Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Human papillomavirus infection 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬
2 Human papillomavirus infection 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬
3 Human papillomavirus infection 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬
4 Human papillomavirus infection 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
5 Human papillomavirus infection 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
6 Human papillomavirus infection 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
7 Human papillomavirus infection 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
8 Human papillomavirus infection 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
9 Human papillomavirus infection 💬
 [2] HDAC1, HDAC2 💬 Vorinostat 💬 Vorinostat [2] 75, 96 💬
10 Human papillomavirus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab [1] 49 💬
11 Human papillomavirus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab [1] 49 💬
12 Human papillomavirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
13 Human papillomavirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
14 Human papillomavirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
15 Human papillomavirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
16 Human papillomavirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
17 Human papillomavirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
18 Human papillomavirus infection 💬
 [2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
19 Human papillomavirus infection 💬
 [1] ITGA4 💬 Firategrast 💬 Firategrast [1] 13 💬
20 Human papillomavirus infection 💬
 [1] ITGA4 💬 Natalizumab 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
21 Human papillomavirus infection 💬
 [2] ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab [2] 96, 97 💬
22 Human papillomavirus infection 💬
 [2] ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
23 Human papillomavirus infection 💬
 [1] ITGB7 💬 Etrolizumab 💬 Etrolizumab [2] 96, 97 💬
24 Human papillomavirus infection 💬
 [1] JAK1 💬 Abrocitinib 💬 Abrocitinib [1] 84 💬
25 Human papillomavirus infection 💬
 [1] JAK1 💬 Baricitinib 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
26 Human papillomavirus infection 💬
 [1] JAK1 💬 Filgotinib 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
27 Human papillomavirus infection 💬
 [1] JAK1 💬 Itacitinib 💬 Itacitinib [4] 46, 51, 97, 228 💬
28 Human papillomavirus infection 💬
 [1] JAK1 💬 Peficitinib 💬 Peficitinib [1] 46 💬
29 Human papillomavirus infection 💬
 [1] JAK1 💬 Ruxolitinib 💬 Ruxolitinib [3] 60, 65, 228 💬
30 Human papillomavirus infection 💬
 [1] JAK1 💬 Upadacitinib 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
31 Human papillomavirus infection 💬
 [2] JAK1, TYK2 💬 Tofacitinib 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
32 Human papillomavirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
33 Human papillomavirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
34 Human papillomavirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
35 Human papillomavirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
36 Human papillomavirus infection 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
37 Human papillomavirus infection 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
38 Human papillomavirus infection 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
39 Human papillomavirus infection 💬
 [1] MTOR 💬 Temsirolimus 💬 Temsirolimus [1] 13 💬
40 Human papillomavirus infection 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
41 Human papillomavirus infection 💬
 [1] PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
42 Human papillomavirus infection 💬
 [1] PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
43 Human papillomavirus infection 💬
 [1] PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
44 Human papillomavirus infection 💬
 [1] PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
45 Human papillomavirus infection 💬
 [1] PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
46 Human papillomavirus infection 💬
 [2] PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
47 Human papillomavirus infection 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
48 Human papillomavirus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
49 Human papillomavirus infection 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
50 Human papillomavirus infection 💬
 [1] PSEN1 💬 Tarenflurbil 💬 Tarenflurbil [1] 13 💬
51 Human papillomavirus infection 💬
 [1] PTGER4 💬 Misoprostol 💬 Misoprostol [3] 46, 70, 271 💬
52 Human papillomavirus infection 💬
 [1] PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
53 Human papillomavirus infection 💬
 [1] PTGS2 💬 Acetaminophen 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
54 Human papillomavirus infection 💬
 [1] PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
55 Human papillomavirus infection 💬
 [1] PTGS2 💬 Celecoxib 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
56 Human papillomavirus infection 💬
 [1] PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
57 Human papillomavirus infection 💬
 [1] PTGS2 💬 Diflunisal 💬 Diflunisal [1] 28 💬
58 Human papillomavirus infection 💬
 [1] PTGS2 💬 Etodolac 💬 Etodolac [1] 46 💬
59 Human papillomavirus infection 💬
 [1] PTGS2 💬 Etoricoxib 💬 Etoricoxib [2] 46, 271 💬
60 Human papillomavirus infection 💬
 [1] PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
61 Human papillomavirus infection 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
62 Human papillomavirus infection 💬
 [1] PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
63 Human papillomavirus infection 💬
 [1] PTGS2 💬 Ketoprofen 💬 Ketoprofen [1] 46 💬
64 Human papillomavirus infection 💬
 [1] PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
65 Human papillomavirus infection 💬
 [1] PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
66 Human papillomavirus infection 💬
 [1] PTGS2 💬 Lumiracoxib 💬 Lumiracoxib [1] 46 💬
67 Human papillomavirus infection 💬
 [1] PTGS2 💬 Meloxicam 💬 Meloxicam [4] 46, 49, 271, 296 💬
68 Human papillomavirus infection 💬
 [1] PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
69 Human papillomavirus infection 💬
 [1] PTGS2 💬 Nimesulide 💬 Nimesulide [1] 46 💬
70 Human papillomavirus infection 💬
 [1] PTGS2 💬 Parecoxib 💬 Parecoxib [2] 46, 271 💬
71 Human papillomavirus infection 💬
 [1] PTGS2 💬 Rofecoxib 💬 Rofecoxib [1] 46 💬
72 Human papillomavirus infection 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
73 Human papillomavirus infection 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬
74 Human papillomavirus infection 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬
75 Human papillomavirus infection 💬
 [1] PTGS2 💬 Valdecoxib 💬 Valdecoxib [1] 46 💬
76 Human papillomavirus infection 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬
77 Human papillomavirus infection 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
78 Human papillomavirus infection 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
79 Human papillomavirus infection 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
80 Human papillomavirus infection 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
81 Human papillomavirus infection 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
82 Human papillomavirus infection 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
83 Human papillomavirus infection 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬
84 Human papillomavirus infection 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬
85 Human papillomavirus infection 💬
 [1] TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
86 Human papillomavirus infection 💬
 [1] TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
87 Human papillomavirus infection 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
88 Human papillomavirus infection 💬
 [1] TYK2 💬 Deucravacitinib 💬 Deucravacitinib [3] 49, 96, 97 💬
89 Human papillomavirus infection 💬
 [1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
90 Human papillomavirus infection 💬
 [1] VEGFA 💬 Bevacizumab 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
91 Human papillomavirus infection 💬
 [1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬
92 Human papillomavirus infection 💬
 [1] VWF 💬 Caplacizumab 💬 Caplacizumab [1] 64 💬