Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL10 [4] IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 2 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
| 3 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 4 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 5 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 6 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
| 7 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 |
| 8 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
| 9 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
| 10 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10400 D10400 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 |
| 11 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 12 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 13 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 14 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
| 15 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
| 16 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 17 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 18 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 19 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 20 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
| 21 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 22 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 23 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
| 24 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PRKCD [1] PRKCD 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
| 25 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
| 26 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
| 27 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 28 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
| 29 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00903 D00903 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 30 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00904 D00904 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 31 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 32 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
| 33 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
| 34 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
| 35 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 36 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01475 D01475 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 37 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02290 D02290 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 38 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 39 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 40 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 41 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 42 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 43 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01565 D01565 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 44 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02110 D02110 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 45 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
| 46 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00813 D00813 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 47 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 48 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
| 49 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
| 50 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
| 51 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
| 52 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
| 53 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
| 54 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
| 55 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
| 56 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
| 57 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
| 58 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
| 59 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 60 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 61 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 62 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 63 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 64 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 65 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 66 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
SYK [1] SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 |
| 67 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 68 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 69 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 70 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 71 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 72 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 73 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
| 74 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
| 75 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 76 | Caffeine metabolism 💬 Related to 1 target gene, 2 drugs (DrugBank) and 8 diseases in DDrare |
XDH [1] XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 [6] 6 , 46, 57, 66, 96, 97 💬 |
| 77 | Caffeine metabolism 💬 Related to 1 target gene, 2 drugs (DrugBank) and 8 diseases in DDrare |
XDH [1] XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 |
| 78 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D04641 D04641 💬 |
Istradefylline | 006 [1] 6 💬 |
| 79 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D09717 D09717 💬 |
Preladenant | 006 [1] 6 💬 |
| 80 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 81 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D10174 D10174 💬 |
Tozadenant | 006 [1] 6 💬 |
| 82 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 83 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
| 84 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [4] ADORA2A, PDE1A, PDE1B, PDE1C 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 85 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [2] ADORA2A, PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 86 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2A [2] ADORA2A, PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 87 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
| 88 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
| 89 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 90 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 91 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 92 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 93 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01692 D01692 💬 |
Alfuzosin | 013 [1] 13 💬 |
| 94 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D07124 D07124 💬 |
Alfuzosin | 013 [1] 13 💬 |
| 95 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01965 D01965 💬 |
Silodosin | 006 [2] 6 , 13 💬 |
| 96 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00608 D00608 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
| 97 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D07874 D07874 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
| 98 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D02268 D02268 💬 |
Ergoloid mesylate | 006 [2] 6 , 206 💬 |
| 99 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08064 D08064 💬 |
Ifenprodil | 085 [1] 85 💬 |
| 100 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
| 101 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
| 102 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 103 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 104 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00511 D00511 💬 |
Phenylephrine | 022 [1] 22 💬 |
| 105 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08365 D08365 💬 |
Phenylephrine | 022 [1] 22 💬 |
| 106 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00610 D00610 💬 |
Terazosin | 006 [1] 6 💬 |
| 107 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08569 D08569 💬 |
Terazosin | 006 [1] 6 💬 |
| 108 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 109 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [4] ADRA1A, ADRA1B, ADRA1D, ADRB1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 110 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 111 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 112 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
| 113 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
| 114 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
| 115 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 116 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 117 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 118 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 119 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 120 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 121 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 122 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 123 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 124 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 125 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRA1A [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 126 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
| 127 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 128 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 129 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
| 130 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 131 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 132 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 133 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 134 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 135 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 136 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 137 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 138 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 139 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
| 140 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
| 141 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 142 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00603 D00603 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 143 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 144 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00483 D00483 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 145 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 146 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
| 147 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 148 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 149 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 150 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
| 151 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
| 152 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
| 153 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00687 D00687 💬 |
Salmeterol | 299 [1] 299 💬 |
| 154 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
| 155 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00688 D00688 💬 |
Terbutaline | 118 [1] 118 💬 |
| 156 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
| 157 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
| 158 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D09535 D09535 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 |
| 159 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 160 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 161 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 162 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 163 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 164 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
| 165 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 166 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 167 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
| 168 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 169 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AGTR1 [2] AGTR1, EDNRA 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
| 170 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AVPR1A [1] AVPR1A 💬 |
D01236 D01236 💬 |
Conivaptan | 086 [1] 86 💬 |
| 171 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AVPR1A [1] AVPR1A 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
| 172 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AVPR1A [2] AVPR1A, AVPR1B 💬 |
D06672 D06672 💬 |
Terlipressin | 299 [1] 299 💬 |
| 173 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
AVPR1A [2] AVPR1A, AVPR1B 💬 |
D00101 D00101 💬 |
Vasopressin | 210 [1] 210 💬 |
| 174 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 175 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 176 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 177 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 178 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 179 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 180 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 181 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 182 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 183 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 184 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 185 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 186 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 187 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 188 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 189 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 190 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 191 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 192 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 193 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 194 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
| 195 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
| 196 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CD38 [1] CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 [5] 16, 28, 49, 63, 222 💬 |
| 197 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CD38 [1] CD38 💬 |
D11050 D11050 💬 |
Isatuximab | 028 [2] 28, 61 💬 |
| 198 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CD38 [1] CD38 💬 |
D11945 D11945 💬 |
Mezagitamab | 066 [1] 66 💬 |
| 199 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 200 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 201 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 202 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 203 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 204 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D01000 D01000 💬 |
Bethanechol | 098 [1] 98 💬 |
| 205 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
| 206 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
| 207 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
| 208 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00722 D00722 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
| 209 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00481 D00481 💬 |
Propantheline | 026 [1] 26 💬 |
| 210 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
| 211 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00787 D00787 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
| 212 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
| 213 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 [3] 6 , 13, 19 💬 |
| 214 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM5, CHRNA7 💬 |
D00765 D00765 💬 |
Rocuronium | 296 [1] 296 💬 |
| 215 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 216 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 217 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 218 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM1 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 219 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 [1] 6 💬 |
| 220 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 221 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D02200 D02200 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 222 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D05478 D05478 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 223 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00661 D00661 💬 |
Cevimeline | 053 [1] 53 💬 |
| 224 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 [1] 53 💬 |
| 225 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01699 D01699 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
| 226 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
| 227 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01269 D01269 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
| 228 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
| 229 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
| 230 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01148 D01148 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
| 231 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRNA7 [1] CHRNA7 💬 |
D03365 D03365 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 232 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRNA7 [1] CHRNA7 💬 |
D05156 D05156 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 233 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CHRNA7 [1] CHRNA7 💬 |
D05157 D05157 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 234 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [6] 19, 20, 51, 65, 285, 299 💬 |
| 235 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CYSLTR1 [1] CYSLTR1 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
| 236 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CYSLTR1 [1] CYSLTR1 💬 |
D00529 D00529 💬 |
Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬 |
| 237 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CYSLTR1 [1] CYSLTR1 💬 |
D08229 D08229 💬 |
Montelukast | 006 [8] 6 , 13, 46, 61, 63, 85, 98, 228 💬 |
| 238 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CYSLTR1 [1] CYSLTR1 💬 |
D06659 D06659 💬 |
Tipelukast | 085 [1] 85 💬 |
| 239 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D02004 D02004 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 240 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 241 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
| 242 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00502 D00502 💬 |
Pergolide | 006 [1] 6 💬 |
| 243 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
| 244 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
| 245 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 246 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 247 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
| 248 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
| 249 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D11431 D11431 💬 |
Tavapadon | 006 [1] 6 💬 |
| 250 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
| 251 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
| 252 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07741 D07741 💬 |
Zibotentan | 051 [1] 51 💬 |
| 253 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 254 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 255 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
| 256 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 257 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 258 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 259 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 260 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 261 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 262 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 263 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 264 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FGF23 [1] FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 [1] 238 💬 |
| 265 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
| 266 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
| 267 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
| 268 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
| 269 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
| 270 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FLT1 [6] FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 271 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FLT1 [6] FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 272 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 273 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 274 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 275 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 276 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 277 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 278 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 279 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 280 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 281 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
| 282 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 283 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 284 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
| 285 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 286 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 287 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
| 288 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00664 D00664 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
| 289 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07662 D07662 💬 |
Cetirizine | 013 [4] 13, 28, 35, 300 💬 |
| 290 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00665 D00665 💬 |
Chlorpheniramine | 014 [1] 14 💬 |
| 291 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00668 D00668 💬 |
Chlorpheniramine | 014 [1] 14 💬 |
| 292 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07398 D07398 💬 |
Chlorpheniramine | 014 [1] 14 💬 |
| 293 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07803 D07803 💬 |
Chlorpheniramine | 014 [1] 14 💬 |
| 294 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00666 D00666 💬 |
Clemastine | 013 [1] 13 💬 |
| 295 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03535 D03535 💬 |
Clemastine | 013 [1] 13 💬 |
| 296 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03693 D03693 💬 |
Desloratadine | 013 [1] 13 💬 |
| 297 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07803 D07803 💬 |
Dexchlorpheniramine | 013 [2] 13, 49 💬 |
| 298 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
| 299 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
| 300 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
| 301 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
| 302 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
| 303 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 [10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
| 304 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D01172 D01172 💬 |
Diphenylpyraline | 098 [1] 98 💬 |
| 305 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D01627 D01627 💬 |
Diphenylpyraline | 098 [1] 98 💬 |
| 306 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07862 D07862 💬 |
Diphenylpyraline | 098 [1] 98 💬 |
| 307 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00814 D00814 💬 |
Doxepin | 006 [1] 6 💬 |
| 308 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07875 D07875 💬 |
Doxepin | 006 [1] 6 💬 |
| 309 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00671 D00671 💬 |
Fexofenadine | 013 [2] 13, 46 💬 |
| 310 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07958 D07958 💬 |
Fexofenadine | 013 [2] 13, 46 💬 |
| 311 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D07402 D07402 💬 |
Levocetirizine | 061 [1] 61 💬 |
| 312 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00364 D00364 💬 |
Loratadine | 013 [4] 13, 46, 89, 98 💬 |
| 313 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00480 D00480 💬 |
Promethazine | 096 [1] 96 💬 |
| 314 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D00494 D00494 💬 |
Promethazine | 096 [1] 96 💬 |
| 315 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D01242 D01242 💬 |
Promethazine | 096 [1] 96 💬 |
| 316 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [1] HRH1 💬 |
D03290 D03290 💬 |
Promethazine | 096 [1] 96 💬 |
| 317 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [2] HRH1, HRH2 💬 |
D08040 D08040 💬 |
Histamine | 013 [1] 13 💬 |
| 318 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH1 [2] HRH1, PTAFR 💬 |
D07407 D07407 💬 |
Rupatadine | 046 [1] 46 💬 |
| 319 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00295 D00295 💬 |
Cimetidine | 002 [2] 2 , 254 💬 |
| 320 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D03503 D03503 💬 |
Cimetidine | 002 [2] 2 , 254 💬 |
| 321 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 [7] 6 , 46, 61, 86, 98, 107, 300 💬 |
| 322 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00422 D00422 💬 |
Ranitidine | 013 [2] 13, 65 💬 |
| 323 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HRH2 [1] HRH2 💬 |
D00673 D00673 💬 |
Ranitidine | 013 [2] 13, 65 💬 |
| 324 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 |
| 325 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 [1] 21 💬 |
| 326 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D09645 D09645 💬 |
Nelotanserin | 006 [1] 6 💬 |
| 327 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D00458 D00458 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
| 328 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D08456 D08456 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
| 329 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [1] HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 |
| 330 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 |
| 331 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D00820 D00820 💬 |
Trazodone | 002 [1] 2 💬 |
| 332 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [3] HTR2A, HTR2B, HTR2C 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
| 333 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [2] HTR2A, HTR2C 💬 |
D00283 D00283 💬 |
Clozapine | 006 [1] 6 💬 |
| 334 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [2] HTR2A, HTR4 💬 |
D00274 D00274 💬 |
Cisapride | 013 [1] 13 💬 |
| 335 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A [2] HTR2A, HTR4 💬 |
D02092 D02092 💬 |
Cisapride | 013 [1] 13 💬 |
| 336 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2C [1] HTR2C 💬 |
D02578 D02578 💬 |
Agomelatine | 006 [1] 6 💬 |
| 337 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D08236 D08236 💬 |
Mosapride | 096 [1] 96 💬 |
| 338 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D09205 D09205 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 |
| 339 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D09693 D09693 💬 |
Velusetrag | 099 [1] 99 💬 |
| 340 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
KDR [2] KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
| 341 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
| 342 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
OXTR [1] OXTR 💬 |
D03008 D03008 💬 |
Atosiban | 118 [1] 118 💬 |
| 343 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
OXTR [1] OXTR 💬 |
D07229 D07229 💬 |
Carbetocin | 193 [1] 193 💬 |
| 344 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
OXTR [1] OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 [6] 6 , 72, 127, 193, 206, 226 💬 |
| 345 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
P2RX3 [1] P2RX3 💬 |
D11349 D11349 💬 |
Gefapixant | 085 [2] 85, 226 💬 |
| 346 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 347 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
| 348 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
| 349 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 350 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 351 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 352 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 353 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 354 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 355 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
| 356 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 357 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 358 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
| 359 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PTGER1 [1] PTGER1 💬 |
D00180 D00180 💬 |
Alprostadil | 051 [2] 51, 70 💬 |
| 360 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PTGER1 [1] PTGER1 💬 |
D02705 D02705 💬 |
Alprostadil | 051 [2] 51, 70 💬 |
| 361 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PTGER1 [1] PTGER1 💬 |
D02722 D02722 💬 |
Limaprost | 070 [1] 70 💬 |
| 362 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PTGER3 [1] PTGER3 💬 |
D00419 D00419 💬 |
Misoprostol | 046 [3] 46, 70, 271 💬 |
| 363 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PTGFR [1] PTGFR 💬 |
D06274 D06274 💬 |
Tafluprost | 299 [1] 299 💬 |
| 364 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PTGFR [1] PTGFR 💬 |
D08661 D08661 💬 |
Unoprostone | 090 [1] 90 💬 |
| 365 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
TACR1 [1] TACR1 💬 |
D09378 D09378 💬 |
Serlopitant | 036 [1] 36 💬 |
| 366 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
TBXA2R [1] TBXA2R 💬 |
D01896 D01896 💬 |
Cilostazol | 051 [3] 51, 70, 124 💬 |
| 367 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
TBXA2R [1] TBXA2R 💬 |
D04500 D04500 💬 |
Ifetroban | 051 [3] 51, 86, 113 💬 |
| 368 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
TBXA2R [1] TBXA2R 💬 |
D01128 D01128 💬 |
Ramatroban | 013 [1] 13 💬 |
| 369 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
TNNC2 [1] TNNC2 💬 |
D11363 D11363 💬 |
Reldesemtiv | 002 [2] 2 , 3 💬 |
| 370 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
TRHR [1] TRHR 💬 |
D00176 D00176 💬 |
Protirelin | 080 [1] 80 💬 |
| 371 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 372 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
| 373 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
VEGFA [2] VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
| 374 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA2A 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 375 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA2A 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
| 376 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [9] ADORA1, ADORA2A, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 377 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 378 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 379 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
| 380 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
| 381 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 382 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 383 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 384 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 385 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D04641 D04641 💬 |
Istradefylline | 006 [1] 6 💬 |
| 386 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D09717 D09717 💬 |
Preladenant | 006 [1] 6 💬 |
| 387 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
| 388 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D10174 D10174 💬 |
Tozadenant | 006 [1] 6 💬 |
| 389 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 390 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 391 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
| 392 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 393 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 394 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
| 395 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 396 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 397 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 398 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 399 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 400 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 401 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 402 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 403 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 404 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
| 405 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 406 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 407 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
| 408 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
| 409 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
| 410 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 411 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 412 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 413 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
| 414 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 415 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 416 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00483 D00483 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 417 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08443 D08443 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 418 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 419 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 420 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 421 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 422 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 423 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00603 D00603 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 424 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 425 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
| 426 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 427 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 428 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 429 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
| 430 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
| 431 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
| 432 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00687 D00687 💬 |
Salmeterol | 299 [1] 299 💬 |
| 433 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
| 434 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00688 D00688 💬 |
Terbutaline | 118 [1] 118 💬 |
| 435 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
| 436 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
| 437 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
| 438 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
| 439 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 440 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 441 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 442 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 443 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 444 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 445 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 446 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 447 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 448 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 449 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 450 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 451 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 452 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 453 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 454 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 455 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 456 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 457 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 458 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [6] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 459 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 460 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 [1] 299 💬 |
| 461 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 [1] 299 💬 |
| 462 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 [1] 299 💬 |
| 463 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CFTR [1] CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 [1] 299 💬 |
| 464 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CFTR [1] CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 [1] 299 💬 |
| 465 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 [1] 299 💬 |
| 466 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00113 D00113 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 467 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D01077 D01077 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 468 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D02069 D02069 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 469 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D03011 D03011 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 470 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D03814 D03814 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 471 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D01000 D01000 💬 |
Bethanechol | 098 [1] 98 💬 |
| 472 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
| 473 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
| 474 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
| 475 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00722 D00722 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
| 476 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00481 D00481 💬 |
Propantheline | 026 [1] 26 💬 |
| 477 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00765 D00765 💬 |
Rocuronium | 296 [1] 296 💬 |
| 478 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
| 479 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00787 D00787 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
| 480 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
| 481 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [2] CHRM1, CHRM2 💬 |
D00397 D00397 💬 |
Tropicamide | 006 [3] 6 , 13, 19 💬 |
| 482 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM2, DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 483 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM2, DRD2 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 484 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM2, DRD2 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 485 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM1 [3] CHRM1, CHRM2, DRD2 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 486 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM2 [1] CHRM2 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 [1] 6 💬 |
| 487 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM2 [1] CHRM2 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 488 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM2 [1] CHRM2 💬 |
D02200 D02200 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 489 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CHRM2 [1] CHRM2 💬 |
D05478 D05478 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 490 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CRHR1 [2] CRHR1, CRHR2 💬 |
D03905 D03905 💬 |
Corticorelin | 075 [2] 75, 205 💬 |
| 491 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
CRHR1 [2] CRHR1, CRHR2 💬 |
D03592 D03592 💬 |
Corticorelin ovine triflutate | 075 [1] 75 💬 |
| 492 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 493 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 494 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
| 495 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00502 D00502 💬 |
Pergolide | 006 [1] 6 💬 |
| 496 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
| 497 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
| 498 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 499 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 500 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
| 501 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [3] DRD1, DRD2, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
