Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | 
|---|---|---|---|---|---|
| 1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases  | 
BRAF [4] BRAF, FLT3, KIT, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases  | 
KIT [1] KIT 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases  | 
KIT [1] KIT 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 4 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 5 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 6 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 7 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 8 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 9 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 10 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 11 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 12 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
AGTR1 [2] AGTR1, AGTR2 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 13 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
AGTR1 [2] AGTR1, AGTR2 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 14 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 15 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 16 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
SCN5A [1] SCN5A 💬
 | 
Lidocaine  Lidocaine  💬
 | Lidocaine | 006 [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
 | 
| 17 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases  | 
SCN5A [1] SCN5A 💬
 | 
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬
 | Lidocaine | 006 [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
 | 
| 18 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 19 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 20 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 21 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 22 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 23 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases  | 
DRD2 [1] DRD2 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 24 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases  | 
DRD2 [1] DRD2 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 25 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 26 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 27 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 28 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 29 | Aldosterone-regulated sodium reabsorption 💬 13 genes, 14 drugs (DrugBank) and 25 diseases  | 
NR3C2 [1] NR3C2 💬
 | 
Spironolactone  Spironolactone  💬
 | Spironolactone | 046 [8] 46, 58, 67, 86, 113, 210, 218, 225 💬
 | 
| 30 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 31 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 32 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 33 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 34 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 35 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 36 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 37 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases  | 
IL1R1 [2] IL1R1, IL1R2 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 38 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 39 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 40 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases  | 
ADRA1A [1] ADRA1A 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 41 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases  | 
HMGCR [1] HMGCR 💬
 | 
Simvastatin  Simvastatin  💬
 | Simvastatin | 006 [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
 | 
| 42 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 43 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 44 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 45 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 46 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 47 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 48 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 49 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 50 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 51 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 52 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 53 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases  | 
PARP1 [2] PARP1, PARP2 💬
 | 
Olaparib  Olaparib  💬
 | Olaparib | 086 [2] 86, 285 💬
 | 
| 54 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 55 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 56 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 57 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 58 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 59 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 60 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 61 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 62 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 63 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 64 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 65 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 66 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 67 | Base excision repair 💬 2 genes, 1 drug (DrugBank) and 2 diseases  | 
PARP1 [2] PARP1, PARP2 💬
 | 
Olaparib  Olaparib  💬
 | Olaparib | 086 [2] 86, 285 💬
 | 
| 68 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases  | 
CA2 [1] CA2 💬
 | 
Acetazolamide  Acetazolamide  💬
 | Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
 | 
| 69 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases  | 
HMGCR [1] HMGCR 💬
 | 
Simvastatin  Simvastatin  💬
 | Simvastatin | 006 [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
 | 
| 70 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases  | 
NQO1 [2] NQO1, VKORC1 💬
 | 
Warfarin  Warfarin  💬
 | Warfarin | 006 [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 | 
| 71 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 72 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 73 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
BRAF [4] BRAF, FLT4, KIT, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 74 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 75 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 76 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 77 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
KIT [1] KIT 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 78 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
KIT [1] KIT 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 79 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 80 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 81 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 82 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 83 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 84 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 85 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 86 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 87 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 88 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 89 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
AVPR1A [1] AVPR1A 💬
 | 
Conivaptan  Conivaptan  💬
 | Conivaptan | 086 [1] 86 💬
 | 
| 90 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 91 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 92 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Ambrisentan  Ambrisentan  💬
 | Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
 | 
| 93 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Sitaxentan  Sitaxentan  💬
 | Sitaxentan | 086 [1] 86 💬
 | 
| 94 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 95 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 96 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 97 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 98 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 99 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
HRH1 [1] HRH1 💬
 | 
Diphenhydramine  Diphenhydramine  💬
 | Diphenhydramine | 011 [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
 | 
| 100 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
HRH2 [1] HRH2 💬
 | 
Famotidine  Famotidine  💬
 | Famotidine | 006 [6]  6 , 46, 61, 86, 98, 107 💬
 | 
| 101 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 102 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 103 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 104 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 105 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
ADRB1 [2] ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 106 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 107 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 108 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 109 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 110 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
