Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 ECM-receptor interaction 💬
 [1] ITGA4 💬 D06590 💬 Firategrast [1] 13 💬
2 ECM-receptor interaction 💬
 [1] ITGA4 💬 D06886 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
3 ECM-receptor interaction 💬
 [2] ITGA4, ITGB7 💬 D10540 💬 Abrilumab [2] 96, 97 💬
4 ECM-receptor interaction 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
5 ECM-receptor interaction 💬
 [1] ITGB7 💬 D09901 💬 Etrolizumab [2] 96, 97 💬
6 ECM-receptor interaction 💬
 [1] SV2A 💬 D08879 💬 Brivaracetam [2] 149, 309 💬
7 ECM-receptor interaction 💬
 [1] SV2A 💬 D00709 💬 Levetiracetam [5]  2 ,  4 ,  6 , 13, 307 💬
8 ECM-receptor interaction 💬
 [3] SV2A, SV2B, SV2C 💬 D11842 💬 Padsevonil [1] 149 💬
9 ECM-receptor interaction 💬
 [1] VWF 💬 D11160 💬 Caplacizumab [1] 64 💬
10 EGFR tyrosine kinase inhibitor resistance 💬
 [3] AXL, KDR, MET 💬 D10062 💬 Cabozantinib [1] 34 💬
11 EGFR tyrosine kinase inhibitor resistance 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
12 EGFR tyrosine kinase inhibitor resistance 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
13 EGFR tyrosine kinase inhibitor resistance 💬
 [4] BRAF, KDR, PDGFRB, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
14 EGFR tyrosine kinase inhibitor resistance 💬
 [4] BRAF, KDR, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
15 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
16 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
17 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
18 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
19 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
20 EGFR tyrosine kinase inhibitor resistance 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
21 EGFR tyrosine kinase inhibitor resistance 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
22 EGFR tyrosine kinase inhibitor resistance 💬
 [3] EGFR, ERBB2, KDR 💬 D11772 💬 Tesevatinib [1] 67 💬
23 EGFR tyrosine kinase inhibitor resistance 💬
 [1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
24 EGFR tyrosine kinase inhibitor resistance 💬
 [2] FGFR2, FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
25 EGFR tyrosine kinase inhibitor resistance 💬
 [5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
26 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
27 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
28 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
29 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
30 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
31 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
32 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
33 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
34 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
35 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [2] 11, 13 💬
36 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
37 EGFR tyrosine kinase inhibitor resistance 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
38 EGFR tyrosine kinase inhibitor resistance 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
39 EGFR tyrosine kinase inhibitor resistance 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
40 EGFR tyrosine kinase inhibitor resistance 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
41 EGFR tyrosine kinase inhibitor resistance 💬
 [2] JAK1, JAK2 💬 D10653 💬 Peficitinib [1] 46 💬
42 EGFR tyrosine kinase inhibitor resistance 💬
 [2] JAK1, JAK2 💬 D09959 💬 Ruxolitinib [1] 228 💬
43 EGFR tyrosine kinase inhibitor resistance 💬
 [2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
44 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 D03218 💬 Axitinib [1] 34 💬
45 EGFR tyrosine kinase inhibitor resistance 💬
 [1] KDR 💬 D08881 💬 Cediranib [1] 34 💬
46 EGFR tyrosine kinase inhibitor resistance 💬
 [3] KDR, PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib [2] 28, 34 💬
47 EGFR tyrosine kinase inhibitor resistance 💬
 [3] KDR, PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib [2] 28, 34 💬
48 EGFR tyrosine kinase inhibitor resistance 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
49 EGFR tyrosine kinase inhibitor resistance 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
50 EGFR tyrosine kinase inhibitor resistance 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
51 EGFR tyrosine kinase inhibitor resistance 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
52 EGFR tyrosine kinase inhibitor resistance 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
53 EGFR tyrosine kinase inhibitor resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
54 EGFR tyrosine kinase inhibitor resistance 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
55 EGFR tyrosine kinase inhibitor resistance 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
56 EGFR tyrosine kinase inhibitor resistance 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
57 EGFR tyrosine kinase inhibitor resistance 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
58 EGFR tyrosine kinase inhibitor resistance 💬
 [2] PDGFRB, SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
59 EGFR tyrosine kinase inhibitor resistance 💬
 [2] PDGFRB, SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
60 EGFR tyrosine kinase inhibitor resistance 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
61 EGFR tyrosine kinase inhibitor resistance 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
62 EGFR tyrosine kinase inhibitor resistance 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
63 EGFR tyrosine kinase inhibitor resistance 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
64 EGFR tyrosine kinase inhibitor resistance 💬
 [1] VEGFA 💬 D09574 💬 Aflibercept [2] 90, 166 💬
65 EGFR tyrosine kinase inhibitor resistance 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
