210. 単心室症 Disease details / Clinical trials / Drug dev / DR info

Acetylsalicylic acid
   Janssen-Cilag International N.V
      2017   Phase 3   EUCTR2015-002610-76-NL   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-ES   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-BE   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2015-002610-76-FR   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
ACT-064992
   Actelion Pharmaceuticals Ltd
      2020   Phase 3   EUCTR2018-002821-45-CZ   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002821-45-FR   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002821-45-DK   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2017   Phase 3   EUCTR2016-003320-23-GB   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2017   Phase 3   EUCTR2016-003320-23-DK   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2017   Phase 3   EUCTR2016-003320-23-DE   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2018-002821-45-PL   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2018-002821-45-GB   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2018-002821-45-DE   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2016-003320-23-PL   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
Administration OF AN ACE-inhibitor or NOT
   University Hospital, Ghent
      2002   Phase 2   NCT00263406   Belgium
Aesculus hippocastanum / horse chestnut
   Casa Espirita Terra de Ismael
      2017   Phase 2   NCT04035317   Brazil
Ambrisentan
   Kevin Hill
      2015   Phase 2   NCT02080637   United States
   Washington University School of Medicine
      2012   Phase 4   NCT01971580   United States
Aspirin
   Janssen-Cilag International N.V
      2017   Phase 3   EUCTR2015-002610-76-NL   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-ES   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-BE   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2015-002610-76-FR   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
Autologous tissue-engineered vascular graft
   University of Zurich
      2011   Phase 1;Phase 2   EUCTR2011-001187-21-DE   Germany
BAY 59-7939
   Janssen-Cilag International N.V
      2017   Phase 3   EUCTR2015-002610-76-NL   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-ES   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-BE   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2015-002610-76-FR   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
Bosentan
   Rigshospitalet, Denmark
      2011   Phase 2   NCT01292551   Denmark;Sweden
   Shanghai Jiao Tong University School of Medicine
      2010   Phase 2   NCT01662037   China
   University Hospital Birmingham
      2008   Phase 4   EUCTR2005-005898-29-GB   United Kingdom
   University of California, Los Angeles
      2010   -   NCT00989911   United States
Cardiac progenitor cell infusion
   Okayama University
      2013   Phase 2   NCT01829750   Japan
Carvedilol
   University of Texas Southwestern Medical Center
      2016   Phase 4   NCT02946892   United States
Colchicine
   University of Michigan
      2018   Phase 2/Phase 3   NCT03575572   United States
Dapagliflozin tablet
   Mayo Clinic
      2025   Phase 2   NCT06762964   United States
Digoxin
   Christoph P Hornik, MD MPH
      2019   -   NCT03877965   United States
Enalapril
   National Heart, Lung, and Blood Institute (NHLBI)
      2003   Phase 3   NCT00113087   Canada;United States
Eplerenone
   Washington University School of Medicine
      2013   Phase 4   NCT01971593   United States
Human milk derived fortifier
   The University of Texas Health Science Center at San Antonio
      2016   -   NCT02860702   United States
Human/bovine milk
   The University of Texas Health Science Center at San Antonio
      2016   -   NCT02860702   United States
IPSC-CL
   HeartWorks, Inc.
      2023   Phase 1   NCT05647213   United States
JNJ-39039039
   Janssen-Cilag International N.V
      2017   Phase 3   EUCTR2015-002610-76-NL   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-ES   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-BE   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2015-002610-76-FR   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
Liothyronine I 131
   FDA Office of Orphan Products Development
      1994   Phase 1   NCT00004828   -
Macitentan
   Actelion Pharmaceuticals Ltd
      2020   Phase 3   EUCTR2018-002821-45-CZ   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002821-45-FR   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2019   Phase 3   EUCTR2018-002821-45-DK   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2017   Phase 3   EUCTR2016-003320-23-GB   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2017   Phase 3   EUCTR2016-003320-23-DK   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      2017   Phase 3   EUCTR2016-003320-23-DE   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2018-002821-45-PL   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2018-002821-45-GB   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2018-002821-45-DE   Australia;China;Czech Republic;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
      -   Phase 3   EUCTR2016-003320-23-PL   Australia;China;Czech Republic;Czechia;Denmark;France;Germany;Ireland;New Zealand;Poland;Taiwan;United Kingdom;United States
MPC
   Boston Children's Hospital
      2017   Phase 1/Phase 2   NCT03079401   United States
MZ101
   Mezzion Pharma Co. Ltd
      2018   -   NCT03430583   Canada;United States
Nitric oxide
   Jewish General Hospital
      2020   -   NCT04292483   Canada
Normal saline
   Wake Forest University Health Sciences
      2016   Phase 2/Phase 3   NCT02975999   United States
Odsh AT 0.125 MG/KG/H
   Chimerix
      2010   Phase 1   NCT01161641   United States
Odsh AT 0.250 MG/KG/H
   Chimerix
      2010   Phase 1   NCT01161641   United States
Odsh AT 0.375 MG/KG/H
   Chimerix
      2010   Phase 1   NCT01161641   United States
PK/PD model based dosing OF digoxin IN infants with single ventricle heart disease
   Duke University
      2024   Phase 1/Phase 2   NCT06613477   United States
Pravastatin
   Children's Mercy Hospital Kansas City
      2024   Phase 1   NCT06324396   United States
Rexlemestrocel-L
   Boston Children's Hospital
      2017   Phase 1/Phase 2   NCT03079401   United States
Rivaroxaban
   Janssen-Cilag International N.V
      2017   Phase 3   EUCTR2015-002610-76-NL   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-ES   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-BE   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2015-002610-76-FR   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
Sacubitril
   University Hospital, Grenoble
      2021   -   NCT06149806   France
SCRM001_tevg
   University of Zurich
      2011   Phase 1;Phase 2   EUCTR2011-001187-21-DE   Germany
SGLT2 inhibitors
   Leiden University Medical Center
      2023   -   NCT06932081   Macedonia, The Former Yugoslav Republic of;Netherlands;United Kingdom;United States
Sildenafil
   Children's Mercy Hospital Kansas City
      2024   Phase 1   NCT06324396   United States
   Tokyo Women's Medical University
      2011   -   JPRN-UMIN000005343   Japan
   University Hospital, Montpellier
      2023   Phase 3   NCT03997097   -
Sildenafil BY injection
   Duke University
      2011   Phase 1   NCT01169519   United States
Spironolactone
   Children's Hospital of Philadelphia
      2021   Phase 1/Phase 2   NCT04901975   United States
   Emory University
      2004   -   NCT00211081   United States
Sugar pill
   University of Utah
      2011   Phase 1   NCT01291069   United States
Tadalafil citrate
   University of Utah
      2011   Phase 1   NCT01291069   United States
Tracleer
   Lars Søndergaard
      2010   -   EUCTR2010-022389-28-DK   Denmark
   University Hospital Birmingham
      2008   Phase 4   EUCTR2005-005898-29-GB   United Kingdom
Treprostinil
   Stanford University
      2015   -   NCT02498444   United States
Udenafil
   Mezzion Pharma Co. Ltd
      2023   Phase 3   NCT05918211   Korea, Republic of;United States
      2017   Phase 3   NCT03013751   Canada;Korea, Republic of;United States
      2016   Phase 3   NCT02741115   Canada;Korea, Republic of;United States
      2014   Phase 1/Phase 2   NCT02201342   Canada;United States
Valsartan
   University Hospital, Grenoble
      2021   -   NCT06149806   France
Vasopressin
   Wake Forest University Health Sciences
      2016   Phase 2/Phase 3   NCT02975999   United States
Vasopressin, arginine
   Medical College of Wisconsin
      2017   Phase 2/Phase 3   NCT03088345   United States
Vitamin C
   University of Michigan
      2009   -   NCT00974025   United States
Xarelto
   Janssen-Cilag International N.V
      2017   Phase 3   EUCTR2015-002610-76-NL   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-ES   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      2016   Phase 3   EUCTR2015-002610-76-BE   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2015-002610-76-FR   Argentina;Australia;Belgium;Brazil;Canada;China;France;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Spain;Thailand;United Kingdom;United States