Drug Description in Trials / DrugBank / KEGG DRUG

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DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

[1] Amlodipine 💬

[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬

Name	Full Name
CACNA1C	calcium voltage-gated channel subunit alpha1 C
CACNA1D	calcium voltage-gated channel subunit alpha1 D
CACNA1F	calcium voltage-gated channel subunit alpha1 F
CACNA1S	calcium voltage-gated channel subunit alpha1 S

[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, ...

[4] 13, 51, 67, 298 💬

2

Atorvastatin
(PMS-amlodipine-atorvastatin)

[3] Atorvastatin; Atorvastatin Calcium; Lipitor

[1] Atorvastatin 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
58	Hypertrophic cardiomyopathy
63	Idiopathic thrombocytopenic purpura
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
88	Chronic thromboembolic pulmonary hypertension
93	Primary biliary cholangitis
96	Crohn disease
97	Ulcerative colitis
160	Congenital ichthyosis
222	Primary nephrotic syndrome
225	Congenital nephrogenic diabetes insipidus
265	Lipodystrophy
271	Ankylosing spondylitis
297	Alagille syndrome
299	Cystic fibrosis

3

Benazepril
(Amlodipine and Benazepril Hydrochloride)

[1] Benazepril 💬

[1] ACE 💬

[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...

[4] 49, 57, 218, 224 💬

4

Hydrochlorothiazide
(Olmesartan Medoxomil / Amlodipine Besylate / Hydrochlorothiazide)

[2] Esidrix; HYDROCHLOROTHIAZIDE

[1] Hydrochlorothiazide 💬

[1] SLC12A3 💬

-

[4] 13, 67, 225, 235 💬

5

Perindopril
(Apo-perindopril/amlodipine)

[2] Coversyl; Perindopril

[1] Perindopril 💬

[1] ACE 💬

[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...

[4] 58, 113, 167, 222 💬

6

Telmisartan
(Telmisartan and Amlodipine)

[1] Telmisartan

[1] Telmisartan 💬

[1] AGTR1 💬

[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, A ...

[2] 66, 67 💬

7

Valsartan
(Amlodipine and Valsartan)

[3] Diovan; Entresto; Valsartan

[1] Valsartan 💬

[1] AGTR1 💬

[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, A ...

[7] 57, 58, 66, 75, 218, 222, 224 💬

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