Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
2 Adipocytokine signaling pathway 💬
 [3] CPT1A, CPT1B, CPT1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
4 Alcoholic liver disease 💬
 [3] CPT1A, CPT1B, CPT1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
5 Aldosterone synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
6 Alzheimer disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
7 Amphetamine addiction 💬
 [2] CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
8 AMPK signaling pathway 💬
 [3] CPT1A, CPT1B, CPT1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
9 Arrhythmogenic right ventricular cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
10 Axon guidance 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
11 Bacterial invasion of epithelial cells 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
12 Bladder cancer 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
13 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
14 Calcium signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
15 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
16 Carbohydrate digestion and absorption 💬
 [1] CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
17 Cardiac muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
18 Cell cycle 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
19 Cellular senescence 💬
 [1] CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
20 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
21 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
22 Chemical carcinogenesis - receptor activation 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
23 Chemical carcinogenesis - receptor activation 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
24 Chemokine signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
25 Cholinergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
26 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
27 Circadian entrainment 💬
 [2] CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
28 Cortisol synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
29 Cushing syndrome 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
30 Diabetic cardiomyopathy 💬
 [2] CPT1B, CPT2 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
31 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
32 Dopaminergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
33 EGFR tyrosine kinase inhibitor resistance 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
34 Endocrine resistance 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
35 Endocytosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
36 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
37 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
38 Estrogen signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
39 Fatty acid degradation 💬
 [4] CPT1A, CPT1B, CPT1C, CPT2 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
40 Fatty acid metabolism 💬
 [4] CPT1A, CPT1B, CPT1C, CPT2 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
41 Fluid shear stress and atherosclerosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
42 Focal adhesion 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
43 GABAergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
44 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
45 GABAergic synapse 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
46 Gap junction 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
47 Glucagon signaling pathway 💬
 [3] CPT1A, CPT1B, CPT1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
48 Glutamatergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
49 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
50 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
51 GnRH signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
52 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
53 Hepatitis B 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
54 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
55 Human cytomegalovirus infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
56 Hypertrophic cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
57 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
58 Insulin resistance 💬
 [2] CPT1A, CPT1B 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
59 Insulin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
60 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
61 Lipid and atherosclerosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
62 Long-term potentiation 💬
 [1] CACNA1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
63 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
64 MicroRNAs in cancer 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
65 Mitophagy - animal 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
66 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
67 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
68 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
69 Neutrophil extracellular trap formation 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
70 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
71 Oxytocin signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
72 Oxytocin signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
73 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
74 Pathways in cancer 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
75 Pathways of neurodegeneration - multiple diseases 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
76 Platelet activation 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
77 PPAR signaling pathway 💬
 [4] CPT1A, CPT1B, CPT1C, CPT2 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
78 Prion disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
79 Prolactin signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
80 Proteoglycans in cancer 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
81 Rap1 signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
82 Ras signaling pathway 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
83 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
84 Relaxin signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
85 Renin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
86 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
87 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
88 Serotonergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
89 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
90 Shigellosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
91 Taste transduction 💬
 [1] CACNA1C 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
92 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
93 Thermogenesis 💬
 [4] CPT1A, CPT1B, CPT1C, CPT2 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
94 Thyroid hormone signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
95 Tight junction 💬
 [1] CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
96 Tight junction 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
97 Tuberculosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
98 Type II diabetes mellitus 💬
 [2] CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
99 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline [2] 58, 272 💬
100 VEGF signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
101 Viral carcinogenesis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
102 Viral myocarditis 💬
 [1] ABL1 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
103 Yersinia infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬

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