288. Autoimmune acquired coagulation factor deficiency Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 228 / Drugs : 168 - (DrugBank : 33) / Drug target genes : 12 - Drug target pathways : 26
Autoimmune acquired coagulation factor deficiency and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 288 | Autoimmune acquired coagulation factor deficiency | - |
| 46 | Malignant rheumatoid arthritis | 9.643 |
| 96 | Crohn disease | 7.002 |
| 6 | Parkinson disease | 6.973 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 6.095 |
| 13 | Multiple sclerosis | 5.723 |
| 11 | Myasthenia gravis | 5.400 |
| 70 | Spinal stenosis | 5.114 |
| 118 | Myelomeningocele | 5.000 |
| 169 | Menkes disease | 4.667 |
| 170 | Occipital horn syndrome | 4.667 |
| 206 | Fragile X syndrome | 3.277 |
| 113 | Muscular dystrophy | 3.230 |
| 17 | Multiple system atrophy | 3.213 |
| 86 | Pulmonary arterial hypertension | 3.022 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 2 | Amyotrophic lateral sclerosis | 2.896 |
| 22 | Moyamoya disease | 2.857 |
| 64 | Thrombotic thrombocytopenic purpura | 2.517 |
| 5 | Progressive supranuclear palsy | 2.369 |
| 8 | Huntington disease | 2.286 |
| 51 | Scleroderma | 2.212 |
| 210 | Single Ventricle | 1.953 |
| 67 | Polycystic kidney disease | 1.864 |
| 127 | Frontotemporal lobar degeneration | 1.840 |
| 271 | Ankylosing spondylitis | 1.829 |
| 107 | Juvenile idiopathic arthritis | 1.736 |
| 226 | Interstitial cystitis with Hunners ulcer | 1.671 |
| 28 | Systemic amyloidosis | 1.662 |
| 65 | Primary immunodeficiency | 1.590 |
| 215 | Tetralogy of Fallot | 1.580 |
| 299 | Cystic fibrosis | 1.577 |
| 85 | Idiopathic interstitial pneumonia | 1.571 |
| 49 | Systemic lupus erythematosus | 1.547 |
| 97 | Ulcerative colitis | 1.515 |
| 212 | Tricuspid atresia | 1.438 |
| 79 | Homozygous familial hypercholesterolemia | 1.333 |
| 57 | Idiopathic dilated cardiomyopathy | 1.333 |
| 66 | IgA nephropathy | 1.244 |
| 78 | Hypopituitarism | 1.172 |
| 63 | Idiopathic thrombocytopenic purpura | 1.165 |
| 58 | Hypertrophic cardiomyopathy | 1.148 |
| 90 | Retinitis pigmentosa | 1.143 |
| 72 | Pituitary ADH secretion disorder | 1.111 |
| 222 | Primary nephrotic syndrome | 1.093 |
| 75 | Cushing disease | 1.090 |
| 84 | Sarcoidosis | 1.041 |
| 34 | Neurofibromatosis | 1.032 |
| 317 | Trifunctional protein deficiency | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |