225. Congenital nephrogenic diabetes insipidus Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 19 / Drugs : 56 - (DrugBank : 21) / Drug target genes : 33 - Drug target pathways : 67
Congenital nephrogenic diabetes insipidus and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 225 | Congenital nephrogenic diabetes insipidus | - |
| 86 | Pulmonary arterial hypertension | 23.435 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 19.633 |
| 115 | Hereditary periodic paralysis | 13.000 |
| 154 | Epilepsy with continuous spikes and waves during slow sleep | 13.000 |
| 114 | Non-dystrophic myotonia syndrome | 10.954 |
| 230 | Alveolar hypoventilation syndrome | 10.954 |
| 155 | Acquired aphasia with convulsive disorder | 8.936 |
| 299 | Cystic fibrosis | 8.672 |
| 90 | Retinitis pigmentosa | 8.667 |
| 6 | Parkinson disease | 6.143 |
| 97 | Ulcerative colitis | 3.800 |
| 67 | Polycystic kidney disease | 3.368 |
| 51 | Scleroderma | 3.202 |
| 113 | Muscular dystrophy | 2.929 |
| 58 | Hypertrophic cardiomyopathy | 2.416 |
| 46 | Malignant rheumatoid arthritis | 2.387 |
| 337 | Homocystinuria | 2.000 |
| 282 | Congenital dyserythropoietic anemia | 2.000 |
| 77 | Growth hormone secreting pituitary adenoma | 2.000 |
| 294 | Congenital diaphragmatic hernia | 1.920 |
| 222 | Primary nephrotic syndrome | 1.672 |
| 75 | Cushing disease | 1.665 |
| 88 | Chronic thromboembolic pulmonary hypertension | 1.600 |
| 65 | Primary immunodeficiency | 1.520 |
| 210 | Single Ventricle | 1.484 |
| 49 | Systemic lupus erythematosus | 1.453 |
| 158 | Tuberous sclerosis | 1.429 |
| 96 | Crohn disease | 1.371 |
| 2 | Amyotrophic lateral sclerosis | 1.367 |
| 271 | Ankylosing spondylitis | 1.341 |
| 21 | Mitochondrial disease | 1.277 |
| 298 | Hereditary pancreatitis | 1.226 |
| 206 | Fragile X syndrome | 1.219 |
| 301 | Macular dystrophy | 1.200 |
| 84 | Sarcoidosis | 1.087 |
| 251 | Urea cycle disorder | 1.067 |
| 72 | Pituitary ADH secretion disorder | 1.067 |
| 71 | Idiopathic osteonecrosis of the femoral head | 1.067 |
| 265 | Lipodystrophy | 1.067 |