DDrare
Disease
Drug
Target Gene/Pathway
Contact
JA
Drug
Description in Trials
/
DrugBank
/
KEGG DRUG
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
drugs per page:
Showing 1 to 5 of 5 drugs
Filter by
Reset
|
No.
DrugBank
Drug (Description in trials)
KEGG DRUG
KEGG GENES
KEGG PATHWAY
Disease ID
1
Acetaminophen
(Acetaminophen
Dextromethorphan
HBr Guaifenesin Phenylephrine HCl)
[4]
Acetaminophen
Acetaminophen
;
Paracetamol
;
Tylenol
;
Ultracet
[1]
Acetaminophen
Acetaminophen
💬
1. Acetaminophen
×
Name
Other Names
Acetaminophen
Acetaminophen (JP18/USP)
Paracetamol (INN)
Tylenol (TN)
OFIRMEV
GOOD NEIGHBOR PHARMACY PAIN RELIEF
[2]
PTGS1
PTGS1
,
PTGS2
💬
1. Acetaminophen
×
Name
Full Name
PTGS1
prostaglandin-endoperoxide synthase 1
PTGS2
prostaglandin-endoperoxide synthase 2
[23]
Alzheimer disease
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemical carcinogenesis - DNA adducts
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
IL-17 signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Metabolic pathways
,
MicroRNAs in cancer
,
NF-kappa B signaling pathway
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Platelet activation
,
Regulation of lipolysis in adipocytes
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Small cell lung cancer
,
TNF signaling pathway
,
VEGF signaling pathway
💬
[23]
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemi
...
[15]
3
3
,
6
,
11
,
13
,
34
,
35
,
46
,
49
,
51
,
70
,
86
,
222
,
256
,
271
,
337
💬
1. Acetaminophen
×
Disease ID
Name
3
Spinal muscular atrophy
6
Parkinson disease
11
Myasthenia gravis
13
Multiple sclerosis/Neuromyelitis optica
34
Neurofibromatosis
35
Pemphigus
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
70
Spinal stenosis
86
Pulmonary arterial hypertension
222
Primary nephrotic syndrome
256
Muscle glycogenosis
271
Ankylosing spondylitis
337
Homocystinuria
2
Dextromethorphan
[4]
Dextromethorphan
Dextromethorphan
;
Dextromethorphan hydrobromide
;
Dextrometorfano
;
Nuedexta
[1]
Dextromethorphan
Dextromethorphan
💬
2.
Dextromethorphan
×
Name
Other Names
Dextromethorphan
Dextromethorphan (USP)
[6]
GRIN1
GRIN1
,
GRIN2A
,
GRIN2B
,
GRIN2C
,
GRIN2D
,
SIGMAR1
💬
2.
Dextromethorphan
×
Name
Full Name
GRIN1
glutamate ionotropic receptor NMDA type subunit 1
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C
glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D
glutamate ionotropic receptor NMDA type subunit 2D
SIGMAR1
sigma non-opioid intracellular receptor 1
[20]
Alcoholism
Alcoholism
,
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Calcium signaling pathway
,
Circadian entrainment
,
Cocaine addiction
,
Dopaminergic synapse
,
Glutamatergic synapse
,
Huntington disease
,
Long-term potentiation
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Spinocerebellar ataxia
,
Systemic lupus erythematosus
,
cAMP signaling pathway
💬
[20]
Alcoholism
,
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Calcium si
...
[11]
2
2
,
6
,
8
,
13
,
21
,
46
,
78
,
85
,
96
,
97
,
156
💬
2.
Dextromethorphan
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
6
Parkinson disease
8
Huntington disease
13
Multiple sclerosis/Neuromyelitis optica
21
Mitochondrial disease
46
Malignant rheumatoid arthritis
78
Hypopituitarism
85
Idiopathic interstitial pneumonia
96
Crohn disease
97
Ulcerative colitis
156
Rett syndrome
3
Phenylephrine
(Acetaminophen
Dextromethorphan
HBr Guaifenesin Phenylephrine HCl)
[1]
Phenylephrine
Phenylephrine
[1]
Phenylephrine
Phenylephrine
💬
3. Phenylephrine
×
Name
Other Names
Phenylephrine
Phenylephrine (INN)
Phenylephrine Minims (TN)
[3]
ADRA1A
ADRA1A
,
ADRA1B
,
ADRA1D
💬
3. Phenylephrine
×
Name
Full Name
ADRA1A
adrenoceptor alpha 1A
ADRA1B
adrenoceptor alpha 1B
ADRA1D
adrenoceptor alpha 1D
[7]
AMPK signaling pathway
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
,
Salivary secretion
,
Vascular smooth muscle contraction
,
cGMP-PKG signaling pathway
💬
[7]
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Calcium signaling pathway
,
Neuro
...
[1]
22
22
💬
3. Phenylephrine
×
Disease ID
Name
22
Moyamoya disease
4
Promethazine
(Promethazine HCl and
Dextromethorphan
Hydrobromide)
[1]
Promethazine
Promethazine
[1]
Promethazine
Promethazine
💬
4. Promethazine
×
Name
Other Names
Promethazine
Promethazine (JAN/INN)
[1]
HRH1
HRH1
💬
4. Promethazine
×
Name
Full Name
HRH1
histamine receptor H1
[3]
Calcium signaling pathway
Calcium signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Neuroactive ligand-receptor interaction
💬
[3]
Calcium signaling pathway
,
Inflammatory mediator regulation of TRP channels
,
Neuroactive ligand-
...
[1]
96
96
💬
4. Promethazine
×
Disease ID
Name
96
Crohn disease
5
Pseudoephedrine
(Acetaminophen/
dextromethorphan
/pseudoephedrine)
[1]
Pseudoephedrine
Pseudoephedrine
[1]
Pseudoephedrine
Pseudoephedrine
💬
5. Pseudoephedrine
×
Name
Other Names
Pseudoephedrine
Pseudoephedrine (INN)
Neodurasina (TN)
Acunaso (TN)
[9]
ADRA1A
ADRA1A
,
ADRA1B
,
ADRA1D
,
ADRA2A
,
ADRA2B
,
ADRA2C
,
ADRB1
,
ADRB2
,
ADRB3
💬
5. Pseudoephedrine
×
Name
Full Name
ADRA1A
adrenoceptor alpha 1A
ADRA1B
adrenoceptor alpha 1B
ADRA1D
adrenoceptor alpha 1D
ADRA2A
adrenoceptor alpha 2A
ADRA2B
adrenoceptor alpha 2B
ADRA2C
adrenoceptor alpha 2C
ADRB1
adrenoceptor beta 1
ADRB2
adrenoceptor beta 2
ADRB3
adrenoceptor beta 3
[14]
AMPK signaling pathway
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Calcium signaling pathway
,
Chemical carcinogenesis - receptor activation
,
Dilated cardiomyopathy
,
Gap junction
,
Neuroactive ligand-receptor interaction
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Thermogenesis
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
[14]
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Calcium signaling pathway
,
Chem
...
[1]
17
17
💬
5. Pseudoephedrine
×
Disease ID
Name
17
Multiple system atrophy