66 EGFR tyrosine kinase inhibitor resistance 💬
 [1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬
67 Endocrine and other factor-regulated calcium reabsorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin [1] 299 💬
68 Endocrine and other factor-regulated calcium reabsorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
69 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00962 💬 Clomifene [1] 74 💬
70 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D07726 💬 Clomifene [1] 74 💬
71 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
72 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
73 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D11513 💬 Estetrol [1] 53 💬
74 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D11514 💬 Estetrol [1] 53 💬
75 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
76 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
77 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
78 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
79 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
80 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
81 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
82 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
83 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01413 💬 Estradiol valerate [1] 65 💬
84 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00185 💬 Estriol [2] 13, 227 💬
85 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01986 💬 Estriol [2] 13, 227 💬
86 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00554 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
87 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
88 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00575 💬 Mestranol [2] 46, 49 💬
89 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
90 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D02217 💬 Raloxifene [1] 46 💬
91 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D08465 💬 Raloxifene [1] 46 💬
92 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D00966 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
93 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D08559 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
94 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] PTH1R 💬 D05364 💬 Parathyroid hormone [4] 65, 70, 235, 326 💬
95 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] PTH1R 💬 D06078 💬 Teriparatide [7] 46, 65, 68, 70, 71, 235, 274 💬
96 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
97 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00122 💬 Calcifediol [2] 113, 299 💬
98 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D01125 💬 Calcipotriol [2] 36, 51 💬
99 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
100 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
101 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00299 💬 Dihydrotachysterol [2]  6 , 85 💬
102 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D07578 💬 Eldecalcitol [1] 46 💬
103 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00187 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
104 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00930 💬 Paricalcitol [4] 19, 66, 218, 238 💬
105 Endocrine resistance 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
106 Endocrine resistance 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
107 Endocrine resistance 💬
 [2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
108 Endocrine resistance 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
109 Endocrine resistance 💬
 [1] CDK4 💬 D10688 💬 Abemaciclib [1] 34 💬
110 Endocrine resistance 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
111 Endocrine resistance 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
112 Endocrine resistance 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
113 Endocrine resistance 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
114 Endocrine resistance 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
115 Endocrine resistance 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
116 Endocrine resistance 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
117 Endocrine resistance 💬
 [2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
118 Endocrine resistance 💬
 [1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
119 Endocrine resistance 💬
 [1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
120 Endocrine resistance 💬
 [1] ESR1 💬 D00554 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
121 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D00962 💬 Clomifene [1] 74 💬
122 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D07726 💬 Clomifene [1] 74 💬
123 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
124 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
125 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
126 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
127 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
128 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
129 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
130 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
131 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
132 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
133 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol valerate [1] 65 💬
134 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D00185 💬 Estriol [2] 13, 227 💬
135 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01986 💬 Estriol [2] 13, 227 💬
136 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
137 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D00575 💬 Mestranol [2] 46, 49 💬
138 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
139 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D02217 💬 Raloxifene [1] 46 💬
