20. Adrenoleukodystrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 61 / Drugs : 90 - (DrugBank : 31) / Drug target genes : 23 - Drug target pathways : 126
Adrenoleukodystrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 20 | Adrenoleukodystrophy | - |
| 19 | Lysosomal storage disease | 11.265 |
| 46 | Malignant rheumatoid arthritis | 10.614 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 10.542 |
| 49 | Systemic lupus erythematosus | 9.534 |
| 96 | Crohn disease | 9.333 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 9.177 |
| 164 | Oculocutaneous albinism | 8.471 |
| 65 | Primary immunodeficiency | 8.450 |
| 284 | Diamond-Blackfan anemia | 8.250 |
| 60 | Aplastic anemia | 8.104 |
| 299 | Cystic fibrosis | 7.227 |
| 51 | Scleroderma | 7.125 |
| 2 | Amyotrophic lateral sclerosis | 6.926 |
| 326 | Osteopetrosis | 6.673 |
| 285 | Fanconi anemia | 6.364 |
| 283 | Acquired pure red cell aplasia | 6.341 |
| 95 | Autoimmune hepatitis | 6.201 |
| 85 | Idiopathic interstitial pneumonia | 6.111 |
| 93 | Primary biliary cholangitis | 6.104 |
| 151 | Rasmussen encephalitis | 6.000 |
| 6 | Parkinson disease | 5.822 |
| 40 | Takayasu arteritis | 5.596 |
| 222 | Primary nephrotic syndrome | 5.440 |
| 28 | Systemic amyloidosis | 5.372 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 5.172 |
| 162 | Pemphigoid | 5.132 |
| 228 | Bronchiolitis obliterans | 5.132 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 97 | Ulcerative colitis | 4.927 |
| 286 | Hereditary sideroblastic anemia | 4.909 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 4.848 |
| 36 | Epidermolysis bullosa | 4.659 |
| 53 | Sjogren syndrome | 4.552 |
| 61 | Autoimmune hemolytic anemia | 4.538 |
| 42 | Polyarteritis nodosa | 4.476 |
| 224 | Purpura nephritis | 4.455 |
| 160 | Congenital ichthyosis | 4.083 |
| 66 | IgA nephropathy | 4.073 |
| 39 | Toxic epidermal necrolysis | 4.017 |
| 94 | Primary sclerosing cholangitis | 3.986 |
| 55 | Relapsing polychondritis | 3.818 |
| 11 | Myasthenia gravis | 3.814 |
| 90 | Retinitis pigmentosa | 3.740 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.545 |
| 38 | Stevens-Johnson syndrome | 3.382 |
| 269 | Pyogenic arthritis | 3.382 |
| 41 | Giant cell arteritis | 3.240 |
| 56 | Behcet disease | 3.155 |
| 50 | Dermatomyositis | 2.923 |
| 107 | Juvenile idiopathic arthritis | 2.870 |
| 227 | Osler disease | 2.775 |
| 274 | Osteogenesis Imperfecta | 2.516 |
| 158 | Tuberous sclerosis | 2.384 |
| 309 | Progressive myoclonus epilepsy | 2.352 |
| 64 | Thrombotic thrombocytopenic purpura | 2.344 |
| 26 | HTLV-1-associated myelopathy | 2.325 |
| 58 | Hypertrophic cardiomyopathy | 2.182 |
| 113 | Muscular dystrophy | 2.080 |
| 63 | Idiopathic thrombocytopenic purpura | 1.566 |
| 84 | Sarcoidosis | 1.372 |
| 8 | Huntington disease | 1.366 |
| 86 | Pulmonary arterial hypertension | 1.330 |
| 7 | Corticobasal degeneration | 1.273 |
| 324 | Methylglutaconic aciduria | 1.000 |