Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
2 Alcoholism 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
3 Alcoholism 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
4 Alcoholism 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
5 Alcoholism 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
6 Alcoholism 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
7 Alcoholism 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
8 Alcoholism 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
9 Alzheimer disease 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
10 Alzheimer disease 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
11 Alzheimer disease 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
12 Alzheimer disease 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
13 Alzheimer disease 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
14 Alzheimer disease 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
15 Alzheimer disease 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
16 Alzheimer disease 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
17 Amphetamine addiction 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
18 Amphetamine addiction 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
19 Amphetamine addiction 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
20 Amphetamine addiction 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
21 Amphetamine addiction 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
22 Amphetamine addiction 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
23 Amphetamine addiction 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
24 Amphetamine addiction 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
25 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
26 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
27 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
28 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
29 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
30 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
31 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
32 Amyotrophic lateral sclerosis 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
33 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
34 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
35 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
36 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
37 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
38 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
39 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
40 Calcium signaling pathway 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
41 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
42 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
43 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
44 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
45 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
46 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
47 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
48 cAMP signaling pathway 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
49 Circadian entrainment 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
50 Circadian entrainment 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
51 Circadian entrainment 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
52 Circadian entrainment 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
53 Circadian entrainment 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
54 Circadian entrainment 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
55 Circadian entrainment 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
56 Circadian entrainment 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
57 Cocaine addiction 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
58 Cocaine addiction 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
59 Cocaine addiction 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
60 Cocaine addiction 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
61 Cocaine addiction 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
62 Cocaine addiction 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
63 Cocaine addiction 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
64 Cocaine addiction 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
65 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
66 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
67 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
68 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
69 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
70 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
71 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
72 Glutamatergic synapse 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
73 Long-term potentiation 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
74 Long-term potentiation 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
75 Long-term potentiation 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
76 Long-term potentiation 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
77 Long-term potentiation 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
78 Long-term potentiation 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
79 Long-term potentiation 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
80 Long-term potentiation 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
81 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
82 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
83 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
84 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
85 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
86 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
87 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
88 Neuroactive ligand-receptor interaction 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
89 Nicotine addiction 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
90 Nicotine addiction 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
91 Nicotine addiction 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
92 Nicotine addiction 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
93 Nicotine addiction 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
94 Nicotine addiction 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
95 Nicotine addiction 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
96 Nicotine addiction 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
97 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
98 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
99 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
100 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
101 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
102 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
103 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
104 Pathways of neurodegeneration - multiple diseases 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
105 Prion disease 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
106 Prion disease 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
107 Prion disease 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
108 Prion disease 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
109 Prion disease 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
110 Prion disease 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
111 Prion disease 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
112 Prion disease 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
113 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Acamprosate 💬 Acamprosate [2]  6 , 206 💬
114 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Amantadine 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
115 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
116 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬
117 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
118 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Latrepirdine 💬 Latrepirdine [1]  8  💬
119 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Memantine 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
120 Spinocerebellar ataxia 💬
 [1] GRIN2D 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬

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