Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Calcium signaling pathway 💬

[1] OXTR 💬

Oxytocin 💬

Oxytocin

[7] 6 , 72, 127, 168, 193, 206, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
127	Frontotemporal lobar degeneration;
168	Ehlers-Danlos syndrome;EDS;
193	Prader-Willi syndrome;
206	Fragile X syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

cAMP signaling pathway 💬

[1] GLP1R 💬

Exenatide 💬

Exenatide

[6] 6 , 17, 72, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

cAMP signaling pathway 💬

[1] OXTR 💬

Oxytocin 💬

Oxytocin

[7] 6 , 72, 127, 168, 193, 206, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
127	Frontotemporal lobar degeneration;
168	Ehlers-Danlos syndrome;EDS;
193	Prader-Willi syndrome;
206	Fragile X syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Circadian entrainment 💬

[2] MTNR1A, MTNR1B 💬

Melatonin 💬

Melatonin

[12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
37	Generalised pustular psoriasis;Pustular psoriasis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
90	Retinitis pigmentosa;
97	Ulcerative colitis;
145	West syndrome;Infantile spasm;
202	Smith-Magenis syndrome;

Complement and coagulation cascades 💬

[1] F8 💬

Desmopressin 💬

Desmopressin

[6] 6 , 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
64	Thrombotic thrombocytopenic purpura;TTP;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
75	Cushing disease;Cushing;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
288	Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;

Insulin secretion 💬

[1] GLP1R 💬

Exenatide 💬

Exenatide

[6] 6 , 17, 72, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

Neuroactive ligand-receptor interaction 💬

[1] AVPR2 💬

Desmopressin 💬

Desmopressin

[6] 6 , 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
64	Thrombotic thrombocytopenic purpura;TTP;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
75	Cushing disease;Cushing;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
288	Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;

Neuroactive ligand-receptor interaction 💬

[1] AVPR2 💬

Tolvaptan 💬

Tolvaptan

[4] 67, 72, 86, 225 💬

Disease ID	Name
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
86	Pulmonary arterial hypertension;PAH;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;

Neuroactive ligand-receptor interaction 💬

[1] GLP1R 💬

Exenatide 💬

Exenatide

[6] 6 , 17, 72, 78, 193, 233 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
193	Prader-Willi syndrome;
233	Wolfram syndrome;Diabetes Insipidus, Diabetes mellitus, optic atrophy, and deafness syndrome;DIDMOAD syndrome;

Neuroactive ligand-receptor interaction 💬

[2] MTNR1A, MTNR1B 💬

Melatonin 💬

Melatonin

[12] 6 , 8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
8	Huntington disease;Huntington chorea;
13	Multiple sclerosis/Neuromyelitis optica;
37	Generalised pustular psoriasis;Pustular psoriasis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
90	Retinitis pigmentosa;
97	Ulcerative colitis;
145	West syndrome;Infantile spasm;
202	Smith-Magenis syndrome;

Neuroactive ligand-receptor interaction 💬

[1] OXTR 💬

Oxytocin 💬

Oxytocin

[7] 6 , 72, 127, 168, 193, 206, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
127	Frontotemporal lobar degeneration;
168	Ehlers-Danlos syndrome;EDS;
193	Prader-Willi syndrome;
206	Fragile X syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Oxytocin signaling pathway 💬

[1] OXTR 💬

Oxytocin 💬

Oxytocin

[7] 6 , 72, 127, 168, 193, 206, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
127	Frontotemporal lobar degeneration;
168	Ehlers-Danlos syndrome;EDS;
193	Prader-Willi syndrome;
206	Fragile X syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Phospholipase D signaling pathway 💬

[1] AVPR2 💬

Desmopressin 💬

Desmopressin

[6] 6 , 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
64	Thrombotic thrombocytopenic purpura;TTP;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
75	Cushing disease;Cushing;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
288	Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;

Phospholipase D signaling pathway 💬

[1] AVPR2 💬

Tolvaptan 💬

Tolvaptan

[4] 67, 72, 86, 225 💬

Disease ID	Name
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
86	Pulmonary arterial hypertension;PAH;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;

Vasopressin-regulated water reabsorption 💬

[1] AVPR2 💬

Desmopressin 💬

Desmopressin

[6] 6 , 64, 72, 75, 225, 288 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
64	Thrombotic thrombocytopenic purpura;TTP;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
75	Cushing disease;Cushing;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;
288	Autoimmune acquired coagulation factor deficiency;Coagulation factor deficiency;

Vasopressin-regulated water reabsorption 💬

[1] AVPR2 💬

Tolvaptan 💬

Tolvaptan

[4] 67, 72, 86, 225 💬

Disease ID	Name
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
72	Pituitary ADH secretion disorder;Inappropriate antidiuretic hormone secretion;Syndrome of inappropriate secretion of antidiuretic hormone;Inappropriate ADH syndrome;Syndrome of inappropriate ADH;
86	Pulmonary arterial hypertension;PAH;
225	Congenital nephrogenic diabetes insipidus;Hereditary nephrogenic diabetes insipidus;Nephrogenic diabetes insipidus;