Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
2 Acute myeloid leukemia 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
3 Adherens junction 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
4 Adherens junction 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
5 Adipocytokine signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
6 Adipocytokine signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
7 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
12 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
13 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
14 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
15 Adrenergic signaling in cardiomyocytes 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
16 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
17 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
18 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
19 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
20 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
21 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
22 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
23 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
24 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
25 Aldosterone synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
26 Aldosterone synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
27 Aldosterone-regulated sodium reabsorption 💬
 [1] NR3C2 💬 Spironolactone 💬 Spironolactone [8] 46, 58, 67, 86, 113, 210, 218, 225 💬
28 Aldosterone-regulated sodium reabsorption 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
29 Alzheimer disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
30 Alzheimer disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
31 Alzheimer disease 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
32 Alzheimer disease 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
33 Amphetamine addiction 💬
 [2] CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
34 Amphetamine addiction 💬
 [2] CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
35 AMPK signaling pathway 💬
 [1] ADRA1A 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
36 AMPK signaling pathway 💬
 [1] HMGCR 💬 Pravastatin 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
37 AMPK signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
38 AMPK signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
39 AMPK signaling pathway 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
40 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
41 Amyotrophic lateral sclerosis 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
42 Amyotrophic lateral sclerosis 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
43 Apelin signaling pathway 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
44 Apelin signaling pathway 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
45 Apelin signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
46 Apelin signaling pathway 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
47 Apelin signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
48 Apelin signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
49 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
50 Arrhythmogenic right ventricular cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
51 Arrhythmogenic right ventricular cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
52 Autophagy - animal 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
53 Autophagy - animal 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
54 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
55 Autophagy - other 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
56 Autophagy - other 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
57 Axon guidance 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
58 Axon guidance 💬
 [1] EPHB4 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
59 Bacterial invasion of epithelial cells 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
60 beta-Alanine metabolism 💬
 [1] AOC3 💬 Hydralazine 💬 Hydralazine [1] 67 💬
61 Bile secretion 💬
 [1] HMGCR 💬 Pravastatin 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
62 Bile secretion 💬
 [1] NR1H4 💬 Ursodiol 💬 Ursodeoxycholic acid [14]  6 ,  8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
63 Bladder cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
64 Bladder cancer 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
65 Breast cancer 💬
 [3] EGFR, ERBB2, FLT4 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
66 Breast cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
67 Breast cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
68 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
69 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
70 Calcium signaling pathway 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
71 Calcium signaling pathway 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
72 Calcium signaling pathway 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
73 Calcium signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
74 Calcium signaling pathway 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
75 Calcium signaling pathway 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
76 Calcium signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
77 Calcium signaling pathway 💬
 [4] EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
78 cAMP signaling pathway 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
79 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
80 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
81 cAMP signaling pathway 💬
 [3] SSTR1, SSTR2, SSTR5 💬 Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
82 cAMP signaling pathway 💬
 [3] SSTR1, SSTR2, SSTR5 💬 Somatostatin 💬 Somatostatin [2] 67, 78 💬
83 cAMP signaling pathway 💬
 [1] SSTR2 💬 Octreotide 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
84 Carbohydrate digestion and absorption 💬
 [1] CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
85 Carbohydrate digestion and absorption 💬
 [1] CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
86 Carbohydrate digestion and absorption 💬
 [2] TAS1R2, TAS1R3 💬 Aspartame 💬 Aspartame [4]  6 , 13, 67, 86 💬
87 Cardiac muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
88 Cardiac muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
89 Cell cycle 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
90 Cellular senescence 💬
 [1] CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
91 Cellular senescence 💬
 [1] CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
92 Cellular senescence 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
93 Cellular senescence 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
94 Central carbon metabolism in cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
95 Central carbon metabolism in cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
96 Central carbon metabolism in cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
97 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
98 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
99 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
100 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
101 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
102 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
103 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
104 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
105 Chagas disease 💬
 [1] ACE 💬 Imidapril 💬 Imidapril [1] 67 💬
106 Chagas disease 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
107 Chagas disease 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
108 Chagas disease 💬
 [1] ACE 💬 Ramipril 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
109 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
110 Chemical carcinogenesis - reactive oxygen species 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
111 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
112 Chemical carcinogenesis - receptor activation 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
113 Chemical carcinogenesis - receptor activation 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
114 Chemical carcinogenesis - receptor activation 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
115 Chemical carcinogenesis - receptor activation 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
116 Chemical carcinogenesis - receptor activation 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
117 Chemical carcinogenesis - receptor activation 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
118 Chemokine signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
