Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen 💬[1] Acetaminophen (Tukol Max Action Sinus Liquid)[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Adenosine 💬[1] Adenosine (ACTIBEAU Intensive Moisturizing Facial Mask)[2] Adenosine; Ginseng[4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬 		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65 💬
3 Alendronic acid 💬[1] Alendronic acid (Act Alendronate)[3] Alendronate; Alendronate sodium; ALENDRONIC ACID[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299 💬
4 Alginic acid 💬[1] Alginic acid (Tums Dual Action)[3] Algin; Alginate; Alginic acid--[4] 51, 53, 97, 299 💬
5 Allantoin 💬[1] Allantoin (STACEYS LAB ActiGen Ampoule)[1] ALLANTOIN--[1] 36 💬
6 Aluminum hydroxide 💬[1] Aluminum hydroxide (FAST ACTING Heartburn Relief)[2] Aluminium hydroxide; Aluminum hydroxide--[2] 11, 46 💬
7 Amlodipine 💬[1] Amlodipine (Act Amlodipine)[1] Amlodipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 67, 298 💬
8 Ammonium chloride 💬[1] Ammonium chloride (Ecopp Long Acting Antibacterial Disinfectant)[1] Ammonium chloride--[3] 96, 107, 251 💬
9 Ascorbic acid 💬[1] Ascorbic acid (Vitamine C 500 Action Prolongee)[4] Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C--[8] 10, 97, 192, 206, 210, 211, 212, 298 💬
10 Aspirin 💬[1] Acetylsalicylic acid (Excedrin PM Triple Action Caplets and Excedrin Extra Strength Pain Reliever)[2] ACETYLSALICYLIC ACID; Aspirin[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[12] 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231 💬
11 Atacicept 💬[1] Atacicept (Human Transmembrane Activator and CAML Interactor)[2] ATACICEPT; TACI-Fc5[2] TNFSF13,
TNFSF13B 💬 		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 49, 66 💬
12 Atenolol 💬[1] Atenolol (Act Atenolol)[1] ATENOLOL[1] ADRB1 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
13 Azithromycin 💬[1] Azithromycin (Act Azithromycin)[5] Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX--[6] 13, 84, 85, 96, 228, 299 💬
14 Azithromycin 💬[1] Azithromycin (Act Azithromycin)[5] AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax--[6] 13, 84, 85, 96, 228, 299 💬
15 beta Carotene 💬[1] Beta carotene (Fusion Activator Formula Tab)[3] Beta carotene; Beta-Carotene; BETACAROTENE--[2] 13, 96 💬
16 Bezafibrate 💬[1] Bezafibrate (Act-bezafibrate SR)[1] Bezafibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[7] 20, 93, 94, 160, 296, 316, 324 💬
17 Biotin 💬[1] Biotin (Multi-actin)[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7--[5] 2, 8, 10, 13, 20 💬
18 Bosentan 💬[1] Bosentan (Act Bosentan)[2] BOSENTAN; TRACLEER[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
19 Bosentan 💬[1] Bosentan (Act Bosentan)[2] BOSENTAN; TRACLEER[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
20 Cabergoline 💬[1] Cabergoline (Act Cabergoline)[3] CABERGOLINA; Cabergoline; DOSTINEX[2] DRD2,
PRL 💬 		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75 💬
21 Caffeine 💬[1] Caffeine (Rx Act headache formula added strength)[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
22 Caffeine hydrate 💬[1] Caffeine (Rx Act headache formula added strength)[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
23 Calcium carbonate 💬[1] Calcium carbonate (Act Etidrocal)[3] Calcio carbonato; Calcium; Calcium carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
24 Calcium carbonate 💬[1] Calcium carbonate (Act Etidrocal)[3] Calcio carbonato; Calcium; Calcium carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
25 Candesartan cilexetil 💬[1] Candesartan cilexetil (Act Candesartan/hct)[1] CANDESARTAN[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67 💬
26 Capsaicin 💬[1] Capsaicin (Arthricare for Women Multi-action)[2] Capsaicin; Qutenza[1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226 💬
27 Celecoxib 💬[1] Celecoxib (Act Celecoxib)[2] CELEBREX; Celecoxib[1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
28 Cetirizine 💬[1] Cetirizine (Rx Act all day allergy relief)[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300 💬
29 Chlorphenamine 💬[1] Chlorpheniramine (Actifed PE)[1] Clorfenamina[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14 💬
30 Cholecalciferol 💬[1] Cholecalciferol (Active FE)[5] Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
31 Ciprofloxacin 💬[1] Ciprofloxacin (Act Ciprofloxacin)[2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE--[5] 2, 60, 96, 97, 299 💬
32 Citalopram 💬[1] Citalopram (Act Citalopram)[1] Citalopram[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
33 Citric acid monohydrate 💬[1] Citric acid (bdr Re-action natural low base skin refiner exfoliation essence)[1] Citric acid--[2] 53, 291 💬
34 Clarithromycin 💬[1] Clarithromycin (Act Clarithromycin XL)[1] Clarithromycin--[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
35 Clopidogrel 💬[1] Clopidogrel (Act Clopidogrel)[1] Clopidogrel[1] P2RY12 💬 [1] Platelet activation 💬[3] 49, 51, 86 💬
36 Clopidogrel besilate 💬[1] Clopidogrel (Act Clopidogrel)[1] Clopidogrel[1] P2RY12 💬 [1] Platelet activation 💬[3] 49, 51, 86 💬
37 Clopidogrel hydrochloride 💬[1] Clopidogrel (Act Clopidogrel)[1] Clopidogrel[1] P2RY12 💬 [1] Platelet activation 💬[3] 49, 51, 86 💬
38 Cobamamide 💬[1] Cobamamide (Acti-folic + Dibencozide Caplets)[1] Cobamamide--[1] 299 💬
39 Corticorelin ovine triflutate 💬
(Acthrel (TN))		[1] Corticorelin ovine triflutate (Acthrel)[1] Acthrel[2] CRHR1,
CRHR2 💬 		[4] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75 💬
40 Corticotropin 💬
(ACTH (TN), Acthar (TN))		[1] Corticotropin (ACTH)[5] ACTH; ACTHAR; Adrenocorticotropic Hormone; Corticotrophin; Corticotropin[1] MC2R 💬 [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[12] 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
41 Cyanocobalamin 💬[1] Cyanocobalamin (Multi-actin)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
42 Cyanocobalamin Co 57 💬[1] Cyanocobalamin (Multi-actin)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
43 Cyanocobalamin Co 58 💬[1] Cyanocobalamin (Multi-actin)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
44 Cyanocobalamin Co 60 💬[1] Cyanocobalamin (Multi-actin)[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
45 Desloratadine 💬[1] Desloratadine (Aerius Dual Action 24 Hour)[1] Desloratadine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13 💬
46 Dextran 1 💬[1] Dextran (Visine for Red Eye Triple Action)[1] Dextran--[4] 2, 62, 96, 97 💬
47 Dextromethorphan 💬[1] Dextromethorphan (Tussin Long Acting Cough READYINCASE)[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
48 Diclofenac 💬[1] Diclofenac (Act Diclo-miso)[3] Diclofenac; Diclofenac Sodium; Diclofenac SR[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271 💬
49 Diltiazem 💬[1] Diltiazem (Act Diltiazem T)[2] Diltiazem; Diltiazem Hydrochloride[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86 💬
50 Diphenhydramine 💬[1] Diphenhydramine (Excedrin PM Triple Action Caplets)[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256 💬
51 Donepezil 💬[1] Donepezil (Act Donepezil ODT)[3] ARICEPT; Donepezil; Donepezil Hydrochloride[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
52 Dorzolamide 💬[1] Dorzolamide (Act Dorzotimolol)[1] Dorzolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90 💬
53 Doxycycline 💬[1] Doxycycline (Acticlate CAP)[4] Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
54 Doxycycline 💬[1] Doxycycline (Acticlate CAP)[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
55 Dutasteride 💬[1] Dutasteride (Act Dutasteride)[2] Dutasterida; Dutasteride[2] SRD5A1,
SRD5A2 💬 		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2 💬
56 Enalapril 💬[1] Enalapril (Act Enalapril)[2] Enalapril; Enalapril Maleate[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222 💬
57 Ephedrine 💬[1] Ephedrine (Bronkaid Dual Action Formula)[3] Efedrina; Ephedrine; EPHEDRINE HYDROCHLORIDE[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11 💬
58 Ergocalciferol 💬[1] Ergocalciferol (Activated ergosterol)[3] Ergocalciferol; Vitamin D; Vitamin D2[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299 💬
59 Escitalopram 💬[1] Escitalopram (Act Escitalopram)[3] Citalopram; Escitalopram; Escitalopram oxalate[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
60 Estradiol 💬[1] Estradiol (Activelle Ld)[1] Estradiol[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299 💬
61 Ethanol 💬[1] Ethanol (Victis Active Defense Essential)[3] Alcohol; Ethanol; PREDNISONE--[5] 58, 97, 279, 280, 298 💬
62 Etidronic acid 💬[1] Etidronic acid (Act Etidrocal)[1] Etidronate--[1] 27 💬
63 Ezetimibe 💬[1] Ezetimibe (Act Ezetimibe)[2] Ezetimibe; Ezetrol[1] NPC1L1 💬 [1] Fat digestion and absorption 💬[4] 49, 79, 93, 260 💬
64 Famciclovir 💬[1] Famciclovir (Act Famciclovir)[1] Famciclovir--[2] 11, 13 💬
65 Famotidine 💬[1] Famotidine (Basic Care Dual Action Complete)[2] FAMOTIDINA; Famotidine[1] HRH2 💬 [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 86, 98, 107 💬
66 Fentanyl 💬[1] Fentanyl (Actiq)[1] Fentanyl[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 215 💬
67 Finasteride 💬[1] Finasteride (Act Finasteride)[1] Finasteride[1] SRD5A2 💬 [3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6 💬
68 Fluconazole 💬[1] Fluconazole (Act Fluconazole)[2] Diflucan; FLUCONAZOLE--[2] 96, 225 💬
69 Fluoxetine 💬[1] Fluoxetine (Act Fluoxetine)[5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206 💬
70 Fluticasone propionate 💬[1] Fluticasone propionate (Flovent Inhalers-aem Inh-orl 50mcg/actuation)[3] Flovent; Fluticasone; FLUTICASONE PROPIONATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 98, 228 💬
71 Folic acid 💬[1] Folic acid (Acti-folic + Dibencozide Caplets)[5] Acide folique; Folate; Folic acid; Multivitamin; Nicotinamide--[6] 6, 41, 46, 49, 84, 296 💬
72 Fulvestrant 💬[1] Fulvestrant (Act Fulvestrant)[2] Faslodex; Fulvestrant[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 49, 86 💬
73 Furosemide 💬[1] Furosemide (Active-Medicated specimen collection kit)[2] Furosemide; Furosemide Injection[1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 86 💬
74 Gabapentin 💬[1] Gabapentin (ACTIVE-PAC with Gabapentin)[4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
75 Glycerin 💬[1] Glycerin (TONYMOLY Bio EX Active-Cell Night Cream)[2] Bee venom; Glycerol--[5] 6, 13, 79, 316, 317 💬
76 Haloperidol 💬[1] Haloperidol (Haloperidol Long Acting)[1] Haloperidol[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8 💬
77 Hyaluronic acid 💬[1] Hyaluronic acid (ACTS38 BoswelliaGel)[2] Hyaluronate; Hyaluronic acid--[6] 46, 53, 70, 97, 226, 231 💬
78 Hydrochlorothiazide 💬[1] Hydrochlorothiazide (Act Telmisartan/hct)[2] Esidrix; HYDROCHLOROTHIAZIDE[1] SLC12A3 💬 [1] 💬[4] 13, 67, 225, 235 💬
79 Hydrocortisone 💬
(Acticort (TN))		[1] Hydrocortisone[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
80 Hydrocortisone acetate 💬[1] Hydrocortisone acetate (Actinac Pws)[2] Hydrocortisone; HYDROCORTISONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 97 💬
81 Ibuprofen 💬[1] Ibuprofen (Rx Act Ibuprofen Childrens)[2] Ibuprofen; IBUPROFEN 200MG[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299 💬
82 Imatinib 💬[1] Imatinib (Imatinib Actavis)[4] Gleevec; GLIVEC; Imatinib; Imatinib Mesylate[3] ABL1,
KIT,
PDGFRA 💬 		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
83 Insulin human 💬[1] Insulin human (Actrapid Innolet)[1] Human insulin[1] INSR 💬 [22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 96, 156 💬
84 Interferon gamma-1b 💬
(Actimmune (TN))		[1] Interferon gamma-1b (Actimmune)[2] ACTIMMUNE; INTERFERON GAMMA-1B[2] IFNGR1,
IFNGR2 💬 		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
85 Iodine 💬[1] Iodine (Sky-Living Water MT Activition Liquid)[2] Iodine; Iodo--[2] 28, 46 💬
86 Irbesartan 💬[1] Irbesartan (Act Irbesartan/hct)[2] Aprovel; IRBESARTAN[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 66, 167, 168, 222 💬
87 Levetiracetam 💬[1] Levetiracetam (Levetiracetam Actavis)[2] KEPPRA; Levetiracetam[1] SV2A 💬 [1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
88 Levofloxacin 💬[1] Levofloxacin (Act Levofloxacin)[2] Levaquin; Levofloxacin--[4] 46, 53, 84, 299 💬
89 Levofloxacin 💬[1] Levofloxacin (Act Levofloxacin)[2] Levaquin; Levofloxacin--[4] 46, 53, 84, 299 💬
90 Levonorgestrel 💬[1] Levonorgestrel (Take Action)[1] LEVONORGESTREL[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
91 Lidocaine 💬[1] Lidocaine (Zcaine Fast Acting Anesthetic)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
92 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine (Zcaine Fast Acting Anesthetic)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
93 Lisinopril 💬[1] Lisinopril (Act Lisinopril)[2] LISINOPRIL; ZESTRIL[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222 💬
94 Lisinopril 💬[1] Lisinopril (Act Lisinopril)[2] Lisinopril; Zestril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222 💬
95 Loperamide 💬[1] Loperamide (Rx Act Anti Diarrheal)[2] LOPERAMIDE; Loperamide hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97 💬
96 Losartan 💬[1] Losartan (Act Losartan/hct)[3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
97 Lovastatin 💬[1] Lovastatin (Act Lovastatin)[1] Lovastatin[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
98 Magnesium hydroxide 💬[1] Magnesium hydroxide (Phillips Dual Action)[1] Magnesium hydroxide--[1] 284 💬
99 Magnesium oxide 💬[1] Magnesium oxide (Active FE)[1] Magnesium oxide--[3] 6, 166, 291 💬
100 Maltodextrin 💬[1] Maltodextrin (Re-action E)[1] Maltodextrin--[4] 6, 13, 96, 97 💬
101 Meloxicam 💬[1] Meloxicam (Act Meloxicam)[1] Meloxicam[1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 46, 49, 271, 296 💬
102 Memantine 💬[1] Memantine (Act Memantine)[3] EBIXA; Memantine; Memantine hydrochloride[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
103 Metformin 💬[1] Metformin (Act Metformin)[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
104 Methylphenidate 💬[1] Methylphenidate (Act Methylphenidate ER)[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
105 Mineral oil 💬[1] Mineral oil (Phillips Dual Action)[1] Paraffin Oil--[1] 291 💬
106 Misoprostol 💬[1] Misoprostol (Act Diclo-miso)[1] Misoprostol[3] PTGER2,
PTGER3,
PTGER4 💬 		[9] Calcium signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway 💬[3] 46, 70, 271 💬
107 Moxifloxacin 💬[1] Moxifloxacin (Act Moxifloxacin)[2] Moxifloxacin; Moxifloxacin hydrochloride--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
108 Nabilone 💬[1] Nabilone (Act Nabilone)[1] Nabilone[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 6, 13, 127 💬
109 Naproxen 💬[1] Naproxen (Rx Act All Day Pain Relief)[5] Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271 💬
110 Neomycin 💬[1] Neomycin (Dual Action Cream)[1] Neomycin--[3] 96, 97, 296 💬
111 Niacin 💬[1] Niacin (Fusion Activator Formula Tab)[2] Niacin; Nicotinic acid--[3] 6, 78, 79 💬
112 Niacinamide 💬[1] Nicotinamide (ACTIBEAU Intensive Moisturizing Facial Mask)[3] Multivitamin; Niacinamide; NICOTINAMIDE--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
113 Nifedipine 💬[1] Nifedipine (Nu-nifedipine-PA - Prolonged Action Tab)[1] Nifedipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 50, 81 💬
114 Norethindrone 💬[1] Norethisterone (Activelle Ld)[3] Norethindrone; Ortho-novum; Ortho-Novum 777[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[4] 13, 46, 49, 299 💬
115 Olanzapine 💬[1] Olanzapine (Act Olanzapine)[2] OLANZAPINE; Zyprexa[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8 💬
116 Oxycodone 💬[1] Oxycodone (Act Oxycodone CR)[2] OXYCODONE; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
117 Pantoprazole 💬[1] Pantoprazole (Act Pantoprazole)[1] PANTOPRAZOLE[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65 💬
118 Paroxetine 💬[1] Paroxetine (Act Paroxetine)[1] Paroxetine[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85 💬
119 Petrolatum 💬[1] Petrolatum (Orajel Multi-action Cold Sore Medicine)[1] Petrolatum--[1] 158 💬
120 Phenylephrine 💬[1] Phenylephrine (Actifed PE Plus)[1] Phenylephrine[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22 💬
121 Pioglitazone 💬
(Actos (TN))		[1] Pioglitazone (Actoplus Met)[1] Pioglitazone[1] PPARG 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
122 Potassium 💬[1] Potassium (Multi-actin)[1] Potassium--[13] 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
123 Pramipexole 💬[1] Pramipexole (Act Pramipexole)[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[3] DRD2,
DRD3,
DRD4 💬 		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20 💬
124 Pravastatin 💬[1] Pravastatin (Act Pravastatin)[2] Pravastatin; Pravastatin sodium[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
125 Pregabalin 💬[1] Pregabalin (Act Pregabalin)[2] Lyrica; Pregabalin[4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬 		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298 💬
126 Progesterone 💬[1] Progesterone (Act Progesterone Injection)[1] Progesterone[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[2] 76, 299 💬
127 Pseudoephedrine 💬[1] Pseudoephedrine (Actifed DM Syrup)[1] Pseudoephedrine[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
128 Pyridoxine 💬[1] Pyridoxine (Active FE)[2] Pyridoxine; Vitamin B6--[5] 6, 93, 145, 206, 320 💬
129 Quetiapine 💬[1] Quetiapine (Act Quetiapine)[2] Quetiapine; Seroquel[2] DRD2,
HTR2A 💬 		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13 💬
130 Raloxifene 💬[1] Raloxifene (Act Raloxifene)[2] Raloxifene; Raloxifene hydrochloride[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 46 💬
131 Ramipril 💬[1] Ramipril (Act Ramipril)[1] Ramipril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257 💬
132 Ranitidine 💬[1] Ranitidine (Rx Act Heartburn Relief)[1] Ranitidine[1] HRH2 💬 [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65 💬
133 Repaglinide 💬[1] Repaglinide (Act Repaglinide)[1] Repaglinide[2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
134 Riboflavin 💬[1] Riboflavin (Active OB)[2] Riboflavin; Vitamin B2--[7] 38, 46, 96, 97, 162, 168, 265 💬
135 Risedronic acid 💬[1] Risedronic acid (Actonel Plus Calcium)[3] Risedronate; Risedronate Sodium; Risedronic acid[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
136 Risperidone 💬[1] Risperidone (Act Risperidone)[1] Risperidone[2] DRD2,
HTR2A 💬 		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206 💬
137 Rivastigmine 💬[1] Rivastigmine (Rivastigmine Actavis)[3] EXELON; Rivastigmine; Rivastigmine Transdermal System[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13 💬
138 Rosuvastatin 💬[1] Rosuvastatin (Act Rosuvastatin)[3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
139 Salicylic acid 💬[1] Salicylic acid (Nu Skin Clear Action Acne Medication Day Treatment)[2] 2-Hydroxybenzoic acid; Salicylic acid--[1] 97 💬
140 Sertraline 💬[1] Sertraline (Act Sertraline)[1] Sertraline[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206 💬
141 Sildenafil 💬[1] Sildenafil (Sildenafil Actavis)[6] Mysildecard; REVATIO; SILDENAFIL; SILDENAFIL CITRATE; SILDENAFILO; VIAGRA[1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
142 Simvastatin 💬[1] Simvastatin (Act Simvastatin)[3] Simvastatin; Simvastatina; Simvastatine[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
143 Sodium fluoride 💬[1] Sodium fluoride (AQUAFRESH Whitening Multi Action)[1] Sodium fluoride--[1] 51 💬
144 Solifenacin 💬[1] Solifenacin (Act Solifenacin)[2] Solifenacin; Solifenacin Succinate[1] CHRM3 💬 [11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
145 Spectinomycin 💬[1] Spectinomycin (Actinospectacina)[0] ---
146 Tadalafil 💬[1] Tadalafil (Act Tadalafil)[4] Adcirca; CIALIS; Tadalafil; TADALAFILO[1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210 💬
147 Telmisartan 💬[1] Telmisartan (Act Telmisartan)[1] Telmisartan[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 67 💬
148 Temozolomide 💬[1] Temozolomide (Act Temozolomide)[1] Temozolomide--[1] 34 💬
149 Terbinafine 💬[1] Terbinafine (Act Terbinafine)[1] Terbinafine--[3] 96, 97, 271 💬
150 Tetracycline 💬[1] Tetracycline (Actisite)[2] Tetracyclin; Tetracycline--[5] 13, 36, 46, 53, 97 💬
151 Thiamine 💬[1] Thiamine (Multi-actin)[2] THIAMINE; Vitamin B1--[4] 8, 93, 145, 265 💬
152 Timolol 💬[1] Timolol (Act Dorzotimolol)[2] Timolol; TIMOLOL MALEATE[2] ADRB1,
ADRB2 💬 		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227 💬
153 Timolol 💬[1] Timolol (Act Dorzotimolol)[2] Timolol; TIMOLOL MALEATE[2] ADRB1,
ADRB2 💬 		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227 💬
154 Tocilizumab 💬
(Actemra (TN))		[1] Tocilizumab (Actemra)[3] Actemra; RoActemra; TOCILIZUMAB[1] IL6R 💬 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
155 Topotecan 💬[1] Topotecan (Topotecan Actavis)[1] Topotecan[1] TOP1 💬 [1] 💬[1] 25 💬
156 Tramadol 💬[1] Tramadol (Act Tramadol/acet)[2] Tramadol; Ultracet[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271 💬
157 Tremelimumab 💬
(Tremelimumab-actl)		[1] Tremelimumab[1] Ticilimumab[1] CTLA4 💬 [4] Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬[1] 96 💬
158 Ubidecarenone 💬[1] Ubidecarenone (Acti-ubiquinone 50 Cap 50mg)[3] Coenzyme Q-10; Coenzyme Q10; CoQ10--[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
159 Ursodiol 💬
(Actigall (TN))		[1] Ursodeoxycholic acid (Actigall)[4] UDCA; Ursodeoxycholic Acid; Ursodiol; UrsoFalk[1] NR1H4 💬 [1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
160 Valsartan 💬[1] Valsartan (Act Valsartan)[3] Diovan; Entresto; VALSARTAN[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 57, 58, 66, 75, 218, 222, 224 💬
161 Venlafaxine 💬[1] Venlafaxine (Act Venlafaxine XR)[2] Venlafaxine; Venlafaxine Hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46 💬
162 Vitamin A 💬[1] Vitamin A (Acti-retinol & Zn Caplet)[1] Vitamin A[2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90 💬
163 Vitamin E 💬[1] Vitamin E (Acti-D Alphacopherol Cap 400unit)[2] Alpha-tocopherol; Vitamin E--[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
164 Water 💬[1] Water (Activase RT-PA)[8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
165 Zinc acetate 💬[1] Zinc acetate (Action Cream)[2] Wilzin; Zinc acetate--[2] 171, 299 💬
166 Zinc oxide 💬[1] Zinc oxide (SPF 50 plus Sunscreen All Mineral Active Ingredients)[1] Zinc oxide--[1] 156 💬
167 Zoledronic acid 💬[1] Zoledronic acid (Zoledronic Acid Actavis)[4] Aclasta; Zoledronate; ZOLEDRONIC ACID; Zometa[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
168 Zoledronic acid 💬[1] Zoledronic acid (Zoledronic Acid Actavis)[4] ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
169 Zopiclone 💬[1] Zopiclone (Act Zopiclone)[1] Zopiclone[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