193. Prader-Willi syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 140 / Drugs : 137 - (DrugBank : 26) / Drug target genes : 51 - Drug target pathways : 64
Prader-Willi syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 193 | Prader-Willi syndrome | - |
| 6 | Parkinson disease | 42.594 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 42.270 |
| 140 | Dorabe syndrome | 35.982 |
| 144 | Lennox-Gastaut syndrome | 35.826 |
| 156 | Rett syndrome | 33.094 |
| 97 | Ulcerative colitis | 30.888 |
| 2 | Amyotrophic lateral sclerosis | 27.628 |
| 8 | Huntington disease | 25.929 |
| 206 | Fragile X syndrome | 23.208 |
| 17 | Multiple system atrophy | 22.437 |
| 96 | Crohn disease | 21.086 |
| 298 | Hereditary pancreatitis | 20.767 |
| 5 | Progressive supranuclear palsy | 19.572 |
| 3 | Spinal muscular atrophy | 19.507 |
| 70 | Spinal stenosis | 19.492 |
| 18 | Spinocerebellar degeneration | 19.336 |
| 36 | Epidermolysis bullosa | 17.517 |
| 46 | Malignant rheumatoid arthritis | 17.284 |
| 272 | Fibrodysplasia ossificans progressiva | 17.195 |
| 231 | Alpha-1-antitrypsin deficiency | 16.059 |
| 152 | PCDH19-related syndrome | 16.000 |
| 145 | West syndrome | 15.468 |
| 84 | Sarcoidosis | 15.013 |
| 158 | Tuberous sclerosis | 14.790 |
| 22 | Moyamoya disease | 13.840 |
| 34 | Neurofibromatosis | 13.711 |
| 155 | Acquired aphasia with convulsive disorder | 13.582 |
| 205 | Fragile X syndrome related disease | 13.373 |
| 201 | Angelman syndrome | 13.005 |
| 75 | Cushing disease | 12.831 |
| 21 | Mitochondrial disease | 11.898 |
| 98 | Eosinophilic gastro-intestinal disorder | 10.366 |
| 296 | Biliary atresia | 9.948 |
| 203 | 22q11.2 deletion syndrome | 6.353 |
| 226 | Interstitial cystitis with Hunners ulcer | 6.065 |
| 168 | Ehlers-Danlos syndrome | 5.658 |
| 86 | Pulmonary arterial hypertension | 5.265 |
| 58 | Hypertrophic cardiomyopathy | 3.636 |
| 81 | Congenital adrenal hyperplasia | 3.353 |
| 113 | Muscular dystrophy | 3.323 |
| 114 | Non-dystrophic myotonia syndrome | 3.309 |
| 157 | Sturge-Weber syndrome | 3.263 |
| 127 | Frontotemporal lobar degeneration | 3.256 |
| 51 | Scleroderma | 3.212 |
| 167 | Marfan syndrome | 2.745 |
| 1 | Spinal and bulbar muscular atrophy | 2.745 |
| 10 | Charcot-Marie-Tooth disease | 2.540 |
| 67 | Polycystic kidney disease | 2.073 |
| 38 | Stevens-Johnson syndrome | 1.993 |
| 90 | Retinitis pigmentosa | 1.824 |
| 107 | Juvenile idiopathic arthritis | 1.774 |
| 256 | Muscle glycogenosis | 1.731 |
| 28 | Systemic amyloidosis | 1.601 |
| 78 | Hypopituitarism | 1.428 |
| 50 | Dermatomyositis | 1.368 |
| 72 | Pituitary ADH secretion disorder | 1.039 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
| 191 | Werner syndrome | 1.000 |