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Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

Adrenergic signaling in cardiomyocytes 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

Aldosterone synthesis and secretion 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Alzheimer disease 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Alzheimer disease 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Alzheimer disease 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Alzheimer disease 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Alzheimer disease 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Alzheimer disease 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Alzheimer disease 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

Alzheimer disease 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

Alzheimer disease 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

Arrhythmogenic right ventricular cardiomyopathy 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

Calcium signaling pathway 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Calcium signaling pathway 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Calcium signaling pathway 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Calcium signaling pathway 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

Calcium signaling pathway 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

Calcium signaling pathway 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

Calcium signaling pathway 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Calcium signaling pathway 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Calcium signaling pathway 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

Calcium signaling pathway 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

Calcium signaling pathway 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

100

Calcium signaling pathway 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

101

Calcium signaling pathway 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

102

Calcium signaling pathway 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

103

Calcium signaling pathway 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

104

Calcium signaling pathway 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

105

Calcium signaling pathway 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

106

Calcium signaling pathway 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

107

Calcium signaling pathway 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

108

Calcium signaling pathway 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

109

Calcium signaling pathway 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

110

Calcium signaling pathway 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

111

cAMP signaling pathway 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

112

cAMP signaling pathway 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

113

cAMP signaling pathway 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

114

cAMP signaling pathway 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

115

cAMP signaling pathway 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

116

cAMP signaling pathway 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

117

cAMP signaling pathway 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

118

cAMP signaling pathway 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

119

cAMP signaling pathway 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

120

cAMP signaling pathway 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

121

cAMP signaling pathway 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

122

cAMP signaling pathway 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

123

cAMP signaling pathway 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

124

cAMP signaling pathway 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

125

cAMP signaling pathway 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

126

cAMP signaling pathway 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

127

cAMP signaling pathway 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

128

cAMP signaling pathway 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

129

cAMP signaling pathway 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

130

cAMP signaling pathway 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

131

cAMP signaling pathway 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

132

cAMP signaling pathway 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

133

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

134

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

135

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

136

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

137

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

138

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

139

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

140

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

141

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

142

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

143

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

144

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

145

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

146

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

147

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

148

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

149

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

150

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

151

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

152

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

153

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

154

Cardiac muscle contraction 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

155

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

156

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

157

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

158

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

159

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

160

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

161

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

162

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

163

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

164

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

165

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

166

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

167

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

168

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

169

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

170

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

171

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

172

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

173

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

174

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

175

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

176

cGMP-PKG signaling pathway 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

177

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

178

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

179

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

180

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

181

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

182

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

183

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

184

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

185

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

186

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

187

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

188

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

189

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

190

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

191

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

192

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

193

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

194

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

195

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

196

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

197

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

198

Chemical carcinogenesis - receptor activation 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

199

Cholinergic synapse 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

200

Cholinergic synapse 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

201

Cholinergic synapse 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

202

Cholinergic synapse 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

203

Cholinergic synapse 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

204

Cholinergic synapse 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

205

Cholinergic synapse 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

206

Cholinergic synapse 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

207

Cholinergic synapse 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

208

Cholinergic synapse 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

209

Cholinergic synapse 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

210

Cholinergic synapse 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

211

Cholinergic synapse 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

212

Cholinergic synapse 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

213

Cholinergic synapse 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

214

Cholinergic synapse 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

215

Cholinergic synapse 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

216

Cholinergic synapse 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

217

Cholinergic synapse 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

218

Cholinergic synapse 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

219

Cholinergic synapse 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

220

Cholinergic synapse 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

221

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

222

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

223

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

224

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

225

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

226

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

227

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

228

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

229

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

230

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

231

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

232

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

233

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

234

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

235

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

236

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

237

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

238

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

239

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

240

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

241

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

242

Cortisol synthesis and secretion 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

243

Cushing syndrome 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

244

Cushing syndrome 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

245

Cushing syndrome 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

246

Cushing syndrome 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

247

Cushing syndrome 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

248

Cushing syndrome 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

249

Cushing syndrome 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

250

Cushing syndrome 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

251

Cushing syndrome 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

252

Cushing syndrome 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

253

Cushing syndrome 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

254

Cushing syndrome 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

255

Cushing syndrome 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

256

Cushing syndrome 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

257

Cushing syndrome 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

258

Cushing syndrome 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

259

Cushing syndrome 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

260

Cushing syndrome 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

261

Cushing syndrome 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

262

Cushing syndrome 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

263

Cushing syndrome 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

264

Cushing syndrome 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

265

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

266

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

267

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

268

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

269

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

270

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

271

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

272

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

273

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

274

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

275

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

276

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

277

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

278

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

279

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

280

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

281

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

282

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

283

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

284

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

285

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

286

Dilated cardiomyopathy 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

287

GABAergic synapse 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

288

GABAergic synapse 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

289

GABAergic synapse 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

290

GABAergic synapse 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

291

GABAergic synapse 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

292

GABAergic synapse 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

293

GABAergic synapse 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

294

GABAergic synapse 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

295

GABAergic synapse 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

296

GABAergic synapse 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

297

GABAergic synapse 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

298

GABAergic synapse 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

299

GABAergic synapse 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

300

GABAergic synapse 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

301

GABAergic synapse 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

302

GABAergic synapse 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

303

GABAergic synapse 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

304

GABAergic synapse 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

305

GABAergic synapse 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

306

GABAergic synapse 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

307

GABAergic synapse 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

308

GABAergic synapse 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

309

GnRH secretion 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

310

GnRH secretion 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

311

GnRH secretion 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

312

GnRH secretion 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

313

GnRH secretion 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

314

GnRH secretion 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

315

GnRH secretion 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

316

GnRH secretion 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

317

GnRH secretion 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

318

GnRH secretion 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

319

GnRH secretion 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

320

GnRH secretion 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

321

GnRH secretion 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

322

GnRH secretion 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

323

GnRH secretion 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

324

GnRH secretion 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

325

GnRH secretion 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

326

GnRH secretion 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

327

GnRH secretion 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

328

GnRH secretion 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

329

GnRH secretion 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

330

GnRH secretion 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

331

GnRH signaling pathway 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

332

GnRH signaling pathway 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

333

GnRH signaling pathway 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

334

GnRH signaling pathway 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

335

GnRH signaling pathway 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

336

GnRH signaling pathway 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

337

GnRH signaling pathway 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

338

GnRH signaling pathway 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

339

GnRH signaling pathway 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

340

GnRH signaling pathway 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

341

GnRH signaling pathway 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

342

GnRH signaling pathway 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

343

GnRH signaling pathway 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

344

GnRH signaling pathway 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

345

GnRH signaling pathway 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

346

GnRH signaling pathway 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

347

GnRH signaling pathway 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

348

GnRH signaling pathway 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

349

GnRH signaling pathway 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

350

GnRH signaling pathway 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

351

GnRH signaling pathway 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

352

GnRH signaling pathway 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

353

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

354

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

355

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

356

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

357

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

358

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

359

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

360

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

361

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

362

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

363

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

364

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

365

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

366

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

367

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

368

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

369

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

370

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

371

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

372

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

373

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

374

Growth hormone synthesis, secretion and action 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

375

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

376

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

377

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

378

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

379

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

380

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

381

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

382

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

383

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

384

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

385

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

386

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

387

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

388

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

389

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

390

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

391

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

392

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

393

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

394

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

395

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

396

Hypertrophic cardiomyopathy 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

397

Insulin secretion 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

398

Insulin secretion 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

399

Insulin secretion 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

400

Insulin secretion 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

401

Insulin secretion 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

402

Insulin secretion 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

403

Insulin secretion 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

404

Insulin secretion 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

405

Insulin secretion 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

406

Insulin secretion 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

407

Insulin secretion 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

408

Insulin secretion 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

409

Insulin secretion 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

410

Insulin secretion 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

411

Insulin secretion 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

412

Insulin secretion 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

413

Insulin secretion 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

414

Insulin secretion 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

415

Insulin secretion 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

416

Insulin secretion 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

417

Insulin secretion 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

418

Insulin secretion 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

419

MAPK signaling pathway 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

420

MAPK signaling pathway 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

421

MAPK signaling pathway 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

422

MAPK signaling pathway 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

423

MAPK signaling pathway 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

424

MAPK signaling pathway 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

425

MAPK signaling pathway 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

426

MAPK signaling pathway 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

427

MAPK signaling pathway 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

428

MAPK signaling pathway 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

429

MAPK signaling pathway 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

430

MAPK signaling pathway 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

431

MAPK signaling pathway 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

432

MAPK signaling pathway 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

433

MAPK signaling pathway 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

434

MAPK signaling pathway 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

435

MAPK signaling pathway 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

436

MAPK signaling pathway 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

437

MAPK signaling pathway 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

438

MAPK signaling pathway 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

439

MAPK signaling pathway 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

440

MAPK signaling pathway 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

441

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

442

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

443

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

444

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

445

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

446

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

447

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

448

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

449

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

450

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

451

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

452

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

453

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

454

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

455

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

456

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

457

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

458

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

459

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

460

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

461

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

462

Oxytocin signaling pathway 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

463

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

464

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

465

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

466

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

467

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

468

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

469

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

470

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

471

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

472

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

473

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

474

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

475

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

476

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

477

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

478

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

479

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

480

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

481

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

482

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

483

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

484

Pathways of neurodegeneration - multiple diseases 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

485

Prion disease 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

486

Prion disease 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

487

Prion disease 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

488

Prion disease 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

489

Prion disease 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

490

Prion disease 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

491

Prion disease 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

492

Prion disease 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

493

Prion disease 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

494

Prion disease 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

495

Prion disease 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

496

Prion disease 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

497

Prion disease 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

498

Prion disease 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

499

Prion disease 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

500

Prion disease 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

501

Prion disease 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

502

Prion disease 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

503

Prion disease 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

504

Prion disease 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

505

Prion disease 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

506

Prion disease 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

507

Renin secretion 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

508

Renin secretion 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

509

Renin secretion 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

510

Renin secretion 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

511

Renin secretion 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

512

Renin secretion 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

513

Renin secretion 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

514

Renin secretion 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

515

Renin secretion 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

516

Renin secretion 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

517

Renin secretion 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

518

Renin secretion 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

519

Renin secretion 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

520

Renin secretion 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

521

Renin secretion 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

522

Renin secretion 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

523

Renin secretion 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

524

Renin secretion 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

525

Renin secretion 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

526

Renin secretion 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

527

Renin secretion 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

528

Renin secretion 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

529

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

530

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

531

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

532

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

533

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

534

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

535

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

536

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

537

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

538

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

539

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

540

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

541

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

542

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

543

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

544

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

545

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

546

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

547

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

548

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

549

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

550

Retrograde endocannabinoid signaling 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

551

Serotonergic synapse 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

552

Serotonergic synapse 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

553

Serotonergic synapse 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

554

Serotonergic synapse 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

555

Serotonergic synapse 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

556

Serotonergic synapse 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

557

Serotonergic synapse 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

558

Serotonergic synapse 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

559

Serotonergic synapse 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

560

Serotonergic synapse 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

561

Serotonergic synapse 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

562

Serotonergic synapse 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

563

Serotonergic synapse 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

564

Serotonergic synapse 💬

[1] CACNA1S 💬

Nilvadipine 💬

Nilvadipine

[1] 90 💬

565

Serotonergic synapse 💬

[1] CACNA1S 💬

Perhexiline maleate 💬

Perhexiline

[2] 58, 272 💬

566

Serotonergic synapse 💬

[1] CACNA1S 💬

Perhexiline 💬

Perhexiline

[2] 58, 272 💬

567

Serotonergic synapse 💬

[1] CACNA1S 💬

Pinaverium bromide 💬

Pinaverium

[1] 298 💬

568

Serotonergic synapse 💬

[1] CACNA1S 💬

Propiverine hydrochloride 💬

Propiverine

[1] 226 💬

569

Serotonergic synapse 💬

[1] CACNA1S 💬

Propiverine 💬

Propiverine

[1] 226 💬

570

Serotonergic synapse 💬

[1] CACNA1S 💬

Topiramate 💬

Topiramate

[5] 6 , 140, 144, 156, 193 💬

571

Serotonergic synapse 💬

[1] CACNA1S 💬

Verapamil hydrochloride 💬

Verapamil

[4] 58, 96, 140, 167 💬

572

Serotonergic synapse 💬

[1] CACNA1S 💬

Verapamil 💬

Verapamil

[4] 58, 96, 140, 167 💬

573

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Amlodipine besylate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

574

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Amlodipine maleate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

575

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Amlodipine 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

576

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Amlodipine benzoate 💬

Amlodipine

[3] 51, 67, 298 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;Autosomal dominant PKD;ADPKD;Autosomal recessive PKD;ARPKD;
298	Hereditary pancreatitis;Chronic pancreatitis;

577

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Bevantolol hydrochloride 💬

Bevantolol

[1] 8 💬

578

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Cilnidipine 💬

Cilnidipine

[1] 67 💬

579

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Diltiazem hydrochloride 💬

Name	Other Names
Diltiazem hydrochloride	Diltiazem hydrochloride (JP18/USP) Cardizem (TN) Cartia XT (TN) Dilacor XR (TN) Dilt-CD (TN) CARDIZEM CARDIZEM CD CARDIZEM LA DILTIAZEM HCL CD DILTIAZEM HYDROCHLORIDE IN SODIUM CHLORIDE TIAZAC CARTIA CARTIA XT DILTIAZEM HCI DILTIAZEM HCL ER DILTIAZEM HYDROCHLORIDE DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE MATZIM LA TIADYLT ER

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

580

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Diltiazem malate 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

581

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Diltiazem 💬

Diltiazem

[4] 51, 58, 86, 88 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;Diffuse cutaneous SSc;dcSSc;Limited cutaneous SSc;lcSSc;
58	Hypertrophic cardiomyopathy;HCM;
86	Pulmonary arterial hypertension;PAH;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;

582

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Isradipine 💬

Isradipine

[1] 6 💬

583

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Nicardipine hydrochloride 💬

Nicardipine

[2] 70, 86 💬

584

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

585

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬

Nifedipine 💬

Nifedipine

[1] 81 💬

Disease ID	Name
81	Congenital adrenal hyperplasia;CAH;Congenital adrenal enzyme deficiency;Congenial adrenal cortex enzyme deficiency;Congenital Lipoid Adrenal Hyperplasia;3β-Hydroxysteroid Dehydrogenase Deficiency;21-Hydroxylase deficiency;21-OHD;11β-Hydroxylase deficiency;17α-Hydroxylase deficiency;P450 oxidoreductase deficiency;

586

Vascular smooth muscle contraction 💬

[1] CACNA1S 💬