; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
646	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Salivary secretion × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 646. Salivary secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
647	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Salivary secretion × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 646. Salivary secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
648	Salivary secretion 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 Salivary secretion × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor ADRB1 beta-1 adrenergic receptor ADRB2 beta-2 adrenergic receptor ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Salivary secretion × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 646. Salivary secretion × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
649	Salivary secretion 💬	[1] CHRM3 💬 Salivary secretion × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Rocuronium bromide 💬 Salivary secretion × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 649. Salivary secretion × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
650	Serotonergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Serotonergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Serotonergic synapse × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 650. Serotonergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
651	Serotonergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Serotonergic synapse × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Serotonergic synapse × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 650. Serotonergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
652	Serotonergic synapse 💬	[3] GABRB1, GABRB2, GABRB3 💬 Serotonergic synapse × Name Full Name GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor	Midazolam 💬 Serotonergic synapse × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 652. Serotonergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
653	Serotonergic synapse 💬	[3] GABRB1, GABRB2, GABRB3 💬 Serotonergic synapse × Name Full Name GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor	Midazolam hydrochloride 💬 Serotonergic synapse × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 652. Serotonergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
654	Serotonergic synapse 💬	[3] GABRB1, GABRB2, GABRB3 💬 Serotonergic synapse × Name Full Name GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor	Midazolam maleate 💬 Serotonergic synapse × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 652. Serotonergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
655	Serotonergic synapse 💬	[3] GABRB1, GABRB2, GABRB3 💬 Serotonergic synapse × Name Full Name GABRB1 gamma-aminobutyric acid receptor subunit beta-1 precursor GABRB2 gamma-aminobutyric acid receptor subunit beta-2 isoform 1 precursor GABRB3 gamma-aminobutyric acid receptor subunit beta-3 isoform 1 precursor	Propofol 💬 Serotonergic synapse × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 655. Serotonergic synapse × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
656	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬 Serotonergic synapse × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Serotonergic synapse × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 656. Serotonergic synapse × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
657	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬 Serotonergic synapse × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Serotonergic synapse × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 657. Serotonergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
658	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬 Serotonergic synapse × Name Full Name PTGS1 prostaglandin G/H synthase 1 isoform 1 precursor PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Serotonergic synapse × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 657. Serotonergic synapse × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
659	Serotonergic synapse 💬	[1] PTGS2 💬 Serotonergic synapse × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Serotonergic synapse × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 659. Serotonergic synapse × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
660	Serotonergic synapse 💬	[1] PTGS2 💬 Serotonergic synapse × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Serotonergic synapse × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 660. Serotonergic synapse × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
661	Small cell lung cancer 💬	[1] PTGS2 💬 Small cell lung cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 Small cell lung cancer × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 661. Small cell lung cancer × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
662	Small cell lung cancer 💬	[1] PTGS2 💬 Small cell lung cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 Small cell lung cancer × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 662. Small cell lung cancer × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
663	Small cell lung cancer 💬	[1] PTGS2 💬 Small cell lung cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 Small cell lung cancer × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 663. Small cell lung cancer × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
664	Small cell lung cancer 💬	[1] PTGS2 💬 Small cell lung cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 Small cell lung cancer × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 664. Small cell lung cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
665	Small cell lung cancer 💬	[1] PTGS2 💬 Small cell lung cancer × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 Small cell lung cancer × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 664. Small cell lung cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
666	Sphingolipid signaling pathway 💬	[1] OPRD1 💬 Sphingolipid signaling pathway × Name Full Name OPRD1 delta-type opioid receptor	Oxycodone hydrochloride 💬 Sphingolipid signaling pathway × Name Other Names Oxycodone hydrochloride Oxecta Oxycontin Roxicodone OXAYDO ROXYBOND OXYCODONE HCL OXYCODONE HYDCHLORIDE OXYCODONE HYDROCHLORIDE ORAL SOLUTION	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 666. Sphingolipid signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
667	Sphingolipid signaling pathway 💬	[1] OPRD1 💬 Sphingolipid signaling pathway × Name Full Name OPRD1 delta-type opioid receptor	Oxycodone terephthalate 💬 Sphingolipid signaling pathway × Name Other Names Oxycodone terephthalate Oxycodone terephthalate	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 666. Sphingolipid signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
668	Sphingolipid signaling pathway 💬	[1] OPRD1 💬 Sphingolipid signaling pathway × Name Full Name OPRD1 delta-type opioid receptor	Oxycodone 💬 Sphingolipid signaling pathway × Name Other Names Oxycodone XTAMPZA	Oxycodone	[7]  6 , 13, 46, 70, 226, 231, 298 💬 666. Sphingolipid signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 298 Hereditary pancreatitis;Chronic pancreatitis;
669	Spinocerebellar ataxia 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Spinocerebellar ataxia × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine 💬 Spinocerebellar ataxia × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 669. Spinocerebellar ataxia × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
670	Spinocerebellar ataxia 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Spinocerebellar ataxia × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Esketamine hydrochloride 💬 Spinocerebellar ataxia × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 669. Spinocerebellar ataxia × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
671	Spinocerebellar ataxia 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Spinocerebellar ataxia × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine hydrochloride 💬 Spinocerebellar ataxia × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 671. Spinocerebellar ataxia × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
672	Spinocerebellar ataxia 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Spinocerebellar ataxia × Name Full Name GRIN1 glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor GRIN2C glutamate receptor ionotropic, NMDA 2C isoform 1 precursor GRIN2D glutamate receptor ionotropic, NMDA 2D precursor	Ketamine 💬 Spinocerebellar ataxia × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 671. Spinocerebellar ataxia × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
673	Staphylococcus aureus infection 💬	[1] PLG 💬 Staphylococcus aureus infection × Name Full Name PLG plasminogen isoform 1 precursor	Aminocaproic acid 💬 Staphylococcus aureus infection × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 673. Staphylococcus aureus infection × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
674	Staphylococcus aureus infection 💬	[1] PLG 💬 Staphylococcus aureus infection × Name Full Name PLG plasminogen isoform 1 precursor	Tranexamic acid 💬 Staphylococcus aureus infection × Name Other Names Tranexamic acid Cyklokapron Rikavarin Transamin TRANEXAMIC ACID IN SODIUM CHLORIDE	Tranexamic acid	[7] 46, 65, 70, 215, 227, 274, 299 💬 674. Staphylococcus aureus infection × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 215 Tetralogy of Fallot;Fallot tetralogy; 227 Osler disease;Hereditary hemorrhagic telangiectasia;HHT;Osler-Weber-Rendu disease; 274 Osteogenesis Imperfecta; 299 Cystic fibrosis;CF;
675	Synaptic vesicle cycle 💬	[1] SLC6A1 💬 Synaptic vesicle cycle × Name Full Name SLC6A1 sodium- and chloride-dependent GABA transporter 1 isoform a	Gabapentin 💬 Synaptic vesicle cycle × Name Other Names Gabapentin Neurontin Gralise GABARONE RELGAABI	Gabapentin	[7]  6 , 13, 18, 19, 70, 226, 298 💬 675. Synaptic vesicle cycle × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
