Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Melanogenesis 💬
 [1] EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2 Melanogenesis 💬
 [1] EDNRB 💬 Bosentan 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
3 Melanogenesis 💬
 [1] EDNRB 💬 Macitentan 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
4 Melanogenesis 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
5 Melanogenesis 💬
 [1] KIT 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
6 Melanogenesis 💬
 [1] KIT 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
7 Melanogenesis 💬
 [1] KIT 💬 Masitinib 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
8 Melanogenesis 💬
 [1] KIT 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
9 Melanogenesis 💬
 [1] KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
10 Melanogenesis 💬
 [1] KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
11 Melanogenesis 💬
 [2] KIT, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
12 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
13 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
14 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
15 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
16 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
17 Melanogenesis 💬
 [1] MC1R 💬 Afamelanotide 💬 Afamelanotide [3] 159, 161, 254 💬
18 Melanogenesis 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