90. Retinitis pigmentosa Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 186 / Drugs : 191 - (DrugBank : 52) / Drug target genes : 43 - Drug target pathways : 87
Retinitis pigmentosa and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 90 | Retinitis pigmentosa | - |
| 13 | Multiple sclerosis | 35.338 |
| 6 | Parkinson disease | 21.490 |
| 86 | Pulmonary arterial hypertension | 16.969 |
| 2 | Amyotrophic lateral sclerosis | 14.535 |
| 115 | Hereditary periodic paralysis | 13.000 |
| 154 | Epilepsy with continuous spikes and waves during slow sleep | 13.000 |
| 230 | Alveolar hypoventilation syndrome | 11.778 |
| 114 | Non-dystrophic myotonia syndrome | 10.347 |
| 225 | Congenital nephrogenic diabetes insipidus | 8.667 |
| 155 | Acquired aphasia with convulsive disorder | 7.730 |
| 26 | HTLV-1-associated myelopathy | 7.684 |
| 97 | Ulcerative colitis | 7.218 |
| 65 | Primary immunodeficiency | 7.140 |
| 102 | Rubinstein-Taybi syndrome | 7.000 |
| 299 | Cystic fibrosis | 6.218 |
| 226 | Interstitial cystitis with Hunners ulcer | 6.188 |
| 39 | Toxic epidermal necrolysis | 6.174 |
| 85 | Idiopathic interstitial pneumonia | 6.169 |
| 164 | Oculocutaneous albinism | 6.137 |
| 96 | Crohn disease | 5.521 |
| 222 | Primary nephrotic syndrome | 5.484 |
| 58 | Hypertrophic cardiomyopathy | 5.204 |
| 140 | Dorabe syndrome | 5.204 |
| 4 | Primary lateral sclerosis | 5.133 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 233 | Wolfram syndrome | 4.818 |
| 5 | Progressive supranuclear palsy | 4.612 |
| 50 | Dermatomyositis | 4.424 |
| 151 | Rasmussen encephalitis | 4.252 |
| 46 | Malignant rheumatoid arthritis | 4.120 |
| 51 | Scleroderma | 3.901 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 3.856 |
| 224 | Purpura nephritis | 3.800 |
| 331 | Idiopathic multicentric castleman disease | 3.786 |
| 20 | Adrenoleukodystrophy | 3.740 |
| 34 | Neurofibromatosis | 3.548 |
| 113 | Muscular dystrophy | 3.390 |
| 160 | Congenital ichthyosis | 3.333 |
| 283 | Acquired pure red cell aplasia | 3.333 |
| 286 | Hereditary sideroblastic anemia | 3.316 |
| 127 | Frontotemporal lobar degeneration | 3.306 |
| 49 | Systemic lupus erythematosus | 3.293 |
| 89 | Lymphangioleiomyomatosis | 3.289 |
| 11 | Myasthenia gravis | 3.122 |
| 7 | Corticobasal degeneration | 3.005 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 107 | Juvenile idiopathic arthritis | 2.925 |
| 284 | Diamond-Blackfan anemia | 2.909 |
| 53 | Sjogren syndrome | 2.855 |
| 38 | Stevens-Johnson syndrome | 2.841 |
| 269 | Pyogenic arthritis | 2.841 |
| 17 | Multiple system atrophy | 2.737 |
| 74 | Prolactin secreting pituitary adenoma | 2.709 |
| 64 | Thrombotic thrombocytopenic purpura | 2.709 |
| 70 | Spinal stenosis | 2.655 |
| 63 | Idiopathic thrombocytopenic purpura | 2.496 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 2.490 |
| 215 | Tetralogy of Fallot | 2.490 |
| 144 | Lennox-Gastaut syndrome | 2.399 |
| 95 | Autoimmune hepatitis | 2.397 |
| 81 | Congenital adrenal hyperplasia | 2.381 |
| 55 | Relapsing polychondritis | 2.381 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 2.381 |
| 256 | Muscle glycogenosis | 2.355 |
| 3 | Spinal muscular atrophy | 2.317 |
| 309 | Progressive myoclonus epilepsy | 2.296 |
| 66 | IgA nephropathy | 2.200 |
| 201 | Angelman syndrome | 2.171 |
| 212 | Tricuspid atresia | 2.163 |
| 274 | Osteogenesis Imperfecta | 2.114 |
| 227 | Osler disease | 2.108 |
| 40 | Takayasu arteritis | 1.998 |
| 61 | Autoimmune hemolytic anemia | 1.998 |
| 42 | Polyarteritis nodosa | 1.950 |
| 8 | Huntington disease | 1.944 |
| 326 | Osteopetrosis | 1.913 |
| 166 | Pseudoxanthoma elasticum | 1.873 |
| 36 | Epidermolysis bullosa | 1.857 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 1.831 |
| 193 | Prader-Willi syndrome | 1.824 |
| 167 | Marfan syndrome | 1.796 |
| 285 | Fanconi anemia | 1.788 |
| 41 | Giant cell arteritis | 1.692 |
| 162 | Pemphigoid | 1.692 |
| 228 | Bronchiolitis obliterans | 1.692 |
| 93 | Primary biliary cholangitis | 1.637 |
| 158 | Tuberous sclerosis | 1.637 |
| 56 | Behcet disease | 1.612 |
| 156 | Rett syndrome | 1.545 |
| 60 | Aplastic anemia | 1.487 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 1.376 |
| 118 | Myelomeningocele | 1.240 |
| 28 | Systemic amyloidosis | 1.213 |
| 19 | Lysosomal storage disease | 1.193 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.143 |
| 169 | Menkes disease | 1.122 |
| 170 | Occipital horn syndrome | 1.122 |
| 254 | Porphyria | 1.100 |
| 37 | Generalised pustular psoriasis | 1.061 |
| 202 | Smith-Magenis syndrome | 1.041 |
| 78 | Hypopituitarism | 1.020 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |