About Icons

Icon	Function
💬	A pop-up explanation appears when you mouse-over the text beside this icon. Also, an explanation window appears when you click this icon.
	The links beside this icon are links to external sites.
	Clicking this icon sorts the table by the item with this icon (Numerical or alphabetical order). Each click toggles between ascending and descending order.
	A text longer than 100 characters is fully displayed or collapsed.
	The contents of the displayed table are downloaded as a file named "table.csv".

Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[4] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Vasopressin-regulated water reabsorption

Desmopressin acetate 💬

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

2

[4] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Vasopressin-regulated water reabsorption

Desmopressin 💬

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

3

[6] Nicotinate and nicotinamide metabolism, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion

Daratumumab 💬

[10] 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬

Disease ID	Name
13	Multiple sclerosis
16	Crow-Fukase syndrome
28	Systemic amyloidosis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
60	Aplastic anemia
63	Idiopathic thrombocytopenic purpura
288	Autoimmune acquired coagulation factor deficiency
331	Idiopathic multicentric castleman disease

4

[1] Complement and coagulation cascades

Emicizumab 💬

[1] 288 💬

5

[1] Complement and coagulation cascades

Eptacog alfa 💬

Name	Other Names
Eptacog alfa	Eptacog alfa (INN) Eptacog alfa (activated) (genetical recombination) (JAN) Coagulation Factor VIIa Coagulation factor VIIa (recombinant)-jncw Novo- seven (TN) Sevenfact (TN) SEVENFACT

Coagulation factor VIIa Recombinant Human

[1] 288 💬

6

[1] Complement and coagulation cascades

Octocog alfa 💬

Antihemophilic factor, human recombinant

[1] 288 💬

7

[1] Complement and coagulation cascades

Desmopressin acetate 💬

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

8

[1] Complement and coagulation cascades

Susoctocog alfa 💬

Susoctocog alfa

[1] 288 💬

9

[1] Complement and coagulation cascades

Efanesoctocog alfa 💬

Efanesoctocog alfa

[1] 288 💬

10

[1] Complement and coagulation cascades

Desmopressin 💬

[6] 6, 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

11

[1] Complement and coagulation cascades

Rurioctocog alfa pegol 💬

Rurioctocog alfa pegol

[1] 288 💬

12

[1] Complement and coagulation cascades

Emicizumab 💬

[1] 288 💬

13

[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion

Simvastatin 💬

[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis
15	Inclusion body myositis
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
94	Primary sclerosing cholangitis
158	Tuberous sclerosis
160	Congenital ichthyosis
162	Pemphigoid
195	Noonan syndrome
265	Lipodystrophy
288	Autoimmune acquired coagulation factor deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis
310	Congenital anomalies syndrome

14

[3] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage

Oprelvekin 💬

[3] 96, 97, 288 💬

15

[1] Hematopoietic cell lineage

Name	Other Names
Rituximab	Rituximab (USAN/INN) Rituximab (genetical recombination) (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 1] (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 2] (JAN) Rituximab-abbs Rituximab-pvvr Rituximab-arrx Rituxan (TN) Riabni (TN) Truximab (TN) RIABNI RITUXAN RUXIENCE TRUXIMA

[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis
14	Chronic inflammatory demyelinating polyneuropathy
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
34	Neurofibromatosis
35	Pemphigus
36	Epidermolysis bullosa
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
52	Mixed connective tissue disease
53	Sjogren syndrome
55	Relapsing polychondritis
56	Behcet disease
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
83	Addison disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
96	Crohn disease
97	Ulcerative colitis
162	Pemphigoid
172	Hypophosphatasia
220	Rapidly progressive glomerulonephritis
222	Primary nephrotic syndrome
229	Autoimmune pulmonary alveolar proteinosis
256	Muscle glycogenosis
271	Ankylosing spondylitis
274	Osteogenesis Imperfecta
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
296	Biliary atresia
300	IgG4-related disease
331	Idiopathic multicentric castleman disease

16

[1] Neuroactive ligand-receptor interaction

Prednisone 💬

Name	Other Names
Prednisone	Prednisone (USP) Prednisone monohydrate Deltasone (TN) Meticorten (TN) Rayos (TN) RAYOS P- PACK PREDNISONE 20MG, 7- DAY TAPERING DOSE PACK PREDNISONE PREDNISONE TABLETS, USP, 10 MG PREDNISONE TABLETS, USP, 20 MG PREDNISONE TABLETS, USP, 5 MG

[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
11	Myasthenia gravis
13	Multiple sclerosis
14	Chronic inflammatory demyelinating polyneuropathy
18	Spinocerebellar degeneration
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
35	Pemphigus
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
81	Congenital adrenal hyperplasia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
113	Muscular dystrophy
145	West syndrome
162	Pemphigoid
164	Oculocutaneous albinism
205	Fragile X syndrome related disease
222	Primary nephrotic syndrome
224	Purpura nephritis
228	Bronchiolitis obliterans
251	Urea cycle disorder
269	Pyogenic arthritis
283	Acquired pure red cell aplasia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
299	Cystic fibrosis
300	IgG4-related disease
303	Usher syndrome
307	Canavan disease
331	Idiopathic multicentric castleman disease

17

[4] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A

Tranexamic acid 💬

Tranexamic acid

[8] 46, 65, 70, 215, 227, 274, 288, 299 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
65	Primary immunodeficiency
70	Spinal stenosis
215	Tetralogy of Fallot
227	Osler disease
274	Osteogenesis Imperfecta
288	Autoimmune acquired coagulation factor deficiency
299	Cystic fibrosis

18

[8] Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases

Bortezomib 💬

[18] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
66	IgA nephropathy
172	Hypophosphatasia
222	Primary nephrotic syndrome
228	Bronchiolitis obliterans
256	Muscle glycogenosis
283	Acquired pure red cell aplasia
288	Autoimmune acquired coagulation factor deficiency
331	Idiopathic multicentric castleman disease