Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Angiotensin II 💬 Angiotensin II [7] 17, 46, 49, 66, 218, 222, 224 💬
2 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Angiotensin II 💬 Angiotensin II [7] 17, 46, 49, 66, 218, 222, 224 💬
3 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II [7] 17, 46, 49, 66, 218, 222, 224 💬
4 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Azilsartan medoxomil 💬 Azilsartan medoxomil [1] 66 💬
5 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Azilsartan 💬 Azilsartan medoxomil [1] 66 💬
6 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Azilsartan kamedoxomil 💬 Azilsartan medoxomil [1] 66 💬
7 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Buloxibutid 💬 Buloxibutid [1] 85 💬
8 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid [1] 85 💬
9 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
10 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Irbesartan 💬 Irbesartan [4] 66, 167, 168, 222 💬
11 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Losartan potassium 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
12 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
13 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Sparsentan 💬 Sparsentan [3] 66, 218, 222 💬
14 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
15 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Valsartan 💬 Valsartan [8] 57, 58, 66, 75, 86, 210, 222, 224 💬
16 Phospholipase D signaling pathway 💬
 [3] AVPR1A, AVPR1B, AVPR2 💬 Terlipressin 💬 Terlipressin [1] 299 💬
17 Phospholipase D signaling pathway 💬
 [3] AVPR1A, AVPR1B, AVPR2 💬 Terlipressin acetate 💬 Terlipressin [1] 299 💬
18 Phospholipase D signaling pathway 💬
 [3] AVPR1A, AVPR1B, AVPR2 💬 Vasopressin 💬 Vasopressin [2] 210, 225 💬
19 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 Desmopressin 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
20 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 Desmopressin acetate 💬 Desmopressin [6]  6 , 64, 72, 75, 225, 288 💬
21 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 Lixivaptan 💬 Lixivaptan [1] 67 💬
22 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 Tolvaptan 💬 Tolvaptan [4] 67, 72, 86, 225 💬
23 Phospholipase D signaling pathway 💬
 [1] CXCR1 💬 Eltrekibart 💬 Eltrekibart [1] 97 💬
24 Phospholipase D signaling pathway 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
25 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Afatinib 💬 Afatinib [1] 285 💬
26 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
27 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
28 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib [2] 94, 160 💬
29 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [2] 94, 160 💬
30 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
31 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
32 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
33 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
34 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
35 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
36 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
37 Phospholipase D signaling pathway 💬
 [1] F2 💬 Dabigatran 💬 Dabigatran [5] 51, 75, 85, 91, 124 💬
38 Phospholipase D signaling pathway 💬
 [1] F2 💬 Dabigatran etexilate mesylate 💬 Dabigatran etexilate [2] 51, 75 💬
39 Phospholipase D signaling pathway 💬
 [1] F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate [2] 51, 75 💬
40 Phospholipase D signaling pathway 💬
 [1] F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa [1] 85 💬
41 Phospholipase D signaling pathway 💬
 [1] FCER1A 💬 Omalizumab 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
42 Phospholipase D signaling pathway 💬
 [3] FYN, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
43 Phospholipase D signaling pathway 💬
 [3] FYN, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
44 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
45 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
46 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin human 💬 Insulin human [1] 156 💬
47 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin lispro 💬 Insulin lispro [1] 53 💬
48 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Barzolvolimab 💬 Barzolvolimab [1] 98 💬
49 Phospholipase D signaling pathway 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
50 Phospholipase D signaling pathway 💬
 [2] KIT, PDGFRA 💬 Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
51 Phospholipase D signaling pathway 💬
 [2] KIT, PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
52 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 Catequentinib 💬 Anlotinib [1] 85 💬
53 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
54 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
55 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
56 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
57 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRB, RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
58 Phospholipase D signaling pathway 💬
 [3] KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
59 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
60 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
61 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib [1] 280 💬
62 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [4] 34, 278, 279, 280 💬
63 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
64 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib [1] 34 💬
65 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
66 Phospholipase D signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
67 Phospholipase D signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
68 Phospholipase D signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [46]  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
69 Phospholipase D signaling pathway 💬
 [1] MTOR 💬 Temsirolimus 💬 Temsirolimus [4] 13, 34, 89, 331 💬
70 Phospholipase D signaling pathway 💬
 [2] PDGFRA, PDGFRB 💬 Nintedanib esylate 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
71 Phospholipase D signaling pathway 💬
 [2] PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
72 Phospholipase D signaling pathway 💬
 [2] PDGFRA, PDGFRB 💬 Seralutinib 💬 Seralutinib [1] 86 💬
73 Phospholipase D signaling pathway 💬
 [1] PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib [4] 138, 278, 279, 280 💬
74 Phospholipase D signaling pathway 💬
 [1] PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib [2] 53, 65 💬
75 Phospholipase D signaling pathway 💬
 [1] PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
76 Phospholipase D signaling pathway 💬
 [2] PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib [1] 121 💬
77 Phospholipase D signaling pathway 💬
 [3] PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
78 Phospholipase D signaling pathway 💬
 [1] PTGFR 💬 Tafluprost 💬 Tafluprost [1] 299 💬
79 Phospholipase D signaling pathway 💬
 [1] PTGFR 💬 Isopropyl unoprostone 💬 Unoprostone [1] 90 💬
80 Phospholipase D signaling pathway 💬
 [1] PTGFR 💬 Unoprostone 💬 Unoprostone [1] 90 💬
81 Phospholipase D signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
82 Phospholipase D signaling pathway 💬
 [1] SYK 💬 Fostamatinib disodium 💬 Fostamatinib [5] 46, 49, 61, 63, 66 💬
83 Phospholipase D signaling pathway 💬
 [1] SYK 💬 Gusacitinib 💬 Gusacitinib [1] 49 💬