DRD2 [1] DRD2 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 111 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
DRD2 [1] DRD2 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 112 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Ambrisentan  Ambrisentan  💬
 | Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
 | 
| 113 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 114 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 115 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 116 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Sitaxentan  Sitaxentan  💬
 | Sitaxentan | 086 [1] 86 💬
 | 
| 117 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases  | 
CACNA1D [1] CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 118 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases  | 
CACNA1D [1] CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 119 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases  | 
TAS1R2 [2] TAS1R2, TAS1R3 💬
 | 
Aspartame  Aspartame  💬
 | Aspartame | 006 [4]  6 , 13, 67, 86 💬
 | 
| 120 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 121 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 122 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 123 | Cell cycle 💬 10 genes, 9 drugs (DrugBank) and 21 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 124 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases  | 
CACNA1D [1] CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 125 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases  | 
CACNA1D [1] CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 126 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 127 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 128 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 129 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases  | 
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 130 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases  | 
KIT [2] KIT, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 131 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases  | 
KIT [3] KIT, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 132 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 133 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 134 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 135 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 136 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 137 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 138 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 139 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 140 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 141 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Ambrisentan  Ambrisentan  💬
 | Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
 | 
| 142 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Sitaxentan  Sitaxentan  💬
 | Sitaxentan | 086 [1] 86 💬
 | 
| 143 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 144 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 145 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 146 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 147 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Sildenafil  Sildenafil  💬
 | Sildenafil | 006 [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
 | 
| 148 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Tadalafil  Tadalafil  💬
 | Tadalafil | 006 [7]  6 , 51, 75, 84, 86, 113, 210 💬
 | 
| 149 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Udenafil  Udenafil  💬
 | Udenafil | 086 [2] 86, 210 💬
 | 
| 150 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Vardenafil  Vardenafil  💬
 | Vardenafil | 013 [3] 13, 86, 299 💬
 | 
| 151 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 152 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases  | 
ACE [1] ACE 💬
 | 
Captopril  Captopril  💬
 | Captopril | 006 [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
 | 
| 153 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 154 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 155 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 156 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 157 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 158 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 159 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases  | 
KEAP1 [1] KEAP1 💬
 | 
Dimethyl fumarate  Dimethyl fumarate  💬
 | Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬
 | 
| 160 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 161 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases  | 
NQO1 [1] NQO1 💬
 | 
Warfarin  Warfarin  💬
 | Warfarin | 006 [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 | 
| 162 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 163 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 164 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
ADRB1 [2] ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 165 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 166 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
AR [3] AR, ESR1, ESR2 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 167 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 168 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 169 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 170 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 171 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 172 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 173 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 174 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 175 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 176 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 177 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 178 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases  | 
PDGFRB [2] PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 179 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 180 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 181 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 182 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 183 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 184 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 185 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 186 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 187 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 25 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 188 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases  | 
DRD2 [1] DRD2 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 189 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases  | 
DRD2 [1] DRD2 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 190 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Esomeprazole  Esomeprazole  💬
 | Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
 | 
| 191 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases  | 
CA2 [1] CA2 💬
 | 
Acetazolamide  Acetazolamide  💬
 | Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
 | 
| 192 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 193 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 194 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 195 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases  | 
ACE [1] ACE 💬
 | 
Captopril  Captopril  💬
 | Captopril | 006 [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
 | 
| 196 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 197 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 198 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 199 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 200 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 201 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 202 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 203 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 204 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 205 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 206 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 207 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
BRAF [1] BRAF 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 208 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 209 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 210 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 211 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases  | 
ACVR2A [1] ACVR2A 💬
 | 
Sotatercept  Sotatercept  💬
 | Sotatercept | 086 [2] 86, 284 💬
 | 
| 212 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases  | 
IL1R1 [2] IL1R1, IL1R2 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 213 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 214 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 215 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases  | 
PRL [1] PRL 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 216 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases  | 
ACE [1] ACE 💬
 | 
Captopril  Captopril  💬
 | Captopril | 006 [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
 | 
| 217 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 218 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 219 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 220 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases  | 
PARP1 [1] PARP1 💬
 | 
Olaparib  Olaparib  💬
 | Olaparib | 086 [2] 86, 285 💬
 | 
| 221 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases  | 
PDK2 [3] PDK2, PDK3, PDK4 💬
 | 
Sodium dichloroacetate  Sodium dichloroacetate  💬
 | Sodium dichloroacetate | 086 [1] 86 💬
 | 
| 222 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 223 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 224 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 225 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 226 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 227 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 228 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 229 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases  | 
DRD2 [1] DRD2 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 230 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases  | 
DRD2 [3] DRD2, DRD3, DRD4 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 231 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases  | 
SCN1A [1] SCN1A 💬
 | 
Lidocaine  Lidocaine  💬
 | Lidocaine | 006 [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
 | 
| 232 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases  | 
SCN1A [1] SCN1A 💬
 | 
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬
 | Lidocaine | 006 [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
 | 
| 233 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases  | 
RRM2 [1] RRM2 💬
 | 
Hydroxyurea  Hydroxyurea  💬
 | Hydroxyurea | 003 [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 234 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases  | 
BRAF [4] BRAF, KDR, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 235 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 236 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 237 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 238 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 239 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 240 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 241 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases  | 
ESR1 [1] ESR1 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 242 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases  | 
ESR1 [1] ESR1 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 243 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 244 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 245 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 246 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 247 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 248 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 249 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 250 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 251 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 252 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 253 | Epithelial cell signaling in Helicobacter pylori infection 💬 12 genes, 17 drugs (DrugBank) and 21 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 254 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 255 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 256 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 257 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 258 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 259 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 260 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 261 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 262 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
OPRM1 [1] OPRM1 💬
 | 
Morphine  Morphine  💬
 | Morphine | 036 [5] 36, 46, 70, 85, 86 💬
 | 
| 263 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 264 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 265 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 266 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases  | 
ACVR2A [1] ACVR2A 💬
 | 
Sotatercept  Sotatercept  💬
 | Sotatercept | 086 [2] 86, 284 💬
 | 
| 267 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases  | 
IL1R1 [2] IL1R1, IL1R2 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 268 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases  | 
KDR [1] KDR 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 269 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases  | 
KEAP1 [1] KEAP1 💬
 | 
Dimethyl fumarate  Dimethyl fumarate  💬
 | Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬
 | 
| 270 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 271 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases  | 
NQO1 [1] NQO1 💬
 | 
Warfarin  Warfarin  💬
 | Warfarin | 006 [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 | 
| 272 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 273 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases  | 
BRAF [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 274 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 275 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 276 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 277 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 278 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 279 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 280 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 281 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 282 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 283 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 284 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 285 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
DRD2 [1] DRD2 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 286 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
DRD2 [1] DRD2 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 287 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 288 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 289 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 290 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 291 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases  | 
PDGFRB [2] PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 292 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Esomeprazole  Esomeprazole  💬
 | Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
 | 
| 293 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases  | 
CA2 [1] CA2 💬
 | 
Acetazolamide  Acetazolamide  💬
 | Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
 | 
| 294 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases  | 
HRH2 [1] HRH2 💬
 | 
Famotidine  Famotidine  💬
 | Famotidine | 006 [6]  6 , 46, 61, 86, 98, 107 💬
 | 
| 295 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 296 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 297 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 298 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases  | 
BRAF [3] BRAF, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 299 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 300 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 301 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 302 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 303 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 304 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 305 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 306 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases  | 
ANPEP [1] ANPEP 💬
 | 
Ubenimex  Ubenimex  💬
 | Ubenimex | 086 [1] 86 💬
 | 
| 307 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases  | 
RRM2 [1] RRM2 💬
 | 
Hydroxyurea  Hydroxyurea  💬
 | Hydroxyurea | 003 [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 308 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 309 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 310 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases  | 
ESR2 [1] ESR2 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 311 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases  | 
ESR2 [1] ESR2 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 312 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 313 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 314 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 315 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 316 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 317 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 318 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 319 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 320 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 321 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
ANPEP [1] ANPEP 💬
 | 
Ubenimex  Ubenimex  💬
 | Ubenimex | 086 [1] 86 💬
 | 
| 322 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
FLT3 [2] FLT3, KIT 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 323 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
IL1R1 [2] IL1R1, IL1R2 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 324 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 325 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 326 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
KIT [1] KIT 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 327 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
KIT [1] KIT 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 328 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases  | 
MS4A1 [1] MS4A1 💬
 | 
Rituximab  Rituximab  💬
 | Rituximab | 011 [48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
 | 
| 329 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 330 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 331 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 332 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 333 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 334 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases  | 
KEAP1 [1] KEAP1 💬
 | 
Dimethyl fumarate  Dimethyl fumarate  💬
 | Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬
 | 
| 335 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 336 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases  | 
NQO1 [1] NQO1 💬
 | 
Warfarin  Warfarin  💬
 | Warfarin | 006 [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 | 
| 337 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 338 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 339 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 340 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 341 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 342 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 343 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 344 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 345 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 346 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 347 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 348 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 349 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 350 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 351 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 352 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 353 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 354 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 355 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 356 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases  | 
PDGFRB [1] PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 357 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases  | 
PDGFRB [2] PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 358 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 359 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 360 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases  | 
IL1R1 [2] IL1R1, IL1R2 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 361 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 362 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 363 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 364 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases  | 
ACE [1] ACE 💬
 | 
Captopril  Captopril  💬
 | Captopril | 006 [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
 | 
| 365 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 366 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 367 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 368 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 369 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 370 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases  | 
HRH1 [1] HRH1 💬
 | 
Diphenhydramine  Diphenhydramine  💬
 | Diphenhydramine | 011 [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
 | 
| 371 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 372 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases  | 
TRPV1 [1] TRPV1 💬
 | 
Capsaicin  Capsaicin  💬
 | Capsaicin | 006 [3]  6 , 86, 226 💬
 | 
| 373 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 374 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 375 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 376 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 377 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 378 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 379 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 380 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 381 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 382 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 383 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 384 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 385 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 386 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 387 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
PDGFRB [2] PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 388 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases  | 
PRL [1] PRL 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 389 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 390 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 391 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 392 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 393 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 394 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 395 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 396 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 397 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 398 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 399 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 400 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases  | 
CACNA1C [1] CACNA1C 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 401 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases  | 
CACNA1C [1] CACNA1C 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 402 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 403 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 404 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 405 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 406 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 407 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 408 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 409 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 410 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 411 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 412 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
KIT [2] KIT, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 413 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
KIT [3] KIT, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 414 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 415 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases  | 
EDNRB [1] EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 416 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases  | 
EDNRB [1] EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 417 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases  | 
EDNRB [1] EDNRB 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 418 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases  | 
KIT [1] KIT 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 419 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases  | 
KIT [1] KIT 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 420 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases  | 
KIT [2] KIT, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 421 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases  | 
BRAF [3] BRAF, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 422 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 423 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 424 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 425 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
ANPEP [1] ANPEP 💬
 | 
Ubenimex  Ubenimex  💬
 | Ubenimex | 086 [1] 86 💬
 | 
| 426 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Esomeprazole  Esomeprazole  💬
 | Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
 | 
| 427 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬
 | 
Acetazolamide  Acetazolamide  💬
 | Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
 | 
| 428 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
CYP19A1 [1] CYP19A1 💬
 | 
Anastrozole  Anastrozole  💬
 | Anastrozole | 078 [3] 78, 86, 193 💬
 | 
| 429 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 430 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
HMGCR [1] HMGCR 💬
 | 
Simvastatin  Simvastatin  💬
 | Simvastatin | 006 [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
 | 
| 431 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
NQO1 [2] NQO1, VKORC1 💬
 | 
Warfarin  Warfarin  💬
 | Warfarin | 006 [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 | 
| 432 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Sildenafil  Sildenafil  💬
 | Sildenafil | 006 [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
 | 
| 433 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Tadalafil  Tadalafil  💬
 | Tadalafil | 006 [7]  6 , 51, 75, 84, 86, 113, 210 💬
 | 
| 434 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Udenafil  Udenafil  💬
 | Udenafil | 086 [2] 86, 210 💬
 | 
| 435 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Vardenafil  Vardenafil  💬
 | Vardenafil | 013 [3] 13, 86, 299 💬
 | 
| 436 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 437 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 438 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases  | 
RRM2 [1] RRM2 💬
 | 
Hydroxyurea  Hydroxyurea  💬
 | Hydroxyurea | 003 [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 439 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases  | 
ABL1 [2] ABL1, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 440 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases  | 
ABL1 [3] ABL1, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 441 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 442 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 443 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases  | 
PDGFRB [2] PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 444 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 445 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 446 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases  | 
OPRM1 [1] OPRM1 💬
 | 
Morphine  Morphine  💬
 | Morphine | 036 [5] 36, 46, 70, 85, 86 💬
 | 
| 447 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 448 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 449 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 450 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 451 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases  | 
PARP1 [1] PARP1 💬
 | 
Olaparib  Olaparib  💬
 | Olaparib | 086 [2] 86, 285 💬
 | 
| 452 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 453 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 454 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 455 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 456 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
AGTR1 [2] AGTR1, AGTR2 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 457 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
AGTR1 [2] AGTR1, AGTR2 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 458 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
AVPR1A [2] AVPR1A, AVPR2 💬
 | 
Conivaptan  Conivaptan  💬
 | Conivaptan | 086 [1] 86 💬
 | 
| 459 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
AVPR2 [1] AVPR2 💬
 | 
Tolvaptan  Tolvaptan  💬
 | Tolvaptan | 067 [4] 67, 72, 86, 225 💬
 | 
| 460 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
DRD2 [3] DRD2, DRD3, DRD4 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 461 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
DRD2 [2] DRD2, PRL 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 462 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Ambrisentan  Ambrisentan  💬
 | Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
 | 
| 463 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Sitaxentan  Sitaxentan  💬
 | Sitaxentan | 086 [1] 86 💬
 | 
| 464 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 465 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 466 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 467 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
HRH1 [1] HRH1 💬
 | 
Diphenhydramine  Diphenhydramine  💬
 | Diphenhydramine | 011 [8] 11, 13, 49, 51, 70, 86, 222, 256 💬
 | 
| 468 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
HRH2 [1] HRH2 💬
 | 
Famotidine  Famotidine  💬
 | Famotidine | 006 [6]  6 , 46, 61, 86, 98, 107 💬
 | 
| 469 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
NR3C1 [1] NR3C1 💬
 | 
Methylprednisolone  Methylprednisolone  💬
 | Methylprednisolone | 002 [46]  2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
 | 
| 470 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
NR3C1 [1] NR3C1 💬
 | 
Prednisone  Prednisone  💬
 | Prednisone | 002 [45]  2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
 | 
| 471 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
OPRM1 [1] OPRM1 💬
 | 
Morphine  Morphine  💬
 | Morphine | 036 [5] 36, 46, 70, 85, 86 💬
 | 
| 472 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Beraprost  Beraprost  💬
 | Beraprost | 086 [1] 86 💬
 | 
| 473 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Epoprostenol  Epoprostenol  💬
 | Epoprostenol | 086 [1] 86 💬
 | 
| 474 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Iloprost  Iloprost  💬
 | Iloprost | 051 [4] 51, 84, 85, 86 💬
 | 
| 475 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Ralinepag  Ralinepag  💬
 | Ralinepag | 086 [1] 86 💬
 | 
| 476 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Selexipag  Selexipag  💬
 | Selexipag | 051 [5] 51, 70, 84, 86, 88 💬
 | 
| 477 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Treprostinil  Treprostinil  💬
 | Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
 | 
| 478 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases  | 
TRPV1 [1] TRPV1 💬
 | 
Capsaicin  Capsaicin  💬
 | Capsaicin | 006 [3]  6 , 86, 226 💬
 | 
| 479 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 480 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 481 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 482 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 483 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 484 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 485 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 486 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases  | 
PARP1 [1] PARP1 💬
 | 
Olaparib  Olaparib  💬
 | Olaparib | 086 [2] 86, 285 💬
 | 
| 487 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 488 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 489 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 18 diseases  | 
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬
 | 
Acetazolamide  Acetazolamide  💬
 | Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
 | 
| 490 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 491 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 492 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 493 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 494 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 495 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases  | 
BRAF [3] BRAF, RAF1, RET 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 496 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 497 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases  | 
RRM2 [1] RRM2 💬
 | 
Hydroxyurea  Hydroxyurea  💬
 | Hydroxyurea | 003 [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 498 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases  | 
AR [1] AR 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 499 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 500 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 501 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases  | 
CYP19A1 [1] CYP19A1 💬
 | 
Anastrozole  Anastrozole  💬
 | Anastrozole | 078 [3] 78, 86, 193 💬
 | 
| 502 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 503 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 504 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases  | 
ATP4A [2] ATP4A, ATP4B 💬
 | 
Esomeprazole  Esomeprazole  💬
 | Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
 | 
| 505 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 506 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 507 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 508 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 509 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 510 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 511 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 512 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 513 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases  | 
RRM2 [1] RRM2 💬
 | 
Hydroxyurea  Hydroxyurea  💬
 | Hydroxyurea | 003 [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 514 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 515 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 516 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 517 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases  | 
CA2 [1] CA2 💬
 | 
Acetazolamide  Acetazolamide  💬
 | Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
 | 
| 518 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases  | 
SLC12A2 [1] SLC12A2 💬
 | 
Furosemide  Furosemide  💬
 | Furosemide | 006 [2]  6 , 86 💬
 | 
| 519 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 520 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 521 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases  | 
DRD2 [1] DRD2 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 522 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases  | 
DRD2 [1] DRD2 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 523 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases  | 
KEAP1 [1] KEAP1 💬
 | 
Dimethyl fumarate  Dimethyl fumarate  💬
 | Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬
 | 
| 524 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 525 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 526 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 527 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 528 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
ABL1 [3] ABL1, KIT, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 529 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 530 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 531 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 532 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
AR [3] AR, ESR1, ESR2 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 533 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
BRAF [7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 534 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Ambrisentan  Ambrisentan  💬
 | Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
 | 
| 535 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Sitaxentan  Sitaxentan  💬
 | Sitaxentan | 086 [1] 86 💬
 | 
| 536 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 537 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 538 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
EDNRA [2] EDNRA, EDNRB 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 539 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 540 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 541 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 542 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 543 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
KEAP1 [1] KEAP1 💬
 | 
Dimethyl fumarate  Dimethyl fumarate  💬
 | Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬
 | 
| 544 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 545 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
NQO1 [1] NQO1 💬
 | 
Warfarin  Warfarin  💬
 | Warfarin | 006 [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 | 
| 546 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 547 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 548 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 549 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 550 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 551 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 552 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 553 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 554 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 555 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 556 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 557 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 558 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 559 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 560 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 561 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
AVPR1A [2] AVPR1A, AVPR2 💬
 | 
Conivaptan  Conivaptan  💬
 | Conivaptan | 086 [1] 86 💬
 | 
| 562 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
AVPR2 [1] AVPR2 💬
 | 
Tolvaptan  Tolvaptan  💬
 | Tolvaptan | 067 [4] 67, 72, 86, 225 💬
 | 
| 563 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 564 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
KIT [2] KIT, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 565 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
KIT [3] KIT, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 566 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
KIT [3] KIT, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 567 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 568 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 569 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 570 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 571 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 572 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
KIT [2] KIT, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 573 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
KIT [3] KIT, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 574 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 575 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 576 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases  | 
PRL [1] PRL 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 577 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 578 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
P2RY12 [1] P2RY12 💬
 | 
Clopidogrel  Clopidogrel  💬
 | Clopidogrel | 049 [3] 49, 51, 86 💬
 | 
| 579 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
P2RY12 [1] P2RY12 💬
 | 
Clopidogrel hydrochloride Clopidogrel hydrochloride 💬
 | Clopidogrel | 049 [3] 49, 51, 86 💬
 | 
| 580 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
P2RY12 [1] P2RY12 💬
 | 
Clopidogrel besilate Clopidogrel besilate 💬
 | Clopidogrel | 049 [3] 49, 51, 86 💬
 | 
| 581 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Beraprost  Beraprost  💬
 | Beraprost | 086 [1] 86 💬
 | 
| 582 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Epoprostenol  Epoprostenol  💬
 | Epoprostenol | 086 [1] 86 💬
 | 
| 583 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Iloprost  Iloprost  💬
 | Iloprost | 051 [4] 51, 84, 85, 86 💬
 | 
| 584 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Ralinepag  Ralinepag  💬
 | Ralinepag | 086 [1] 86 💬
 | 
| 585 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Selexipag  Selexipag  💬
 | Selexipag | 051 [5] 51, 70, 84, 86, 88 💬
 | 
| 586 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Treprostinil  Treprostinil  💬
 | Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
 | 
| 587 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGS1 [1] PTGS1 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 588 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases  | 
PTGS1 [1] PTGS1 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 589 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 590 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 591 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 592 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 593 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 594 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 595 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases  | 
ESR1 [2] ESR1, ESR2 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 596 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases  | 
PRL [1] PRL 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 597 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 598 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
AR [1] AR 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 599 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
BRAF [3] BRAF, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 600 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 601 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
IL1R2 [1] IL1R2 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 602 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 603 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 604 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 605 | Protein processing in endoplasmic reticulum 💬 3 genes, 3 drugs (DrugBank) and 3 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 606 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
BRAF [3] BRAF, KDR, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 607 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 608 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 609 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
ESR1 [1] ESR1 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 610 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 611 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 19 diseases  | 
CA2 [2] CA2, CA4 💬
 | 
Acetazolamide  Acetazolamide  💬
 | Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
 | 
| 612 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 613 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Sildenafil  Sildenafil  💬
 | Sildenafil | 006 [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
 | 
| 614 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Tadalafil  Tadalafil  💬
 | Tadalafil | 006 [7]  6 , 51, 75, 84, 86, 113, 210 💬
 | 
| 615 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Udenafil  Udenafil  💬
 | Udenafil | 086 [2] 86, 210 💬
 | 
| 616 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
PDE5A [1] PDE5A 💬
 | 
Vardenafil  Vardenafil  💬
 | Vardenafil | 013 [3] 13, 86, 299 💬
 | 
| 617 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases  | 
RRM2 [1] RRM2 💬
 | 
Hydroxyurea  Hydroxyurea  💬
 | Hydroxyurea | 003 [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 618 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases  | 
RRM2 [1] RRM2 💬
 | 
Hydroxyurea  Hydroxyurea  💬
 | Hydroxyurea | 003 [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 619 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
BRAF [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 620 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
DRD2 [1] DRD2 💬
 | 
Lisuride  Lisuride  💬
 | Lisuride | 006 [2]  6 , 86 💬
 | 
| 621 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
DRD2 [1] DRD2 💬
 | 
Terguride  Terguride  💬
 | Terguride | 051 [2] 51, 86 💬
 | 
| 622 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 623 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
KIT [2] KIT, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 624 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases  | 
KIT [3] KIT, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 625 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases  | 
ABL1 [3] ABL1, KIT, PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 626 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases  | 
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 627 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 628 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases  | 
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 629 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases  | 
BRAF [3] BRAF, PDGFRB, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 630 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 631 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases  | 
PDGFRA [1] PDGFRA 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 632 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases  | 
PDGFRA [2] PDGFRA, PDGFRB 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 633 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 634 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 635 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
ADRB1 [2] ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 636 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 637 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 638 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 639 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases  | 
EDNRB [1] EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 640 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases  | 
EDNRB [1] EDNRB 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 641 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases  | 
EDNRB [1] EDNRB 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 642 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 643 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 644 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 645 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
ACE [1] ACE 💬
 | 
Captopril  Captopril  💬
 | Captopril | 006 [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
 | 
| 646 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 647 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 648 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
ADRB1 [2] ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 649 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 650 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 651 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 652 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 653 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 654 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Ambrisentan  Ambrisentan  💬
 | Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
 | 
| 655 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 656 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 657 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 658 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Sitaxentan  Sitaxentan  💬
 | Sitaxentan | 086 [1] 86 💬
 | 
| 659 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 660 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases  | 
ACE [1] ACE 💬
 | 
Captopril  Captopril  💬
 | Captopril | 006 [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
 | 
| 661 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases  | 
AGTR1 [2] AGTR1, AGTR2 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 662 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases  | 
AGTR1 [2] AGTR1, AGTR2 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 663 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases  | 
ANPEP [1] ANPEP 💬
 | 
Ubenimex  Ubenimex  💬
 | Ubenimex | 086 [1] 86 💬
 | 
| 664 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 665 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 666 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 667 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 668 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases  | 
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 669 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Bisoprolol  Bisoprolol  💬
 | Bisoprolol | 058 [4] 58, 67, 86, 113 💬
 | 
| 670 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases  | 
ADRB1 [1] ADRB1 💬
 | 
Dobutamine  Dobutamine  💬
 | Dobutamine | 057 [4] 57, 58, 86, 215 💬
 | 
| 671 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases  | 
ADRB2 [1] ADRB2 💬
 | 
Albuterol  Albuterol  💬
 | Salbutamol | 003 [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
 | 
| 672 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 673 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases  | 
SLC12A2 [1] SLC12A2 💬
 | 
Furosemide  Furosemide  💬
 | Furosemide | 006 [2]  6 , 86 💬
 | 
| 674 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 675 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 676 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 677 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 678 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 679 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases  | 
PTGS1 [2] PTGS1, PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 680 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases  | 
SLC6A4 [1] SLC6A4 💬
 | 
Fluoxetine  Fluoxetine  💬
 | Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬
 | 
| 681 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases  | 
EGFR [1] EGFR 💬
 | 
Cetuximab  Cetuximab  💬
 | Cetuximab | 051 [2] 51, 86 💬
 | 
| 682 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 683 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 684 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases  | 
ACVR2A [1] ACVR2A 💬
 | 
Sotatercept  Sotatercept  💬
 | Sotatercept | 086 [2] 86, 284 💬
 | 
| 685 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 686 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 687 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 688 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 689 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 690 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 691 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 692 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases  | 
CYP19A1 [1] CYP19A1 💬
 | 
Anastrozole  Anastrozole  💬
 | Anastrozole | 078 [3] 78, 86, 193 💬
 | 
| 693 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases  | 
SLC6A4 [1] SLC6A4 💬
 | 
Fluoxetine  Fluoxetine  💬
 | Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬
 | 
| 694 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 695 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases  | 
CACNA1C [1] CACNA1C 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 696 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases  | 
CACNA1C [1] CACNA1C 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 697 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases  | 
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
 | 
Lidocaine  Lidocaine  💬
 | Lidocaine | 006 [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
 | 
| 698 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases  | 
SCN2A [3] SCN2A, SCN3A, SCN9A 💬
 | 
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬
 | Lidocaine | 006 [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
 | 
| 699 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases  | 
TAS1R2 [2] TAS1R2, TAS1R3 💬
 | 
Aspartame  Aspartame  💬
 | Aspartame | 006 [4]  6 , 13, 67, 86 💬
 | 
| 700 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases  | 
HMGCR [1] HMGCR 💬
 | 
Simvastatin  Simvastatin  💬
 | Simvastatin | 006 [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
 | 
| 701 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases  | 
ACVR2A [1] ACVR2A 💬
 | 
Sotatercept  Sotatercept  💬
 | Sotatercept | 086 [2] 86, 284 💬
 | 
| 702 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases  | 
IL1R1 [1] IL1R1 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 703 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 704 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 | 
| 705 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 706 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 707 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 708 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 709 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 710 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases  | 
BRAF [2] BRAF, RET 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 711 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 712 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases  | 
ESR1 [1] ESR1 💬
 | 
Fulvestrant  Fulvestrant  💬
 | Fulvestrant | 049 [2] 49, 86 💬
 | 
| 713 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases  | 
ESR1 [1] ESR1 💬
 | 
Prasterone  Prasterone  💬
 | Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬
 | 
| 714 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 715 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 716 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases  | 
CACNA1D [1] CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 717 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases  | 
CACNA1D [1] CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 718 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 719 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases  | 
PRKAA1 [2] PRKAA1, PRKAA2 💬
 | 
Metformin  Metformin  💬
 | Metformin | 002 [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
 | 
| 720 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases  | 
MAP3K5 [1] MAP3K5 💬
 | 
Selonsertib  Selonsertib  💬
 | Selonsertib | 086 [1] 86 💬
 | 
| 721 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 722 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 723 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases  | 
FLT3 [1] FLT3 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 724 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases  | 
IL1R2 [1] IL1R2 💬
 | 
Anakinra  Anakinra  💬
 | Anakinra | 002 [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 | 
| 725 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases  | 
PPARG [1] PPARG 💬
 | 
Pioglitazone  Pioglitazone  💬
 | Pioglitazone | 002 [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 | 
| 726 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases  | 
RAF1 [1] RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 727 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 728 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases  | 
CACNA1C [2] CACNA1C, CACNA1D 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 729 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases  | 
MTOR [1] MTOR 💬
 | 
Sirolimus  Sirolimus  💬
 | Sirolimus | 002 [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 730 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases  | 
NQO1 [2] NQO1, VKORC1 💬
 | 
Warfarin  Warfarin  💬
 | Warfarin | 006 [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 | 
| 731 | Ubiquitin mediated proteolysis 💬 2 genes, 2 drugs (DrugBank) and 11 diseases  | 
KEAP1 [1] KEAP1 💬
 | 
Dimethyl fumarate  Dimethyl fumarate  💬
 | Dimethyl fumarate | 013 [5] 13, 49, 51, 86, 296 💬
 | 
| 732 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬
 | 
Carvedilol  Carvedilol  💬
 | Carvedilol | 057 [4] 57, 86, 113, 210 💬
 | 
| 733 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 734 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
AGTR1 [1] AGTR1 💬
 | 
Angiotensin II  Angiotensin II  💬
 | Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 735 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
AVPR1A [1] AVPR1A 💬
 | 
Conivaptan  Conivaptan  💬
 | Conivaptan | 086 [1] 86 💬
 | 
| 736 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
BRAF [2] BRAF, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 737 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Diltiazem  Diltiazem  💬
 | Diltiazem | 051 [3] 51, 58, 86 💬
 | 
| 738 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
 | 
Nicardipine  Nicardipine  💬
 | Nicardipine | 070 [2] 70, 86 💬
 | 
| 739 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Ambrisentan  Ambrisentan  💬
 | Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬
 | 
| 740 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 741 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Bosentan  Bosentan  💬
 | Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 | 
| 742 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Macitentan  Macitentan  💬
 | Macitentan | 051 [5] 51, 85, 86, 88, 210 💬
 | 
| 743 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
EDNRA [1] EDNRA 💬
 | 
Sitaxentan  Sitaxentan  💬
 | Sitaxentan | 086 [1] 86 💬
 | 
| 744 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬
 | 
Riociguat  Riociguat  💬
 | Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬
 | 
| 745 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Beraprost  Beraprost  💬
 | Beraprost | 086 [1] 86 💬
 | 
| 746 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Epoprostenol  Epoprostenol  💬
 | Epoprostenol | 086 [1] 86 💬
 | 
| 747 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Iloprost  Iloprost  💬
 | Iloprost | 051 [4] 51, 84, 85, 86 💬
 | 
| 748 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Ralinepag  Ralinepag  💬
 | Ralinepag | 086 [1] 86 💬
 | 
| 749 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Selexipag  Selexipag  💬
 | Selexipag | 051 [5] 51, 70, 84, 86, 88 💬
 | 
| 750 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases  | 
PTGIR [1] PTGIR 💬
 | 
Treprostinil  Treprostinil  💬
 | Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬
 | 
| 751 | Vasopressin-regulated water reabsorption 💬 1 gene, 6 drugs (DrugBank) and 10 diseases  | 
AVPR2 [1] AVPR2 💬
 | 
Conivaptan  Conivaptan  💬
 | Conivaptan | 086 [1] 86 💬
 | 
| 752 | Vasopressin-regulated water reabsorption 💬 1 gene, 6 drugs (DrugBank) and 10 diseases  | 
AVPR2 [1] AVPR2 💬
 | 
Tolvaptan  Tolvaptan  💬
 | Tolvaptan | 067 [4] 67, 72, 86, 225 💬
 | 
| 753 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases  | 
KDR [2] KDR, RAF1 💬
 | 
Sorafenib  Sorafenib  💬
 | Sorafenib | 034 [2] 34, 86 💬
 | 
| 754 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Acetaminophen  Acetaminophen  💬
 | Acetaminophen | 003 [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
 | 
| 755 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases  | 
PTGS2 [1] PTGS2 💬
 | 
Aspirin  Aspirin  💬
 | Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
 | 
| 756 | Vibrio cholerae infection 💬 3 genes, 10 drugs (DrugBank) and 8 diseases  | 
SLC12A2 [1] SLC12A2 💬
 | 
Furosemide  Furosemide  💬
 | Furosemide | 006 [2]  6 , 86 💬
 | 
| 757 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases  | 
ABL1 [1] ABL1 💬
 | 
Imatinib  Imatinib  💬
 | Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 | 
| 758 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases  | 
ABL1 [1] ABL1 💬
 | 
Nilotinib  Nilotinib  💬
 | Nilotinib | 006 [5]  6 ,  8 , 34, 51, 86 💬
 | 
| 759 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases  | 
IL6R [1] IL6R 💬
 | 
Satralizumab  Satralizumab  💬
 | Satralizumab | 011 [3] 11, 13, 86 💬
 | 
| 760 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases  | 
IL6R [1] IL6R 💬
 | 
Tocilizumab  Tocilizumab  💬
 | Tocilizumab | 002 [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
 |