Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Riboflavin [1] Riboflavin[2] Riboflavin; Vitamin B2; --[7] 38, 46, 96, 97, 162, 168, 265
2 Didanosine [1] Didanosine[1] Didanosine; --[2] 25, 265
3 Lamivudine [1] Lamivudine[4] COMBIVIR; Epivir; Lamivudine; Triumeq; --[8] 2, 26, 42, 46, 135, 256, 265, 325
4 Zidovudine [1] Zidovudine[3] COMBIVIR; Retrovir; Zidovudine; --[7] 25, 26, 94, 135, 265, 325, 331
5 Ritonavir [1] Ritonavir[2] Norvir; Ritonavir; --[3] 2, 86, 265
6 Saquinavir [1] Saquinavir[1] Saquinavir; --[2] 86, 265
7 Simvastatin [1] Simvastatin[3] Simvastatin; Simvastatina; Simvastatine; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
8 Nevirapine [1] Nevirapine[1] Nevirapine; --[1] 265
9 Stavudine [1] Stavudine[1] Stavudine; --[1] 265
10 Pyrimethamine [1] Pyrimethamine[2] Daraprim; PYRIMETHAMINE; --[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265
11 Caffeine [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
12 Fenofibrate [1] Fenofibrate[1] Fenofibrate; [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265
13 Amprenavir [1] Amprenavir[1] Amprenavir; --[1] 265
14 Efavirenz [1] Efavirenz[2] Efavirenz; SUSTIVA; --[1] 265
15 Emtricitabine [1] Emtricitabine[2] Emtricitabine; TRUVADA; --[4] 25, 93, 265, 325
16 Lopinavir [1] Lopinavir[2] Kaletra; Lopinavir; --[2] 93, 265
17 Caffeine hydrate [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
18 Levocarnitine [1] Levocarnitine[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal; --[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
19 Enfuvirtide [1] Enfuvirtide[1] Enfuvirtide; --[2] 25, 265
20 Mecasermin [1] Mecasermin[3] Increlex; Mecasermin; MECASERMINA; [2] GHR,
IGF1R 💬		[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[6] 65, 78, 96, 168, 265, 299
21 Indinavir [1] Indinavir[1] Indinavir; --[1] 265
22 Metformin [1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
23 Metreleptin [1] Metreleptin[3] METRELEPTIN; Myalept; R-metHuLeptin; [1] LEPR 💬[6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265
24 Pegvisomant [1] Pegvisomant[1] Pegvisomant; [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 78, 265
25 Tenofovir [1] Tenofovir[1] Tenofovir; --[6] 2, 13, 25, 93, 265, 325
26 Tesamorelin [1] Tesamorelin[2] GHRH; Tesamorelin; [1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265
27 Raltegravir [1] Raltegravir[2] ISENTRESS; Raltegravir; --[4] 13, 26, 93, 265
28 Abacavir [1] Abacavir[4] Abacavir; Abacavir sulfate; Triumeq; Ziagen; --[5] 2, 135, 256, 265, 325
29 Acipimox [1] Acipimox[1] Acipimox; --[2] 78, 265
30 Atazanavir [1] Atazanavir[2] Atazanavir; Reyataz; --[1] 265
31 Atorvastatin [1] Atorvastatin[3] Atorvastatin; Atorvastatin calcium; Lipitor; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
32 Diosmin [1] Diosmin[1] Diosmin; --[3] 46, 97, 265
33 Nelfinavir [1] Nelfinavir[1] Nelfinavir; --[3] 49, 265, 331
34 Pioglitazone [1] Pioglitazone[1] Pioglitazone; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
35 Pravastatin [1] Pravastatin[2] Pravastatin; Pravastatin sodium; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
36 Rosiglitazone [1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
37 Thiamine [1] Thiamine[2] Thiamine; Vitamin B1; --[4] 8, 93, 145, 265
38 Tipranavir [1] Tipranavir[1] Tipranavir; --[1] 265
39 Obeticholic acid [1] Obeticholic acid[4] 6-ECDCA; 6-ethylchenodeoxycholic acid; Obeticholic Acid; Ocaliva; [1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296
40 Dolutegravir [1] Dolutegravir[2] Dolutegravir; Triumeq; --[2] 2, 265
41 Baricitinib [1] Baricitinib[2] Baricitinib; Olumiant; [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
42 Doravirine [1] Doravirine[1] Doravirine; --[1] 265
43 Cholic acid [1] Cholic Acid[1] CHOLIC ACID; [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310
44 Volanesorsen [1] Volanesorsen[1] Volanesorsen; [1] APOC3 💬[2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265
45 Setmelanotide [1] Setmelanotide[1] Setmelanotide; [1] MC4R 💬[1] Neuroactive ligand-receptor interaction 💬[2] 202, 265