| 502 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 [2] DRD1, DRD5 💬 |
D11431 D11431 💬 |
Tavapadon | 006 [1] 6 💬 |
| 503 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
| 504 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
| 505 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
| 506 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
| 507 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
| 508 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00136 D00136 💬 |
Haloperidol | 008 [1] 8 💬 |
| 509 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01898 D01898 💬 |
Haloperidol | 008 [1] 8 💬 |
| 510 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
| 511 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
| 512 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07309 D07309 💬 |
Melperone | 006 [1] 6 💬 |
| 513 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00726 D00726 💬 |
Metoclopramide | 051 [1] 51 💬 |
| 514 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D02213 D02213 💬 |
Metoclopramide | 051 [1] 51 💬 |
| 515 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05008 D05008 💬 |
Metoclopramide | 051 [1] 51 💬 |
| 516 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
| 517 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07305 D07305 💬 |
Piribedil | 006 [1] 6 💬 |
| 518 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
| 519 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
| 520 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
| 521 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00458 D00458 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
| 522 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08456 D08456 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
| 523 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 |
| 524 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
| 525 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
| 526 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05768 D05768 💬 |
Rotigotine | 006 [2] 6 , 127 💬 |
| 527 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
| 528 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
| 529 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
| 530 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08590 D08590 💬 |
Tiapride | 008 [1] 8 💬 |
| 531 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00799 D00799 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
| 532 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01448 D01448 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
| 533 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08636 D08636 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
| 534 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [2] DRD2, HTR1A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 |
| 535 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [2] DRD2, HTR1A 💬 |
D00702 D00702 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
| 536 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [2] DRD2, HTR1A 💬 |
D07593 D07593 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
| 537 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [2] DRD2, HTR1A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 [1] 21 💬 |
| 538 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [2] DRD2, HTR1A 💬 |
D09397 D09397 💬 |
Pardoprunox | 006 [1] 6 💬 |
| 539 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [2] DRD2, HTR6 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 540 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 [2] DRD2, HTR6 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 541 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
| 542 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 543 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 544 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
| 545 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
| 546 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
| 547 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07741 D07741 💬 |
Zibotentan | 051 [1] 51 💬 |
| 548 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 [2] 13, 206 💬 |
| 549 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D08861 D08861 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 |
| 550 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [7] 2 , 10, 13, 18, 65, 149, 206 💬 |
| 551 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GHSR [1] GHSR 💬 |
D10563 D10563 💬 |
Macimorelin | 078 [1] 78 💬 |
| 552 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GLP1R [1] GLP1R 💬 |
D09889 D09889 💬 |
Dulaglutide | 013 [2] 13, 299 💬 |
| 553 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GLP1R [1] GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 [6] 6 , 17, 72, 78, 193, 233 💬 |
| 554 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GLP1R [1] GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 [3] 6 , 75, 193 💬 |
| 555 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GLP1R [1] GLP1R 💬 |
D09729 D09729 💬 |
Lixisenatide | 006 [1] 6 💬 |
| 556 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GLP1R [1] GLP1R 💬 |
D10025 D10025 💬 |
Semaglutide | 006 [1] 6 💬 |
| 557 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
| 558 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
| 559 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
| 560 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 561 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 562 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 563 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 564 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 565 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 566 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 567 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
| 568 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 569 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 570 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
| 571 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 572 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 573 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
HTR1A [1] HTR1A 💬 |
D10184 D10184 💬 |
Vortioxetine | 006 [1] 6 💬 |
| 574 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
HTR1B [2] HTR1B, HTR1D 💬 |
D00415 D00415 💬 |
Zolmitriptan | 006 [1] 6 💬 |
| 575 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D00274 D00274 💬 |
Cisapride | 013 [1] 13 💬 |
| 576 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D02092 D02092 💬 |
Cisapride | 013 [1] 13 💬 |
| 577 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D08236 D08236 💬 |
Mosapride | 096 [1] 96 💬 |
| 578 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D09205 D09205 💬 |
Prucalopride | 013 [3] 13, 51, 96 💬 |
| 579 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
HTR4 [1] HTR4 💬 |
D09693 D09693 💬 |
Velusetrag | 099 [1] 99 💬 |
| 580 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 581 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 582 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 583 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 584 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [15] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 |
| 585 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00284 D00284 💬 |
Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬 |
| 586 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 587 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
| 588 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 589 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
OXTR [1] OXTR 💬 |
D03008 D03008 💬 |
Atosiban | 118 [1] 118 💬 |
| 590 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
OXTR [1] OXTR 💬 |
D07229 D07229 💬 |
Carbetocin | 193 [1] 193 💬 |
| 591 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
OXTR [1] OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 [6] 6 , 72, 127, 193, 206, 226 💬 |
| 592 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 593 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
| 594 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
| 595 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 051 [3] 51, 70, 124 💬 |
| 596 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
| 597 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
| 598 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
| 599 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
| 600 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE4A [1] PDE4A 💬 |
D00302 D00302 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 |
| 601 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
| 602 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 [2] 84, 299 💬 |
| 603 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01783 D01783 💬 |
Rolipram | 008 [2] 8 , 13 💬 |
| 604 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 605 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 606 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 |
| 607 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D11208 D11208 💬 |
Elafibranor | 093 [1] 93 💬 |
| 608 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 [5] 8 , 79, 93, 94, 265 💬 |
| 609 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D10711 D10711 💬 |
Pemafibrate | 093 [1] 93 💬 |
| 610 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PTGER2 [2] PTGER2, PTGER3 💬 |
D00419 D00419 💬 |
Misoprostol | 046 [3] 46, 70, 271 💬 |
| 611 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 612 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
| 613 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [1] 51 💬 |
| 614 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
SSTR1 [3] SSTR1, SSTR2, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 [3] 67, 74, 75 💬 |
| 615 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
SSTR1 [3] SSTR1, SSTR2, SSTR5 💬 |
D07431 D07431 💬 |
Somatostatin | 067 [2] 67, 78 💬 |
| 616 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
SSTR2 [1] SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 |
| 617 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
SSTR2 [1] SSTR2 💬 |
D06495 D06495 💬 |
Octreotide | 067 [7] 67, 75, 84, 85, 89, 193, 227 💬 |
| 618 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
AMY2A [3] AMY2A, AMY2B, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
| 619 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
| 620 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
| 621 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 622 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 623 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 624 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 625 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 626 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 627 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 628 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 629 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 630 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 631 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 632 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 633 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 634 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 635 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 636 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 637 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 638 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 639 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 640 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 641 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
TAS1R2 [2] TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 [5] 6 , 13, 67, 86, 230 💬 |
| 642 | Carbon metabolism 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 643 | Carbon metabolism 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
HAO1 [1] HAO1 💬 |
D11925 D11925 💬 |
Lumasiran | 234 [1] 234 💬 |
| 644 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
| 645 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
| 646 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 647 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 648 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 649 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 650 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 651 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 652 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 653 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 654 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 655 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 656 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 657 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 658 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 659 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 660 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 661 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 662 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 663 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 664 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA2D1 [2] CACNA2D1, CACNA2D2 💬 |
D11203 D11203 💬 |
Mirogabalin | 070 [1] 70 💬 |
| 665 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
| 666 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
| 667 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 668 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD22 [1] CD22 💬 |
D04036 D04036 💬 |
Epratuzumab | 049 [1] 49 💬 |
| 669 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD274 [1] CD274 💬 |
D10773 D10773 💬 |
Atezolizumab | 085 [1] 85 💬 |
| 670 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD274 [1] CD274 💬 |
D10808 D10808 💬 |
Durvalumab | 085 [1] 85 💬 |
| 671 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
| 672 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
| 673 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
| 674 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
| 675 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD58 [1] CD58 💬 |
D02800 D02800 💬 |
Alefacept | 037 [6] 37, 60, 65, 164, 284, 285 💬 |
| 676 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
| 677 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
| 678 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 [1] 159 💬 |
| 679 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
| 680 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
HLA-A [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
| 681 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 [1] 13 💬 |
| 682 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
| 683 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
| 684 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
| 685 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
| 686 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
| 687 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
PDCD1 [1] PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
| 688 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
PDCD1 [1] PDCD1 💬 |
D10574 D10574 💬 |
Pembrolizumab | 025 [2] 25, 285 💬 |
| 689 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 690 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 691 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 692 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 693 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 694 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 695 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 696 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
| 697 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
| 698 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
PLK1 [1] PLK1 💬 |
D10154 D10154 💬 |
Rigosertib | 036 [1] 36 💬 |
| 699 | Cell cycle 💬 Related to 9 target genes, 9 drugs (DrugBank) and 23 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 700 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 701 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 702 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 703 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 704 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 705 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 706 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 707 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 708 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 709 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 710 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 711 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 712 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 713 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 714 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 715 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 716 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 717 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 718 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
| 719 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
HLA-A [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 [4] 2 , 13, 96, 156 💬 |
| 720 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
| 721 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL1A [1] IL1A 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 722 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL1A [2] IL1A, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 723 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL6 [1] IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 724 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 725 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 726 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 727 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 728 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 729 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 730 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
| 731 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
| 732 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 733 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 734 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
| 735 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 736 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 737 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 738 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 739 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
| 740 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 741 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 742 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
| 743 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 744 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 745 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 746 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 747 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 748 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 749 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 750 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 751 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 752 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 753 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 754 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 755 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
| 756 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
| 757 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
| 758 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FLT3 [2] FLT3, KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