676	Synaptic vesicle cycle 💬	[1] SNAP25 💬 Synaptic vesicle cycle × Name Full Name SNAP25 synaptosomal-associated protein 25 isoform SNAP25A	Botulinum toxin type A 💬 Synaptic vesicle cycle × Name Other Names Botulinum toxin type A Botox Dysport DAXXIFY	Botulinum toxin type A	[13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬 676. Synaptic vesicle cycle × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  5  Progressive supranuclear palsy;PSP;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 15 Inclusion body myositis; 17 Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome; 47 Buerger disease;Thromboangiitis obliterans; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 171 Wilson disease;WD; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
677	Synaptic vesicle cycle 💬	[1] SNAP25 💬 Synaptic vesicle cycle × Name Full Name SNAP25 synaptosomal-associated protein 25 isoform SNAP25A	Incobotulinumtoxin A 💬 Synaptic vesicle cycle × Name Other Names Incobotulinumtoxin A Onaclostox Xeomin	Botulinum toxin type A	[13]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬 676. Synaptic vesicle cycle × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  5  Progressive supranuclear palsy;PSP;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome;  7  Corticobasal degeneration;Corticobasal syndrome;CBD; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 15 Inclusion body myositis; 17 Multiple system atrophy;MSA;Olivopontocerebellar atrophy;OPCA;Striatonigral degeneration;Shy-Drager syndrome; 47 Buerger disease;Thromboangiitis obliterans; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 171 Wilson disease;WD; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
678	Systemic lupus erythematosus 💬	[1] ELANE 💬 Systemic lupus erythematosus × Name Full Name ELANE neutrophil elastase preproprotein	Ulinastatin 💬 Systemic lupus erythematosus × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 678. Systemic lupus erythematosus × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
679	Systemic lupus erythematosus 💬	[2] GRIN2A, GRIN2B 💬 Systemic lupus erythematosus × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine 💬 Systemic lupus erythematosus × Name Other Names Esketamine Esketamine	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 679. Systemic lupus erythematosus × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
680	Systemic lupus erythematosus 💬	[2] GRIN2A, GRIN2B 💬 Systemic lupus erythematosus × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Esketamine hydrochloride 💬 Systemic lupus erythematosus × Name Other Names Esketamine hydrochloride Spravato	Esketamine	[7]  2 ,  4 ,  6 , 70, 96, 97, 156 💬 679. Systemic lupus erythematosus × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  4  Primary lateral sclerosis;PLS;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 156 Rett syndrome;
681	Systemic lupus erythematosus 💬	[2] GRIN2A, GRIN2B 💬 Systemic lupus erythematosus × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine hydrochloride 💬 Systemic lupus erythematosus × Name Other Names Ketamine hydrochloride Ketalar	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 681. Systemic lupus erythematosus × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
682	Systemic lupus erythematosus 💬	[2] GRIN2A, GRIN2B 💬 Systemic lupus erythematosus × Name Full Name GRIN2A glutamate receptor ionotropic, NMDA 2A isoform 1 precursor GRIN2B glutamate receptor ionotropic, NMDA 2B isoform a precursor	Ketamine 💬 Systemic lupus erythematosus × Name Other Names Ketamine Tekam	Ketamine	[6]  6 , 13, 70, 113, 156, 215 💬 681. Systemic lupus erythematosus × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 70 Spinal stenosis;Extensive spinal canal stenosis; 113 Muscular dystrophy;Dystrophinopathies;Duchenne muscular dystrophy;DMD;Becker muscular dystrophy;BMD;Limb-girdle muscular dystrophy;LGMD;Congenital muscular dystrophy;CMD;Fukuyama-type congenital muscular dystrophy;FCMD;Walker-Warburg syndrome;WWS;Muscle-Eye-Brain disease;MEB disease;α-dystroglycanopathy;Integrin α7 deficient CMD;CIntegrin α7 deficient ongenital muscular dystrophy;Merosin-deficient congenital muscular dystrophy;Ullrich congenital muscular dystrophy;Laminopathy;Rigid spine syndrome;Dynamin 2 deficient congenital muscular dystrophy;Telesonin-deficient congenital muscular dystrophy;Congenital muscular dystrophy with mitochondrial structural abnormalities;Facioscapulohumeral muscular dystrophy;FSMD;Myotonic dystrophy;Dystrophia myotonica;DM;Emery-Dreifuss muscular dystrophy;EDMD;Oculopharyngeal muscular dystrophy;OPMD;Myotilinopathy;Caveolinopathy;Limb gridle muscular dystrophy 1C;LGMD1C;Desminopathy;Sarcoglycanopathy; 156 Rett syndrome; 215 Tetralogy of Fallot;Fallot tetralogy;
683	Taste transduction 💬	[1] CACNA1C 💬 Taste transduction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18	Nicardipine hydrochloride 💬 Taste transduction × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 683. Taste transduction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
684	Taste transduction 💬	[1] CACNA1C 💬 Taste transduction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18	Nicardipine 💬 Taste transduction × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 683. Taste transduction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
685	Taste transduction 💬	[1] CHRM3 💬 Taste transduction × Name Full Name CHRM3 muscarinic acetylcholine receptor M3	Rocuronium bromide 💬 Taste transduction × Name Other Names Rocuronium bromide Zemuron ROCURONIUM	Rocuronium	[2] 70, 296 💬 685. Taste transduction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 296 Biliary atresia;
