Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | 
|---|---|---|---|---|---|
| 1 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases  | 
ADORA2B [1] ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 2 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases  | 
ADORA2B [1] ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 3 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases  | 
PDE2A [1] PDE2A 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 4 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases  | 
PDE2A [1] PDE2A 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 5 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 6 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 7 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 8 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
ADORA2B [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 9 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 10 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 11 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 12 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
ADORA1 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 13 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases  | 
PDE8A [2] PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 14 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases  | 
PDE8A [2] PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 15 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
PDE11A [3] PDE11A, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 16 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
PDE11A [3] PDE11A, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 17 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 18 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 19 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 20 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 21 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 22 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 23 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases  | 
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 24 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases  | 
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 25 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
ADORA1 [2] ADORA1, ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 26 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
ADORA1 [2] ADORA1, ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 27 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases  | 
PDE1A [4] PDE1A, PDE1B, PDE1C, PDE2A 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 28 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases  | 
PDE1A [4] PDE1A, PDE1B, PDE1C, PDE2A 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 29 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases  | 
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 30 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases  | 
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 31 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 32 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 33 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 34 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 35 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
ADORA2B [1] ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 36 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
ADORA2B [1] ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 37 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
ADORA1 [2] ADORA1, PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 38 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
ADORA1 [2] ADORA1, PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 39 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
ADORA1 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 40 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
ADORA1 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 41 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases  | 
ADORA1 [1] ADORA1 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 42 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases  | 
ADORA1 [1] ADORA1 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 43 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases  | 
PDE1A [3] PDE1A, PDE1B, PDE1C 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 44 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases  | 
PDE1A [3] PDE1A, PDE1B, PDE1C 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 45 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
ADORA2B [1] ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 | 
| 46 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
ADORA2B [1] ADORA2B 💬
 | 
Theophylline  Theophylline  💬
 | Theophylline | 236 [2] 236, 299 💬
 |