Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ABAT 💬 [6] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Valproic acid 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
2 ABAT 💬 [6] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Valproate sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
3 ABAT 💬 [6] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Divalproex sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
4 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine tartrate 💬 Brimonidine [2] 13, 90 💬
5 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine 💬 Brimonidine [2] 13, 90 💬
6 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine tartrate 💬 Brimonidine [2] 13, 90 💬
7 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine 💬 Brimonidine [2] 13, 90 💬
8 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine tartrate 💬 Brimonidine [2] 13, 90 💬
9 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine 💬 Brimonidine [2] 13, 90 💬
10 ALDH1B1 💬 [13] Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, Valine, leucine and isoleucine degradation, Lysine degradation, Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, beta-Alanine metabolism, Glycerolipid metabolism, Pyruvate metabolism, Pantothenate and CoA biosynthesis, Alcoholic liver disease Disulfiram 💬 Disulfiram [3] 46, 90, 301 💬
11 ALDH2 💬 [13] Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, Valine, leucine and isoleucine degradation, Lysine degradation, Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, beta-Alanine metabolism, Glycerolipid metabolism, Pyruvate metabolism, Pantothenate and CoA biosynthesis, Alcoholic liver disease Disulfiram 💬 Disulfiram [3] 46, 90, 301 💬
12 ALDH3A2 💬 [13] Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, Valine, leucine and isoleucine degradation, Lysine degradation, Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, beta-Alanine metabolism, Glycerolipid metabolism, Pyruvate metabolism, Pantothenate and CoA biosynthesis, Alcoholic liver disease Disulfiram 💬 Disulfiram [3] 46, 90, 301 💬
13 ALDH5A1 💬 [2] Alanine, aspartate and glutamate metabolism, Butanoate metabolism Valproate sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
14 ALDH5A1 💬 [2] Alanine, aspartate and glutamate metabolism, Butanoate metabolism Valproic acid 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
15 ALDH5A1 💬 [2] Alanine, aspartate and glutamate metabolism, Butanoate metabolism Divalproex sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
16 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
17 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
18 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
19 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
20 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
21 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
22 CA1 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
23 CA1 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
24 CA1 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
25 CA1 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
26 CA12 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
27 CA12 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
28 CA12 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
29 CA12 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
30 CA13 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
31 CA13 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
32 CA13 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
33 CA13 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
34 CA14 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
35 CA14 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
36 CA14 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
37 CA14 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
38 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
39 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
40 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
41 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide 💬 Dorzolamide [1] 90 💬
42 CA3 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
43 CA3 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
44 CA3 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
45 CA3 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
46 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
47 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Dorzolamide 💬 Dorzolamide [1] 90 💬
48 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
49 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
50 CA5A 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
51 CA5A 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
52 CA5A 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
53 CA5A 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
54 CA5B 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
55 CA5B 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
56 CA5B 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
57 CA5B 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
58 CA6 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
59 CA6 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
60 CA6 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
61 CA6 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
62 CA7 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
63 CA7 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
64 CA7 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
65 CA7 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
66 CA8 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
67 CA8 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
68 CA8 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
69 CA8 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
70 CA9 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
71 CA9 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
72 CA9 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
73 CA9 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [8] 13, 67, 90, 115, 155, 222, 225, 230 💬
74 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
75 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
76 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
77 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Valproate sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
78 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Valproic acid 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
79 CACNA1G 💬 [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Divalproex sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
80 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
81 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproate sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
82 CACNA1H 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Divalproex sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
83 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
84 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproate sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
85 CACNA1I 💬 [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Divalproex sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
86 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
87 DDC 💬 [8] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Carbidopa 💬 Carbidopa [7] 6, 13, 17, 90, 140, 164, 201 💬
88 DRD1 💬 [12] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Levodopa 💬 Levodopa [8] 5, 6, 17, 90, 120, 140, 164, 201 💬
89 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Levodopa 💬 Levodopa [8] 5, 6, 17, 90, 120, 140, 164, 201 💬
90 DRD3 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa [8] 5, 6, 17, 90, 120, 140, 164, 201 💬
91 DRD4 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa [8] 5, 6, 17, 90, 120, 140, 164, 201 💬
92 DRD5 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa [8] 5, 6, 17, 90, 120, 140, 164, 201 💬
93 GAD1 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Divalproex sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
94 GAD1 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
95 GAD1 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproate sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
96 GAD2 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Divalproex sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
97 GAD2 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
98 GAD2 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproate sodium 💬 Valproic acid [11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
99 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin magnesium 💬 Pitavastatin [4] 49, 71, 79, 90 💬
100 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin calcium 💬 Pitavastatin [4] 49, 71, 79, 90 💬
101 MTNR1A 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
102 MTNR1B 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
103 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
104 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone hexacetonide 💬 Triamcinolone [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
105 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone sodium phosphate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
106 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone acetate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
107 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone sodium phosphate 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
108 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Fluocinolone acetonide 💬 Fluocinolone acetonide [1] 90 💬
109 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone 💬 Triamcinolone [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
110 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone phosphate 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
111 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone benzoate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
112 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone acetonide 💬 Triamcinolone [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
113 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
114 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone [58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
115 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone diacetate 💬 Triamcinolone [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
116 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone dipropionate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
117 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone valerate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
118 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Sildenafil 💬 Sildenafil [17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
119 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Sildenafil citrate 💬 Sildenafil [17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
120 PGF 💬 [7] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Integrin signaling, Pathways in cancer Aflibercept 💬 Aflibercept [2] 90, 166 💬
121 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
122 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
123 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
124 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
125 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
126 PTGFR 💬 [3] Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction Unoprostone 💬 Unoprostone [1] 90 💬
127 PTGFR 💬 [3] Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction Isopropyl unoprostone 💬 Unoprostone [1] 90 💬
128 RARA 💬 [5] Th17 cell differentiation, Estrogen signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Vitamin A 💬 Vitamin A [4] 13, 53, 90, 97 💬
129 RARB 💬 [4] Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer Vitamin A 💬 Vitamin A [4] 13, 53, 90, 97 💬
130 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Adalimumab 💬 Adalimumab [22] 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
131 VEGFA 💬 [24] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Focal adhesion, Integrin signaling, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Renal cell carcinoma, Pancreatic cancer, Bladder cancer, Rheumatoid arthritis, Fluid shear stress and atherosclerosis Aflibercept 💬 Aflibercept [2] 90, 166 💬
132 VEGFB 💬 [10] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Integrin signaling, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Pathways in cancer Aflibercept 💬 Aflibercept [2] 90, 166 💬