686	Taste transduction 💬	[2] GABBR1, GABBR2 💬 Taste transduction × Name Full Name GABBR1 gamma-aminobutyric acid type B receptor subunit 1 isoform a precursor GABBR2 gamma-aminobutyric acid type B receptor subunit 2 precursor	Baclofen 💬 Taste transduction × Name Other Names Baclofen Kemstro Lioresal FLEQSUVY GABLOFEN LYVISPAH OZOBAX	Baclofen	[8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 686. Taste transduction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS; 10 Charcot-Marie-Tooth disease;CMT; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 18 Spinocerebellar degeneration;SCD;Spinocerebellar ataxia;SCA;Machado-Joseph disease;MJD;Dentatorubural pallidoluysian atrophy;Dentatorubropallidoluysian atrophy;DRPLA;Naito-Koyanagi disease;Early-onset ataxia with ocular motor ataxia and hypoalbuminemia;EAOH;Ataxia with vitamin E deficiency;AVED;Aprataxin deficiency;APTX deficiency;Friedreich ataxia;FRDA;Senataxin deficiency;SETX deficiency;Autosomal recessive spastic ataxia of Charlevoix-Saguenay;Spastic ataxia; 65 Primary immunodeficiency;X-linked severe combined immunodeficiency;X-SCID;Reticular dysgenesis;Adenosine deaminase deficiency;Omenn syndrome;Purine nucleoside phosphorylase deficiency;CD8 deficiency;ZAP-70 deficiency;MHC class I deficiency;MHC class II deficiency;Other combined immunodeficiencies;Wiskott-Aldrich syndrome;WAS;Ataxia telangiectasia;Nijmegen breakage syndrome;Bloom syndrome;Immunodeficiency, centromere region instability, facial anomalies syndrome;ICF syndrome;PMS2 deficiency;Radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome;RIDDLE syndrome;Schimke syndrome;Netherton syndrome;Thymic hypoplasia;DiGeorge syndrome;22q11.2 deletion syndrome;Hyper-IgE syndrome;Hepatic venoocclusive immunodeficiency;Immunodeficiency with central hepatic vein atresia;Dyskeratosis congenita;X-linked agammaglobulinaemia;Common variable immunodeficiency;Hyper-IgM syndrome;Isolated IgG subclass deficiency;Selective IgA deficiency;Specific antibody production deficiency;Infant transient hypogammaglobulinemia;Other predominantly antibody deficiencies;Chédiak-Higashi syndrome;Chediak-Higashi syndrome;X-linked lymphoproliferative syndrome;SAP deficiency;SH2D1A/SLAM-associated protein deficiency;XIAP deficiency;X-linked inhibitor of apoptosis deficiency;Autoimmune lymphoproliferative syndrome;ALPS;Other diseases of immune dysregulation;Familial hemophagocytic syndrome;FHPS;Familial hemophagocytic lymphohistiocytosis;FHL;Perforin deficiency;Munc13-4 deficiency;Syntaxin 11 deficiency;Munc18-2 deficiency;Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy;APECED;Autoimmune polyglandular syndrome;Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome;IPEX syndrome;CD25 deficiency;ITCH deficiency;Severe congenital neutropenia;Cyclic neutropenia;Other congenital defects of neutrophil function;p14 deficiency;Glycogen storage disease type Ib;Leukocyte adhesion deficiency;Shwachman-Diamond syndrome;Chronic granulomatous disease;Myeloperoxidase deficiency;Mendelian susceptibility to mycobacterial disease;MSMD;Other congenital defects of phagocyte function;Anhidrotic ectodermal dysplasia with immunodeficiency;EDA-ID;Interleukin-1 receptor-associated kinase-4 deficiency;IRAK4 deficiency;MyD88 deficiency;Chronic mucocutaneous candidiasis;Other defects in innate immunity;Warts, hypogammaglobulinemia, infections, myelokathexis syndrome;WHIM syndrome;Congenital complement deficiency;C1q deficiency;C1r deficiency;C1s deficiency;C2 deficiency;C3 deficiency;C4 deficiency;C5 deficiency;C6 deficiency;C7 deficiency;C8 deficiency;C9 deficiency;Hereditary angioedema;C1 inhibitor deficiency;Inherited deficiency of complement system;Factor D deficiency;Factor I deficiency;Factor H deficiency;Properdin deficiency;MASP1 deficiency;MASP2 deficiency;3MC syndrome;Immunodeficiency associated with FCN3 mutation;FCN3; 70 Spinal stenosis;Extensive spinal canal stenosis; 149 Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome; 206 Fragile X syndrome;
687	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Taste transduction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor	Midazolam 💬 Taste transduction × Name Other Names Midazolam Dormicum Buccolam Nayzilam MIDAZOLAM IN SODIUM CHLORIDE N/A MIDAZOLAM IN 0.8% SODIUM CHLORIDE	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 687. Taste transduction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
688	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Taste transduction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor	Midazolam hydrochloride 💬 Taste transduction × Name Other Names Midazolam hydrochloride Versed	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 687. Taste transduction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
