Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 19 diseases |
CPS1 [1] CPS1 💬
|
Carglumic acid Carglumic acid 💬
| Carglumic acid | 245 [3] 245, 246, 251 💬
|
| 2 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A [1] PDE2A 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 3 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B [1] PDE3B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 4 | Arginine biosynthesis 💬 1 gene, 1 drug (DrugBank) and 3 diseases |
CPS1 [1] CPS1 💬
|
Carglumic acid Carglumic acid 💬
| Carglumic acid | 245 [3] 245, 246, 251 💬
|
| 5 | Biosynthesis of amino acids 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 [1] CPS1 💬
|
Carglumic acid Carglumic acid 💬
| Carglumic acid | 245 [3] 245, 246, 251 💬
|
| 6 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 7 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 8 | Carbon metabolism 💬 2 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 [1] CPS1 💬
|
Carglumic acid Carglumic acid 💬
| Carglumic acid | 245 [3] 245, 246, 251 💬
|
| 9 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE2A [3] PDE2A, PDE3A, PDE3B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 10 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A [2] PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 11 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
PDE11A [3] PDE11A, PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 12 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B [1] PDE3B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 13 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B [1] PDE3B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 14 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CPS1 [1] CPS1 💬
|
Carglumic acid Carglumic acid 💬
| Carglumic acid | 245 [3] 245, 246, 251 💬
|
| 15 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 16 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 17 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases |
CPS1 [1] CPS1 💬
|
Carglumic acid Carglumic acid 💬
| Carglumic acid | 245 [3] 245, 246, 251 💬
|
| 18 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1A [4] PDE1A, PDE1B, PDE1C, PDE2A 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 19 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 20 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B [1] PDE3B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 21 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 22 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PDE3B [1] PDE3B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 23 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PDE1A [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 24 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1A [3] PDE1A, PDE1B, PDE1C 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|