225. Congenital nephrogenic diabetes insipidus Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 15 / Drugs : 48 - (DrugBank : 18) / Drug target genes : 31 - Drug target pathways : 65
Congenital nephrogenic diabetes insipidus and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
225 | Congenital nephrogenic diabetes insipidus | - |
86 | Pulmonary arterial hypertension | 23.435 |
13 | Multiple sclerosis/Neuromyelitis optica | 19.633 |
115 | Hereditary periodic paralysis | 13.000 |
154 | Epilepsy with continuous spikes and waves during slow sleep | 13.000 |
114 | Non-dystrophic myotonia syndrome | 10.954 |
230 | Alveolar hypoventilation syndrome | 10.954 |
155 | Acquired aphasia with convulsive disorder | 8.936 |
299 | Cystic fibrosis | 8.672 |
90 | Retinitis pigmentosa | 8.667 |
6 | Parkinson disease | 6.143 |
97 | Ulcerative colitis | 3.800 |
67 | Polycystic kidney disease | 3.368 |
51 | Scleroderma | 3.202 |
113 | Muscular dystrophy | 2.929 |
58 | Hypertrophic cardiomyopathy | 2.416 |
46 | Malignant rheumatoid arthritis | 2.387 |
337 | Homocystinuria | 2.000 |
282 | Congenital dyserythropoietic anemia | 2.000 |
77 | Growth hormone secreting pituitary adenoma | 2.000 |
294 | Congenital diaphragmatic hernia | 1.920 |
222 | Primary nephrotic syndrome | 1.672 |
75 | Cushing disease | 1.665 |
88 | Chronic thromboembolic pulmonary hypertension | 1.600 |
65 | Primary immunodeficiency | 1.520 |
210 | Single Ventricle | 1.484 |
49 | Systemic lupus erythematosus | 1.453 |
158 | Tuberous sclerosis | 1.429 |
96 | Crohn disease | 1.371 |
2 | Amyotrophic lateral sclerosis | 1.367 |
271 | Ankylosing spondylitis | 1.341 |
21 | Mitochondrial disease | 1.277 |
298 | Hereditary pancreatitis | 1.226 |
206 | Fragile X syndrome | 1.219 |
301 | Macular dystrophy | 1.200 |
84 | Sarcoidosis | 1.087 |
251 | Urea cycle disorder | 1.067 |
72 | Pituitary ADH secretion disorder | 1.067 |
71 | Idiopathic osteonecrosis of the femoral head | 1.067 |
265 | Lipodystrophy | 1.067 |