689	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Taste transduction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor	Midazolam maleate 💬 Taste transduction × Name Other Names Midazolam maleate Midazolam maleate	Midazolam	[14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬 687. Taste transduction × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 67 Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant polycystic kidney disease;Autosomal dominant PKD;ADPKD;Autosomal recessive polycystic kidney disease;Autosomal recessive PKD;ARPKD; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 231 Alpha-1-antitrypsin deficiency;AATD; 272 Fibrodysplasia ossificans progressiva;FOP; 298 Hereditary pancreatitis;Chronic pancreatitis; 299 Cystic fibrosis;CF;
690	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Taste transduction × Name Full Name GABRA1 gamma-aminobutyric acid receptor subunit alpha-1 precursor GABRA2 gamma-aminobutyric acid receptor subunit alpha-2 isoform a precursor GABRA3 gamma-aminobutyric acid receptor subunit alpha-3 precursor GABRA4 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor GABRA5 gamma-aminobutyric acid receptor subunit alpha-5 precursor GABRA6 gamma-aminobutyric acid receptor subunit alpha-6 precursor	Propofol 💬 Taste transduction × Name Other Names Propofol Diprivan PROPOFOL INJECTABLE EMULSION	Propofol	[10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬 690. Taste transduction × Disease ID Name  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 21 Mitochondrial disease;Choronic progressive external ophthalmolegia;CPEO;Leigh syndrome;Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode;MELAS;Myoclonus epilepsy associated with ragged-red fibers;MERRF;Mitochondrial respiratory chain disorders;Pearson syndrome; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 98 Eosinophilic gastro-intestinal disorder;Eosinophilic gastrointestinal disorder;EGID;Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Neonatal food-protein induced enterocolitis syndrome;Neonatal food-protein induced enterocolitis;N-FPIES;Eosinophilic esophagitis;EoE;Eosinophilic gastroenteritis;EGE; 296 Biliary atresia;
691	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Bupivacaine hydrochloride 💬 Taste transduction × Name Other Names Bupivacaine hydrochloride Bupivacaine hydrochloride hydrate Marcaine BUPIVACAINE HCL MARCAINE SPINAL SENSORCAINE BUPIVACAINE BUPIVACAINE HCI BUPIVACAINE HYDROCHLORIDE INJECTION, SOLUTION BUPIVACAINE HYDROCHLORIDE WITH DEXTROSE BUPIVICAINE HYDROCHLORIDE SENSORCAINE MPF	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 691. Taste transduction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
692	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Bupivacaine 💬 Taste transduction × Name Other Names Bupivacaine Bucaine Exparel	Bupivacaine	[10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬 691. Taste transduction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 53 Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;Autoimmune exocrinopathy; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 298 Hereditary pancreatitis;Chronic pancreatitis;
693	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Lidocaine 💬 Taste transduction × Name Other Names Lidocaine Dentipatch Xylocaine BONDLIDO LIDODERM ZTLIDO LIDOCAINE 5% LIDOCAINE 5% PATCH LIDOCAINE PATCH LIDOCAN LIDOCAN III LIDOCAN IV LIDOCAN V LIDOCAN VI LIDOCAN VII LIDOX 5 PATCH TRIDACAINE II TRIDACAINE III TRIDACAINE XL	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 693. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
694	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Lidocaine hydrochloride 💬 Taste transduction × Name Other Names Lidocaine hydrochloride Dalcaine Xylocaine AKTEN LIDOCAINE LIDOCAINE HCI LIDOCAINE HYDROCHLORIDE AND DEXTROSE XYLOCAIN XYLOCAINE MPF XYLOCAINE- MPF 0.5% LIDOCAINE HCL GLYDO GLYDO- LIDOCAINE HYDROCHLORIDE JELLY LIDOCAINE HCL LIDOCAINE VISCOUS	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 693. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
695	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Lidocaine hydrochloride monohydrate 💬 Taste transduction × Name Other Names Lidocaine hydrochloride monohydrate Lidocaine Zingo	Lidocaine	[14]  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬 693. Taste transduction × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 22 Moyamoya disease;Occlusive disease in circle of Willis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 168 Ehlers-Danlos syndrome;EDS;Classic EDS;Classical EDS;cEDS;Classical-like Ehlers-Danlos syndrome;Classical-like EDS;clEDS;Cardiac-valvular Ehlers-Danlos syndrome;cvEDS;Vascular Ehlers-Danlos syndrome;Vascular EDS;vEDS;Hypermobile Ehlers-Danlos syndrome;Hypermobile EDS;hEDS;Arthrochalasia Ehlers-Danlos syndrome;Arthrochalasia EDS;aEDS;Dermatosparaxis Ehlers-Danlos syndrome;Dermatosparaxis EDS;dEDS;Kyphoscoliosis Ehlers-Danlos syndrome;Kyphoscoliosis EDS;kEDS;Brittle cornea syndrome;BCS;Spondylodysplastic Ehlers-Danlos Syndrome;spEDS;Musculocontractural Ehlers-Danlos Syndrome;mEDS;D4ST1-deficient Ehlers-Danlos syndrome;Dermatan 4-0-sulfotransferase 1-deficient EDS;D4ST1-deficient EDS;DDEDS;Myopathic Ehlers-Danlos Syndrome;mEDS;Periodontal Ehlers-Danlos Syndrome;pEDS; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 298 Hereditary pancreatitis;Chronic pancreatitis;
