1. Spinal and bulbar muscular atrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 18 / Drugs : 15 - (DrugBank : 8) / Drug target genes : 10 - Drug target pathways : 17
Spinal and bulbar muscular atrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
1 | Spinal and bulbar muscular atrophy | - |
2 | Amyotrophic lateral sclerosis | 10.000 |
46 | Malignant rheumatoid arthritis | 6.469 |
113 | Muscular dystrophy | 5.149 |
86 | Pulmonary arterial hypertension | 5.047 |
96 | Crohn disease | 4.987 |
6 | Parkinson disease | 4.978 |
13 | Multiple sclerosis/Neuromyelitis optica | 4.955 |
256 | Muscle glycogenosis | 4.065 |
231 | Alpha-1-antitrypsin deficiency | 4.011 |
168 | Ehlers-Danlos syndrome | 3.889 |
53 | Sjogren syndrome | 3.862 |
70 | Spinal stenosis | 3.818 |
51 | Scleroderma | 3.727 |
10 | Charcot-Marie-Tooth disease | 3.636 |
38 | Stevens-Johnson syndrome | 3.333 |
114 | Non-dystrophic myotonia syndrome | 3.194 |
127 | Frontotemporal lobar degeneration | 2.812 |
58 | Hypertrophic cardiomyopathy | 2.760 |
140 | Dorabe syndrome | 2.760 |
36 | Epidermolysis bullosa | 2.755 |
144 | Lennox-Gastaut syndrome | 2.755 |
193 | Prader-Willi syndrome | 2.745 |
107 | Juvenile idiopathic arthritis | 2.740 |
298 | Hereditary pancreatitis | 2.736 |
226 | Interstitial cystitis with Hunners ulcer | 2.695 |
28 | Systemic amyloidosis | 2.689 |
156 | Rett syndrome | 2.662 |
84 | Sarcoidosis | 2.652 |
8 | Huntington disease | 2.649 |
34 | Neurofibromatosis | 2.644 |
97 | Ulcerative colitis | 2.587 |
3 | Spinal muscular atrophy | 1.019 |
111 | Congenital myopathy | 1.000 |