144. Lennox-Gastaut syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 111 / Drugs : 72 - (DrugBank : 14) / Drug target genes : 49 - Drug target pathways : 61
Lennox-Gastaut syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
144 | Lennox-Gastaut syndrome | - |
140 | Dorabe syndrome | 41.250 |
6 | Parkinson disease | 38.939 |
13 | Multiple sclerosis/Neuromyelitis optica | 36.947 |
156 | Rett syndrome | 36.470 |
97 | Ulcerative colitis | 36.225 |
2 | Amyotrophic lateral sclerosis | 35.902 |
193 | Prader-Willi syndrome | 35.826 |
8 | Huntington disease | 33.328 |
206 | Fragile X syndrome | 23.520 |
145 | West syndrome | 22.639 |
298 | Hereditary pancreatitis | 21.053 |
18 | Spinocerebellar degeneration | 20.847 |
17 | Multiple system atrophy | 18.998 |
3 | Spinal muscular atrophy | 18.531 |
5 | Progressive supranuclear palsy | 17.465 |
70 | Spinal stenosis | 17.393 |
272 | Fibrodysplasia ossificans progressiva | 17.268 |
96 | Crohn disease | 16.826 |
36 | Epidermolysis bullosa | 16.524 |
231 | Alpha-1-antitrypsin deficiency | 16.200 |
152 | PCDH19 related syndrome | 16.000 |
46 | Malignant rheumatoid arthritis | 15.511 |
155 | Acquired aphasia with convulsive disorder | 13.681 |
201 | Angelman syndrome | 13.061 |
158 | Tuberous sclerosis | 12.469 |
205 | Fragile X syndrome related disease | 12.121 |
84 | Sarcoidosis | 12.073 |
34 | Neurofibromatosis | 11.897 |
22 | Moyamoya disease | 11.382 |
98 | Eosinophilic gastrointestinal disease | 10.501 |
21 | Mitochondrial disease | 9.914 |
296 | Biliary atresia | 9.056 |
75 | Cushing disease | 8.005 |
203 | 22q11.2 deletion syndrome | 6.376 |
226 | Interstitial cystitis with Hunners ulcer | 4.638 |
149 | Hemiconvulsion hemiplegia epilepsy syndrome | 4.456 |
86 | Pulmonary arterial hypertension | 4.026 |
114 | Non-dystrophic myotonia syndrome | 3.333 |
58 | Hypertrophic cardiomyopathy | 3.031 |
168 | Ehlers-Danlos syndrome | 3.005 |
1 | Spinal and bulbar muscular atrophy | 2.755 |
51 | Scleroderma | 2.745 |
10 | Charcot-Marie-Tooth disease | 2.551 |
90 | Retinitis pigmentosa | 2.399 |
127 | Frontotemporal lobar degeneration | 2.050 |
38 | Stevens-Johnson syndrome | 2.007 |
167 | Marfan syndrome | 1.796 |
81 | Congenital adrenal hyperplasia | 1.551 |
256 | Muscle glycogenosis | 1.234 |
28 | Systemic amyloidosis | 1.213 |
202 | Smith-Magenis syndrome | 1.041 |