696	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Ropivacaine hydrochloride 💬 Taste transduction × Name Other Names Ropivacaine hydrochloride Ropivacaine hydrochloride hydrate Anapeine NAROPIN	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 696. Taste transduction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
697	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬 Taste transduction × Name Full Name SCN2A sodium channel protein type 2 subunit alpha isoform 1 SCN3A sodium channel protein type 3 subunit alpha isoform 2 SCN9A sodium channel protein type 9 subunit alpha isoform 2	Ropivacaine 💬 Taste transduction × Name Other Names Ropivacaine Naropin	Ropivacaine	[7] 22, 36, 46, 63, 70, 71, 97 💬 696. Taste transduction × Disease ID Name 22 Moyamoya disease;Occlusive disease in circle of Willis; 36 Epidermolysis bullosa;Kindler syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 71 Idiopathic osteonecrosis of the femoral head;Idiopathic femoral head necrosis;Osteonecrosis of the femoral head; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
698	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 beta-3 adrenergic receptor	Epinephrine 💬 Thermogenesis × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 698. Thermogenesis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
699	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 beta-3 adrenergic receptor	Epinephrine hydrochloride 💬 Thermogenesis × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 698. Thermogenesis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
700	Thermogenesis 💬	[1] ADRB3 💬 Thermogenesis × Name Full Name ADRB3 beta-3 adrenergic receptor	Epinephrine bitartrate 💬 Thermogenesis × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 698. Thermogenesis × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
701	Tight junction 💬	[1] CACNA1D 💬 Tight junction × Name Full Name CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Tight junction × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 701. Tight junction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
702	Tight junction 💬	[1] CACNA1D 💬 Tight junction × Name Full Name CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Tight junction × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 701. Tight junction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
703	TNF signaling pathway 💬	[1] PTGS2 💬 TNF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 TNF signaling pathway × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 703. TNF signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
704	TNF signaling pathway 💬	[1] PTGS2 💬 TNF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 TNF signaling pathway × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 704. TNF signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
705	TNF signaling pathway 💬	[1] PTGS2 💬 TNF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 TNF signaling pathway × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 705. TNF signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
706	TNF signaling pathway 💬	[1] PTGS2 💬 TNF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 TNF signaling pathway × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 706. TNF signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
707	TNF signaling pathway 💬	[1] PTGS2 💬 TNF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 TNF signaling pathway × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 706. TNF signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
708	Transcriptional misregulation in cancer 💬	[1] ELANE 💬 Transcriptional misregulation in cancer × Name Full Name ELANE neutrophil elastase preproprotein	Ulinastatin 💬 Transcriptional misregulation in cancer × Name Other Names Ulinastatin Miraclid	Ulinastatin	[1] 70 💬 708. Transcriptional misregulation in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
709	Transcriptional misregulation in cancer 💬	[1] PLAT 💬 Transcriptional misregulation in cancer × Name Full Name PLAT tissue-type plasminogen activator isoform 1 preproprotein	Aminocaproic acid 💬 Transcriptional misregulation in cancer × Name Other Names Aminocaproic acid Epsilon-Aminocaproic acid Amicar	Aminocaproic acid	[1] 70 💬 709. Transcriptional misregulation in cancer × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis;
710	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬 Type II diabetes mellitus × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine hydrochloride 💬 Type II diabetes mellitus × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 710. Type II diabetes mellitus × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
711	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬 Type II diabetes mellitus × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b	Nicardipine 💬 Type II diabetes mellitus × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 710. Type II diabetes mellitus × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
712	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Epinephrine 💬 Vascular smooth muscle contraction × Name Other Names Epinephrine Adrenaline Auvi-q Epipen ADRENALIN ADRENALIN VIALS ADRENALIN(R) EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL NEFFY EPINEPHRINE 0.15 PEDIATRICS EPINEPHRINE 0.3 ADULTS EPINEPHRINE PEDIATRICS	Epinephrine	[4] 46, 70, 96, 97 💬 712. Vascular smooth muscle contraction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
713	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Epinephrine hydrochloride 💬 Vascular smooth muscle contraction × Name Other Names Epinephrine hydrochloride Adrenalin chloride	Epinephrine	[4] 46, 70, 96, 97 💬 712. Vascular smooth muscle contraction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
714	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬 Vascular smooth muscle contraction × Name Full Name ADRA1A alpha-1A adrenergic receptor isoform 1 ADRA1B alpha-1B adrenergic receptor ADRA1D alpha-1D adrenergic receptor	Epinephrine bitartrate 💬 Vascular smooth muscle contraction × Name Other Names Epinephrine bitartrate Adrenaline bitartrate Asmatane mist Medihaler-epi EPINEPHRINE	Epinephrine	[4] 46, 70, 96, 97 💬 712. Vascular smooth muscle contraction × Disease ID Name 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD;
715	Vascular smooth muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Vascular smooth muscle contraction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine hydrochloride 💬 Vascular smooth muscle contraction × Name Other Names Nicardipine hydrochloride Cardene CARDENE IV NICARDIPINE HYDROCHLORIDE IN SODIUM CHLORIDE	Nicardipine	[2] 70, 86 💬 715. Vascular smooth muscle contraction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
716	Vascular smooth muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Vascular smooth muscle contraction × Name Full Name CACNA1C voltage-dependent L-type calcium channel subunit alpha-1C isoform 18 CACNA1D voltage-dependent L-type calcium channel subunit alpha-1D isoform b CACNA1F voltage-dependent L-type calcium channel subunit alpha-1F isoform 1 CACNA1S voltage-dependent L-type calcium channel subunit alpha-1S	Nicardipine 💬 Vascular smooth muscle contraction × Name Other Names Nicardipine Cardene	Nicardipine	[2] 70, 86 💬 715. Vascular smooth muscle contraction × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 86 Pulmonary arterial hypertension;PAH;
717	Vascular smooth muscle contraction 💬	[1] PTGIR 💬 Vascular smooth muscle contraction × Name Full Name PTGIR prostacyclin receptor	Selexipag 💬 Vascular smooth muscle contraction × Name Other Names Selexipag Uptravi	Selexipag	[6] 47, 51, 70, 84, 86, 88 💬 717. Vascular smooth muscle contraction × Disease ID Name 47 Buerger disease;Thromboangiitis obliterans; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 70 Spinal stenosis;Extensive spinal canal stenosis; 84 Sarcoidosis; 86 Pulmonary arterial hypertension;PAH; 88 Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;
718	VEGF signaling pathway 💬	[1] PTGS2 💬 VEGF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Acetaminophen 💬 VEGF signaling pathway × Name Other Names Acetaminophen Paracetamol Tylenol	Acetaminophen	[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬 718. VEGF signaling pathway × Disease ID Name 11 Myasthenia gravis;MG; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 19 Lysosomal storage disease;Lysosomal disease;Gaucher disease;Niemann-Pick disease type A/B;Niemann-Pick type A;NPD-A;NPA;Niemann-Pick type B;NPD-B;NPB;Acid sphingomyelinase deficiency;ASMD;Niemann-Pick disease type C;Niemann-Pick type C;NPD-C;NPC;GM1-gangliosidosis;GM1-gangliosidoses;GM2-gangliosidosis;GM2-gangliosidoses;Tay-Sachs disease;Sandhoff disease;Krabbe disease;Krabbe syndrome;Metachromatic leukodystrophy;MLD;Multiple-sulfatase deficiency;Farber disease;Mucopolysaccharidosis type I;Mucopolysaccharidosis I;MPS I;Hurler syndrome;Hurler-Scheie syndrome;Scheie syndrome;Mucopolysaccharidosis type II;Mucopolysaccharidosis II;MPS II;Hunter syndrome;Mucopolysaccharidosis type III;Mucopolysaccharidosis III;MPS III;Sanfilippo syndrome;Mucopolysaccharidosis type IV;Mucopolysaccharidosis IV;MPS IV;MPS IVA;Morquio syndrome;Morquio A syndrome;Mucopolysaccharidosis type VI;Mucopolysaccharidosis VI;MPS VI;Maroteaux-Lamy syndrome;Mucopolysaccharidosis type VII;Mucopolysaccharidosis VII;MPS VII;Sly syndrome;Mucopolysaccharidosis type IX;Mucopolysaccharidosis IX;MPS IX;Hyaluronidase deficiency;Sialidosis;Galactosialidosis;Mucolipidosis II;Mucolipidosis type II;I-cell disease;Mucolipidosis III;Mucolipidosis type III;Alpha-Mannosidosis;Alpha-Mannosidase Deficiency;Beta-Mannosidosis;Beta-Mannosidase Deficiency;Fucosidosis;Aspartylglucosaminuria;Schindler disease;Schindler syndrome;Kanzaki disease;Kanzaki syndrome;Pompe disease;Pompe syndrome;Acid lipase deficiency;Wolman disease;Cholesterol ester storage disease;Danon disease;Danon syndrome;Free sialic acid storage disease;Infantile sialic acid storage disease;ISSD;Salla disease;Salla syndrome;Ceroid lipofuscinosis;Fabry disease;Cystinosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 35 Pemphigus; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 49 Systemic lupus erythematosus;SLE; 51 Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc; 63 Idiopathic thrombocytopenic purpura;Immune thrombocytopenia;Primary immune thrombocytopenia;Autoimmune thrombocytopenic purpura;Immune thrombocytopenic purpura; 70 Spinal stenosis;Extensive spinal canal stenosis; 77 Growth hormone secreting pituitary adenoma;Excessive secretion of growth hormone;Pituitary growth hormone secretion hyperthyroidism;Acromegaly; 86 Pulmonary arterial hypertension;PAH; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 222 Primary nephrotic syndrome;Nephrotic syndrome;Glomerulonephritis;Minimal change nephrotic syndrome;MCNS;Membranous nephropathy;Focal segmental glomerulosclerosis;FSGS;Crescentic glomerulonephritis;CGN;CrGN;Endocapillary proliferative glomerulonephritis; 231 Alpha-1-antitrypsin deficiency;AATD; 256 Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;Glycogen storage disease type 0;GSD0;Glycogen synthase deficiency;Glycogen storage disease type II;GSDII;Pompe disease;Pompe syndrome;Alpha-1,4-glucosidase acid deficiency;Glycogen storage disease type III;GSDIII;Cori disease;Cori syndrome;Forbes disease;Forbes syndrome;Glycogen debranching enzyme deficiency;Glycogen storage disease type IV;GSDIV;Andersen disease;Glycogen-branching enzyme deficiency;GBED;Glycogen storage disease type V;GSDV;McArdle disease;Muscle phosphorylase deficiency;Muscular phosphorylase deficiency;Glycogen storage disease type VII;GSDVII;Tarui disease;Tarui syndrome;Phosphofructokinase deficiency;PFK deficiency;Glycogen storage disease type IXd;GSDIXd;Phosphorylase kinase deficiency;Phosphoglycerate kinase deficiency;PGK deficiency;Glycogen storage disease type X;GSDX;Phosphoglycerate mutase deficiency;Glycogen storage diseass type XI;GSDXI;Kanno disease;Lactate dehydrogenase deficiency;Glycogen storage diseass type XII;GSDXII;Aldolase A deficiency;Glycogen storage diseass type XIII;GSDXIII;Beta-enolase deficiency;Glycogen storage diseass type XIV;GSDXIV;Phosphoglucomutase deficiency;Glycogen storage diseass type XV;GSDXV;Glycogenin 1 deficiency; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica; 300 IgG4-related disease;Immunoglobulin G4-related disease;IgG4-related disease;Autoimmune pancreatitis;IgG4-related sclerosing cholangitis;IgG4-related lacrimal gland, orbital, and salivary gland lesions;IgG4-related kidney disease; 337 Homocystinuria;Homocystinuria type I;Cystathionine beta-synthase deficiency;CBS deficiency;Homocystinuria type II;Homocystinuria cblC type;Cobalamin C deficiency;cblC deficiency;Homocystinuria type III;Methylenetetrahydrofolate reductase deficiency;MTHFR deficiency;
719	VEGF signaling pathway 💬	[1] PTGS2 💬 VEGF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Celecoxib 💬 VEGF signaling pathway × Name Other Names Celecoxib Celebrex Onsenal ELYXYB - CELECOXIB VYSCOXA CELECOXIB 200 MG	Celecoxib	[14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬 719. VEGF signaling pathway × Disease ID Name  2  Amyotrophic lateral sclerosis;ALS;  3  Spinal muscular atrophy;SMA;Myelopathic muscular atrophy;Werdnig-Hoffman disease;Dubowitz disease;Kugelberg-Welander disease;Dubowitz syndrome;  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 13 Multiple sclerosis/Neuromyelitis optica;Multiple sclerosis;Neuromyelitis optica;Neuromyelitis optica spectrum disorder;NMOSD;Balo concentric sclerosis;Baló concentric sclerosis; 34 Neurofibromatosis;Neurofibromatosis type 1;NF1;Recklinghausen disease;Neurofibromatosis type 2;NF2; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 89 Lymphangioleiomyomatosis;LAM; 96 Crohn disease;CD;Terminal ileitis;Inflammatory bowel disease;IBD; 97 Ulcerative colitis;UC;Inflammatory bowel disease;IBD; 107 Juvenile idiopathic arthritis;JIA;Systemic juvenile idiopathic arthritis;Systemic-onset juvenile idiopathic arthritis;sJIA;Joint-type juvenile idiopathic arthritis;Joint-type juvenile idiopathic arthritis;Joint-type JIA; 161 Familial benign chronic pemphigus;Benign familial pemphigus;Hailey-Hailey disease; 171 Wilson disease;WD; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
720	VEGF signaling pathway 💬	[1] PTGS2 💬 VEGF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Etoricoxib 💬 VEGF signaling pathway × Name Other Names Etoricoxib Etoricoxib	Etoricoxib	[5]  6 , 46, 70, 165, 271 💬 720. VEGF signaling pathway × Disease ID Name  6  Parkinson disease;Disease Parkinson's;Parkinson syndrome;Parkinsonian syndrome; 46 Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;Systemic rheumatoid vasculitis;SRV; 70 Spinal stenosis;Extensive spinal canal stenosis; 165 Pachydermoperiostosis;PDP;Primary hypertrophic osteoarthropathy;PHO; 271 Ankylosing spondylitis;Spondylarthritis ankylopoietica;
721	VEGF signaling pathway 💬	[1] PTGS2 💬 VEGF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac tromethamine 💬 VEGF signaling pathway × Name Other Names Ketorolac tromethamine Acular Toradol ACULAR LS ACUVAIL SPRIX	Ketorolac	[2] 70, 226 💬 721. VEGF signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
722	VEGF signaling pathway 💬	[1] PTGS2 💬 VEGF signaling pathway × Name Full Name PTGS2 prostaglandin G/H synthase 2 precursor	Ketorolac 💬 VEGF signaling pathway × Name Other Names Ketorolac Toradol	Ketorolac	[2] 70, 226 💬 721. VEGF signaling pathway × Disease ID Name 70 Spinal stenosis;Extensive spinal canal stenosis; 226 Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Back to top