Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [1] HRH1 💬 Cetirizine hydrochloride 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
2 Calcium signaling pathway 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
3 Calcium signaling pathway 💬
 [1] HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine [1] 14 💬
4 Calcium signaling pathway 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
5 Calcium signaling pathway 💬
 [1] HRH1 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
6 Calcium signaling pathway 💬
 [1] HRH1 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
7 Calcium signaling pathway 💬
 [1] HRH1 💬 Clemastine fumarate 💬 Clemastine [2] 13, 179 💬
8 Calcium signaling pathway 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [2] 13, 179 💬
9 Calcium signaling pathway 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
10 Calcium signaling pathway 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [1] 13 💬
11 Calcium signaling pathway 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
12 Calcium signaling pathway 💬
 [1] HRH1 💬 Diphenhydramine hydrochloride 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
13 Calcium signaling pathway 💬
 [1] HRH1 💬 Diphenhydramine salicylate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
14 Calcium signaling pathway 💬
 [1] HRH1 💬 Diphenhydramine citrate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
15 Calcium signaling pathway 💬
 [1] HRH1 💬 Doxepin hydrochloride 💬 Doxepin [1]  6  💬
16 Calcium signaling pathway 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
17 Calcium signaling pathway 💬
 [1] HRH1 💬 Fexofenadine hydrochloride 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
18 Calcium signaling pathway 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
19 Calcium signaling pathway 💬
 [1] HRH1 💬 Histamine phosphate 💬 Histamine [1] 13 💬
20 Calcium signaling pathway 💬
 [1] HRH1 💬 Histamine 💬 Histamine [1] 13 💬
21 Calcium signaling pathway 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
22 Calcium signaling pathway 💬
 [1] HRH1 💬 Levocetirizine dihydrochloride 💬 Levocetirizine [1] 61 💬
23 Calcium signaling pathway 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [5] 13, 19, 46, 89, 98 💬
24 Calcium signaling pathway 💬
 [1] HRH1 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
25 Calcium signaling pathway 💬
 [1] HRH1 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
26 Calcium signaling pathway 💬
 [1] HRH1 💬 Promethazine hydrochloride 💬 Promethazine [2]  6 , 96 💬
27 Calcium signaling pathway 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [2]  6 , 96 💬
28 Calcium signaling pathway 💬
 [1] HRH1 💬 Promethazine teoclate 💬 Promethazine [2]  6 , 96 💬
29 Calcium signaling pathway 💬
 [1] HRH1 💬 Rupatadine 💬 Rupatadine [1] 46 💬
30 Calcium signaling pathway 💬
 [1] HRH1 💬 Rupatadine fumarate 💬 Rupatadine [1] 46 💬
31 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Cetirizine hydrochloride 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
32 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
33 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine [1] 14 💬
34 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
35 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
36 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
37 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Clemastine fumarate 💬 Clemastine [2] 13, 179 💬
38 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [2] 13, 179 💬
39 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
40 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [1] 13 💬
41 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
42 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Diphenhydramine hydrochloride 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
43 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Diphenhydramine salicylate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
44 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Diphenhydramine citrate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
45 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Doxepin hydrochloride 💬 Doxepin [1]  6  💬
46 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
47 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Fexofenadine hydrochloride 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
48 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
49 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Histamine phosphate 💬 Histamine [1] 13 💬
50 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Histamine 💬 Histamine [1] 13 💬
51 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
52 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Levocetirizine dihydrochloride 💬 Levocetirizine [1] 61 💬
53 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [5] 13, 19, 46, 89, 98 💬
54 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
55 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
56 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Promethazine hydrochloride 💬 Promethazine [2]  6 , 96 💬
57 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [2]  6 , 96 💬
58 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Promethazine teoclate 💬 Promethazine [2]  6 , 96 💬
59 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Rupatadine 💬 Rupatadine [1] 46 💬
60 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 Rupatadine fumarate 💬 Rupatadine [1] 46 💬
61 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Cetirizine hydrochloride 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
62 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
63 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine [1] 14 💬
64 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
65 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
66 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
67 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Clemastine fumarate 💬 Clemastine [2] 13, 179 💬
68 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [2] 13, 179 💬
69 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
70 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [1] 13 💬
71 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
72 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Diphenhydramine hydrochloride 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
73 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Diphenhydramine salicylate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
74 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Diphenhydramine citrate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
75 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Doxepin hydrochloride 💬 Doxepin [1]  6  💬
76 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
77 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Fexofenadine hydrochloride 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
78 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
79 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Histamine phosphate 💬 Histamine [1] 13 💬
80 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Histamine 💬 Histamine [1] 13 💬
81 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
82 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Levocetirizine dihydrochloride 💬 Levocetirizine [1] 61 💬
83 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [5] 13, 19, 46, 89, 98 💬
84 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
85 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
86 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Promethazine hydrochloride 💬 Promethazine [2]  6 , 96 💬
87 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [2]  6 , 96 💬
88 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Promethazine teoclate 💬 Promethazine [2]  6 , 96 💬
89 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Rupatadine 💬 Rupatadine [1] 46 💬
90 Neuroactive ligand signaling 💬
 [1] HRH1 💬 Rupatadine fumarate 💬 Rupatadine [1] 46 💬
91 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Cetirizine hydrochloride 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
92 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Cetirizine 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
93 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine [1] 14 💬
94 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
95 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
96 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬
97 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Clemastine fumarate 💬 Clemastine [2] 13, 179 💬
98 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Clemastine 💬 Clemastine [2] 13, 179 💬
99 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Desloratadine 💬 Desloratadine [1] 13 💬
100 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine [1] 13 💬
101 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Diphenhydramine 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
102 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Diphenhydramine hydrochloride 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
103 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Diphenhydramine salicylate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
104 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Diphenhydramine citrate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
105 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Doxepin hydrochloride 💬 Doxepin [1]  6  💬
106 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Doxepin 💬 Doxepin [1]  6  💬
107 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Fexofenadine hydrochloride 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
108 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Fexofenadine 💬 Fexofenadine [4]  6 , 13, 19, 46 💬
109 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Histamine phosphate 💬 Histamine [1] 13 💬
110 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Histamine 💬 Histamine [1] 13 💬
111 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Levocetirizine 💬 Levocetirizine [1] 61 💬
112 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Levocetirizine dihydrochloride 💬 Levocetirizine [1] 61 💬
113 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Loratadine 💬 Loratadine [5] 13, 19, 46, 89, 98 💬
114 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
115 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Olanzapine pamoate 💬 Olanzapine [2]  2 ,  8  💬
116 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Promethazine hydrochloride 💬 Promethazine [2]  6 , 96 💬
117 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Promethazine 💬 Promethazine [2]  6 , 96 💬
118 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Promethazine teoclate 💬 Promethazine [2]  6 , 96 💬
119 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Rupatadine 💬 Rupatadine [1] 46 💬
120 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 Rupatadine fumarate 💬 Rupatadine [1] 46 💬

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