119 Choline metabolism in cancer 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
120 Choline metabolism in cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
121 Choline metabolism in cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
122 Cholinergic synapse 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
123 Cholinergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
124 Chronic myeloid leukemia 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
125 Circadian entrainment 💬
 [2] CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
126 Circadian entrainment 💬
 [2] CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
127 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
128 Colorectal cancer 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
129 Colorectal cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
130 Colorectal cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
131 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 Imidapril 💬 Imidapril [1] 67 💬
132 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
133 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
134 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 Ramipril 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
135 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
136 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
137 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
138 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
139 Coronavirus disease - COVID-19 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
140 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
141 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
142 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
143 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
144 Cortisol synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
145 Cortisol synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
146 Cushing syndrome 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
147 Cushing syndrome 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
148 Cushing syndrome 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
149 Cushing syndrome 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
150 Cushing syndrome 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
151 Cushing syndrome 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
152 Cushing syndrome 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
153 Diabetic cardiomyopathy 💬
 [1] ACE 💬 Imidapril 💬 Imidapril [1] 67 💬
154 Diabetic cardiomyopathy 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
155 Diabetic cardiomyopathy 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
156 Diabetic cardiomyopathy 💬
 [1] ACE 💬 Ramipril 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
157 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
158 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
159 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
160 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
161 Diabetic cardiomyopathy 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
162 Diabetic cardiomyopathy 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
163 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
164 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
165 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
166 Dopaminergic synapse 💬
 [3] CACNA1B, CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
167 Dopaminergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
168 EGFR tyrosine kinase inhibitor resistance 💬
 [3] EGFR, ERBB2, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
169 EGFR tyrosine kinase inhibitor resistance 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
170 EGFR tyrosine kinase inhibitor resistance 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
171 EGFR tyrosine kinase inhibitor resistance 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
172 Endocrine resistance 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
173 Endocrine resistance 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
174 Endocrine resistance 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
175 Endocrine resistance 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
176 Endocytosis 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
177 Endocytosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
178 Endometrial cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
179 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
180 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
181 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
182 ErbB signaling pathway 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
183 ErbB signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
184 ErbB signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
185 Estrogen signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
186 Estrogen signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
187 Fluid shear stress and atherosclerosis 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
188 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
189 Fluid shear stress and atherosclerosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
190 Focal adhesion 💬
 [4] EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
191 Focal adhesion 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
192 FoxO signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
193 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
194 GABAergic synapse 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
195 GABAergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
196 GABAergic synapse 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
197 Gap junction 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
198 Gap junction 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
199 Gap junction 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
200 Gastric acid secretion 💬
 [1] SSTR2 💬 Octreotide 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
201 Gastric acid secretion 💬
 [1] SSTR2 💬 Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
202 Gastric acid secretion 💬
 [1] SSTR2 💬 Somatostatin 💬 Somatostatin [2] 67, 78 💬
203 Gastric cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
204 Gastric cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
205 Gastric cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
206 Glioma 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
207 Glioma 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
208 Glioma 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
209 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
210 Glutamatergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
211 Glutamatergic synapse 💬
 [2] CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
212 Glycine, serine and threonine metabolism 💬
 [1] AOC3 💬 Hydralazine 💬 Hydralazine [1] 67 💬
213 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
214 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
215 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
216 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
217 GnRH signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
218 GnRH signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
219 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
220 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
221 Growth hormone synthesis, secretion and action 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
222 Growth hormone synthesis, secretion and action 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
223 Growth hormone synthesis, secretion and action 💬
 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
224 Growth hormone synthesis, secretion and action 💬
 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Somatostatin 💬 Somatostatin [2] 67, 78 💬
225 Growth hormone synthesis, secretion and action 💬
 [1] SSTR2 💬 Octreotide 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
226 Hepatitis B 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
227 Hepatitis C 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
228 Hepatocellular carcinoma 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
229 Hepatocellular carcinoma 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
230 Hepatocellular carcinoma 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
231 Herpes simplex virus 1 infection 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
232 Herpes simplex virus 1 infection 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
233 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
234 HIF-1 signaling pathway 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
235 HIF-1 signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
236 HIF-1 signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
237 Human cytomegalovirus infection 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
238 Human cytomegalovirus infection 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
239 Human cytomegalovirus infection 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
240 Human cytomegalovirus infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
241 Human immunodeficiency virus 1 infection 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
242 Human immunodeficiency virus 1 infection 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
243 Human papillomavirus infection 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
244 Human papillomavirus infection 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
245 Human papillomavirus infection 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
246 Huntington disease 💬
 [1] CACNA1B 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
247 Huntington disease 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
248 Huntington disease 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
249 Huntington disease 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
250 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 Imidapril 💬 Imidapril [1] 67 💬
251 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
252 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
253 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 Ramipril 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
254 Hypertrophic cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
255 Hypertrophic cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
256 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
257 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
258 Insulin resistance 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
259 Insulin resistance 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
260 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
261 Insulin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
262 Insulin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
263 Insulin signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
264 Insulin signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
265 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
266 JAK-STAT signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
267 JAK-STAT signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
268 JAK-STAT signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
269 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
270 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
271 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
272 Lipid and atherosclerosis 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
273 Lipid and atherosclerosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
274 Long-term potentiation 💬
 [1] CACNA1C 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
275 Long-term potentiation 💬
 [1] CACNA1C 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
276 Longevity regulating pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
277 Longevity regulating pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
278 Longevity regulating pathway 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
279 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
280 Longevity regulating pathway - multiple species 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
281 Longevity regulating pathway - multiple species 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
282 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
283 MAPK signaling pathway 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
284 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
285 MAPK signaling pathway 💬
 [4] EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
286 Melanoma 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
287 Metabolic pathways 💬
 [1] AOC3 💬 Hydralazine 💬 Hydralazine [1] 67 💬
288 Metabolic pathways 💬
 [1] HMGCR 💬 Pravastatin 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
289 Metabolic pathways 💬
 [1] UGCG 💬 Venglustat 💬 Venglustat [3]  6 , 19, 67 💬
290 MicroRNAs in cancer 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
291 MicroRNAs in cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
292 MicroRNAs in cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
293 MicroRNAs in cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
294 Mitophagy - animal 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
295 Morphine addiction 💬
 [1] CACNA1B 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
296 mTOR signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
297 mTOR signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
298 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
299 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
300 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
301 Neuroactive ligand-receptor interaction 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
302 Neuroactive ligand-receptor interaction 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
303 Neuroactive ligand-receptor interaction 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
304 Neuroactive ligand-receptor interaction 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
305 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 Lixivaptan 💬 Lixivaptan [1] 67 💬
306 Neuroactive ligand-receptor interaction 💬
 [1] AVPR2 💬 Tolvaptan 💬 Tolvaptan [4] 67, 72, 86, 225 💬
307 Neuroactive ligand-receptor interaction 💬
 [5] SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 💬 Somatostatin 💬 Somatostatin [2] 67, 78 💬
308 Neuroactive ligand-receptor interaction 💬
 [4] SSTR1, SSTR2, SSTR3, SSTR5 💬 Pasireotide 💬 Pasireotide [3] 67, 74, 75 💬
309 Neuroactive ligand-receptor interaction 💬
 [1] SSTR2 💬 Octreotide 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
310 Neurotrophin signaling pathway 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
311 Neutrophil extracellular trap formation 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
312 Neutrophil extracellular trap formation 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
313 Neutrophil extracellular trap formation 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
314 Nicotine addiction 💬
 [1] CACNA1B 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
315 Non-alcoholic fatty liver disease 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
316 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
317 Non-small cell lung cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
318 Osteoclast differentiation 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
319 Oxytocin signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
320 Oxytocin signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
321 Oxytocin signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
322 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
323 Oxytocin signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
324 Pancreatic cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
325 Pancreatic cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
326 Pancreatic cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
327 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
328 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
329 Pathways in cancer 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
330 Pathways in cancer 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
331 Pathways in cancer 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
332 Pathways in cancer 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
333 Pathways in cancer 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
334 Pathways in cancer 💬
 [3] EGFR, ERBB2, FLT4 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
335 Pathways in cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
336 Pathways in cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
337 Pathways in cancer 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
338 Pathways of neurodegeneration - multiple diseases 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
339 Pathways of neurodegeneration - multiple diseases 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
340 Pathways of neurodegeneration - multiple diseases 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
341 Pathways of neurodegeneration - multiple diseases 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
342 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
343 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
344 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
345 Phenylalanine metabolism 💬
 [1] AOC3 💬 Hydralazine 💬 Hydralazine [1] 67 💬
346 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
347 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
348 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
349 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
350 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 Lixivaptan 💬 Lixivaptan [1] 67 💬
351 Phospholipase D signaling pathway 💬
 [1] AVPR2 💬 Tolvaptan 💬 Tolvaptan [4] 67, 72, 86, 225 💬
352 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
353 Phospholipase D signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
354 Phospholipase D signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
355 PI3K-Akt signaling pathway 💬
 [4] EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
356 PI3K-Akt signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
357 PI3K-Akt signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
358 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
359 Platelet activation 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
360 Platinum drug resistance 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
361 PPAR signaling pathway 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
362 Prion disease 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
363 Prion disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
364 Prolactin signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
365 Prostate cancer 💬
 [2] EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
366 Prostate cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
367 Prostate cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
368 Proteoglycans in cancer 💬
 [3] EGFR, ERBB2, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
369 Proteoglycans in cancer 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
370 Proteoglycans in cancer 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
371 Proteoglycans in cancer 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
372 Rap1 signaling pathway 💬
 [3] EGFR, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
373 Rap1 signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
374 Ras signaling pathway 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
375 Ras signaling pathway 💬
 [3] EGFR, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
376 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
377 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
378 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
379 Relaxin signaling pathway 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
380 Relaxin signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
381 Renin secretion 💬
 [1] ACE 💬 Imidapril 💬 Imidapril [1] 67 💬
382 Renin secretion 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
383 Renin secretion 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
384 Renin secretion 💬
 [1] ACE 💬 Ramipril 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
385 Renin secretion 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
386 Renin secretion 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
387 Renin secretion 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
388 Renin secretion 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
389 Renin secretion 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
390 Renin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
391 Renin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
392 Renin-angiotensin system 💬
 [1] ACE 💬 Imidapril 💬 Imidapril [1] 67 💬
393 Renin-angiotensin system 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
394 Renin-angiotensin system 💬
 [1] ACE 💬 Lisinopril 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
395 Renin-angiotensin system 💬
 [1] ACE 💬 Ramipril 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
396 Renin-angiotensin system 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
397 Renin-angiotensin system 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
398 Renin-angiotensin system 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
399 Renin-angiotensin system 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
400 Retrograde endocannabinoid signaling 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
401 Retrograde endocannabinoid signaling 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
402 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
403 Salivary secretion 💬
 [1] ADRB1 💬 Bisoprolol 💬 Bisoprolol [4] 58, 67, 86, 113 💬
404 Serotonergic synapse 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
405 Serotonergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
406 Shigellosis 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
407 Shigellosis 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
408 Shigellosis 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
409 Shigellosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
410 Sphingolipid metabolism 💬
 [1] UGCG 💬 Venglustat 💬 Venglustat [3]  6 , 19, 67 💬
411 Spinocerebellar ataxia 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
412 Spinocerebellar ataxia 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
413 Synaptic vesicle cycle 💬
 [1] CACNA1B 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
414 Taste transduction 💬
 [1] CACNA1C 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
415 Taste transduction 💬
 [1] CACNA1C 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
416 Taste transduction 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
417 Taste transduction 💬
 [2] TAS1R2, TAS1R3 💬 Aspartame 💬 Aspartame [4]  6 , 13, 67, 86 💬
418 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 Pravastatin 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
419 Th17 cell differentiation 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
420 Th17 cell differentiation 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
421 Thermogenesis 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
422 Thermogenesis 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
423 Thermogenesis 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
424 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
425 Thyroid cancer 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
426 Thyroid hormone signaling pathway 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
427 Thyroid hormone signaling pathway 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
428 Thyroid hormone signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
429 Tight junction 💬
 [1] CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
430 Tight junction 💬
 [1] CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
431 Tight junction 💬
 [1] ERBB2 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
432 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
433 Tight junction 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
434 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
435 Tuberculosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
436 Type II diabetes mellitus 💬
 [3] CACNA1B, CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
437 Type II diabetes mellitus 💬
 [2] CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
438 Type II diabetes mellitus 💬
 [1] MTOR 💬 Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
439 Type II diabetes mellitus 💬
 [1] MTOR 💬 Sirolimus 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
440 Tyrosine metabolism 💬
 [1] AOC3 💬 Hydralazine 💬 Hydralazine [1] 67 💬
441 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin [2] 57, 67 💬
442 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Candesartan 💬 Candesartan [2] 58, 67 💬
443 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil [1] 67 💬
444 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
445 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Telmisartan 💬 Telmisartan [2] 66, 67 💬
446 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
447 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine [1] 67 💬
448 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 Lixivaptan 💬 Lixivaptan [1] 67 💬
449 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 Tolvaptan 💬 Tolvaptan [4] 67, 72, 86, 225 💬
450 VEGF signaling pathway 💬
 [1] KDR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
451 VEGF signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
452 Viral carcinogenesis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
453 Viral myocarditis 💬
 [1] ABL1 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
454 Yersinia infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬

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