| 759 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FLT3 [5] FLT3, KIT, PDGFRA, PDGFRB, RET 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 760 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FLT3 [5] FLT3, KIT, PDGFRA, PDGFRB, RET 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 761 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 762 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 763 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
| 764 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
KIT [2] KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 765 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 766 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 767 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
KIT [2] KIT, PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 768 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
KIT [2] KIT, PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 769 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 770 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 771 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 772 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 773 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
| 774 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 775 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 776 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
| 777 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 778 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 779 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA3 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 780 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [2] ADORA1, ADORA3 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
| 781 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
| 782 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
| 783 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 784 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 785 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 786 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 787 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 788 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 789 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 [5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 790 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA3 [1] ADORA3 💬 |
D10971 D10971 💬 |
Piclidenoson | 046 [1] 46 💬 |
| 791 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01692 D01692 💬 |
Alfuzosin | 013 [1] 13 💬 |
| 792 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D07124 D07124 💬 |
Alfuzosin | 013 [1] 13 💬 |
| 793 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01965 D01965 💬 |
Silodosin | 006 [2] 6 , 13 💬 |
| 794 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00608 D00608 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
| 795 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D07874 D07874 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
| 796 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08064 D08064 💬 |
Ifenprodil | 085 [1] 85 💬 |
| 797 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 798 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
| 799 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 800 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 801 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00511 D00511 💬 |
Phenylephrine | 022 [1] 22 💬 |
| 802 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08365 D08365 💬 |
Phenylephrine | 022 [1] 22 💬 |
| 803 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00610 D00610 💬 |
Terazosin | 006 [1] 6 💬 |
| 804 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08569 D08569 💬 |
Terazosin | 006 [1] 6 💬 |
| 805 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D02268 D02268 💬 |
Ergoloid mesylate | 006 [2] 6 , 206 💬 |
| 806 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
| 807 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 [3] 118, 280, 288 💬 |
| 808 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
| 809 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
| 810 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
| 811 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 812 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 813 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 814 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 815 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 816 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 817 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 818 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 819 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 820 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 821 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 822 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 823 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 824 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [1] ADRA2A 💬 |
D00606 D00606 💬 |
Guanfacine | 193 [1] 193 💬 |
| 825 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [1] ADRA2A 💬 |
D08031 D08031 💬 |
Guanfacine | 193 [1] 193 💬 |
| 826 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [1] ADRA2A 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
| 827 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01008 D01008 💬 |
Apraclonidine | 011 [1] 11 💬 |
| 828 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D07461 D07461 💬 |
Apraclonidine | 011 [1] 11 💬 |
| 829 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D02076 D02076 💬 |
Brimonidine | 013 [2] 13, 90 💬 |
| 830 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D07540 D07540 💬 |
Brimonidine | 013 [2] 13, 90 💬 |
| 831 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 832 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 833 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 834 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 835 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00281 D00281 💬 |
Clonidine | 006 [4] 6 , 65, 70, 78 💬 |
| 836 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00604 D00604 💬 |
Clonidine | 006 [4] 6 , 65, 70, 78 💬 |
| 837 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00283 D00283 💬 |
Clozapine | 006 [1] 6 💬 |
| 838 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
| 839 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D01205 D01205 💬 |
Dexmedetomidine | 002 [13] 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 212, 215, 226, 280 💬 |
| 840 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D04375 D04375 💬 |
Guanabenz | 002 [2] 2 , 13 💬 |
| 841 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00405 D00405 💬 |
Methyldopa | 323 [1] 323 💬 |
| 842 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08205 D08205 💬 |
Methyldopa | 323 [1] 323 💬 |
| 843 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08482 D08482 💬 |
Rilmenidine | 008 [1] 8 💬 |
| 844 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D00776 D00776 💬 |
Tizanidine | 013 [1] 13 💬 |
| 845 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08611 D08611 💬 |
Tizanidine | 013 [1] 13 💬 |
| 846 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRA2A [3] ADRA2A, ADRA2B, ADRA2C 💬 |
D08685 D08685 💬 |
Yohimbine | 006 [1] 6 💬 |
| 847 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
| 848 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 849 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 850 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
| 851 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 852 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 853 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 854 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 855 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 856 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 857 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 858 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 859 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 860 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
| 861 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
| 862 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 863 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00603 D00603 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 864 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 865 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00483 D00483 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 866 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 867 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
| 868 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 869 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 870 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 871 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
| 872 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
| 873 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
| 874 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00687 D00687 💬 |
Salmeterol | 299 [1] 299 💬 |
| 875 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
| 876 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00688 D00688 💬 |
Terbutaline | 118 [1] 118 💬 |
| 877 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
| 878 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
| 879 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D09535 D09535 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 |
| 880 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 881 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 882 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 883 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 884 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 885 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
| 886 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 887 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 888 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
| 889 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 890 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
AGTR1 [2] AGTR1, EDNRA 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
| 891 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
| 892 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
| 893 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 894 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 895 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 896 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 897 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 898 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 899 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 900 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 901 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 902 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 903 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 904 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 905 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 906 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 907 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 908 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 909 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 910 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 911 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
| 912 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
| 913 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07741 D07741 💬 |
Zibotentan | 051 [1] 51 💬 |
| 914 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 915 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 916 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
EDNRA [2] EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
| 917 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 918 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
| 919 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
| 920 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
| 921 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
| 922 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
| 923 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 924 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 925 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 926 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 927 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
| 928 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 929 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR1 [2] NPR1, NPR2 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
| 930 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR2 [1] NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 [1] 276 💬 |
| 931 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D00729 D00729 💬 |
Loperamide | 013 [2] 13, 97 💬 |
| 932 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D07113 D07113 💬 |
Loperamide | 013 [2] 13, 97 💬 |
| 933 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D08144 D08144 💬 |
Loperamide | 013 [2] 13, 97 💬 |
| 934 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D00843 D00843 💬 |
Nalbuphine | 085 [1] 85 💬 |
| 935 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D08246 D08246 💬 |
Nalbuphine | 085 [1] 85 💬 |
| 936 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05111 D05111 💬 |
Nalmefene | 006 [1] 6 💬 |
| 937 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D01340 D01340 💬 |
Naloxone | 006 [2] 6 , 226 💬 |
| 938 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D08249 D08249 💬 |
Naloxone | 006 [2] 6 , 226 💬 |
| 939 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
| 940 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
| 941 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D03783 D03783 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
| 942 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
| 943 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05462 D05462 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
| 944 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 945 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
| 946 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
| 947 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 051 [3] 51, 70, 124 💬 |
| 948 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
| 949 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
| 950 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
| 951 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
| 952 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D00302 D00302 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 |
| 953 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 954 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 955 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 |
| 956 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 [2] 86, 210 💬 |
| 957 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02731 D02731 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
| 958 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D03260 D03260 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
| 959 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
| 960 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 961 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
| 962 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 963 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 964 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
| 965 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PRKCE [1] PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
| 966 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 967 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 968 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
| 969 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [1] 51 💬 |
| 970 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00620 D00620 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 |
| 971 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D07499 D07499 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 |
| 972 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
| 973 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D01069 D01069 💬 |
Cilazapril | 066 [1] 66 💬 |
| 974 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D07699 D07699 💬 |
Cilazapril | 066 [1] 66 💬 |
| 975 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 |
| 976 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 |
| 977 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D08068 D08068 💬 |
Imidapril | 067 [1] 67 💬 |
| 978 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
| 979 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
| 980 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00623 D00623 💬 |
Moexipril | 093 [1] 93 💬 |
| 981 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D08225 D08225 💬 |
Moexipril | 093 [1] 93 💬 |
| 982 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 983 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 984 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 [1] 19 💬 |
| 985 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 [1] 19 💬 |
| 986 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
ACE [1] ACE 💬 |
D00421 D00421 💬 |
Ramipril | 046 [7] 46, 49, 66, 67, 113, 218, 257 💬 |
| 987 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
C3 [1] C3 💬 |
D11613 D11613 💬 |
Pegcetacoplan | 002 [3] 2 , 62, 222 💬 |
| 988 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 989 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
| 990 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 [1] 46 💬 |
| 991 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
| 992 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
CD3E [1] CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 [1] 49 💬 |
| 993 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
| 994 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
| 995 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
| 996 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
| 997 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 998 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 999 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 1000 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 1001 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 1002 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 1003 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
| 1004 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
| 1005 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1006 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1007 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1008 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 1009 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 1010 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 1011 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 1012 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 1013 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 1014 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 1015 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 1016 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
| 1017 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
| 1018 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 1019 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
| 1020 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
| 1021 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 1022 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
| 1023 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00903 D00903 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 1024 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00904 D00904 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 1025 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 1026 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
