Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | 
|---|---|---|---|---|---|
| 1 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 2 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
PDE3A [2] PDE3A, PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 3 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
PDE3A [2] PDE3A, PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 4 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Sildenafil  Sildenafil  💬
 | Sildenafil | 006 [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
 | 
| 5 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Omeprazole  Omeprazole  💬
 | Omeprazole | 006 [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
 | 
| 6 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Omeprazole  Omeprazole  💬
 | Omeprazole | 006 [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
 | 
| 7 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 8 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 9 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Omeprazole  Omeprazole  💬
 | Omeprazole | 006 [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
 | 
| 10 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE3A [2] PDE3A, PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 11 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Sildenafil  Sildenafil  💬
 | Sildenafil | 006 [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
 | 
| 12 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases  | 
PDE3A [2] PDE3A, PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 13 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Omeprazole  Omeprazole  💬
 | Omeprazole | 006 [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
 | 
| 14 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 15 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE3A [2] PDE3A, PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 16 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Sildenafil  Sildenafil  💬
 | Sildenafil | 006 [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
 | 
| 17 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
PDE3B [1] PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 | 
| 18 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
PDE3A [2] PDE3A, PDE3B 💬
 | 
Milrinone  Milrinone  💬
 | Milrinone | 294 [1] 294 💬
 |