Target Gene/Pathway Pathway / Gene


Search results


No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Proteoglycans in cancer 💬
[1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 Proteoglycans in cancer 💬
[1] BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib [1] 34 💬
3 Proteoglycans in cancer 💬
[3] BRAF, KDR, RAF1 💬 Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
4 Proteoglycans in cancer 💬
[3] BRAF, KDR, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
5 Proteoglycans in cancer 💬
[1] EGFR 💬 Cetuximab 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
6 Proteoglycans in cancer 💬
[1] EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib [2] 94, 160 💬
7 Proteoglycans in cancer 💬
[1] EGFR 💬 Erlotinib 💬 Erlotinib [2] 94, 160 💬
8 Proteoglycans in cancer 💬
[1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
9 Proteoglycans in cancer 💬
[1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
10 Proteoglycans in cancer 💬
[2] EGFR, ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
11 Proteoglycans in cancer 💬
[2] EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
12 Proteoglycans in cancer 💬
[3] EGFR, ERBB2, ERBB4 💬 Afatinib 💬 Afatinib [1] 285 💬
13 Proteoglycans in cancer 💬
[3] EGFR, ERBB2, ERBB4 💬 Afatinib dimaleate 💬 Afatinib [1] 285 💬
14 Proteoglycans in cancer 💬
[3] EGFR, ERBB2, ERBB4 💬 Neratinib 💬 Neratinib [1] 34 💬
15 Proteoglycans in cancer 💬
[3] EGFR, ERBB2, ERBB4 💬 Neratinib maleate 💬 Neratinib [1] 34 💬
16 Proteoglycans in cancer 💬
[3] EGFR, ERBB2, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
17 Proteoglycans in cancer 💬
[1] ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene [1] 13 💬
18 Proteoglycans in cancer 💬
[1] ESR1 💬 Clomiphene citrate 💬 Clomifene [2] 74, 77 💬
19 Proteoglycans in cancer 💬
[1] ESR1 💬 Clomifene 💬 Clomifene [2] 74, 77 💬
20 Proteoglycans in cancer 💬
[1] ESR1 💬 Danazol 💬 Danazol [5] 60, 63, 64, 65, 285 💬
21 Proteoglycans in cancer 💬
[1] ESR1 💬 Desogestrel 💬 Desogestrel [1] 230 💬
22 Proteoglycans in cancer 💬
[1] ESR1 💬 Estetrol 💬 Estetrol [1] 53 💬
23 Proteoglycans in cancer 💬
[1] ESR1 💬 Estetrol 💬 Estetrol [1] 53 💬
24 Proteoglycans in cancer 💬
[1] ESR1 💬 Estradiol 💬 Estradiol [3] 13, 76, 299 💬
25 Proteoglycans in cancer 💬
[1] ESR1 💬 Estradiol hemihydrate 💬 Estradiol [3] 13, 76, 299 💬
26 Proteoglycans in cancer 💬
[1] ESR1 💬 Estriol 💬 Estriol [2] 13, 227 💬
27 Proteoglycans in cancer 💬
[1] ESR1 💬 Estriol tripropionate 💬 Estriol [2] 13, 227 💬
28 Proteoglycans in cancer 💬
[1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
29 Proteoglycans in cancer 💬
[1] ESR1 💬 Fulvestrant 💬 Fulvestrant [1] 86 💬
30 Proteoglycans in cancer 💬
[1] ESR1 💬 Prasterone 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
31 Proteoglycans in cancer 💬
[1] ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene [2] 46, 77 💬
32 Proteoglycans in cancer 💬
[1] ESR1 💬 Raloxifene 💬 Raloxifene [2] 46, 77 💬
33 Proteoglycans in cancer 💬
[1] ESR1 💬 Tamoxifen citrate 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
34 Proteoglycans in cancer 💬
[1] ESR1 💬 Tamoxifen 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
35 Proteoglycans in cancer 💬
[1] FGFR1 💬 Infigratinib 💬 Infigratinib [1] 276 💬
36 Proteoglycans in cancer 💬
[1] FGFR1 💬 Infigratinib phosphate 💬 Infigratinib [1] 276 💬
37 Proteoglycans in cancer 💬
[2] FGFR1, KDR 💬 Catequentinib 💬 Anlotinib [1] 85 💬
38 Proteoglycans in cancer 💬
[2] FGFR1, KDR 💬 Nintedanib esylate 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
39 Proteoglycans in cancer 💬
[2] FGFR1, KDR 💬 Nintedanib 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
40 Proteoglycans in cancer 💬
[1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬
41 Proteoglycans in cancer 💬
[1] IGF1R 💬 Mecasermin 💬 Mecasermin [4] 96, 168, 265, 299 💬
42 Proteoglycans in cancer 💬
[1] IGF1R 💬 Mecasermin rinfabate 💬 Mecasermin [4] 96, 168, 265, 299 💬
43 Proteoglycans in cancer 💬
[1] IL12B 💬 Ustekinumab 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
44 Proteoglycans in cancer 💬
[2] ITGA5, ITGB1 💬 Bexotegrast 💬 Bexotegrast [1] 94 💬
45 Proteoglycans in cancer 💬
[1] ITGB1 💬 Carotegrast methyl 💬 Carotegrast methyl [1] 97 💬
46 Proteoglycans in cancer 💬
[1] KDR 💬 Axitinib 💬 Axitinib [1] 34 💬
47 Proteoglycans in cancer 💬
[1] KDR 💬 Cediranib 💬 Cediranib [1] 34 💬
48 Proteoglycans in cancer 💬
[1] KDR 💬 Cediranib maleate 💬 Cediranib [1] 34 💬
49 Proteoglycans in cancer 💬
[1] KDR 💬 Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
50 Proteoglycans in cancer 💬
[1] KDR 💬 Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
51 Proteoglycans in cancer 💬
[1] KDR 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
52 Proteoglycans in cancer 💬
[2] KDR, MET 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
53 Proteoglycans in cancer 💬
[2] KDR, MET 💬 Cabozantinib s-malate 💬 Cabozantinib [1] 34 💬
54 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
55 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
56 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib [1] 280 💬
57 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [4] 34, 278, 279, 280 💬
58 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
59 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib [1] 34 💬
60 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
61 Proteoglycans in cancer 💬
[2] MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib [6]  2 , 34, 58, 195, 279, 280 💬
62 Proteoglycans in cancer 💬
[1] MMP9 💬 Andecaliximab 💬 Andecaliximab [5] 46, 96, 97, 272, 299 💬
63 Proteoglycans in cancer 💬
[1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
64 Proteoglycans in cancer 💬
[1] MTOR 💬 Sirolimus 💬 Sirolimus [46]  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
65 Proteoglycans in cancer 💬
[1] MTOR 💬 Temsirolimus 💬 Temsirolimus [4] 13, 34, 89, 331 💬
66 Proteoglycans in cancer 💬
[4] P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬
67 Proteoglycans in cancer 💬
[4] P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬
68 Proteoglycans in cancer 💬
[1] PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib [4] 138, 278, 279, 280 💬
69 Proteoglycans in cancer 💬
[1] PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib [2] 53, 65 💬
70 Proteoglycans in cancer 💬
[1] PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
71 Proteoglycans in cancer 💬
[2] PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib [1] 121 💬
72 Proteoglycans in cancer 💬
[3] PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
73 Proteoglycans in cancer 💬
[1] PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin [1] 168 💬
74 Proteoglycans in cancer 💬
[1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬
75 Proteoglycans in cancer 💬
[2] ROCK1, ROCK2 💬 Fasudil hydrochloride 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
76 Proteoglycans in cancer 💬
[2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [5]  2 ,  5 ,  6 ,  7 , 51 💬
77 Proteoglycans in cancer 💬
[1] ROCK2 💬 Belumosudil 💬 Belumosudil [3] 51, 85, 228 💬
78 Proteoglycans in cancer 💬
[1] ROCK2 💬 Belumosudil mesylate 💬 Belumosudil [3] 51, 85, 228 💬
79 Proteoglycans in cancer 💬
[1] SMO 💬 Taladegib 💬 Taladegib [1] 85 💬
80 Proteoglycans in cancer 💬
[1] SMO 💬 Vismodegib 💬 Vismodegib [1] 85 💬
81 Proteoglycans in cancer 💬
[1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
82 Proteoglycans in cancer 💬
[1] SRC 💬 Bosutinib hydrate 💬 Bosutinib [2]  2 , 67 💬
83 Proteoglycans in cancer 💬
[1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
84 Proteoglycans in cancer 💬
[1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
85 Proteoglycans in cancer 💬
[1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
86 Proteoglycans in cancer 💬
[2] TGFB1, TGFB2 💬 Fresolimumab 💬 Fresolimumab [4] 51, 85, 222, 274 💬
87 Proteoglycans in cancer 💬
[1] TNF 💬 Adalimumab 💬 Adalimumab [21] 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
88 Proteoglycans in cancer 💬
[1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [7] 37, 46, 49, 96, 107, 226, 271 💬
89 Proteoglycans in cancer 💬
[1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
90 Proteoglycans in cancer 💬
[1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
91 Proteoglycans in cancer 💬
[1] TNF 💬 Infliximab 💬 Infliximab [25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
92 Proteoglycans in cancer 💬
[1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
93 Proteoglycans in cancer 💬
[1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬
94 Proteoglycans in cancer 💬
[1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬
95 Proteoglycans in cancer 💬
[1] TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
96 Proteoglycans in cancer 💬
[1] TNF 💬 Pomalidomide 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
97 Proteoglycans in cancer 💬
[1] TNF 💬 Thalidomide 💬 Thalidomide [21]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
98 Proteoglycans in cancer 💬
[1] VEGFA 💬 Aflibercept 💬 Aflibercept [2] 90, 166 💬
99 Proteoglycans in cancer 💬
[1] VEGFA 💬 Bevacizumab 💬 Bevacizumab [8] 13, 34, 85, 87, 89, 227, 280, 331 💬
100 Proteoglycans in cancer 💬
[1] VEGFA 💬 Ranibizumab 💬 Ranibizumab [4] 34, 166, 227, 301 💬