Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | 
|---|---|---|---|---|---|
| 1 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 2 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
PGR [1] PGR 💬
 | 
Megestrol acetate  Megestrol acetate  💬
 | Megestrol acetate | 076 [1] 76 💬
 | 
| 3 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
PGR [1] PGR 💬
 | 
Progesterone  Progesterone  💬
 | Progesterone | 076 [2] 76, 299 💬
 | 
| 4 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
AR [1] AR 💬
 | 
Testosterone  Testosterone  💬
 | Testosterone | 001 [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
 | 
| 5 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 6 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
PGR [1] PGR 💬
 | 
Megestrol acetate  Megestrol acetate  💬
 | Megestrol acetate | 076 [1] 76 💬
 | 
| 7 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
PGR [1] PGR 💬
 | 
Progesterone  Progesterone  💬
 | Progesterone | 076 [2] 76, 299 💬
 | 
| 8 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 9 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 10 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 11 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
PGR [1] PGR 💬
 | 
Megestrol acetate  Megestrol acetate  💬
 | Megestrol acetate | 076 [1] 76 💬
 | 
| 12 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
PGR [1] PGR 💬
 | 
Progesterone  Progesterone  💬
 | Progesterone | 076 [2] 76, 299 💬
 | 
| 13 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases  | 
ESR2 [1] ESR2 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 14 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases  | 
GNRHR [1] GNRHR 💬
 | 
Gonadorelin  Gonadorelin  💬
 | Gonadorelin | 076 [1] 76 💬
 | 
| 15 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases  | 
GNRHR [1] GNRHR 💬
 | 
Histrelin  Histrelin  💬
 | Histrelin | 076 [1] 76 💬
 | 
| 16 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases  | 
GNRHR [1] GNRHR 💬
 | 
Triptorelin  Triptorelin  💬
 | Triptorelin | 049 [2] 49, 76 💬
 | 
| 17 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
GNRHR [1] GNRHR 💬
 | 
Gonadorelin  Gonadorelin  💬
 | Gonadorelin | 076 [1] 76 💬
 | 
| 18 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
GNRHR [1] GNRHR 💬
 | 
Histrelin  Histrelin  💬
 | Histrelin | 076 [1] 76 💬
 | 
| 19 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
GNRHR [1] GNRHR 💬
 | 
Triptorelin  Triptorelin  💬
 | Triptorelin | 049 [2] 49, 76 💬
 | 
| 20 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases  | 
AR [1] AR 💬
 | 
Testosterone  Testosterone  💬
 | Testosterone | 001 [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
 | 
| 21 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases  | 
PGR [1] PGR 💬
 | 
Megestrol acetate  Megestrol acetate  💬
 | Megestrol acetate | 076 [1] 76 💬
 | 
| 22 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases  | 
PGR [1] PGR 💬
 | 
Progesterone  Progesterone  💬
 | Progesterone | 076 [2] 76, 299 💬
 | 
| 23 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
AR [1] AR 💬
 | 
Testosterone  Testosterone  💬
 | Testosterone | 001 [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
 | 
| 24 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 25 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases  | 
PGR [1] PGR 💬
 | 
Megestrol acetate  Megestrol acetate  💬
 | Megestrol acetate | 076 [1] 76 💬
 | 
| 26 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases  | 
PGR [1] PGR 💬
 | 
Progesterone  Progesterone  💬
 | Progesterone | 076 [2] 76, 299 💬
 | 
| 27 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 28 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
AR [1] AR 💬
 | 
Testosterone  Testosterone  💬
 | Testosterone | 001 [8]  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬
 | 
| 29 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 | 
| 30 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases  | 
ESR1 [1] ESR1 💬
 | 
Estradiol  Estradiol  💬
 | Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬
 |