140 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D08465 💬 Raloxifene [1] 46 💬
141 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D00966 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
142 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D08559 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
143 Endocrine resistance 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
144 Endocrine resistance 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
145 Endocrine resistance 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
146 Endocrine resistance 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
147 Endocrine resistance 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
148 Endocrine resistance 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
149 Endocrine resistance 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
150 Endocrine resistance 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
151 Endocrine resistance 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
152 Endocrine resistance 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
153 Endocrine resistance 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
154 Endocrine resistance 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
155 Endocrine resistance 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
156 Endocrine resistance 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
157 Endocrine resistance 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
158 Endocrine resistance 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
159 Endocrine resistance 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
160 Endocrine resistance 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
161 Endocrine resistance 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
162 Endocytosis 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
163 Endocytosis 💬
 [1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
164 Endocytosis 💬
 [2] CXCR1, CXCR2 💬 D08984 💬 Reparixin [2] 298, 299 💬
165 Endocytosis 💬
 [1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
166 Endocytosis 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
167 Endocytosis 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
168 Endocytosis 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
169 Endocytosis 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
170 Endocytosis 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
171 Endocytosis 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
172 Endocytosis 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
173 Endocytosis 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
174 Endocytosis 💬
 [1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
175 Endocytosis 💬
 [2] FGFR2, FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
176 Endocytosis 💬
 [3] FGFR2, FGFR3, PDGFRA 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
177 Endocytosis 💬
 [6] HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer [4]  2 , 13, 96, 156 💬
178 Endocytosis 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
179 Endocytosis 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
180 Endocytosis 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
181 Endocytosis 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
182 Endocytosis 💬
 [1] IL2RA 💬 D03058 💬 Basiliximab [6]  2 , 50, 66, 97, 222, 228 💬
183 Endocytosis 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
184 Endocytosis 💬
 [3] IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
185 Endocytosis 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
186 Endocytosis 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
187 Endocytosis 💬
 [1] PDGFRA 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
188 Endocytosis 💬
 [1] PDGFRA 💬 D06402 💬 Sunitinib [2] 28, 34 💬
189 Endocytosis 💬
 [1] PDGFRA 💬 D08552 💬 Sunitinib [2] 28, 34 💬
190 Endocytosis 💬
 [1] PML 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
191 Endocytosis 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
192 Endocytosis 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
193 Endocytosis 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
194 Endocytosis 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
195 Endocytosis 💬
 [1] TFRC 💬 D11812 💬 Pabinafusp alfa [1] 19 💬
196 Endometrial cancer 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
197 Endometrial cancer 💬
 [2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
198 Endometrial cancer 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
199 Endometrial cancer 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
200 Endometrial cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
201 Endometrial cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
202 Endometrial cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
203 Endometrial cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
204 Endometrial cancer 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
205 Endometrial cancer 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
206 Endometrial cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
207 Endometrial cancer 💬
 [2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
208 Endometrial cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
209 Endometrial cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
210 Endometrial cancer 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
211 Endometrial cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
212 Endometrial cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
213 Endometrial cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
214 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] ADAM17 💬 D08859 💬 Apratastat [1] 46 💬
215 Epithelial cell signaling in Helicobacter pylori infection 💬
 [2] CXCR1, CXCR2 💬 D08984 💬 Reparixin [2] 298, 299 💬
216 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
217 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
218 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
219 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
220 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
221 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
222 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
223 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
224 Epithelial cell signaling in Helicobacter pylori infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
225 Epithelial cell signaling in Helicobacter pylori infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
226 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
227 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
228 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
229 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
230 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
231 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
232 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
233 Epstein-Barr virus infection 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
234 Epstein-Barr virus infection 💬
 [1] BTK 💬 D10893 💬 Acalabrutinib [2] 46, 61 💬
235 Epstein-Barr virus infection 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
236 Epstein-Barr virus infection 💬
 [1] BTK 💬 D11457 💬 Fenebrutinib [1] 13 💬
237 Epstein-Barr virus infection 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
238 Epstein-Barr virus infection 💬
 [1] BTK 💬 D12160 💬 Orelabrutinib [3] 13, 61, 63 💬
239 Epstein-Barr virus infection 💬
 [1] BTK 💬 D11422 💬 Zanubrutinib [2] 300, 331 💬
240 Epstein-Barr virus infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
241 Epstein-Barr virus infection 💬
 [1] CD19 💬 D11757 💬 Inebilizumab [4] 11, 13, 51, 300 💬
242 Epstein-Barr virus infection 💬
 [3] CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab [3] 60, 96, 97 💬
243 Epstein-Barr virus infection 💬
 [3] CD3D, CD3E, CD3G 💬 D08959 💬 Otelixizumab [1] 46 💬
244 Epstein-Barr virus infection 💬
 [3] CD3D, CD3E, CD3G 💬 D06314 💬 Visilizumab [2] 96, 97 💬
245 Epstein-Barr virus infection 💬
 [1] CD3E 💬 D11463 💬 Mosunetuzumab [1] 49 💬
246 Epstein-Barr virus infection 💬
 [1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
247 Epstein-Barr virus infection 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
248 Epstein-Barr virus infection 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
249 Epstein-Barr virus infection 💬
 [1] CD58 💬 D02800 💬 Alefacept [6] 37, 60, 65, 164, 284, 285 💬
250 Epstein-Barr virus infection 💬
 [2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
251 Epstein-Barr virus infection 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
252 Epstein-Barr virus infection 💬
 [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer [4]  2 , 13, 96, 156 💬
253 Epstein-Barr virus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
254 Epstein-Barr virus infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
255 Epstein-Barr virus infection 💬
 [2] IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab [2] 46, 49 💬
256 Epstein-Barr virus infection 💬
 [2] IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
257 Epstein-Barr virus infection 💬
 [2] IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a [1] 56 💬
258 Epstein-Barr virus infection 💬
 [2] IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b [2] 25, 34 💬
259 Epstein-Barr virus infection 💬
 [2] IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
260 Epstein-Barr virus infection 💬
 [2] IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b [1] 13 💬
261 Epstein-Barr virus infection 💬
 [2] IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a [1] 13 💬
262 Epstein-Barr virus infection 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
263 Epstein-Barr virus infection 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
264 Epstein-Barr virus infection 💬
 [2] IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
265 Epstein-Barr virus infection 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
266 Epstein-Barr virus infection 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
267 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
268 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
269 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
270 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D09959 💬 Ruxolitinib [1] 228 💬
271 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
272 Epstein-Barr virus infection 💬
 [2] JAK1, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
273 Epstein-Barr virus infection 💬
 [3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
274 Epstein-Barr virus infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
275 Epstein-Barr virus infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
276 Epstein-Barr virus infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
277 Epstein-Barr virus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
278 Epstein-Barr virus infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
279 Epstein-Barr virus infection 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
280 Epstein-Barr virus infection 💬
 [1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
281 Epstein-Barr virus infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
282 Epstein-Barr virus infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
283 Epstein-Barr virus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
284 Epstein-Barr virus infection 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
285 Epstein-Barr virus infection 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
