Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Retrograde endocannabinoid signaling 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
2 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
3 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
4 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
5 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine [6] 51, 67, 79, 113, 222, 298 💬
6 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Benidipine hydrochloride 💬 Benidipine [1] 57 💬
7 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Benidipine 💬 Benidipine [1] 57 💬
8 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol [1]  8  💬
9 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem [4] 51, 58, 86, 88 💬
10 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem [4] 51, 58, 86, 88 💬
11 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem [4] 51, 58, 86, 88 💬
12 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine [1]  6  💬
13 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine [2] 70, 86 💬
14 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine [2] 70, 86 💬
15 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine [2] 50, 81 💬
16 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine [1] 90 💬
17 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline [2] 58, 272 💬
18 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
19 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine [1] 226 💬
20 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine [1] 226 💬
21 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil [5] 57, 58, 96, 140, 167 💬
22 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil [5] 57, 58, 96, 140, 167 💬
23 Retrograde endocannabinoid signaling 💬
 [24] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
24 Retrograde endocannabinoid signaling 💬
 [1] CACNA1S 💬 Pinaverium bromide 💬 Pinaverium [1] 298 💬
25 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 Cannabidiol 💬 Cannabidiol [20]  6 ,  8 , 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
26 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 Dronabinol 💬 Dronabinol [5]  2 , 13, 46, 271, 298 💬
27 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 Nabilone 💬 Nabilone [4]  6 , 13, 97, 127 💬
28 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 Rimonabant 💬 Rimonabant [1] 193 💬
29 Retrograde endocannabinoid signaling 💬
 [1] GABRA1 💬 Etomidate 💬 Etomidate [2]  6 , 11 💬
30 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Alprazolam 💬 Alprazolam [2]  8 , 75 💬
31 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Clobazam 💬 Clobazam [2] 140, 144 💬
32 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Clonazepam 💬 Clonazepam [1]  6  💬
33 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Diazepam 💬 Diazepam [3] 46, 155, 298 💬
34 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Eszopiclone 💬 Eszopiclone [3]  6 , 13, 46 💬
35 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬
36 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Fospropofol disodium 💬 Fospropofol [1] 226 💬
37 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
38 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
39 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Lorazepam 💬 Lorazepam [2] 36, 231 💬
40 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
41 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam hydrochloride 💬 Midazolam [14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
42 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam maleate 💬 Midazolam [14]  2 ,  3 ,  6 , 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
43 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Nitrazepam 💬 Nitrazepam [1] 145 💬
44 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Propofol 💬 Propofol [10]  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬
45 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Remimazolam besylate 💬 Remimazolam [3]  6 , 22, 97 💬
46 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Remimazolam 💬 Remimazolam [3]  6 , 22, 97 💬
47 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zolpidem tartrate 💬 Zolpidem [3]  5 ,  6 , 46 💬
48 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem [3]  5 ,  6 , 46 💬
49 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Zopiclone 💬 Zopiclone [1]  6  💬
50 Retrograde endocannabinoid signaling 💬
 [1] GABRA5 💬 Alogabat 💬 Alogabat [1] 201 💬
51 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel 💬 Perampanel [3]  2 ,  6 , 144 💬
52 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel hydrate 💬 Perampanel [3]  2 ,  6 , 144 💬
53 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Riluzole 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
54 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Talampanel 💬 Talampanel [2]  2 ,  6  💬
55 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Troriluzole 💬 Troriluzole [1] 18 💬
56 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 Troriluzole hydrochloride 💬 Troriluzole [1] 18 💬
57 Retrograde endocannabinoid signaling 💬
 [2] KCNJ3, KCNJ5 💬 Amiodarone hydrochloride 💬 Amiodarone [3] 28, 67, 127 💬
58 Retrograde endocannabinoid signaling 💬
 [2] KCNJ3, KCNJ5 💬 Amiodarone 💬 Amiodarone [3] 28, 67, 127 💬
59 Retrograde endocannabinoid signaling 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
60 Retrograde endocannabinoid signaling 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
61 Retrograde endocannabinoid signaling 💬
 [1] PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin [1] 168 💬
62 Retrograde endocannabinoid signaling 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
63 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Aceclofenac 💬 Aceclofenac [1] 46 💬
64 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Acemetacin 💬 Acemetacin [1] 271 💬
65 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Acetaminophen 💬 Acetaminophen [19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
66 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Aspirin 💬 Acetylsalicylic acid [5] 13, 46, 51, 62, 210 💬
67 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Celecoxib 💬 Celecoxib [14]  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
68 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Diclofenac potassium 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
69 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Diclofenac sodium 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
70 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Diclofenac 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
71 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Diclofenac diethylamine 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
72 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Diclofenac epolamine 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
73 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Diflunisal 💬 Diflunisal [1] 28 💬
74 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Etodolac 💬 Etodolac [1] 46 💬
75 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Etoricoxib 💬 Etoricoxib [5]  6 , 46, 70, 165, 271 💬
76 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
77 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Flurbiprofen sodium 💬 Flurbiprofen [3] 13, 21, 46 💬
78 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [8] 13, 46, 65, 96, 107, 113, 271, 299 💬
79 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ibuprofen aluminum 💬 Ibuprofen [8] 13, 46, 65, 96, 107, 113, 271, 299 💬
80 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ibuprofen lysine 💬 Ibuprofen [8] 13, 46, 65, 96, 107, 113, 271, 299 💬
81 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen [8] 13, 46, 65, 96, 107, 113, 271, 299 💬
82 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen [8] 13, 46, 65, 96, 107, 113, 271, 299 💬
83 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Indobufen 💬 Indobufen [1] 222 💬
84 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
85 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Indomethacin sodium 💬 Indomethacin [3] 225, 271, 298 💬
86 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ketoprofen 💬 Ketoprofen [2] 13, 46 💬
87 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ketoprofen lysine 💬 Ketoprofen [2] 13, 46 💬
88 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ketoprofen sodium 💬 Ketoprofen [2] 13, 46 💬
89 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ketorolac tromethamine 💬 Ketorolac [2] 70, 226 💬
90 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ketorolac 💬 Ketorolac [2] 70, 226 💬
91 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
92 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Lumiracoxib 💬 Lumiracoxib [1] 46 💬
93 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Meloxicam 💬 Meloxicam [4] 46, 49, 271, 296 💬
94 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
95 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Naproxen sodium 💬 Naproxen [4] 13, 46, 107, 271 💬
96 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Nimesulide 💬 Nimesulide [1] 46 💬
97 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Valdecoxib 💬 Parecoxib [3] 46, 71, 271 💬
98 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Parecoxib 💬 Parecoxib [3] 46, 71, 271 💬
99 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Parecoxib sodium 💬 Parecoxib [3] 46, 71, 271 💬
100 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Rofecoxib 💬 Rofecoxib [1] 46 💬
101 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Sodium salicylate 💬 Salicylic acid [1] 97 💬
102 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Salsalate 💬 Salsalate [1]  5  💬
103 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Sulindac 💬 Sulindac [1] 206 💬
104 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid [1]  5  💬