Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
CCL2 [5] CCL2, IL10, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 2 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
| 3 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
| 4 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
| 5 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
| 6 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [2] 49, 107 💬 |
| 7 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
| 8 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL12A [1] IL12A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
| 9 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 10 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 11 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL1B [1] IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 12 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 13 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 14 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 15 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
| 16 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
| 17 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 18 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 19 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 20 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 21 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 22 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 23 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 24 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
| 25 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
| 26 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 27 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 28 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 29 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 30 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 31 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 32 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 33 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
| 34 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 35 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 36 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
| 37 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
| 38 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 39 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
| 40 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
| 41 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
| 42 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 43 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
| 44 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
| 45 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 46 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 47 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 [3] 96, 140, 167 💬 |
| 48 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 49 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 [4] 58, 86, 149, 215 💬 |
| 50 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
| 51 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 [1] 6 💬 |
| 52 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA2D1 [2] CACNA2D1, CACNA2D2 💬 |
D11203 D11203 💬 |
Mirogabalin | 070 [1] 70 💬 |
| 53 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
| 54 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
| 55 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CSF1 [8] CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 56 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CSF1 [8] CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 57 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CSF1R [3] CSF1R, FLT3, KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
| 58 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 59 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 60 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 61 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 62 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 63 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 64 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 65 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 66 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 67 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
EPHA2 [3] EPHA2, KIT, PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 68 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
FGF23 [1] FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 [1] 238 💬 |
| 69 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
| 70 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
| 71 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
| 72 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
| 73 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
| 74 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
| 75 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 76 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 77 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
| 78 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
| 79 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 80 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1A [3] IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 81 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 82 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 83 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
IL1R1 [1] IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 [19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
| 84 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
| 85 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
| 86 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
| 87 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
| 88 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
KDR [2] KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
| 89 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
| 90 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
KIT [2] KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 91 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 92 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 93 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 94 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 95 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 96 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 97 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAP3K5 [1] MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 [1] 86 💬 |
| 98 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
| 99 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
| 100 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAPT [1] MAPT 💬 |
D11210 D11210 💬 |
Flortaucipir | 005 [3] 5 , 7 , 127 💬 |
| 101 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAPT [1] MAPT 💬 |
D11293 D11293 💬 |
Gosuranemab | 005 [1] 5 💬 |
| 102 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 103 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
| 104 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
NGFR [1] NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 [2] 53, 90 💬 |
| 105 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PGF [3] PGF, VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
| 106 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 107 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
| 108 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 109 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 110 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 [1] 222 💬 |
| 111 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 112 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 113 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 114 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 115 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 116 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 117 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 118 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 119 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
| 120 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
| 121 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 122 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 123 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 124 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
| 125 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
| 126 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
| 127 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 [3] 60, 96, 97 💬 |
| 128 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 [1] 46 💬 |
| 129 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
| 130 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
CD3E [1] CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 [1] 49 💬 |
| 131 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
| 132 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
| 133 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
| 134 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 [2] 46, 49 💬 |
| 135 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
| 136 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 [1] 56 💬 |
| 137 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 |
| 138 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
| 139 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 [1] 13 💬 |
| 140 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 |
| 141 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
| 142 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
| 143 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
| 144 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1A [3] IL1A, IL1B, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 145 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 146 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
| 147 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 |
| 148 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
| 149 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
| 150 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL6 [1] IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 151 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
| 152 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
| 153 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
| 154 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
| 155 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [5] 46, 51, 60, 97, 228 💬 |
| 156 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 [1] 228 💬 |
| 157 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
| 158 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [2] JAK1, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
| 159 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 [3] JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
| 160 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 161 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 162 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 163 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 164 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
TLR7 [1] TLR7 💬 |
D02500 D02500 💬 |
Imiquimod | 034 [2] 34, 51 💬 |
| 165 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
TYK2 [1] TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 096 [2] 96, 97 💬 |
| 166 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
EDNRB [1] EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 167 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
EDNRB [1] EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
| 168 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
EDNRB [1] EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
| 169 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 170 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 171 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 172 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 173 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
| 174 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 175 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
| 176 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 177 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [1] KIT 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 178 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [2] KIT, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 179 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
KIT [2] KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 180 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 181 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 182 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 183 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 184 | Melanogenesis 💬 Related to 6 target genes, 14 drugs (DrugBank) and 28 diseases in DDrare |
MC1R [1] MC1R 💬 |
D10511 D10511 💬 |
Afamelanotide | 159 [3] 159, 161, 254 💬 |
| 185 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 186 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 187 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 188 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
| 189 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 190 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 191 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 192 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 193 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 194 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 195 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 196 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 197 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
FGF23 [1] FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 [1] 238 💬 |
| 198 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
FGFR1 [1] FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
| 199 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
FGFR1 [3] FGFR1, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
| 200 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
| 201 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 202 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 203 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
| 204 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 205 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 206 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 207 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 208 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
| 209 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 210 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 211 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 212 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 213 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 214 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 215 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRB [1] PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 216 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 217 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 218 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ABAT [1] ABAT 💬 |
D00535 D00535 💬 |
Vigabatrin | 145 [2] 145, 158 💬 |
| 219 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
| 220 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ADA [1] ADA 💬 |
D11017 D11017 💬 |
Elapegademase | 065 [1] 65 💬 |
| 221 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 [1] 301 💬 |
| 222 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ALAS1 [1] ALAS1 💬 |
D11702 D11702 💬 |
Givosiran | 254 [1] 254 💬 |
| 223 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ALAS1 [2] ALAS1, ALAS2 💬 |
D10003 D10003 💬 |
Hemin | 254 [1] 254 💬 |
| 224 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D01773 D01773 💬 |
Oxatomide | 113 [1] 113 💬 |
| 225 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ALOX5 [1] ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 |
| 226 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ALPL [1] ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 [1] 172 💬 |
| 227 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
AMY2A [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
| 228 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ANPEP [1] ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 [1] 86 💬 |
| 229 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
AOC3 [1] AOC3 💬 |
D08044 D08044 💬 |
Hydralazine | 067 [1] 67 💬 |
| 230 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ARSB [1] ARSB 💬 |
D06565 D06565 💬 |
Galsulfase | 019 [1] 19 💬 |
| 231 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D08903 D08903 💬 |
Dexlansoprazole | 098 [1] 98 💬 |
| 232 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01984 D01984 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 233 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D04056 D04056 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 234 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 235 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D09339 D09339 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 236 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬 |
| 237 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 238 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D01207 D01207 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 239 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D05259 D05259 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 240 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D05261 D05261 💬 |
Omeprazole | 006 [16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 |
| 241 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D02593 D02593 💬 |
Pantoprazole | 013 [2] 13, 65 💬 |
| 242 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 [2] 13, 65 💬 |
| 243 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00724 D00724 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
| 244 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 |
| 245 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 [2] 63, 98 💬 |
| 246 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 |
| 247 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 |
| 248 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00518 D00518 💬 |
Diclofenamide | 114 [1] 114 💬 |
| 249 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00653 D00653 💬 |
Dorzolamide | 090 [1] 90 💬 |
| 250 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D07871 D07871 💬 |
Dorzolamide | 090 [1] 90 💬 |
| 251 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA2 [2] CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 252 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CD38 [1] CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 [5] 16, 28, 49, 63, 222 💬 |
| 253 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CD38 [1] CD38 💬 |
D11050 D11050 💬 |
Isatuximab | 028 [2] 28, 61 💬 |
| 254 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CD38 [1] CD38 💬 |
D11945 D11945 💬 |
Mezagitamab | 066 [1] 66 💬 |
| 255 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
COMT [1] COMT 💬 |
D00781 D00781 💬 |
Entacapone | 006 [2] 6 , 17 💬 |
| 256 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
COMT [1] COMT 💬 |
D10825 D10825 💬 |
Opicapone | 006 [1] 6 💬 |
| 257 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
COMT [1] COMT 💬 |
D00786 D00786 💬 |
Tolcapone | 006 [3] 6 , 28, 127 💬 |
| 258 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CPS1 [1] CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 |
| 259 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CYP11B1 [1] CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 [2] 75, 193 💬 |
| 260 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CYP11B1 [1] CYP11B1 💬 |
D05019 D05019 💬 |
Metyrapone | 075 [2] 75, 193 💬 |
| 261 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CYP11B2 [1] CYP11B2 💬 |
D11061 D11061 💬 |
Osilodrostat | 075 [1] 75 💬 |
| 262 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CYP17A1 [1] CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 |
| 263 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CYP19A1 [1] CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 [3] 78, 86, 193 💬 |
| 264 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CYP19A1 [1] CYP19A1 💬 |
D00964 D00964 💬 |
Letrozole | 081 [2] 81, 89 💬 |
| 265 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DDC [1] DDC 💬 |
D03082 D03082 💬 |
Benserazide | 006 [1] 6 💬 |
| 266 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DDC [1] DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 002 [9] 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬 |
| 267 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
| 268 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHFR [2] DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
| 269 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHODH [1] DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
| 270 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DHODH [1] DHODH 💬 |
D10172 D10172 💬 |
Teriflunomide | 013 [3] 13, 25, 26 💬 |
| 271 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DNMT1 [3] DNMT1, DNMT3A, DNMT3B 💬 |
D03665 D03665 💬 |
Decitabine | 013 [3] 13, 60, 63 💬 |
| 272 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ENPP2 [1] ENPP2 💬 |
D11844 D11844 💬 |
Ziritaxestat | 051 [2] 51, 85 💬 |
| 273 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00939 D00939 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
| 274 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 |
| 275 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08056 D08056 💬 |
Ibandronate | 046 [3] 46, 49, 274 💬 |
| 276 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00941 D00941 💬 |
Pamidronic acid | 270 [3] 270, 271, 274 💬 |
| 277 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D07281 D07281 💬 |
Pamidronic acid | 270 [3] 270, 271, 274 💬 |
| 278 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D00942 D00942 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
| 279 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D03234 D03234 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
| 280 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
| 281 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
| 282 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D06378 D06378 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
| 283 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D06379 D06379 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
| 284 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
FDPS [1] FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
| 285 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GAA [1] GAA 💬 |
D03207 D03207 💬 |
Alglucosidase alfa | 256 [1] 256 💬 |
| 286 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GAA [1] GAA 💬 |
D11744 D11744 💬 |
Avalglucosidase alfa | 256 [1] 256 💬 |
| 287 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GAA [1] GAA 💬 |
D11798 D11798 💬 |
Cipaglucosidase alfa | 256 [1] 256 💬 |
| 288 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GAA [1] GAA 💬 |
D09605 D09605 💬 |
Duvoglustat | 256 [1] 256 💬 |
| 289 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GALNS [1] GALNS 💬 |
D10333 D10333 💬 |
Elosulfase alfa | 019 [1] 19 💬 |
| 290 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA [1] GBA 💬 |
D02810 D02810 💬 |
Alglucerase | 019 [1] 19 💬 |
| 291 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA [1] GBA 💬 |
D03020 D03020 💬 |
Imiglucerase | 019 [1] 19 💬 |
| 292 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA [1] GBA 💬 |
D09675 D09675 💬 |
Taliglucerase alfa | 019 [1] 19 💬 |
| 293 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GBA [1] GBA 💬 |
D09029 D09029 💬 |
Velaglucerase alfa | 019 [1] 19 💬 |
| 294 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GLA [1] GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 [1] 19 💬 |
| 295 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GLA [1] GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 [1] 19 💬 |
| 296 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
| 297 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
| 298 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GUCY2C [1] GUCY2C 💬 |
D09355 D09355 💬 |
Linaclotide | 006 [2] 6 , 97 💬 |
| 299 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
GUSB [1] GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 [1] 19 💬 |
| 300 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HAO1 [1] HAO1 💬 |
D11925 D11925 💬 |
Lumasiran | 234 [1] 234 💬 |
| 301 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 302 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
| 303 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00892 D00892 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 |
| 304 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 |
| 305 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
| 306 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
| 307 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
| 308 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D01915 D01915 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
| 309 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
| 310 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
| 311 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMOX1 [2] HMOX1, HMOX2 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 [1] 254 💬 |
| 312 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HPD [1] HPD 💬 |
D05177 D05177 💬 |
Nitisinone | 006 [3] 6 , 164, 241 💬 |
| 313 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HPRT1 [1] HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 |
| 314 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HPRT1 [1] HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 |
| 315 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HPRT1 [1] HPRT1 💬 |
D06109 D06109 💬 |
Tioguanine | 013 [2] 13, 37 💬 |
| 316 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HPRT1 [1] HPRT1 💬 |
D08603 D08603 💬 |
Tioguanine | 013 [2] 13, 37 💬 |
| 317 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDS [1] IDS 💬 |
D04499 D04499 💬 |
Idursulfase | 019 [1] 19 💬 |
| 318 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDS [1] IDS 💬 |
D11025 D11025 💬 |
Idursulfase beta | 019 [1] 19 💬 |
| 319 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDS [1] IDS 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 [1] 19 💬 |
| 320 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IDUA [1] IDUA 💬 |
D04670 D04670 💬 |
Laronidase | 019 [2] 19, 256 💬 |
| 321 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D01392 D01392 💬 |
Mizoribine | 046 [8] 46, 49, 51, 53, 66, 94, 222, 224 💬 |
| 322 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
| 323 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05094 D05094 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
| 324 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05095 D05095 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
| 325 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
| 326 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOA [1] MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 [1] 6 💬 |
| 327 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 [1] 6 💬 |
| 328 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D00505 D00505 💬 |
Phenelzine | 006 [1] 6 💬 |
| 329 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 [1] 6 💬 |
| 330 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
| 331 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOA [2] MAOA, MAOB 💬 |
D05459 D05459 💬 |
Phentermine | 097 [1] 97 💬 |
| 332 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D02562 D02562 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 333 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 334 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 [7] 2 , 5 , 6 , 13, 17, 58, 66 💬 |
| 335 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 [2] 6 , 17 💬 |
| 336 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D00785 D00785 💬 |
Selegiline | 006 [1] 6 💬 |
| 337 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
MAOB [1] MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 [1] 6 💬 |
| 338 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
| 339 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NPR1 [2] NPR1, NPR2 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
| 340 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NPR2 [1] NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 [1] 276 💬 |
| 341 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NQO1 [2] NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 [13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 342 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NQO1 [2] NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 [13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 343 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NQO1 [2] NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 [13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 344 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ODC1 [1] ODC1 💬 |
D07883 D07883 💬 |
Eflornithine | 065 [1] 65 💬 |
| 345 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PAH [1] PAH 💬 |
D11077 D11077 💬 |
Pegvaliase | 240 [1] 240 💬 |
| 346 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
| 347 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
| 348 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 349 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
| 350 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
| 351 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 352 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 353 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 354 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 355 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 356 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 357 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 358 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 051 [3] 51, 70, 124 💬 |
| 359 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
| 360 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
| 361 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
| 362 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
| 363 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
| 364 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 [2] 84, 299 💬 |
| 365 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01783 D01783 💬 |
Rolipram | 008 [2] 8 , 13 💬 |
| 366 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE4A [2] PDE4A, PDE5A 💬 |
D00302 D00302 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 |
| 367 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 368 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 369 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 |
| 370 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 [2] 86, 210 💬 |
| 371 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D02731 D02731 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
| 372 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D03260 D03260 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
| 373 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE5A [1] PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 |
| 374 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 375 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 376 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGES [3] PTGES, PTGS1, PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
| 377 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
| 378 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 379 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00903 D00903 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 380 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00904 D00904 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 381 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 382 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 383 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01475 D01475 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 384 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D02290 D02290 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 385 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 386 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 387 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 388 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 389 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 390 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01565 D01565 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 391 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D02110 D02110 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 392 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
| 393 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00813 D00813 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 394 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 395 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
| 396 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
| 397 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
| 398 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
| 399 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
| 400 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
| 401 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
| 402 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
| 403 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
| 404 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
| 405 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
| 406 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
| 407 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
| 408 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
| 409 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
| 410 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM1 [1] RRM1 💬 |
D01370 D01370 💬 |
Cladribine | 011 [3] 11, 13, 94 💬 |
| 411 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM1 [1] RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
| 412 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM1 [1] RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 [19] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
| 413 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM1 [1] RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 [19] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
| 414 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
RRM2 [1] RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
| 415 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
SMPD1 [1] SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 [1] 19 💬 |
| 416 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
SRD5A1 [2] SRD5A1, SRD5A2 💬 |
D03820 D03820 💬 |
Dutasteride | 001 [2] 1 , 2 💬 |
| 417 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
SRD5A2 [1] SRD5A2 💬 |
D00321 D00321 💬 |
Finasteride | 006 [1] 6 💬 |
| 418 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
TPH1 [2] TPH1, TPH2 💬 |
D09973 D09973 💬 |
Telotristat | 097 [1] 97 💬 |
| 419 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
TPO [1] TPO 💬 |
D00401 D00401 💬 |
Methimazole | 050 [1] 50 💬 |
| 420 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
TYMS [1] TYMS 💬 |
D01223 D01223 💬 |
Capecitabine | 094 [1] 94 💬 |
| 421 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
TYMS [1] TYMS 💬 |
D01244 D01244 💬 |
Tegafur | 046 [1] 46 💬 |
| 422 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG [1] UGCG 💬 |
D09893 D09893 💬 |
Eliglustat | 019 [1] 19 💬 |
| 423 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG [1] UGCG 💬 |
D11439 D11439 💬 |
Lucerastat | 019 [1] 19 💬 |
| 424 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG [1] UGCG 💬 |
D05032 D05032 💬 |
Miglustat | 019 [3] 19, 256, 299 💬 |
| 425 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
UGCG [1] UGCG 💬 |
D11633 D11633 💬 |
Venglustat | 006 [3] 6 , 19, 67 💬 |
| 426 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
VKORC1 [1] VKORC1 💬 |
D08354 D08354 💬 |
Phenindione | 065 [1] 65 💬 |
| 427 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
XDH [1] XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 [6] 6 , 46, 57, 66, 96, 97 💬 |
| 428 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
XDH [1] XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 |
| 429 | Metabolism of xenobiotics by cytochrome P450 💬 Related to 3 target genes, 1 drug (DrugBank) and 1 disease in DDrare |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 [1] 301 💬 |
| 430 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 431 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 432 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ABL1 [2] ABL1, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 433 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ABL1 [2] ABL1, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 434 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ABL1 [3] ABL1, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
| 435 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ABL1 [2] ABL1, PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 436 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ABL1 [2] ABL1, PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 437 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
| 438 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
BMPR2 [1] BMPR2 💬 |
D03779 D03779 💬 |
Dibotermin alfa | 034 [1] 34 💬 |
| 439 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
CDK6 [1] CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
| 440 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
DNMT1 [3] DNMT1, DNMT3A, DNMT3B 💬 |
D03665 D03665 💬 |
Decitabine | 013 [3] 13, 60, 63 💬 |
| 441 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 [5] 34, 51, 86, 89, 331 💬 |
| 442 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 [1] 94 💬 |
| 443 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
| 444 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
| 445 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
| 446 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 447 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
| 448 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
| 449 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
FGFR3 [1] FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
| 450 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
FGFR3 [3] FGFR3, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
| 451 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
HDAC1 [4] HDAC1, HDAC2, HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 019 [3] 19, 75, 96 💬 |
| 452 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
HMOX1 [1] HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 [1] 254 💬 |
| 453 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 454 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 455 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 456 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 457 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
| 458 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 459 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 460 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
| 461 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [4] 46, 51, 53, 271 💬 |
| 462 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D06402 D06402 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 463 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
| 464 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PDGFRB [2] PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 465 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PDGFRB [2] PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 466 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 467 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 468 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PRKCE [1] PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
| 469 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
| 470 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [18] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬 |
| 471 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬 |
| 472 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
| 473 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00903 D00903 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 474 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00904 D00904 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 475 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
| 476 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
| 477 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
| 478 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
| 479 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 480 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01475 D01475 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 481 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02290 D02290 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
| 482 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 483 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01122 D01122 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 484 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D04490 D04490 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 485 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D06606 D06606 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
| 486 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 487 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01565 D01565 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 488 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02110 D02110 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
| 489 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
| 490 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00813 D00813 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 491 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
| 492 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
| 493 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
| 494 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
| 495 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
| 496 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
| 497 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
| 498 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
| 499 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
| 500 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
| 501 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
| 502 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
| 503 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ROCK1 [1] ROCK1 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
| 504 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
TGFB2 [1] TGFB2 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [4] 51, 85, 222, 274 💬 |
| 505 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
| 506 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 507 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
| 508 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
| 509 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
| 510 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
CLCN2 [1] CLCN2 💬 |
D04790 D04790 💬 |
Lubiprostone | 006 [4] 6 , 13, 290, 299 💬 |
| 511 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
HMOX1 [2] HMOX1, HMOX2 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 [1] 254 💬 |
| 512 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
| 513 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 [2] 113, 299 💬 |
| 514 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D01125 D01125 💬 |
Calcipotriol | 036 [2] 36, 51 💬 |
| 515 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
| 516 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [25] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
| 517 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D00299 D00299 💬 |
Dihydrotachysterol | 006 [2] 6 , 85 💬 |
| 518 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D07578 D07578 💬 |
Eldecalcitol | 046 [1] 46 💬 |
| 519 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬 |
| 520 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 42 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [4] 19, 66, 218, 238 💬 |
| 521 | Mitophagy - animal 💬 Related to 2 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
| 522 | Mitophagy - animal 💬 Related to 2 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
| 523 | Mitophagy - animal 💬 Related to 2 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 524 | Mitophagy - animal 💬 Related to 2 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
| 525 | Mitophagy - animal 💬 Related to 2 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
| 526 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
| 527 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
| 528 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
| 529 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 [1] 63 💬 |
| 530 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 531 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D01712 D01712 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 532 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D02017 D02017 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 533 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 534 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06104 D06104 💬 |
Theophylline | 236 [2] 236, 299 💬 |
| 535 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 536 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 [9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
| 537 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
CACNA1B [1] CACNA1B 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
| 538 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D02004 D02004 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 539 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
| 540 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
| 541 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00633 D00633 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 542 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
| 543 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
| 544 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
| 545 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 002 [8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬 |
| 546 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D00502 D00502 💬 |
Pergolide | 006 [1] 6 💬 |
| 547 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
| 548 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 [1] DRD1 💬 |
D11431 D11431 💬 |
Tavapadon | 006 [1] 6 💬 |
| 549 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 [2] 13, 206 💬 |
| 550 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D08861 D08861 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 |
| 551 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [7] 2 , 10, 13, 18, 65, 149, 206 💬 |
| 552 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [1] GABRA1 💬 |
D00548 D00548 💬 |
Etomidate | 006 [1] 6 💬 |
| 553 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 [2] 8 , 75 💬 |
| 554 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D11149 D11149 💬 |
Brexanolone | 205 [1] 205 💬 |
| 555 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00267 D00267 💬 |
Chlordiazepoxide | 046 [1] 46 💬 |
| 556 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00693 D00693 💬 |
Chlordiazepoxide | 046 [1] 46 💬 |
| 557 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
| 558 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00280 D00280 💬 |
Clonazepam | 006 [1] 6 💬 |
| 559 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D07784 D07784 💬 |
Delorazepam | 006 [3] 6 , 46, 97 💬 |
| 560 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
| 561 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D02624 D02624 💬 |
Eszopiclone | 006 [3] 6 , 13, 46 💬 |
| 562 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01514 D01514 💬 |
Etizolam | 046 [1] 46 💬 |
| 563 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬 |
| 564 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 [2] 201, 206 💬 |
| 565 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 [4] 145, 152, 158, 206 💬 |
| 566 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00365 D00365 💬 |
Lorazepam | 036 [2] 36, 231 💬 |
| 567 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬 |
| 568 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00696 D00696 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬 |
| 569 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D05028 D05028 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬 |
| 570 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 [10] 6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬 |
| 571 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
| 572 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00706 D00706 💬 |
Zolpidem | 005 [3] 5 , 6 , 46 💬 |
| 573 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D08690 D08690 💬 |
Zolpidem | 005 [3] 5 , 6 , 46 💬 |
| 574 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01372 D01372 💬 |
Zopiclone | 006 [1] 6 💬 |
| 575 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
D00636 D00636 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 576 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
| 577 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00836 D00836 💬 |
Buprenorphine | 046 [3] 46, 70, 298 💬 |
| 578 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D07132 D07132 💬 |
Buprenorphine | 046 [3] 46, 70, 298 💬 |
| 579 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D01481 D01481 💬 |
Dihydrocodeine | 310 [1] 310 💬 |
| 580 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D07831 D07831 💬 |
Dihydrocodeine | 310 [1] 310 💬 |
| 581 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00320 D00320 💬 |
Fentanyl | 046 [4] 46, 70, 215, 231 💬 |
| 582 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D01399 D01399 💬 |
Fentanyl | 046 [4] 46, 70, 215, 231 💬 |
| 583 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00839 D00839 💬 |
Hydromorphone | 070 [1] 70 💬 |
| 584 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08047 D08047 💬 |
Hydromorphone | 070 [1] 70 💬 |
| 585 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00729 D00729 💬 |
Loperamide | 013 [2] 13, 97 💬 |
| 586 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D07113 D07113 💬 |
Loperamide | 013 [2] 13, 97 💬 |
| 587 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08144 D08144 💬 |
Loperamide | 013 [2] 13, 97 💬 |
| 588 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D01383 D01383 💬 |
Meperidine | 298 [1] 298 💬 |
| 589 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08343 D08343 💬 |
Meperidine | 298 [1] 298 💬 |
| 590 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00842 D00842 💬 |
Morphine | 036 [6] 36, 46, 70, 85, 86, 298 💬 |
| 591 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D02271 D02271 💬 |
Morphine | 036 [6] 36, 46, 70, 85, 86, 298 💬 |
| 592 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08233 D08233 💬 |
Morphine | 036 [6] 36, 46, 70, 85, 86, 298 💬 |
| 593 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00843 D00843 💬 |
Nalbuphine | 085 [1] 85 💬 |
| 594 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08246 D08246 💬 |
Nalbuphine | 085 [1] 85 💬 |
| 595 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05111 D05111 💬 |
Nalmefene | 006 [1] 6 💬 |
| 596 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D01340 D01340 💬 |
Naloxone | 006 [2] 6 , 226 💬 |
| 597 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08249 D08249 💬 |
Naloxone | 006 [2] 6 , 226 💬 |
| 598 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
| 599 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
| 600 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D03783 D03783 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
| 601 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
| 602 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05462 D05462 💬 |
Oxycodone | 006 [7] 6 , 13, 46, 70, 226, 231, 298 💬 |
| 603 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08323 D08323 💬 |
Oxymorphone | 070 [1] 70 💬 |
| 604 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D01177 D01177 💬 |
Remifentanil | 006 [2] 6 , 70 💬 |
| 605 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08473 D08473 💬 |
Remifentanil | 006 [2] 6 , 70 💬 |
| 606 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00845 D00845 💬 |
Sufentanil | 070 [2] 70, 280 💬 |
| 607 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05938 D05938 💬 |
Sufentanil | 070 [2] 70, 280 💬 |
| 608 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D01355 D01355 💬 |
Tramadol | 046 [5] 46, 70, 78, 226, 271 💬 |
| 609 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08623 D08623 💬 |
Tramadol | 046 [5] 46, 70, 78, 226, 271 💬 |
| 610 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08639 D08639 💬 |
Trimebutine | 051 [1] 51 💬 |
| 611 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
| 612 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00718 D00718 💬 |
Flavoxate | 226 [1] 226 💬 |
| 613 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
| 614 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 051 [3] 51, 70, 124 💬 |
| 615 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
| 616 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
| 617 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D02085 D02085 💬 |
Milrinone | 294 [1] 294 💬 |
| 618 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
| 619 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE4A [1] PDE4A 💬 |
D00302 D00302 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 |
| 620 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 |
| 621 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 [2] 84, 299 💬 |
| 622 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01783 D01783 💬 |
Rolipram | 008 [2] 8 , 13 💬 |
| 623 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
| 624 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 625 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
| 626 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
| 627 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 628 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
| 629 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
| 630 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
| 631 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
| 632 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 [2] 96, 156 💬 |
| 633 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
| 634 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
| 635 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
| 636 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
| 637 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
| 638 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 639 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [41] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 640 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [4] 13, 34, 89, 331 💬 |
| 641 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
| 642 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
| 643 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 644 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
PRKAA1 [2] PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 [24] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 645 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 646 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 647 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 648 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 649 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 650 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 651 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
| 652 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
| 653 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 654 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [6] 28, 34, 51, 85, 227, 331 💬 |
| 655 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |