Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Chemical carcinogenesis - receptor activation 💬

[1] VDR 💬

Cholecalciferol 💬

Cholecalciferol

[24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
162	Pemphigoid;
202	Smith-Magenis syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
298	Hereditary pancreatitis;Chronic pancreatitis;
299	Cystic fibrosis;

Circadian entrainment 💬

[2] MTNR1A, MTNR1B 💬

Melatonin 💬

Melatonin

[12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
37	Generalised pustular psoriasis;Pustular psoriasis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
90	Retinitis pigmentosa;
97	Ulcerative colitis;
145	West syndrome;Infantile spasm;
202	Smith-Magenis syndrome;

Circadian entrainment 💬

[2] MTNR1A, MTNR1B 💬

Tasimelteon 💬

Tasimelteon

[1] 202 💬

Endocrine and other factor-regulated calcium reabsorption 💬

[1] VDR 💬

Cholecalciferol 💬

Cholecalciferol

[24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
162	Pemphigoid;
202	Smith-Magenis syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
298	Hereditary pancreatitis;Chronic pancreatitis;
299	Cystic fibrosis;

Mineral absorption 💬

[1] VDR 💬

Cholecalciferol 💬

Cholecalciferol

[24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
162	Pemphigoid;
202	Smith-Magenis syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
298	Hereditary pancreatitis;Chronic pancreatitis;
299	Cystic fibrosis;

Neuroactive ligand-receptor interaction 💬

[1] MC4R 💬

Setmelanotide 💬

Setmelanotide

[2] 202, 265 💬

Neuroactive ligand-receptor interaction 💬

[2] MTNR1A, MTNR1B 💬

Melatonin 💬

Melatonin

[12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
37	Generalised pustular psoriasis;Pustular psoriasis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
90	Retinitis pigmentosa;
97	Ulcerative colitis;
145	West syndrome;Infantile spasm;
202	Smith-Magenis syndrome;

Neuroactive ligand-receptor interaction 💬

[2] MTNR1A, MTNR1B 💬

Tasimelteon 💬

Tasimelteon

[1] 202 💬

Parathyroid hormone synthesis, secretion and action 💬

[1] VDR 💬

Cholecalciferol 💬

Cholecalciferol

[24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
162	Pemphigoid;
202	Smith-Magenis syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
298	Hereditary pancreatitis;Chronic pancreatitis;
299	Cystic fibrosis;

Tuberculosis 💬

[1] VDR 💬

Cholecalciferol 💬

Cholecalciferol

[24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
20	Adrenoleukodystrophy;ALD;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
56	Behcet disease;Behçet disease;BD;
60	Aplastic anemia;
65	Primary immunodeficiency;
84	Sarcoidosis;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
162	Pemphigoid;
202	Smith-Magenis syndrome;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
298	Hereditary pancreatitis;Chronic pancreatitis;
299	Cystic fibrosis;