286 Epstein-Barr virus infection 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
287 Epstein-Barr virus infection 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
288 Epstein-Barr virus infection 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
289 Epstein-Barr virus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
290 Epstein-Barr virus infection 💬
 [1] TYK2 💬 D11817 💬 Deucravacitinib [2] 96, 97 💬
291 ErbB signaling pathway 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
292 ErbB signaling pathway 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
293 ErbB signaling pathway 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
294 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
295 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
296 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
297 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
298 ErbB signaling pathway 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
299 ErbB signaling pathway 💬
 [2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
300 ErbB signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
301 ErbB signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
302 ErbB signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
303 ErbB signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
304 ErbB signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
305 ErbB signaling pathway 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
306 ErbB signaling pathway 💬
 [2] EGFR, ERBB2 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
307 ErbB signaling pathway 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
308 ErbB signaling pathway 💬
 [2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
309 ErbB signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
310 ErbB signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
311 ErbB signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
312 ErbB signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
313 ErbB signaling pathway 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
314 ErbB signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
315 ErbB signaling pathway 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
316 ErbB signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
317 ErbB signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
318 Estrogen signaling pathway 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
319 Estrogen signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
320 Estrogen signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
321 Estrogen signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
322 Estrogen signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
323 Estrogen signaling pathway 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
324 Estrogen signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
325 Estrogen signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
326 Estrogen signaling pathway 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
327 Estrogen signaling pathway 💬
 [1] ESR1 💬 D00554 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
328 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D00962 💬 Clomifene [1] 74 💬
329 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D07726 💬 Clomifene [1] 74 💬
330 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
331 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
332 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
333 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
334 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
335 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
336 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
337 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
338 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
339 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
340 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01413 💬 Estradiol valerate [1] 65 💬
341 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D00185 💬 Estriol [2] 13, 227 💬
342 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01986 💬 Estriol [2] 13, 227 💬
343 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
344 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D00575 💬 Mestranol [2] 46, 49 💬
345 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
346 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D02217 💬 Raloxifene [1] 46 💬
347 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D08465 💬 Raloxifene [1] 46 💬
348 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D00966 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
349 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D08559 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
350 Estrogen signaling pathway 💬
 [2] ESR1, PGR 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
351 Estrogen signaling pathway 💬
 [2] ESR1, PGR 💬 D02367 💬 Desogestrel [1] 230 💬
352 Estrogen signaling pathway 💬
 [2] GABBR1, GABBR2 💬 D09791 💬 Arbaclofen [2] 13, 206 💬
353 Estrogen signaling pathway 💬
 [2] GABBR1, GABBR2 💬 D08861 💬 Arbaclofen Placarbil [1] 13 💬
354 Estrogen signaling pathway 💬
 [2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
355 Estrogen signaling pathway 💬
 [2] KCNJ3, KCNJ5 💬 D00636 💬 Amiodarone [2] 28, 127 💬
356 Estrogen signaling pathway 💬
 [2] KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
357 Estrogen signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
358 Estrogen signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
359 Estrogen signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
360 Estrogen signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
361 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D00836 💬 Buprenorphine [3] 46, 70, 298 💬
362 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D07132 💬 Buprenorphine [3] 46, 70, 298 💬
363 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01481 💬 Dihydrocodeine [1] 310 💬
364 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D07831 💬 Dihydrocodeine [1] 310 💬
365 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D00320 💬 Fentanyl [4] 46, 70, 215, 231 💬
366 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01399 💬 Fentanyl [4] 46, 70, 215, 231 💬
367 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D00839 💬 Hydromorphone [1] 70 💬
368 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08047 💬 Hydromorphone [1] 70 💬
369 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D00729 💬 Loperamide [2] 13, 97 💬
370 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D07113 💬 Loperamide [2] 13, 97 💬
371 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08144 💬 Loperamide [2] 13, 97 💬
372 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01383 💬 Meperidine [1] 298 💬
373 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08343 💬 Meperidine [1] 298 💬
374 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D00842 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
375 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D02271 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
376 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08233 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
377 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D00843 💬 Nalbuphine [1] 85 💬
378 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08246 💬 Nalbuphine [1] 85 💬
379 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05111 💬 Nalmefene [1]  6  💬
380 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01340 💬 Naloxone [2]  6 , 226 💬
381 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08249 💬 Naloxone [2]  6 , 226 💬
382 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
383 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
384 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D03783 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
385 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05312 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
386 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05462 💬 Oxycodone [7]  6 , 13, 46, 70, 226, 231, 298 💬
387 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08323 💬 Oxymorphone [1] 70 💬
388 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01177 💬 Remifentanil [2]  6 , 70 💬
389 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08473 💬 Remifentanil [2]  6 , 70 💬
390 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D00845 💬 Sufentanil [2] 70, 280 💬
391 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D05938 💬 Sufentanil [2] 70, 280 💬
392 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D01355 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
393 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08623 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
394 Estrogen signaling pathway 💬
 [1] OPRM1 💬 D08639 💬 Trimebutine [1] 51 💬
395 Estrogen signaling pathway 💬
 [1] PGR 💬 D01217 💬 Dydrogesterone [1] 13 💬
396 Estrogen signaling pathway 💬
 [1] PGR 💬 D00950 💬 Levonorgestrel [1] 13 💬
397 Estrogen signaling pathway 💬
 [1] PGR 💬 D00951 💬 Medroxyprogesterone acetate [6] 13, 35, 46, 49, 51, 60 💬
398 Estrogen signaling pathway 💬
 [1] PGR 💬 D08166 💬 Medroxyprogesterone acetate [6] 13, 35, 46, 49, 51, 60 💬
399 Estrogen signaling pathway 💬
 [1] PGR 💬 D00952 💬 Megestrol acetate [1] 76 💬
400 Estrogen signaling pathway 💬
 [1] PGR 💬 D08167 💬 Megestrol acetate [1] 76 💬
401 Estrogen signaling pathway 💬
 [1] PGR 💬 D00585 💬 Mifepristone [1] 75 💬
402 Estrogen signaling pathway 💬
 [1] PGR 💬 D07222 💬 Nomegestrol [1] 13 💬
403 Estrogen signaling pathway 💬
 [1] PGR 💬 D08281 💬 Nomegestrol acetate [1] 13 💬
404 Estrogen signaling pathway 💬
 [1] PGR 💬 D00182 💬 Norethisterone [4] 13, 46, 49, 299 💬
405 Estrogen signaling pathway 💬
 [1] PGR 💬 D00953 💬 Norethisterone [4] 13, 46, 49, 299 💬
406 Estrogen signaling pathway 💬
 [1] PGR 💬 D05209 💬 Norgestimate [1] 299 💬
407 Estrogen signaling pathway 💬
 [1] PGR 💬 D00066 💬 Progesterone [1] 76 💬
408 Estrogen signaling pathway 💬
 [1] PGR 💬 D09567 💬 Ulipristal [1] 10 💬
409 Estrogen signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
410 Estrogen signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
411 Estrogen signaling pathway 💬
 [1] PRKCD 💬 D09671 💬 Sotrastaurin [1] 97 💬
412 Estrogen signaling pathway 💬
 [1] RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
413 Estrogen signaling pathway 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
414 Estrogen signaling pathway 💬
 [1] RARA 💬 D02754 💬 Acitretin [1] 37 💬
415 Estrogen signaling pathway 💬
 [1] RARA 💬 D02815 💬 Alitretinoin [1] 49 💬
416 Estrogen signaling pathway 💬
 [1] RARA 💬 D04162 💬 Fenretinide [1] 299 💬
417 Estrogen signaling pathway 💬
 [1] RARA 💬 D00348 💬 Isotretinoin [4] 36, 39, 159, 160 💬
418 Estrogen signaling pathway 💬
 [1] RARA 💬 D01418 💬 Tamibarotene [2] 26, 96 💬
419 Estrogen signaling pathway 💬
 [1] RARA 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
420 Estrogen signaling pathway 💬
 [1] RARA 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
421 Estrogen signaling pathway 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
422 Estrogen signaling pathway 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
423 Estrogen signaling pathway 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
424 Estrogen signaling pathway 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
425 Ether lipid metabolism 💬
 [1] ENPP2 💬 D11844 💬 Ziritaxestat [2] 51, 85 💬

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