Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acetylsalicylic acid1件: Acetylsalicylic acid1件: Aspirin 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 51, 210 💬
2ACT-064992----5件: 51, 85, 86, 88, 210 💬
3Administration OF AN ACE-inhibitor or NOT----1件: 210 💬
4Aesculus hippocastanum / horse chestnut----1件: 210 💬
5Ambrisentan1件: Ambrisentan1件: Ambrisentan 💬 1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 51, 66, 84, 85, 86, 88, 210, 211 💬
6Aspirin1件: Acetylsalicylic acid1件: Aspirin 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬12件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 210, 231, 271 💬
7Autologous tissue-engineered vascular graft----1件: 210 💬
8BAY 59-7939----1件: 210 💬
9Bosentan1件: Bosentan2件: Bosentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
10Cardiac progenitor cell infusion----2件: 210, 211 💬
11Carvedilol1件: Carvedilol2件: Carvedilol ,
Carvedilol phosphate 💬 		5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬 		15件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 46, 57, 86, 113, 210 💬
12Colchicine1件: Colchicine1件: Colchicine 💬 9件: TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB 💬 		11件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬8件: 42, 46, 50, 56, 93, 97, 210, 266 💬
13Dapagliflozin tablet1件: Dapagliflozin1件: Dapagliflozin 💬 --1件: 210 💬
14Digoxin1件: Digoxin1件: Digoxin 💬 4件: ATP1A,
ATP1A,
ATP1A,
ATP1A 💬 		19件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cytoskeleton in muscle cells, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 8, 46, 210 💬
15Enalapril1件: Enalapril2件: Enalapril maleate ,
Enalapril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬6件: 13, 66, 113, 210, 222, 279 💬
16Eplerenone1件: Eplerenone1件: Eplerenone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬4件: 75, 113, 210, 215 💬
17Human milk derived fortifier----1件: 210 💬
18Human/bovine milk----1件: 210 💬
19IPSC-CL----1件: 210 💬
20JNJ-39039039----1件: 210 💬
21Liothyronine I 1312件: Liothyronine,
Liothyronine I-131		3件: Liothyronine sodium ,
Liothyronine I 131 ,
Liothyronine 💬 		2件: THRA,
THRB 💬 		3件: Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬2件: 210, 212 💬
22Macitentan1件: Macitentan1件: Macitentan 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 51, 85, 86, 88, 210 💬
23MPC----2件: 210, 211 💬
24MZ101----1件: 210 💬
25Nitric oxide1件: Nitric Oxide1件: Nitric oxide 💬 --8件: 51, 85, 86, 88, 97, 210, 294, 299 💬
26Normal saline----20件: 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 97, 210, 211, 222, 226, 276, 280, 296, 299 💬
27Odsh AT 0.125 MG/KG/H----1件: 210 💬
28Odsh AT 0.250 MG/KG/H----1件: 210 💬
29Odsh AT 0.375 MG/KG/H----1件: 210 💬
30PK/PD model based dosing OF digoxin IN infants with single ventricle heart disease----1件: 210 💬
31Pravastatin1件: Pravastatin2件: Pravastatin sodium ,
Pravastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬10件: 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬
32Rexlemestrocel-L1件: Rexlemestrocel-L---2件: 210, 211 💬
33Rivaroxaban1件: Rivaroxaban1件: Rivaroxaban 💬 1件: F10 💬 1件: Complement and coagulation cascades 💬5件: 46, 49, 91, 210, 271 💬
34Sacubitril1件: Sacubitril1件: Sacubitril 💬 1件: MME 💬 4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬2件: 210, 222 💬
35SCRM001_tevg----1件: 210 💬
36SGLT2 inhibitors----2件: 210, 215 💬
37Sildenafil1件: Sildenafil2件: Sildenafil citrate ,
Sildenafil 💬 		1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
38Sildenafil BY injection1件: Sildenafil2件: Sildenafil citrate ,
Sildenafil 💬 		1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬1件: 210 💬
39Spironolactone1件: Spironolactone1件: Spironolactone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬7件: 46, 58, 67, 86, 113, 210, 225 💬
40Sugar pill----9件: 5, 6, 49, 67, 70, 86, 90, 206, 210 💬
41Tadalafil citrate1件: Tadalafil1件: Tadalafil 💬 1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬1件: 210 💬
42Tracleer1件: Bosentan2件: Bosentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 13, 51, 84, 85, 86, 88, 210, 211 💬
43Treprostinil1件: Treprostinil3件: Treprostinil ,
Treprostinil monosodium salt ,
Treprostinil diolamine 💬 		1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬3件: 85, 86, 210 💬
44Udenafil1件: Udenafil1件: Udenafil 💬 1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬2件: 86, 210 💬
45Valsartan1件: Valsartan1件: Valsartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 210, 222, 224 💬
46Vasopressin1件: Vasopressin1件: Vasopressin 💬 3件: AVPR1A,
AVPR1B,
AVPR2 💬 		6件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬2件: 210, 225 💬
47Vasopressin, arginine1件: Vasopressin1件: Vasopressin 💬 3件: AVPR1A,
AVPR1B,
AVPR2 💬 		6件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 210 💬
48Vitamin C1件: Ascorbic acid1件: Ascorbic acid 💬 --6件: 10, 192, 206, 210, 211, 212 💬
49Xarelto1件: Rivaroxaban1件: Rivaroxaban 💬 1件: F10 💬 1件: Complement and coagulation cascades 💬1件: 210 💬