| 1027 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
| 1028 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
| 1029 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 1030 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01475 D01475 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 1031 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02290 D02290 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 1032 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 1033 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 1034 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 1035 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 1036 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 1037 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01565 D01565 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 1038 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02110 D02110 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 1039 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
| 1040 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00813 D00813 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 1041 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 1042 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
| 1043 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
| 1044 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
| 1045 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
| 1046 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
| 1047 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
| 1048 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
| 1049 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
| 1050 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
| 1051 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
| 1052 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 41 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
| 1053 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 1054 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 1055 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 1056 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 1057 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1058 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1059 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 1060 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 1061 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1062 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1063 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 1064 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1065 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1066 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 1067 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 1068 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1069 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1070 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 1071 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
HMOX1 [1] HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 [1] 254 💬 |
| 1072 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
KEAP1 [1] KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬 |
| 1073 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1074 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1075 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1076 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1077 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
| 1078 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
| 1079 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
| 1080 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
| 1081 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NFE2L2 [1] NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 [1] 18 💬 |
| 1082 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1083 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 [1] NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 1084 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 [1] NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 1085 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 [1] NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 1086 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1087 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1088 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
PRKCD [1] PRKCD 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
| 1089 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 1090 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
SOD1 [1] SOD1 💬 |
D11811 D11811 💬 |
Tofersen | 002 [1] 2 💬 |
| 1091 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
| 1092 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 1093 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 34 drugs (DrugBank) and 42 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
| 1094 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 1095 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 1096 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
| 1097 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00634 D00634 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 1098 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 067 [3] 67, 86, 113 💬 |
| 1099 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
| 1100 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00632 D00632 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 1101 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 1102 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03880 D03880 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 1103 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03881 D03881 💬 |
Dobutamine | 057 [3] 57, 58, 215 💬 |
| 1104 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00644 D00644 💬 |
Esmolol | 058 [1] 58 💬 |
| 1105 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
| 1106 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 1107 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 1108 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
| 1109 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
| 1110 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 1111 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D03415 D03415 💬 |
Carvedilol | 006 [5] 6 , 57, 86, 113, 210 💬 |
| 1112 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
| 1113 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 1114 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00603 D00603 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 1115 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
| 1116 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
| 1117 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
| 1118 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
| 1119 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 1120 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00996 D00996 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 1121 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D02149 D02149 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
| 1122 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 1123 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 [1] 22 💬 |
| 1124 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00483 D00483 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 1125 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [7] 6 , 158, 167, 215, 227, 278, 296 💬 |
| 1126 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 1127 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 1128 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 1129 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
| 1130 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
| 1131 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D01373 D01373 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 1132 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05277 D05277 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 1133 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
| 1134 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
| 1135 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
| 1136 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬 |
| 1137 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00687 D00687 💬 |
Salmeterol | 299 [1] 299 💬 |
| 1138 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
| 1139 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D00688 D00688 💬 |
Terbutaline | 118 [1] 118 💬 |
| 1140 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
| 1141 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
| 1142 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D09535 D09535 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 |
| 1143 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D03338 D03338 💬 |
Calusterone | 002 [3] 2 , 46, 71 💬 |
| 1144 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00586 D00586 💬 |
Flutamide | 081 [1] 81 💬 |
| 1145 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D08250 D08250 💬 |
Nandrolone | 060 [2] 60, 85 💬 |
| 1146 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00955 D00955 💬 |
Nandrolone decanoate | 060 [2] 60, 85 💬 |
| 1147 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00462 D00462 💬 |
Oxandrolone | 211 [2] 211, 285 💬 |
| 1148 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00444 D00444 💬 |
Stanozolol | 060 [1] 60 💬 |
| 1149 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 [9] 1 , 2 , 3 , 13, 60, 76, 78, 113, 265 💬 |
| 1150 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 [9] 1 , 2 , 3 , 13, 60, 76, 78, 113, 265 💬 |
| 1151 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 [9] 1 , 2 , 3 , 13, 60, 76, 78, 113, 265 💬 |
| 1152 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 [9] 1 , 2 , 3 , 13, 60, 76, 78, 113, 265 💬 |
| 1153 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 [9] 1 , 2 , 3 , 13, 60, 76, 78, 113, 265 💬 |
| 1154 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 [9] 1 , 2 , 3 , 13, 60, 76, 78, 113, 265 💬 |
| 1155 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D08573 D08573 💬 |
Testosterone decanoate | 113 [1] 113 💬 |
| 1156 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00958 D00958 💬 |
Testosterone enanthate | 013 [2] 13, 113 💬 |
| 1157 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D08574 D08574 💬 |
Testosterone phenylpropionate | 113 [1] 113 💬 |
| 1158 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D00959 D00959 💬 |
Testosterone propionate | 113 [1] 113 💬 |
| 1159 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [1] AR 💬 |
D06087 D06087 💬 |
Testosterone undecanoate | 013 [2] 13, 60 💬 |
| 1160 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [3] AR, ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
| 1161 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR [3] AR, ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
| 1162 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
| 1163 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 1164 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1165 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1166 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1167 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1168 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1169 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1170 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 1171 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1172 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1173 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 1174 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 1175 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1176 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1177 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 1178 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 1179 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1180 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1181 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 |
D03365 D03365 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 1182 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 |
D05156 D05156 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 1183 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 |
D05157 D05157 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 1184 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 |
D00765 D00765 💬 |
Rocuronium | 296 [1] 296 💬 |
| 1185 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
CHRNA4 [2] CHRNA4, CHRNB2 💬 |
D08669 D08669 💬 |
Varenicline | 006 [2] 6 , 18 💬 |
| 1186 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 1187 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1188 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1189 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 1190 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 1191 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1192 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1193 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 1194 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 |
| 1195 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 [1] 74 💬 |
| 1196 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
| 1197 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D11513 D11513 💬 |
Estetrol | 053 [1] 53 💬 |
| 1198 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D11514 D11514 💬 |
Estetrol | 053 [1] 53 💬 |
| 1199 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1200 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1201 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01617 D01617 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1202 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01953 D01953 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1203 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D04061 D04061 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1204 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D04063 D04063 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1205 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D04064 D04064 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1206 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D04065 D04065 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
| 1207 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 [1] 65 💬 |
| 1208 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00185 D00185 💬 |
Estriol | 013 [2] 13, 227 💬 |
| 1209 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01986 D01986 💬 |
Estriol | 013 [2] 13, 227 💬 |
| 1210 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
| 1211 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00575 D00575 💬 |
Mestranol | 046 [2] 46, 49 💬 |
| 1212 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D02217 D02217 💬 |
Raloxifene | 046 [1] 46 💬 |
| 1213 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08465 D08465 💬 |
Raloxifene | 046 [1] 46 💬 |
| 1214 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
| 1215 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [4] 2 , 86, 113, 227 💬 |
| 1216 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 [2] ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
| 1217 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
| 1218 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
| 1219 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
| 1220 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
| 1221 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1222 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1223 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1224 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1225 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 1226 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 1227 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
| 1228 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1229 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D01217 D01217 💬 |
Dydrogesterone | 013 [1] 13 💬 |
| 1230 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D00950 D00950 💬 |
Levonorgestrel | 013 [1] 13 💬 |
| 1231 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D00951 D00951 💬 |
Medroxyprogesterone acetate | 013 [6] 13, 35, 46, 49, 51, 60 💬 |
| 1232 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D08166 D08166 💬 |
Medroxyprogesterone acetate | 013 [6] 13, 35, 46, 49, 51, 60 💬 |
| 1233 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 [1] 76 💬 |
| 1234 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D08167 D08167 💬 |
Megestrol acetate | 076 [1] 76 💬 |
| 1235 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 [1] 75 💬 |
| 1236 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D07222 D07222 💬 |
Nomegestrol | 013 [1] 13 💬 |
| 1237 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D08281 D08281 💬 |
Nomegestrol acetate | 013 [1] 13 💬 |
| 1238 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 [4] 13, 46, 49, 299 💬 |
| 1239 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D00953 D00953 💬 |
Norethisterone | 013 [4] 13, 46, 49, 299 💬 |
| 1240 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 [1] 299 💬 |
| 1241 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 [1] 76 💬 |
| 1242 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PGR [1] PGR 💬 |
D09567 D09567 💬 |
Ulipristal | 010 [1] 10 💬 |
| 1243 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1244 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1245 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 |
| 1246 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D11208 D11208 💬 |
Elafibranor | 093 [1] 93 💬 |
| 1247 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 [5] 8 , 79, 93, 94, 265 💬 |
| 1248 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PPARA [1] PPARA 💬 |
D10711 D10711 💬 |
Pemafibrate | 093 [1] 93 💬 |
| 1249 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1250 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1251 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 1252 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
| 1253 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
| 1254 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |
| 1255 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 1256 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1257 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1258 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 1259 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
| 1260 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
| 1261 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 [2] 113, 299 💬 |
| 1262 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D01125 D01125 💬 |
Calcipotriol | 036 [2] 36, 51 💬 |
| 1263 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
| 1264 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [25] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
| 1265 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D00299 D00299 💬 |
Dihydrotachysterol | 006 [2] 6 , 85 💬 |
| 1266 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D07578 D07578 💬 |
Eldecalcitol | 046 [1] 46 💬 |
| 1267 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬 |
| 1268 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [4] 19, 66, 218, 238 💬 |
| 1269 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
| 1270 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 1271 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
| 1272 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 1273 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1274 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1275 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CCL2 [1] CCL2 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 1276 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CCR2 [2] CCR2, CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
| 1277 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CCR4 [1] CCR4 💬 |
D09761 D09761 💬 |
Mogamulizumab | 026 [1] 26 💬 |
| 1278 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
| 1279 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
| 1280 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [6] 19, 20, 51, 65, 285, 299 💬 |
| 1281 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
| 1282 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
| 1283 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
JAK2 [2] JAK2, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
| 1284 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
JAK2 [2] JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
| 1285 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1286 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1287 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1288 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1289 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1290 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1291 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1292 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
PRKCD [1] PRKCD 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
| 1293 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 1294 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
| 1295 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [1] 51 💬 |
| 1296 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 1297 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1298 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1299 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 1300 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
ANGPTL3 [1] ANGPTL3 💬 |
D11753 D11753 💬 |
Evinacumab | 079 [1] 79 💬 |
| 1301 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
APOC3 [1] APOC3 💬 |
D11648 D11648 💬 |
Volanesorsen | 265 [1] 265 💬 |
| 1302 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
CETP [1] CETP 💬 |
D08855 D08855 💬 |
Anacetrapib | 079 [1] 79 💬 |
| 1303 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
LIPA [1] LIPA 💬 |
D10377 D10377 💬 |
Sebelipase alfa | 019 [1] 19 💬 |
| 1304 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
PCSK9 [1] PCSK9 💬 |
D10335 D10335 💬 |
Alirocumab | 079 [1] 79 💬 |
| 1305 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
PCSK9 [1] PCSK9 💬 |
D10557 D10557 💬 |
Evolocumab | 079 [2] 79, 222 💬 |
| 1306 | Cholesterol metabolism 💬 Related to 5 target genes, 7 drugs (DrugBank) and 4 diseases in DDrare |
PCSK9 [1] PCSK9 💬 |
D11931 D11931 💬 |
Inclisiran | 079 [1] 79 💬 |
| 1307 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 1308 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1309 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1310 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 1311 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 1312 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1313 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1314 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 1315 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1316 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1317 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1318 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1319 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 1320 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 1321 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
| 1322 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 1323 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 1324 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 1325 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
| 1326 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 1327 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 1328 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1329 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1330 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRB [2] PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1331 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1332 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1333 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1334 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D00670 D00670 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
| 1335 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D07869 D07869 💬 |
Donepezil | 005 [9] 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
| 1336 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D02173 D02173 💬 |
Galantamine | 006 [2] 6 , 127 💬 |
| 1337 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D04292 D04292 💬 |
Galantamine | 006 [2] 6 , 127 💬 |
| 1338 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
| 1339 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D08261 D08261 💬 |
Neostigmine | 011 [1] 11 💬 |
| 1340 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D00487 D00487 💬 |
Pyridostigmine | 003 [4] 3 , 6 , 11, 256 💬 |
| 1341 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D02558 D02558 💬 |
Rivastigmine | 005 [3] 5 , 6 , 13 💬 |
| 1342 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D03822 D03822 💬 |
Rivastigmine | 005 [3] 5 , 6 , 13 💬 |
| 1343 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D02068 D02068 💬 |
Tacrine | 046 [3] 46, 271, 299 💬 |
| 1344 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
ACHE [1] ACHE 💬 |
D08555 D08555 💬 |
Tacrine | 046 [3] 46, 271, 299 💬 |
| 1345 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
| 1346 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 1347 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1348 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1349 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1350 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1351 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1352 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1353 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 1354 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1355 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1356 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 1357 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 1358 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1359 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1360 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 1361 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1362 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1363 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 1364 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 1365 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D01077 D01077 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 1366 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02069 D02069 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 1367 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03011 D03011 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 1368 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03814 D03814 💬 |
Atropine | 002 [2] 2 , 299 💬 |
| 1369 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D01000 D01000 💬 |
Bethanechol | 098 [1] 98 💬 |
| 1370 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
| 1371 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1372 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1373 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1374 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1375 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D02212 D02212 💬 |
Ipratropium | 006 [2] 6 , 86 💬 |
| 1376 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
| 1377 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00722 D00722 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
| 1378 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00481 D00481 💬 |
Propantheline | 026 [1] 26 💬 |
| 1379 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
| 1380 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00787 D00787 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
| 1381 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
| 1382 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 [3] 6 , 13, 19 💬 |
| 1383 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM1 [11] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
D00765 D00765 💬 |
Rocuronium | 296 [1] 296 💬 |
| 1384 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 [1] 6 💬 |
| 1385 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 1386 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D02200 D02200 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 1387 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D05478 D05478 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
| 1388 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00661 D00661 💬 |
Cevimeline | 053 [1] 53 💬 |
| 1389 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 [1] 53 💬 |
| 1390 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01699 D01699 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
| 1391 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
| 1392 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01269 D01269 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
| 1393 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
| 1394 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
| 1395 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D01148 D01148 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
| 1396 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
D03365 D03365 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 1397 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
D05156 D05156 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 1398 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRNA3 [6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
D05157 D05157 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
| 1399 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
CHRNA4 [2] CHRNA4, CHRNB2 💬 |
D08669 D08669 💬 |
Varenicline | 006 [2] 6 , 18 💬 |
| 1400 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
FYN [1] FYN 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1401 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
FYN [1] FYN 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1402 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
| 1403 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
| 1404 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
| 1405 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
JAK2 [1] JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
| 1406 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
KCNJ12 [3] KCNJ12, KCNJ3, KCNQ1 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 1407 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
KCNJ12 [3] KCNJ12, KCNJ3, KCNQ1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 1408 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
KCNQ1 [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
| 1409 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1410 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1411 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1412 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1413 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1414 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1415 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 1416 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1417 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 1418 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 1419 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 1420 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 1421 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 1422 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 1423 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1424 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1425 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
| 1426 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
| 1427 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1428 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1429 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1430 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1431 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1432 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1433 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1434 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 1435 | Chronic myeloid leukemia 💬 Related to 17 target genes, 18 drugs (DrugBank) and 29 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 1436 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1437 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1438 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1439 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 1440 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1441 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1442 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1443 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 1444 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1445 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1446 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 1447 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 1448 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1449 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1450 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 1451 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1452 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1453 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1C [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 1454 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 1455 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 1456 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
| 1457 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
| 1458 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
| 1459 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
| 1460 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
| 1461 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 1462 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 1463 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 1464 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 1465 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 1466 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 1467 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 1468 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
| 1469 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 1470 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 1471 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
| 1472 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 1473 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 1474 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 1475 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
| 1476 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 1477 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 1478 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
D02578 D02578 💬 |
Agomelatine | 006 [1] 6 💬 |
| 1479 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
D08170 D08170 💬 |
Melatonin | 006 [12] 6 , 8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬 |
| 1480 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
D02689 D02689 💬 |
Ramelteon | 006 [3] 6 , 8 , 46 💬 |
| 1481 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
MTNR1A [2] MTNR1A, MTNR1B 💬 |
D09388 D09388 💬 |
Tasimelteon | 202 [1] 202 💬 |
| 1482 | Circadian rhythm 💬 Related to 2 target genes, 1 drug (DrugBank) and 24 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 1483 | Circadian rhythm 💬 Related to 2 target genes, 1 drug (DrugBank) and 24 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 1484 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DDC [1] DDC 💬 |
D03082 D03082 💬 |
Benserazide | 006 [1] 6 💬 |
| 1485 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
| 1486 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D11431 D11431 💬 |
Tavapadon | 006 [1] 6 💬 |
| 1487 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 1488 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 1489 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
| 1490 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 1491 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 1492 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
| 1493 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
| 1494 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
| 1495 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D00502 D00502 💬 |
Pergolide | 006 [1] 6 💬 |
| 1496 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 [2] DRD1, DRD2 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
| 1497 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 |
| 1498 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
| 1499 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
| 1500 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00702 D00702 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
| 1501 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07593 D07593 💬 |
Buspirone | 006 [3] 6 , 51, 179 💬 |
| 1502 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
| 1503 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 [1] 21 💬 |
| 1504 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1505 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1506 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1507 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 [1] 254 💬 |
| 1508 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
| 1509 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
| 1510 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00136 D00136 💬 |
Haloperidol | 008 [1] 8 💬 |
| 1511 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01898 D01898 💬 |
Haloperidol | 008 [1] 8 💬 |
| 1512 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01462 D01462 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
| 1513 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
| 1514 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07309 D07309 💬 |
Melperone | 006 [1] 6 💬 |
| 1515 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00726 D00726 💬 |
Metoclopramide | 051 [1] 51 💬 |
| 1516 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D02213 D02213 💬 |
Metoclopramide | 051 [1] 51 💬 |
| 1517 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05008 D05008 💬 |
Metoclopramide | 051 [1] 51 💬 |
| 1518 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 1519 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D06623 D06623 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
| 1520 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09397 D09397 💬 |
Pardoprunox | 006 [1] 6 💬 |
| 1521 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
| 1522 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07305 D07305 💬 |
Piribedil | 006 [1] 6 💬 |
| 1523 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00559 D00559 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
| 1524 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
| 1525 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
| 1526 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00458 D00458 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
| 1527 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08456 D08456 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
| 1528 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 |
| 1529 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00784 D00784 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
| 1530 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
| 1531 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05768 D05768 💬 |
Rotigotine | 006 [2] 6 , 127 💬 |
| 1532 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
| 1533 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08549 D08549 💬 |
Sulpiride | 002 [5] 2 , 6 , 17, 46, 70 💬 |
| 1534 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
| 1535 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08590 D08590 💬 |
Tiapride | 008 [1] 8 💬 |
| 1536 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00799 D00799 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
| 1537 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01448 D01448 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
| 1538 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08636 D08636 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
| 1539 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIA2 [1] GRIA2 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
| 1540 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIA2 [1] GRIA2 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
| 1541 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIA2 [1] GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 1542 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIA2 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
| 1543 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D02780 D02780 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 1544 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
| 1545 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00777 D00777 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 1546 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
| 1547 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00848 D00848 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 1548 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 1549 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03744 D03744 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
| 1550 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
| 1551 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00711 D00711 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 1552 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
| 1553 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
| 1554 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D04905 D04905 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 1555 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 [7] 2 , 6 , 8 , 13, 49, 127, 205 💬 |
| 1556 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
| 1557 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
| 1558 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D00505 D00505 💬 |
Phenelzine | 006 [1] 6 💬 |
| 1559 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
| 1560 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
| 1561 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOA [3] MAOA, MAOB, SLC6A3 💬 |
D05459 D05459 💬 |
Phentermine | 097 [1] 97 💬 |
| 1562 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 1563 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 1564 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 1565 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
| 1566 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D00785 D00785 💬 |
Selegiline | 006 [1] 6 💬 |
| 1567 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
| 1568 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1569 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 1570 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10701 D10701 💬 |
Deutetrabenazine | 008 [1] 8 💬 |
| 1571 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D08575 D08575 💬 |
Tetrabenazine | 008 [1] 8 💬 |
| 1572 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10675 D10675 💬 |
Valbenazine | 008 [1] 8 💬 |
| 1573 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D03215 D03215 💬 |
Armodafinil | 006 [3] 6 , 13, 84 💬 |
| 1574 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D00817 D00817 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
| 1575 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
| 1576 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D07938 D07938 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
| 1577 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D08130 D08130 💬 |
Lisdexamfetamine | 013 [1] 13 💬 |
| 1578 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D01296 D01296 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 |
| 1579 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 |
| 1580 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D08903 D08903 💬 |
Dexlansoprazole | 098 [1] 98 💬 |
| 1581 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 1582 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 1583 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 1584 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 1585 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬 |
| 1586 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 1587 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 1588 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 1589 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 1590 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D02593 D02593 💬 |
Pantoprazole | 013 [2] 13, 65 💬 |
| 1591 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 [2] 13, 65 💬 |
| 1592 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00724 D00724 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
| 1593 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
| 1594 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 [2] 63, 98 💬 |
| 1595 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 |
| 1596 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 |
| 1597 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 [1] CA2 💬 |
D00518 D00518 💬 |
Diclofenamide | 114 [1] 114 💬 |
| 1598 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 [1] CA2 💬 |
D00653 D00653 💬 |
Dorzolamide | 090 [1] 90 💬 |
| 1599 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 [1] CA2 💬 |
D07871 D07871 💬 |
Dorzolamide | 090 [1] 90 💬 |
| 1600 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 [1] CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 1601 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
| 1602 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 1603 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1604 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1605 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
| 1606 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 1607 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1608 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1609 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 1610 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 1611 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1612 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1613 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 1614 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1615 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1616 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1617 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1618 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 1619 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 1620 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
| 1621 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1622 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1623 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 1624 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C1R [3] C1R, C1S, KLKB1 💬 |
D10845 D10845 💬 |
Conestat alfa | 061 [1] 61 💬 |
| 1625 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C1S [1] C1S 💬 |
D11530 D11530 💬 |
Sutimlimab | 061 [1] 61 💬 |
| 1626 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C3 [1] C3 💬 |
D11613 D11613 💬 |
Pegcetacoplan | 002 [3] 2 , 62, 222 💬 |
| 1627 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 [1] C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 [2] 62, 109 💬 |
| 1628 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 |
| 1629 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 |
| 1630 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 [1] C5 💬 |
D11477 D11477 💬 |
Pozelimab | 011 [2] 11, 62 💬 |
| 1631 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 |
| 1632 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 [1] C5 💬 |
D11838 D11838 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 |
| 1633 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [3] 43, 44, 222 💬 |
| 1634 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
CFB [1] CFB 💬 |
D12251 D12251 💬 |
Iptacopan | 061 [5] 61, 62, 66, 109, 222 💬 |
| 1635 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
CFD [1] CFD 💬 |
D11641 D11641 💬 |
Danicopan | 062 [2] 62, 222 💬 |
| 1636 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F10 [1] F10 💬 |
D03213 D03213 💬 |
Apixaban | 096 [3] 96, 97, 222 💬 |
| 1637 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F10 [1] F10 💬 |
D09710 D09710 💬 |
Edoxaban | 046 [2] 46, 88 💬 |
| 1638 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F10 [1] F10 💬 |
D07086 D07086 💬 |
Rivaroxaban | 046 [5] 46, 49, 75, 91, 210 💬 |
| 1639 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F10 [2] F10, F9 💬 |
D10821 D10821 💬 |
Emicizumab | 288 [1] 288 💬 |
| 1640 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
| 1641 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F2 [1] F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 [1] 51 💬 |
| 1642 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F2 [1] F2 💬 |
D06410 D06410 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 |
| 1643 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F8 [1] F8 💬 |
D00291 D00291 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
| 1644 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
F8 [1] F8 💬 |
D02235 D02235 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
| 1645 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 |
| 1646 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
PLG [1] PLG 💬 |
D00160 D00160 💬 |
Aminocaproic acid | 070 [1] 70 💬 |
| 1647 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
PLG [1] PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 [6] 46, 70, 215, 227, 288, 299 💬 |
| 1648 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D03674 D03674 💬 |
Enoxaparin | 046 [1] 46 💬 |
| 1649 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D07510 D07510 💬 |
Enoxaparin | 046 [1] 46 💬 |
| 1650 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D07510 D07510 💬 |
Heparin | 047 [12] 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬 |
| 1651 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D07510 D07510 💬 |
Parnaparin | 097 [1] 97 💬 |
| 1652 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
SERPINC1 [2] SERPINC1, SERPIND1 💬 |
D08547 D08547 💬 |
Sulodexide | 013 [4] 13, 51, 271, 288 💬 |
| 1653 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
| 1654 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00620 D00620 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 |
| 1655 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D07499 D07499 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 |
| 1656 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
| 1657 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D01069 D01069 💬 |
Cilazapril | 066 [1] 66 💬 |
| 1658 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D07699 D07699 💬 |
Cilazapril | 066 [1] 66 💬 |
| 1659 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 |
| 1660 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 |
| 1661 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D08068 D08068 💬 |
Imidapril | 067 [1] 67 💬 |
| 1662 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
| 1663 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
| 1664 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00623 D00623 💬 |
Moexipril | 093 [1] 93 💬 |
| 1665 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D08225 D08225 💬 |
Moexipril | 093 [1] 93 💬 |
| 1666 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 1667 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
| 1668 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 [1] 19 💬 |
| 1669 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 [1] 19 💬 |
| 1670 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ACE [1] ACE 💬 |
D00421 D00421 💬 |
Ramipril | 046 [7] 46, 49, 66, 67, 113, 218, 257 💬 |
| 1671 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
ADAM17 [1] ADAM17 💬 |
D08859 D08859 💬 |
Apratastat | 046 [1] 46 💬 |
| 1672 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 1673 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 1674 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 1675 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 1676 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 1677 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
| 1678 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 1679 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 1680 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
| 1681 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
| 1682 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 1683 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C1R [2] C1R, C1S 💬 |
D10845 D10845 💬 |
Conestat alfa | 061 [1] 61 💬 |
| 1684 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C1S [1] C1S 💬 |
D11530 D11530 💬 |
Sutimlimab | 061 [1] 61 💬 |
| 1685 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C3 [1] C3 💬 |
D11613 D11613 💬 |
Pegcetacoplan | 002 [3] 2 , 62, 222 💬 |
| 1686 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 [1] C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 [2] 62, 109 💬 |
| 1687 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 |
| 1688 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 |
| 1689 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 [1] C5 💬 |
D11477 D11477 💬 |
Pozelimab | 011 [2] 11, 62 💬 |
| 1690 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 |
| 1691 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 [1] C5 💬 |
D11838 D11838 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 |
| 1692 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [3] 43, 44, 222 💬 |
| 1693 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
CCL2 [4] CCL2, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 1694 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
CFB [1] CFB 💬 |
D12251 D12251 💬 |
Iptacopan | 061 [5] 61, 62, 66, 109, 222 💬 |
| 1695 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
CFD [1] CFD 💬 |
D11641 D11641 💬 |
Danicopan | 062 [2] 62, 222 💬 |
| 1696 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [2] 46, 256 💬 |
| 1697 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 1698 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1699 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1700 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 1701 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 1702 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1703 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1704 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 1705 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [4] 51, 85, 91, 124 💬 |
| 1706 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
F2 [1] F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 [1] 51 💬 |
| 1707 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
F2 [1] F2 💬 |
D06410 D06410 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 |
| 1708 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
| 1709 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
| 1710 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 [2] 46, 49 💬 |
| 1711 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
| 1712 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 [1] 56 💬 |
| 1713 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 |
| 1714 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
| 1715 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 [1] 13 💬 |
| 1716 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 |
| 1717 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
| 1718 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 1719 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 1720 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 1721 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 1722 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 1723 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 1724 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
| 1725 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6R [1] IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 [2] 11, 13 💬 |
| 1726 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
| 1727 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
| 1728 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
| 1729 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
| 1730 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
| 1731 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
| 1732 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
| 1733 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 [2] JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
| 1734 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
| 1735 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
| 1736 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 |
| 1737 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1738 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 1739 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 1740 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 1741 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
SYK [1] SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 |
| 1742 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TLR7 [1] TLR7 💬 |
D02500 D02500 💬 |
Imiquimod | 034 [2] 34, 51 💬 |
| 1743 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 1744 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 1745 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 1746 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 1747 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 1748 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 1749 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
| 1750 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
| 1751 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 1752 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TYK2 [1] TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 096 [2] 96, 97 💬 |
| 1753 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
| 1754 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 1755 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 1756 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 1757 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 1758 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 1759 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
| 1760 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 1761 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 1762 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
| 1763 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
| 1764 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 1765 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1766 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1767 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1768 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 1769 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1770 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1771 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1772 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 1773 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1774 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1775 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 1776 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 1777 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1778 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1779 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 1780 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 1781 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1782 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1783 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 1784 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 1785 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
| 1786 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
| 1787 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CYP11B1 [1] CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 [2] 75, 193 💬 |
| 1788 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CYP11B1 [1] CYP11B1 💬 |
D05019 D05019 💬 |
Metyrapone | 075 [2] 75, 193 💬 |
| 1789 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CYP17A1 [1] CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 |
| 1790 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
KCNA4 [1] KCNA4 💬 |
D10228 D10228 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 |
| 1791 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
KCNA4 [1] KCNA4 💬 |
D04127 D04127 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 |
| 1792 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [15] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 |
| 1793 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00284 D00284 💬 |
Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬 |
| 1794 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
| 1795 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
| 1796 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 1797 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
| 1798 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
| 1799 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1800 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1801 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1802 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1803 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A [2] PDE8A, PDE8B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1804 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 1805 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
| 1806 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
| 1807 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 1808 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
| 1809 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
| 1810 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 1811 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
| 1812 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
| 1813 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
| 1814 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
| 1815 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 1816 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
BRAF [1] BRAF 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1817 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
BRAF [1] BRAF 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 1818 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1819 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1820 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 1821 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 1822 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1823 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1824 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 1825 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 1826 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1827 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 1828 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 1829 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 1830 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1831 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 1832 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 1833 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 1834 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1835 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 1836 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 1837 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 1838 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
| 1839 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
| 1840 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
| 1841 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CRHR1 [2] CRHR1, CRHR2 💬 |
D03905 D03905 💬 |
Corticorelin | 075 [2] 75, 205 💬 |
| 1842 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CRHR1 [2] CRHR1, CRHR2 💬 |
D03592 D03592 💬 |
Corticorelin ovine triflutate | 075 [1] 75 💬 |
| 1843 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CYP11B1 [1] CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 [2] 75, 193 💬 |
| 1844 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CYP11B1 [1] CYP11B1 💬 |
D05019 D05019 💬 |
Metyrapone | 075 [2] 75, 193 💬 |
| 1845 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CYP17A1 [1] CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 |
| 1846 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 1847 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1848 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 1849 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 1850 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 1851 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1852 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 1853 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 1854 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
KCNA4 [1] KCNA4 💬 |
D10228 D10228 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 |
| 1855 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
KCNA4 [1] KCNA4 💬 |
D04127 D04127 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 |
| 1856 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 1857 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 1858 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 1859 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 1860 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 [15] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 |
| 1861 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
MC2R [1] MC2R 💬 |
D00284 D00284 💬 |
Tetracosactide | 078 [5] 78, 83, 113, 145, 222 💬 |
| 1862 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
| 1863 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
| 1864 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 1865 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
| 1866 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
| 1867 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1868 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1869 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1870 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1871 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 1872 | Cysteine and methionine metabolism 💬 Related to 3 target genes, 1 drug (DrugBank) and 3 diseases in DDrare |
DNMT1 [3] DNMT1, DNMT3A, DNMT3B 💬 |
D03665 D03665 💬 |
Decitabine | 013 [3] 13, 60, 63 💬 |
| 1873 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
ACVR2A [1] ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 [2] 86, 284 💬 |
| 1874 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
ACVR2A [2] ACVR2A, ACVR2B 💬 |
D10620 D10620 💬 |
Bimagrumab | 015 [1] 15 💬 |
| 1875 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
BMPR2 [1] BMPR2 💬 |
D03779 D03779 💬 |
Dibotermin alfa | 034 [1] 34 💬 |
| 1876 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CCL2 [6] CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 1877 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CCR2 [2] CCR2, CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
| 1878 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CCR4 [1] CCR4 💬 |
D09761 D09761 💬 |
Mogamulizumab | 026 [1] 26 💬 |
| 1879 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
| 1880 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
| 1881 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
| 1882 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
| 1883 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
| 1884 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF1 [1] CSF1 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 1885 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF1 [1] CSF1 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 1886 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF1R [1] CSF1R 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
| 1887 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [2] 46, 256 💬 |
| 1888 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF2RA [1] CSF2RA 💬 |
D09930 D09930 💬 |
Mavrilimumab | 041 [2] 41, 46 💬 |
| 1889 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF2RA [1] CSF2RA 💬 |
D05066 D05066 💬 |
Molgramostim | 097 [3] 97, 229, 299 💬 |
| 1890 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF2RA [1] CSF2RA 💬 |
D05712 D05712 💬 |
Regramostim | 229 [1] 229 💬 |
| 1891 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF2RA [1] CSF2RA 💬 |
D05803 D05803 💬 |
Sargramostim | 006 [7] 6 , 28, 60, 62, 96, 229, 285 💬 |
| 1892 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF3R [1] CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 [34] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
| 1893 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF3R [1] CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 |
| 1894 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CSF3R [1] CSF3R 💬 |
D06889 D06889 💬 |
Pegfilgrastim | 060 [1] 60 💬 |
| 1895 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
| 1896 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [6] 19, 20, 51, 65, 285, 299 💬 |
| 1897 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
EPOR [1] EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 [10] 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
| 1898 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
EPOR [1] EPOR 💬 |
D09946 D09946 💬 |
Peginesatide | 283 [1] 283 💬 |
| 1899 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D11486 D11486 💬 |
Lonapegsomatropin | 078 [1] 78 💬 |
| 1900 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 1901 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 1902 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D05394 D05394 💬 |
Pegvisomant | 078 [1] 78 💬 |
| 1903 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D11194 D11194 💬 |
Somapacitan | 078 [1] 78 💬 |
| 1904 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 [23] 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
| 1905 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR [1] GHR 💬 |
D11193 D11193 💬 |
Somavaratan | 078 [1] 78 💬 |
| 1906 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
| 1907 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
| 1908 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 [2] 46, 49 💬 |
| 1909 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
| 1910 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 [1] 56 💬 |
| 1911 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 |
| 1912 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
| 1913 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 [1] 13 💬 |
| 1914 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 |
| 1915 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
| 1916 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
| 1917 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IFNGR1 [2] IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 [7] 18, 65, 85, 228, 299, 301, 326 💬 |
| 1918 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL11RA [1] IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 [2] 96, 288 💬 |
| 1919 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL12A [3] IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
| 1920 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL13 [1] IL13 💬 |
D08857 D08857 💬 |
Anrukinzumab | 097 [1] 97 💬 |
| 1921 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL13 [1] IL13 💬 |
D09633 D09633 💬 |
Lebrikizumab | 085 [1] 85 💬 |
| 1922 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL13 [1] IL13 💬 |
D09979 D09979 💬 |
Tralokinumab | 085 [2] 85, 97 💬 |
| 1923 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [6] 36, 37, 107, 162, 269, 271 💬 |
| 1924 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
| 1925 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [2] IL17A, IL17F 💬 |
D11550 D11550 💬 |
Bimekizumab | 046 [3] 46, 97, 271 💬 |
| 1926 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17A [2] IL17A, TNFSF13B 💬 |
D11127 D11127 💬 |
Tibulizumab | 053 [1] 53 💬 |
| 1927 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17RA [1] IL17RA 💬 |
D10061 D10061 💬 |
Brodalumab | 037 [2] 37, 51 💬 |
| 1928 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
| 1929 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 1930 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 1931 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 1932 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1R1 [2] IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
| 1933 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL1RL2 [1] IL1RL2 💬 |
D12066 D12066 💬 |
Spesolimab | 037 [3] 37, 96, 97 💬 |
| 1934 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL20 [1] IL20 💬 |
D11756 D11756 💬 |
Fletikumab | 046 [1] 46 💬 |
| 1935 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL22 [1] IL22 💬 |
D11953 D11953 💬 |
Efmarodocokin alfa | 096 [2] 96, 97 💬 |
| 1936 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
| 1937 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 |
| 1938 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
| 1939 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
| 1940 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10400 D10400 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 |
| 1941 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 |
| 1942 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
| 1943 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
| 1944 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL31RA [1] IL31RA 💬 |
D11080 D11080 💬 |
Nemolizumab | 051 [1] 51 💬 |
| 1945 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL4 [1] IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 [1] 46 💬 |
| 1946 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL4R [1] IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 [4] 51, 98, 160, 162 💬 |
| 1947 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL5 [1] IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 [4] 44, 45, 98, 162 💬 |
| 1948 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL5 [1] IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 [2] 44, 98 💬 |
| 1949 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL5RA [1] IL5RA 💬 |
D09874 D09874 💬 |
Benralizumab | 044 [5] 44, 45, 98, 162, 299 💬 |
| 1950 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 1951 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 1952 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 1953 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
| 1954 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 [2] 11, 13 💬 |
| 1955 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
| 1956 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
LEPR [1] LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 [1] 265 💬 |
| 1957 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
LTA [1] LTA 💬 |
D10187 D10187 💬 |
Pateclizumab | 046 [1] 46 💬 |
| 1958 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 1959 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
LTB [1] LTB 💬 |
D08866 D08866 💬 |
Baminercept | 013 [4] 13, 46, 53, 97 💬 |
| 1960 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
MPL [1] MPL 💬 |
D10306 D10306 💬 |
Avatrombopag | 060 [2] 60, 63 💬 |
| 1961 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
MPL [1] MPL 💬 |
D08990 D08990 💬 |
Romiplostim | 060 [4] 60, 63, 64, 65 💬 |
| 1962 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
MSTN [1] MSTN 💬 |
D11797 D11797 💬 |
Apitegromab | 003 [1] 3 💬 |
| 1963 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
MSTN [1] MSTN 💬 |
D11047 D11047 💬 |
Domagrozumab | 113 [1] 113 💬 |
| 1964 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
| 1965 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
NGFR [1] NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 [2] 53, 90 💬 |
| 1966 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
PRL [1] PRL 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
| 1967 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
PRL [1] PRL 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
| 1968 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
PRL [1] PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
| 1969 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
PRL [1] PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
| 1970 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 1971 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 1972 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 1973 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 1974 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 1975 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 1976 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
| 1977 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
| 1978 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 1979 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFRSF13C [1] TNFRSF13C 💬 |
D12151 D12151 💬 |
Ianalumab | 035 [5] 35, 46, 49, 53, 95 💬 |
| 1980 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFRSF17 [1] TNFRSF17 💬 |
D11595 D11595 💬 |
Belantamab mafodotin | 028 [1] 28 💬 |
| 1981 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFRSF8 [1] TNFRSF8 💬 |
D09587 D09587 💬 |
Brentuximab vedotin | 049 [2] 49, 51 💬 |
| 1982 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [7] 46, 50, 93, 95, 96, 274, 299 💬 |
| 1983 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFSF13 [2] TNFSF13, TNFSF13B 💬 |
D09704 D09704 💬 |
Atacicept | 013 [4] 13, 46, 49, 66 💬 |
| 1984 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D03068 D03068 💬 |
Belimumab | 011 [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬 |
| 1985 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D10083 D10083 💬 |
Tabalumab | 046 [2] 46, 49 💬 |
| 1986 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
| 1987 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
| 1988 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 1989 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 1990 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 1991 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL1B [2] IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 1992 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL6 [1] IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 1993 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 1994 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 1995 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 1996 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 11 drugs (DrugBank) and 26 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |