Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome

Valproic acid 💬

[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
5	Progressive supranuclear palsy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
26	HTLV-1-associated myelopathy
65	Primary immunodeficiency
85	Idiopathic interstitial pneumonia
90	Retinitis pigmentosa
102	Rubinstein-Taybi syndrome
127	Frontotemporal lobar degeneration
222	Primary nephrotic syndrome
233	Wolfram syndrome
256	Muscle glycogenosis

2

[7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome

Zonisamide 💬

[1] 6 💬

3

[7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome

Flunarizine 💬

[1] 149 💬