Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 57 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
AXL [3] AXL, KDR, MET 💬
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Cabozantinib Cabozantinib 💬EGFR tyrosine kinase inhibitor resistance
| Cabozantinib | 034 [1] 34 💬1. EGFR tyrosine kinase inhibitor resistance
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| 2 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BCL2 [1] BCL2 💬EGFR tyrosine kinase inhibitor resistance
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Venetoclax Venetoclax 💬EGFR tyrosine kinase inhibitor resistance
| Venetoclax | 028 [1] 28 💬2. EGFR tyrosine kinase inhibitor resistance
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| 3 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF [1] BRAF 💬EGFR tyrosine kinase inhibitor resistance
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Dabrafenib Dabrafenib 💬EGFR tyrosine kinase inhibitor resistance
| Dabrafenib | 034 [1] 34 💬3. EGFR tyrosine kinase inhibitor resistance
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| 4 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF [4] BRAF, KDR, PDGFRB, RAF1 💬
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Sorafenib Sorafenib 💬EGFR tyrosine kinase inhibitor resistance
| Sorafenib | 034 [2] 34, 86 💬
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| 5 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [1] EGFR 💬EGFR tyrosine kinase inhibitor resistance
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Cetuximab Cetuximab 💬EGFR tyrosine kinase inhibitor resistance
| Cetuximab | 051 [2] 51, 86 💬
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| 6 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [1] EGFR 💬EGFR tyrosine kinase inhibitor resistance
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Erlotinib Erlotinib 💬EGFR tyrosine kinase inhibitor resistance
| Erlotinib | 094 [1] 94 💬6. EGFR tyrosine kinase inhibitor resistance
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| 7 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [1] EGFR 💬EGFR tyrosine kinase inhibitor resistance
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Gefitinib Gefitinib 💬EGFR tyrosine kinase inhibitor resistance
| Gefitinib | 075 [1] 75 💬7. EGFR tyrosine kinase inhibitor resistance
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| 8 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [1] EGFR 💬EGFR tyrosine kinase inhibitor resistance
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Icotinib Icotinib 💬EGFR tyrosine kinase inhibitor resistance
| Icotinib | 034 [1] 34 💬8. EGFR tyrosine kinase inhibitor resistance
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| 9 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [2] EGFR, ERBB2 💬
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Lapatinib Lapatinib 💬EGFR tyrosine kinase inhibitor resistance
| Lapatinib | 034 [3] 34, 74, 75 💬
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| 10 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [2] EGFR, ERBB2 💬
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Neratinib Neratinib 💬EGFR tyrosine kinase inhibitor resistance
| Neratinib | 034 [1] 34 💬10. EGFR tyrosine kinase inhibitor resistance
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